Hypothermia and neonatal encephalopathy.

Academic Article


  • Data from large randomized clinical trials indicate that therapeutic hypothermia, using either selective head cooling or systemic cooling, is an effective therapy for neonatal encephalopathy. Infants selected for cooling must meet the criteria outlined in published clinical trials. The implementation of cooling needs to be performed at centers that have the capability to manage medically complex infants. Because the majority of infants who have neonatal encephalopathy are born at community hospitals, centers that perform cooling should work with their referring hospitals to implement education programs focused on increasing the awareness and identification of infants at risk for encephalopathy, and the initial clinical management of affected infants.
  • Authors

    Published In

  • Pediatrics  Journal
  • Keywords

  • Asphyxia Neonatorum, Cooperative Behavior, Follow-Up Studies, Hospitals, Community, Humans, Hypothermia, Induced, Hypoxia-Ischemia, Brain, Infant, Newborn, Infant, Premature, Diseases, Interdisciplinary Communication, Randomized Controlled Trials as Topic, Referral and Consultation, Risk Assessment, Survival Rate
  • Digital Object Identifier (doi)

    Author List

  • Committee on Fetus and Newborn; Papile L-A; Baley JE; Benitz W; Cummings J; Carlo WA; Eichenwald E; Kumar P; Polin RA; Tan RC
  • Start Page

  • 1146
  • End Page

  • 1150
  • Volume

  • 133
  • Issue

  • 6