Indirect effects of pneumococcal conjugate vaccines in national immunization programs for children on adult pneumococcal disease

Academic Article


  • © 2016 by The Korean Society of Infectious Diseases | Korean Society for Chemotherapy. The pneumococcal conjugate vaccine (PCV) was developed to overcome the limitations of the pneumococcal polysaccharide vaccine, which produces poor immunogenicity in infants younger than 2 years. As many countries have included PCVs in national immunization programs for children, the incidence of invasive pneumococcal disease caused by vaccine type Streptococcus pneumoniae has declined markedly, not only among the vaccinated pediatric population, but also among unvaccinated adults. In this review, we present a concise overview of the indirect effects of mass pediatric PCV immunization on unvaccinated adults.
  • Authors

    Digital Object Identifier (doi)

    Author List

  • Kim YK; LaFon D; Nahm MH
  • Start Page

  • 257
  • End Page

  • 266
  • Volume

  • 48
  • Issue

  • 4