Tin(IV) chloride mediated glycosylation in arabinofuranose, galactofuranose and rhamnopyranose

Academic Article

Abstract

  • Using tin(IV) chloride, O-glycosylation reactions were performed on peracylated D-arabinofuranose, D-galactofuranose and L-rhamnofuranose as well as 1-bromo-D-arabinofuranoses at room temperature in good anomeric purities and yields. In these circumstances, this coupling method has certain advantages over standard glycosylation reactions, such as the Koenigs-Knorr methods which use the 1-halosugar (synthesized from the 1-acyl derivative) and toxic mercury salts as the coupling agent.
  • Published In

    Digital Object Identifier (doi)

    Author List

  • Pathak AK; El-Kattan YA; Bansal N; Maddry JA; Reynolds RC
  • Start Page

  • 1497
  • End Page

  • 1500
  • Volume

  • 39
  • Issue

  • 12