Ureaplasma infection and neonatal lung disease.

Academic Article

Abstract

  • Infection with the ureaplasmas may occur in utero or perinatally in prematurely born infants. For some infants, infection with these organisms triggers a vigorous pro-inflammatory response in the lungs and increases the risk of developing bronchopulmonary dysplasia (BPD). At present, there is insufficient evidence from clinical trials to determine whether antibiotic treatment of Ureaplasma has any influence on the development of BPD and its comorbidities. Future investigation in the context of well-designed, adequately powered controlled clinical trials should focus on determining whether treatment of ureaplasmal infection lessens lung inflammation, decreases rates of BPD, and improves long-term, neurodevelopmental outcome.
  • Authors

    Published In

    Keywords

  • Anti-Bacterial Agents, Bronchopulmonary Dysplasia, Chorioamnionitis, Erythromycin, Female, Humans, Infant, Newborn, Infectious Disease Transmission, Vertical, Pregnancy, Premature Birth, Ureaplasma, Ureaplasma Infections
  • Digital Object Identifier (doi)

    Author List

  • Schelonka RL; Waites KB
  • Start Page

  • 2
  • End Page

  • 9
  • Volume

  • 31
  • Issue

  • 1