Donor transmission of malignant melanoma in a lung transplant recipient 32 years after curative resection.

Academic Article

Abstract

  • In the current era of organ shortages and long wait times for life-saving transplants, marginal or extended donors are increasingly being considered; one such category of marginal organs is from donors with a previous history of malignancy. Melanoma in particular has been associated with increased risk of developing late recurrence. In this report, we describe a case of fatal donor melanoma transmission to a 64-year-old lung transplant recipient 32 years after surgical excision of the melanoma. Based on this report and review of the available literature, we conclude that a history of donor melanoma, regardless of the stage and time interval from 'curative' surgical resection, should remain a strong relative contraindication to transplantation.
  • Published In

    Keywords

  • Donor Selection, Fatal Outcome, Female, Humans, Lung Neoplasms, Lung Transplantation, Male, Melanoma, Middle Aged, Pulmonary Fibrosis, Skin Neoplasms, Tissue Donors
  • Digital Object Identifier (doi)

    Author List

  • Bajaj NS; Watt C; Hadjiliadis D; Gillespie C; Haas AR; Pochettino A; Mendez J; Sterman DH; Schuchter LM; Christie JD
  • Start Page

  • e26
  • End Page

  • e31
  • Volume

  • 23
  • Issue

  • 7