Alcoholic hepatitis-A clinical and pathological study of 142 cases

Academic Article


  • One hundred forty two cases of alcoholic hepatitis admitted to the Boston City Hospital over a 5 yr period were analyzed. The data showed that clinical signs, symptoms and laboratory features are not specific for alcoholic hepatitis and a correct diagnosis can only be made histologically. Furthermore, there was poor correlation between histology and various biochemical parameters. Of these patients 43% were not jaundiced indicating that hyperbilirubinemia is neither necessary nor sufficient for the diagnosis of alcoholic hepatitis. In patients who had a combination of serum bilirubin > 2.0 mg/dl, serum albumin < 2.5 g/dl, prothrombin time prolongation > 5 sec, the mortality rate was 75%. © 1978.
  • Published In

    Digital Object Identifier (doi)

    Author List

  • Mihas AA; Doos WG; Spenney JG
  • Start Page

  • 461
  • End Page

  • 472
  • Volume

  • 31
  • Issue

  • 6-7