Techniques for measuring renal transit time

Academic Article

Abstract

  • A variety of techniques have been used for quantitative estimation of renal transit time. We compared different indices of transit time in a group of 30 patients having baseline and ACE inhibitor technetium-99m mercaptoacetyltriglycine (MAG3) renography prior to arteriography: peak time, mean transit time, and the ratio of background-subtracted counts at 20 min to those at 3 min. Each index was calculated from whole-kidney ROI, cortical ROI, and cortical factor (by factor analysis). The strongest correlations between angiographic percent of stenosis and transit time index were observed for the peak time (Spearman ρ=0.469, n=53, P <0.005) and for the R20/3 (again ρ=0.469, n=53, P <0.005) using the whole-kidney ROI and using only the baseline data without captopril. (Spearman's ρ is simply the correlation coefficient calculated from rank in list, which allows for nonlinear correlation.) Thus simple indices of transit time (whole-kidney peak time and R20/3) correlated as well with the observed pathology as did more complicated methods that required deconvolution, factor analysis, or selection of a cortical ROI. © 1995 Springer-Verlag.
  • Authors

    Digital Object Identifier (doi)

    Author List

  • Russell CD; Japanwalla M; Khan S; Scott JW; Dubovsky EV
  • Start Page

  • 1372
  • End Page

  • 1378
  • Volume

  • 22
  • Issue

  • 12