2,4-Diamino-6-(bis-2-chloroethyl)aminomethyl pteridine - A new potent anticancer drug

Academic Article

Abstract

  • 2,4-Diamino-6-(bis-2-chloroethyl)aminomethyl pteridine has been synthesized and found to be highly potent against L-1210 mouse leukemia lymphoblasts. A single dose of 5 mg/kg injected 24 h after the tumor inoculation increased the life-span of 50% of mice to more than 200%, while the other 505 of animals were cured. © 1984 Springer-Verlag.
  • Authors

    Published In

    Digital Object Identifier (doi)

    Pubmed Id

  • 20890808
  • Author List

  • Khaled MA; Morin RD; Benington F; Daugherty JP
  • Start Page

  • 73
  • End Page

  • 74
  • Volume

  • 13
  • Issue

  • 2