Gastrin stimulated H+ secretion in amphibian gastric mucosa: Effect of tetrodotoxin

Academic Article


  • The role of neural mechanisms in gastrin stimulated H+ secretion was studied using amphibian gastric fundic mucosa. Spontaneously secreting mucosae were converted to resting state (zero H+ secretory rate) using Burimamide. Following removal of burimamide, 3×10-6 M tetrodotoxin did not block gastrin stimulation of H+ secretion indicating that neural mechanisms are not required. © 1978 Birkhäuser Verlag.
  • Published In

  • Experientia  Journal
  • Digital Object Identifier (doi)

    Author List

  • Spenney JG
  • Start Page

  • 625
  • End Page

  • 626
  • Volume

  • 34
  • Issue

  • 5