Comparative in vitro susceptibilities of human mycoplasmas and ureaplasmas to a new investigational ketolide, CEM-101.

Academic Article

Abstract

  • MICs were determined for an investigational ketolide, CEM-101, and azithromycin, telithromycin, doxycycline, levofloxacin, clindamycin, and linezolid against 36 Mycoplasma pneumoniae, 5 Mycoplasma genitalium, 13 Mycoplasma hominis, 15 Mycoplasma fermentans, and 20 Ureaplasma isolates. All isolates, including two macrolide-resistant M. pneumoniae isolates, were inhibited by CEM-101 at < or = 0.5 microg/ml, making CEM-101 the most potent compound tested.
  • Authors

    Published In

    Keywords

  • Anti-Bacterial Agents, Drug Resistance, Bacterial, Humans, Ketolides, Microbial Sensitivity Tests, Mycoplasma, Mycoplasma Infections, Mycoplasma fermentans, Mycoplasma genitalium, Mycoplasma pneumoniae, Ureaplasma, Ureaplasma Infections
  • Digital Object Identifier (doi)

    Author List

  • Waites KB; Crabb DM; Duffy LB
  • Start Page

  • 2139
  • End Page

  • 2141
  • Volume

  • 53
  • Issue

  • 5