Induction of the plateau phase and rescue of MOPC 104e by nonspecific immunization

Academic Article


  • The enhancement of MOPC 104E myeloma growth by nonspecific immunostimulation with C. parvum or immunization with sheep red blood cells and levan mixture was evaluated in BALB/c mice. We observed increased levels of serum MOPC 104E IgMand early mortality in the tumor-bearing mice following treatment with C. parvum or antigenic stimulation. The enhancement of tumor growth observed was due to the production of lymphokine mitogenic factors produced in response to the nonspecific immunostimulation. © 1986 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
  • Published In

    Digital Object Identifier (doi)

    Author List

  • Ghanta VK; Shrestha K; Hiramoto RN
  • Start Page

  • 525
  • End Page

  • 533
  • Volume

  • 4
  • Issue

  • 6