Primary hyperparathyroidism-related brown tumors mimicking other giant cell-containing skeletal tumors: Role of correlative imaging in diagnosis

Academic Article


  • A patient initially suspected of having a giant cell granuloma was subsequently found-through additional imaging with 99mTc-sestamibi and ultrasound-to have osteolytic brown tumors caused by a parathyroid adenoma. Brown tumors that relate to primary hyperparathyroidism may mimic other skeletal tumors that contain giant cells, presenting difficulty with accurate diagnosis. Correlative imaging can have a valuable role in such cases, potentially avoiding the extensive work-up usually done for suspected bone metastases. © 2013 by the Society of Nuclear Medicine and Molecular Imaging, Inc.
  • Digital Object Identifier (doi)

    Author List

  • Manzil FFP; Bhambhvani P; Vattoth S; Subedi SK; Bag AK; O'Malley JP
  • Start Page

  • 46
  • End Page

  • 48
  • Volume

  • 41
  • Issue

  • 1