Antimicrobial resistance in gram-negative bacteria isolated from the urinary tract in community-residing persons with spinal cord injury.

Academic Article

Abstract

  • OBJECTIVE: To assess the epidemiology of antimicrobial resistance among community-residing persons with spinal cord injury (SCI). DESIGN: Retrospective analysis of existing data. SETTING: Data were obtained from persons with SCI attending clinic for annual examinations. PARTICIPANTS: Two hundred eighty-seven SCI outpatients. INTERVENTION: None. MAIN OUTCOME MEASURE: Occurrence of bacteriuria with gram-negative organisms demonstrating resistance to antimicrobial agents in 2 or more classes. RESULTS: There were 706 gram-negative isolates from 444 urine specimens. Resistance to drugs in 2 or more classes occurred in 33% of bacterial isolates, but did not significantly increase in frequency among those injured for longer periods or more severely. Significantly higher rates of multidrug-resistant bacteria occurred in specimens from males, younger age group (< or =45 yrs), and persons with indwelling and condom catheters. CONCLUSIONS: Antimicrobial resistance in outpatients with SCI is common and is related to widespread use of specific drugs, type of bladder management, and other host factors.
  • Authors

    Keywords

  • Adult, Alabama, Community Health Services, Drug Resistance, Multiple, Ethnic Groups, Female, Gram-Negative Bacteria, Humans, Injury Severity Score, Male, Microbial Sensitivity Tests, Retrospective Studies, Spinal Cord Injuries, Urinary Tract Infections
  • Author List

  • Waites KB; Chen Y; DeVivo MJ; Canupp KC; Moser SA
  • Start Page

  • 764
  • End Page

  • 769
  • Volume

  • 81
  • Issue

  • 6