Well differentiated astrocytoma occurring nine years after radiation therapy for medulloblastoma.

Academic Article

Abstract

  • Conventional treatment for medulloblastoma includes surgical resection followed by craniospinal irradiation, with the potential risk of subsequent radiotherapy-induced secondary neoplasms. We report a 23-year-old woman previously irradiated nine years earlier for a cerebellar medulloblastoma who developed a new enhancing lesion in the primary radiation field four weeks following completion of high dose chemotherapy with bone marrow transplantation for recurrent disease. Resection of this lesion revealed a low grade glioma with no evidence of recurrent medulloblastoma.
  • Authors

    Published In

    Keywords

  • Adult, Astrocytoma, Cerebellar Neoplasms, Cerebellum, Chemotherapy, Adjuvant, Combined Modality Therapy, Cranial Irradiation, Female, Follow-Up Studies, Humans, Magnetic Resonance Imaging, Medulloblastoma, Neoplasm Recurrence, Local, Neoplasms, Multiple Primary, Neoplasms, Radiation-Induced, Radiotherapy, Adjuvant
  • Author List

  • Osumi AK; Mclendon RE; Tien RD; Friedman HS; Graham M; Hockenberger B; Halperin EC; Oakes WJ
  • Start Page

  • 281
  • End Page

  • 285
  • Volume

  • 13
  • Issue

  • 5