Co-occurring risk factors in multiple sclerosis

Academic Article

Abstract

  • Objective: We examined individual and co-occurring risk factors as correlates of health outcomes in persons with multiple sclerosis (MS). Methods: Sixty-nine participants with MS completed measures of nutrition, physical activity levels, comorbidity and neuroperformance. The data were analyzed using t-test analyses in SPSS Statistics 22.0. Results: Total number of comorbidities (z = 2.36, p = .02), cardiovascular disease symptoms (z = 2.63, p = .01), Timed 25-Foot Walk (T25FW) speed (z = 2.53, p = .01), and 6 Minute Walk (6MW) distance (z = 2.61, p = .01) had significant differences in the cluster of co-occurring poor nutrition and insufficient levels of physical activity. There was a significant difference between those reporting two vs. one risk factor for number of comorbidities (z = 2.41, p = .02), cardiovascular disease symptoms (z = 2.40 p = .02), T25FW speed (z = 2.39, p = .02), and 6MW distance (z = 2.68, p = .01). Conclusions: These results suggest that: (1) the cluster of co-occurring poor diet and insufficient physical activity is associated with comorbidities and neuroperformance markers; and (2) that cluster is further synergistically associated with comorbidities and neuroperformance markers.
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    Digital Object Identifier (doi)

    Author List

  • Balto JM; Ensari I; Hubbard EA; Khan N; Barnes JL; Motl RW
  • Start Page

  • 76
  • End Page

  • 83
  • Volume

  • 41
  • Issue

  • 1