Molecular typing of Mycobacterium tuberculosis strains with a common two-band IS6110 pattern.

Academic Article

Abstract

  • We conducted a program of population-based molecular typing of all Mycobacterium tuberculosis isolates obtained in Alabama since 1994. Of 2452 isolates, 1013 (41%) had fewer than 6 bands of IS6110; 348 (14%) had a single two-band pattern (JH2). With conventional epidemiologic methods, we identified three groups of related patients with JH2 isolates. Spoligotyping and pattern of variable number of tandem repeats identified 10 molecular groups; two found by conventional methods were subdivided.
  • Published In

    Keywords

  • Alabama, Bacterial Typing Techniques, DNA Fingerprinting, Drug Resistance, Bacterial, Genetic Variation, Humans, Molecular Epidemiology, Mycobacterium tuberculosis, Tuberculosis
  • Digital Object Identifier (doi)

    Author List

  • Lok KH; Benjamin WH; Kimerling ME; Pruitt V; Mulcahy D; Robinson N; Keenan NB; Dunlap NE
  • Start Page

  • 1303
  • End Page

  • 1305
  • Volume

  • 8
  • Issue

  • 11