Using tin(IV) chloride, O-glycosylation reactions were performed on peracylated D-arabinofuranose, D-galactofuranose and L-rhamnofuranose as well as 1-bromo-D-arabinofuranoses at room temperature in good anomeric purities and yields. In these circumstances, this coupling method has certain advantages over standard glycosylation reactions, such as the Koenigs-Knorr methods which use the 1-halosugar (synthesized from the 1-acyl derivative) and toxic mercury salts as the coupling agent.
