The use of 111Ag as a tool for studying biological distribution of silver-based antimicrobials.

Academic Article

Abstract

  • Recently, there has been an emergence of significant interest in silver-based antimicrobials. Our goal was to develop a radioactive tracer for investigating the biological fate of such compounds. Purified 111Ag was incorporated into the methylated caffeine analogue, IC1 to yield the silver carbene complex designated as [111Ag]SCC1 and investigated in biodistribution studies.
  • Authors

    Published In

  • MedChemComm  Journal
  • Digital Object Identifier (doi)

    Authorlist

  • Aweda TA; Ikotun O; Mastren T; Cannon CL; Wright B; Youngs WJ; Cutler C; Guthrie J; Lapi SE
  • Start Page

  • 1015
  • End Page

  • 1017
  • Volume

  • 4
  • Issue

  • 6