Positions

Selected Publications

Academic Article

Year Title Altmetric
2018 Modular Self-Assembly of Protein Cage Lattices for Multistep CatalysisACS Nano.  12:942-953. 2018
2017 Pathways for gold nucleation and growth over protein cagesLangmuir.  33:5925-5931. 2017
2017 Targeted mutagenesis of the P22 portal protein reveals the mechanism of signal transmission during DNA packagingVirology.  505:127-138. 2017
2017 Self-assembly of P22 protein cages with polyamidoamine dendrimer and inorganic nanoparticlesJournal of Materials Research.  32:465-472. 2017
2017 φX174 procapsid assembly: Effects of an inhibitory external scaffolding protein and resistant coat proteins in vitroJournal of Virology.  91. 2017
2016 Poxvirus uracil-DNA glycosylase—An unusual member of the family I uracil-DNA glycosylasesProtein Science.  25:2113-2131. 2016
2016 Detecting asymmetry in the presence of symmetry with maximum likelihood threedimensional reconstructions of viruses from electron microscope imagesIET Image Processing.  10:624-629. 2016
2016 Follow the Yellow Brick Road: A Paradigm Shift in Virus AssemblyJournal of Molecular Biology.  428:416-418. 2016
2016 Identification of the calmodulin-binding domains of Fas death receptorPLoS ONE.  11. 2016
2016 Cyclophilin A stabilizes the HIV-1 capsid through a novel non-canonical binding siteNature Communications.  7. 2016
2016 Structural plasticity of the protein plug that traps newly packaged genomes in podoviridae virionsJournal of Biological Chemistry.  291:215-226. 2016
2015 A multilaboratory comparison of calibration accuracy and the performance of external references in analytical ultracentrifugationPLoS ONE.  10. 2015
2015 P22 virus-like particles constructed Au/CdS plasmonic photocatalytic nanostructures for enhanced photoactivityChemical Communications.  51:1062-1065. 2015
2015 Selective biotemplated synthesis of TiO2 inside a protein cageBiomacromolecules.  16:214-218. 2015
2015 Structural insights into the stabilization of the human immunodeficiency virus type 1 capsid protein by the cyclophilin-binding domain and implications on the virus cycleBBA - Proteins and Proteomics.  1854:341-348. 2015
2014 The role of the coat protein A-domain in P22 bacteriophage maturationViruses.  6:2708-2722. 2014
2014 Charge detection mass spectrometry of bacteriophage P22 procapsid distributions above 20 MDaRapid Communications in Mass Spectrometry.  28:483-488. 2014
2014 Formation mechanism of chalcogenide nanocrystals confined inside genetically engineered virus-like particlesScientific Reports.  4. 2014
2014 Higher-order structure of the rous sarcoma virus SP assembly domainJournal of Virology.  88:5617-5629. 2014
2013 φ29 Scaffolding and connector structure-function relationship studied by trans-complementationVirology.  444:355-362. 2013
2013 Stabilizing viral nano-reactors for nerve-agent degradationBiomaterials Science.  1:881-886. 2013
2013 Structural and functional characterization of the mumps virus phosphoproteinJournal of Virology.  87:7558-7568. 2013
2013 Gap2 promotes the formation of a stable protein complex required for mature Fap1 biogenesisJournal of Bacteriology.  195:2166-2176. 2013
2013 Engineering nanocages with polyglutamate domains for coupling to hydroxyapatite biomaterials and allograft boneBiomaterials.  34:2455-2462. 2013
2013 Directed self-assembly of CdS quantum dots on bacteriophage P22 coat protein templatesNanotechnology.  24. 2013
2012 Coconfinement of fluorescent proteins: Spatially enforced communication of GFP and mCherry encapsulated within the P22 capsidBiomacromolecules.  13:3902-3907. 2012
2012 Virus-like particle nanoreactors: Programmed encapsulation of the thermostable CelB glycosidase inside the P22 capsidSoft Matter.  8:10158-10166. 2012
2012 Use of the interior cavity of the P22 capsid for site-specific initiation of atom-transfer radical polymerization with high-density cargo loadingNature Chemistry.  4:781-788. 2012
2012 Nanoreactors by programmed enzyme encapsulation inside the capsid of the bacteriophage P22ACS Nano.  6:5000-5009. 2012
2012 Building the machines: Scaffolding protein functions during bacteriophage morphogenesisAdvances in Experimental Medicine and Biology.  726:325-350. 2012
2012 Site-directed coordination chemistry with P22 virus-like particlesLangmuir.  28:1998-2006. 2012
2011 Materials design using genetically engineered proteinsJournal of Materials Chemistry.  21:18868-18876. 2011
2011 Genetically programmed in vivo packaging of protein cargo and its controlled release from bacteriophage P22Angewandte Chemie.  50:7425-7428. 2011
2011 A retroviral chimeric capsid protein reveals the role of the N-terminal β-hairpin in mature core assembly.Journal of Molecular Biology.  410:641-652. 2011
2011 New approaches for antiviral targeting of HIV assembly.Journal of Molecular Biology.  410:634-640. 2011
2011 Templated assembly of organic-inorganic materials using the core shell structure of the P22 bacteriophageChemical Communications.  47:6326-6328. 2011
2011 Three-dimensional structure of a viral genome-delivery portal vertexNature Structural Biology.  18:597-603. 2011
2010 Fabrication of ordered nanostructures of sulfide nanocrystal assemblies over self-assembled genetically engineered P22 coat proteinJournal of the American Chemical Society.  132:17354-17357. 2010
2010 Hydrogen/Deuterium Exchange Analysis of HIV-1 Capsid Assembly and MaturationStructure.  18:1483-1491. 2010
2010 Myristate exposure in the human immunodeficiency virus type 1 matrix protein is modulated by pHBiochemistry.  49:9551-9562. 2010
2010 Mind the gap: How some viruses infect their hostsViruses.  2:2536-2540. 2010
2010 Implementation of P22 viral capsids as nanoplatformsBiomacromolecules.  11:2804-2809. 2010
2010 Escherichia coli bacteria-templated synthesis of nanoporous cadmium sulfide hollow microrods for efficient photocatalytic hydrogen productionJournal of Physical Chemistry C.  114:2551-2559. 2010
2010 A docking model based on mass spectrometric and biochemical data describes phage packaging motor incorporationMolecular and Cellular Proteomics.  9:1764-1773. 2010
2010 Polymer-virus core-shell structures prepared via co-assembly and template synthesis methodsScience in China Series B: Chemistry.  53:71-77. 2010
2009 In vitro incorporation of the phage Phi29 connector complexVirology.  394:149-153. 2009
2009 Characterization of a mumps virus nucleocapsidlike particleJournal of Virology.  83:11402-11406. 2009
2009 Synthesis of biotin-tagged chemical cross-linkers and their applications for mass spectrometryRapid Communications in Mass Spectrometry.  23:1719-1726. 2009
2009 The P22 Tail Machine at Subnanometer Resolution Reveals the Architecture of an Infection ConduitStructure.  17:789-799. 2009
2008 Controlled assembly of bifunctional chimeric protein cages and composition analysis using noncovalent mass spectrometryJournal of the American Chemical Society.  130:16527-16529. 2008
2008 Detection of Intermediates and Kinetic Control during Assembly of Bacteriophage P22 ProcapsidJournal of Molecular Biology.  381:1395-1406. 2008
2008 Send for reinforcements! Conserved binding of capsid decoration proteins.Structure.  16:1292-1293. 2008
2008 Probing Conserved Helical Modules of Portal Complexes by Mass Spectrometry-based Hydrogen/Deuterium ExchangeJournal of Molecular Biology.  381:772-784. 2008
2008 Hydrogen/deuterium exchange on protein solutions containing nucleic acids: Utility of protamine sulfateRapid Communications in Mass Spectrometry.  22:2423-2428. 2008
2008 Development of bacteriophage P22 a platform for molecular display: Genetic and chemical modifications of the procapsid exterior surfaceChemBioChem.  9:514-518. 2008
2008 Incorporation of scaffolding protein gpO in bacteriophages P2 and P4Virology.  370:352-361. 2008
2007 Subunit conformations and assembly states of a DNA-translocating motor: the terminase of bacteriophage P22.Journal of Molecular Biology.  374:817-836. 2007
2007 An aggregation-prone intermediate species is present in the unfolding pathway of the monomeric portal protein of bacteriophage P22: Implications for portal assemblyBiochemistry.  46:7353-7364. 2007
2007 Molecular Dissection of Ø29 Scaffolding Protein Function in an in Vitro Assembly SystemJournal of Molecular Biology.  366:1161-1173. 2007
2007 Macromolecular mass spectrometry and electron microscopy as complementary tools for investigation of the heterogeneity of bacteriophage portal assembliesJournal of ultrastructure research.  157:371-383. 2007
2006 Dynamic motions of free and bound Ø29 scaffolding protein identified by hydrogen deuterium exchange mass spectrometryProtein Science.  15:731-743. 2006
2006 Identification of subunit-subunit interactions in bacteriophage P22 procapsids by chemical cross-linking and mass spectrometry.Journal of Proteome Research.  5:370-377. 2006
2005 Three-dimensional structure of the bacteriophage P22 tail machineEMBO Journal.  24:2087-2095. 2005
2005 In vitro assembly of bacteriophages: Folding, kinetic control and intermediatesJournal of Theoretical Medicine.  6:139. 2005
2005 Domain study of bacteriophage p22 coat protein and characterization of the capsid lattice transformation by hydrogen/deuterium exchange.Journal of Molecular Biology.  347:935-948. 2005
2005 Kinetic and mass spectrometry-based investigation of human immunodeficiency virus type 1 assembly and maturation.Advances in Virus Research.  64:285-309. 2005
2004 Investigation of N-terminal domain charged residues on the assembly and stability of HIV-1 CA.Biochemistry.  43:10435-10441. 2004
2004 Key interactions in HIV-1 maturation identified by hydrogen-deuterium exchange.Nature Structural Biology.  11:676-677. 2004
2004 High-sensitivity mass spectrometry for imaging subunit interactions: hydrogen/deuterium exchange.Current Opinion in Structural Biology.  14:181-188. 2004
2003 Coat protein fold and maturation transition of bacteriophage P22 seen at subnanometer resolutionsNature Structural Biology.  10:131-135. 2003
2003 Identification of novel interactions in HIV-1 capsid protein assembly by high-resolution mass spectrometryJournal of Molecular Biology.  325:759-772. 2003
2003 Mechanism of scaffolding-assisted viral assembly.Advances in Protein Chemistry.  64:259-299. 2003
2003 Viral genome organization.Advances in Protein Chemistry.  64:219-258. 2003
2002 Mapping of protein:protein contact surfaces by hydrogen/deuterium exchange, followed by on-line high-performance liquid chromatography-electrospray ionization fourier-transform ion-cyclotron-resonance mass analysisChromatographic reviews.  982:85-95. 2002
2002 Preliminary crystallographic analysis of the bacteriophage P22 portal proteinJournal of ultrastructure research.  139:46-54. 2002
2002 A P22 scaffold protein mutation increases the robustness of head assembly in the presence of excess portal protein.Journal of Virology.  76:10245-10255. 2002
2002 Kinetic analysis of the role of intersubunit interactions in human immunodeficiency virus type 1 capsid protein assembly in vitro.Journal of Virology.  76:6900-6908. 2002
2002 DNA packaging: A new class of molecular motorsCurrent Biology.  12:R96-R98. 2002
2002 Bacteriophage p22 portal vertex formation in vivoJournal of Molecular Biology.  315:975-994. 2002
2001 Structure of bacteriophage P22 portal protein in relation to assembly: Investigation by Raman spectroscopyBiochemistry.  40:13583-13591. 2001
2001 Kinetic and calorimetric evidence for two distinct scaffolding protein binding populations within the bacteriophage P22 procapsidBiochemistry.  40:8962-8970. 2001
2001 Structural Transformations Accompanying the Assembly of Bacteriophage P22 Portal Protein Rings in VitroJournal of Biological Chemistry.  276:6779-6788. 2001
2001 Hydrogen-deuterium exchange as a probe of folding and assembly in viral capsidsJournal of Molecular Biology.  306:389-396. 2001
2001 Characterization of subunit structural changes accompanying assembly of the bacteriophage P22 procapsid.Biochemistry.  40:665-674. 2001
2000 Structure of the coat protein-binding domain of the scaffolding protein from a double-stranded DNA virusJournal of Molecular Biology.  297:1195-1202. 2000
2000 Identification of additional coat-scaffolding interactions in a bacteriophage P22 mutant defective in maturationJournal of Virology.  74:3871-3873. 2000
2000 Visualization of the maturation transition in bacteriophage P22 by electron cryomicroscopyJournal of Molecular Biology.  297:615-626. 2000
1999 Identification and characterization of the domain structure of bacteriophage P22 coat protein.Biochemistry.  38:14614-14623. 1999
1999 Cavity defects in the procapsid of bacteriophage P22 and the mechanism of capsid maturation.Journal of Molecular Biology.  287:527-538. 1999
1999 Mechanism of scaffolding-directed virus assembly suggested by comparison of scaffolding-containing and scaffolding-lacking P22 procapsidsBiophysical Journal.  76:3267-3277. 1999
1999 Solution x-ray scattering-based estimation of electron cryomicroscopy imaging parameters for reconstruction of virus particlesBiophysical Journal.  76:2249-2261. 1999
1998 Local rules simulation of the kinetics of virus capsid self-assembly.Biophysical Journal.  75:2626-2636. 1998
1998 Electrostatic interactions drive scaffolding/coat protein binding and procapsid maturation in bacteriophage P22.Virology.  250:337-349. 1998
1998 Mechanism of capsid maturation in a double-stranded DNA virus.Proceedings of the National Academy of Sciences.  95:9885-9890. 1998
1998 A helical coat protein recognition domain of the bacteriophage P22 scaffolding proteinJournal of Molecular Biology.  281:81-94. 1998
1998 Functional domains of bacteriophage P22 scaffolding protein.Journal of Molecular Biology.  281:69-79. 1998
1998 Inhibiting virus-capsid assembly by altering the polymerisation pathway.Trends in Biotechnology.  16:61-65. 1998
1997 Bacteriophage P22 scaffolding protein forms oligomers in solution.Journal of Molecular Biology.  268:655-665. 1997
1997 Cloning, purification, and preliminary characterization by circular dichroism and NMR of a carboxyl-terminal domain of the bacteriophage p22 scaffolding proteinProtein Science.  6:1583-1586. 1997
1996 Three-dimensional structure of scaffolding-containing phage P22 procapsids by electron cryo-microscopyJournal of Molecular Biology.  260:85-98. 1996
1996 Structural transitions in the scaffolding and coat proteins of P22 virus during assembly and disassembly.Biochemistry.  35:4619-4627. 1996
1996 The use of hydrostatic pressure as a tool to study viruses and other macromolecular assemblagesCurrent Opinion in Structural Biology.  6:166-175. 1996
1995 New high sensitivity sedimentation methods: Application to the analysis of the assembly of bacteriophage P22Techniques in Protein Chemistry.  6:427-432. 1995
1995 Role of Entropic Interactions in Viral Capsids: Single Amino Acid Substitutions in P22 Bacteriophage Coat Protein Resulting in Loss of Capsid StabilityBiochemistry.  34:1120-1126. 1995
1994 Pressure denaturation of the bacteriophage P22 coat protein and its entropic stabilization in icosahedral shellsBiophysical Journal.  66:1631-1641. 1994
1993 Assembly of bacteriophage P22: a model for ds-DNA virus assembly.Progress in medical virology. Fortschritte der medizinischen Virusforschung. Progres en virologie medicale.  40:206-221. 1993
1993 Inhibition of Viral Capsid Assembly by 1,1′-Bi(4-anilinonaphthalene-5-sulfonic Acid)Biochemistry.  32:10658-10665. 1993
1993 Nucleation and growth phases in the polymerization of coat and scaffolding subunits into icosahedral procapsid shellsBiophysical Journal.  64:824-835. 1993
1993 Subunit Conformational Changes Accompanying Bacteriophage P22 Capsid MaturationBiochemistry.  32:537-543. 1993
1993 Three-dimensional transformation of capsids associated with genome packaging in a bacterial virusJournal of Molecular Biology.  231:65-74. 1993
1990 Conformational States of the Bacteriophage P22 Capsid Subunit in Relation to Self-AssemblyBiochemistry.  29:5626-5633. 1990
1988 Scaffolding protein regulates the polymerization of P22 coat subunits into icosahedral shells in vitro.Journal of Molecular Biology.  202:743-757. 1988
1987 Structural Studies of Acetylated and Control Inner Core HistonesBiochemistry.  26:2944-2955. 1987
1983 Studies on synthetic chromatins containing poly(dA-dT) X poly(dA-dT) and poly(dG-dC) X poly(dG-dC).BBA - Biochimica et Biophysica Acta.  739:85-96. 1983

Chapter

Year Title Altmetric
2010 Investigating viral structure, function and dynamics with mass spectrometry.  103-130. 2010

Education And Training

  • Doctor of Philosophy in Biochemistry, Brandeis University 1985
  • Full Name

  • Peter Prevelige