Positions

Selected Publications

Academic Article

Year Title Altmetric
2016 Accuracy of urinary human papillomavirus testing for the presence of cervical human papillomaviruses and higher grades of cervical intraepithelial neoplasiaCancer.  122:2836-2844. 2016
2016 An examination of racial differences in 5-year survival of cervical cancer among African American and white American women in the southeastern US from 1985 to 2010Cancer Medicine.  5:2126-2135. 2016
2016 Cervical microbiota associated with higher grade cervical intraepithelial neoplasia in women infected with high-risk human papillomavirusesCancer Prevention Research.  9:357-366. 2016
2016 Homocysteinemia is Associated with a Lower Degree of PBMC LINE-1 Methylation and a Higher Risk of CIN 2C in the U.S. Post-Folic Acid Fortification EraNutrition and Cancer.  68:446-455. 2016
2014 Functional variants in CYP1A1 and GSTM1 are associated with clearance of cervical HPV infectionGynecologic Oncology.  135:560-564. 2014
2014 A lower degree of PBMC L1 methylation in women with lower folate status may explain the MTHFR C677T polymorphism associated higher risk of CIN in the US post folic acid fortification eraPLoS ONE.  9. 2014
2014 Functional variants in CYP1A1 and GSTM1 are associated with clearance of cervical HPV infectionGynecologic Oncology2014
2014 Excess body weight during pregnancy and offspring obesity: Potential mechanismsNutrition.  30:245-251. 2014
2014 Excess body weight during pregnancy and offspring obesity: potential mechanisms.Nutrition.  30:245-251. 2014
2014 Folate and vitamin B12 may play a critical role in lowering the HPV 16 methylation - Associated risk of developing higher grades of CINCancer Prevention Research.  7:1128-1137. 2014
2013 Determinants of neural tube defect (NTD)-protective circulating concentrations of folate in women of child-bearing age in the US post-folic acid fortification eraNutrition Research and Practice.  7:315-325. 2013
2013 A Lower Degree of PBMC L1 Methylation Is Associated with Excess Body Weight and Higher HOMA-IR in the Presence of Lower Concentrations of Plasma FolatePLoS ONE.  8. 2013
2012 A dietary pattern associated with LINE-1 methylation alters the risk of developing cervical intraepithelial neoplasiaCancer Prevention Research.  5:385-392. 2012
2011 Usefulness of serum mass spectrometry to identify women diagnosed with higher grades of cervical intraepithelial neoplasia may differ by raceInternational Journal of Women's Health.  3:185-192. 2011
2011 A higher degree of LINE-1 methylation in peripheral blood mononuclear cells, a one-carbon nutrient related epigenetic alteration, is associated with a lower risk of developing cervical intraepithelial neoplasiaNutrition.  27:513-519. 2011
2011 Predictors and Health Consequences of Epigenetic Changes Associated with Excess Body Weight in Women of Child-bearing AgeCancer Epidemiology, Biomarkers and Prevention.  20:719-719. 2011
2011 A higher degree of methylation of the HPV 16 E6 gene is associated with a lower likelihood of being diagnosed with cervical intraepithelial neoplasiaCancer.  117:957-963. 2011
2010 Aflatoxin B 1 albumin adducts in plasma and aflatoxin M 1 in urine are associated with plasma concentrations of vitamins A and EInternational Journal for Vitamin and Nutrition Research.  80:355-368. 2010
2010 Indian women with higher serum concentrations of folate and vitamin B12 are significantly less likely to be infected with carcinogenic or high-risk (HR) types of human papillomaviruses (HPVs)International Journal of Women's Health.  2:7-12. 2010
2010 Association of genomewide newborn DNA methylation patterns with maternal and newborn characteristicsBMC Bioinformatics.  11:O4-O4. 2010
2009 Mandatory fortification with folic acid in the United States appears to have adverse effects on histone methylation in women with pre-cancer but not in women free of pre-cancerInternational Journal of Women's Health.  1:131-137. 2009
2009 Diet and deprivation in pregnancyBritish Journal of Nutrition.  102:1487-1497. 2009
2009 Diet and deprivation in pregnancyBritish Journal of Nutrition.  102:1487-1497. 2009
2009 Lower risk of cervical intraepithelial neoplasia in women with high plasma folate and sufficient vitamin B12 in the post-folic acid fortification era (Cancer Prevention Research (2009) 2, (658-664))Cancer Prevention Research.  2:842. 2009
2009 Lower risk of cervical intraepithelial neoplasia in women with high plasma folate and sufficient vitamin B12 in the post-folic acid fortification eraCancer Prevention Research.  2:658-664. 2009
2008 Mandatory fortification with folic acid in the United States is associated with increased expression of DNA methyltransferase-1 in the cervixNutrition.  24:94-99. 2008
2007 A practical approach to red blood cell folate analysis.Analytical Chemistry Insights.  2:107-110. 2007
2007 Lower red blood cell folate enhances the HPV-16-associated risk of cervical intraepithelial neoplasiaNutrition.  23:203-210. 2007
2007 Protective association of MTHFR polymorphism on cervical intraepithelial neoplasia is modified by riboflavin statusNutrition.  23:229-235. 2007
2007 Update on micronutrients and cervical dysplasiaEthnicity and Disease.  17. 2007
2007 Plasma protein profiles differ between women diagnosed with cervical intraepithelial neoplasia (cin) 1 and 3.Cancer Informatics.  2:345-349. 2007
2007 Update on micronutrients and cervical dysplasia.Ethnicity and Disease.  17:S2-14-7. 2007
2006 Plasma protein profiles differ between women diagnosed with cervical intraepithelial neoplasia (CIN) 1 and 3Cancer Informatics.  2:421-425. 2006
2006 Intrinsic cisplatin resistance in lung and ovarian cancer cells propagating in medium acutely depleted of folateNutrition and Cancer.  54:274-284. 2006
2006 Effect of short-term, high-dose retinol on dark adaptation in aging and early age-related maculopathyInvestigative Ophthalmology & Visual Science.  47:1310-1318. 2006
2006 The mandatory fortification of foods with folic acid in the United States is not associated. with an improvement in the degree or pattern of global DNA methylation in the cervical epitheliumFederation proceedings.  20:A600-A600. 2006
2006 Mandatory fortification with folic acid in the United States is not associated with changes in the degree or the pattern of global DNA methylation in cells involved in cervical carcinogenesisCancer Biomarkers.  2:259-266. 2006
2005 Pattern of nonspecific (or global) DNA methylation in oral carcinogenesisHead & neck surgery.  27:1061-1067. 2005
2005 Patterns of global DNA and histone methylation appear to be similar in normal, dysplastic and neoplastic oral epithelium of humansDisease Markers.  21:147-151. 2005
2004 Folate is associated with the natural history of high-risk human papillomavirusesCancer Research.  64:8788-8793. 2004
2003 Beta-carotene is most predictive of fruit and vegetable intake in an all-female population of smokersFederation proceedings.  17:A711-A711. 2003
2003 Folate is associated with the acquisition, persistence and clearance of high-risk (HR) human papillomavirus (HPV)Federation proceedings.  17:A373-A373. 2003
2003 Methylenetetrahydrofolate reductase (MTHFR) and methionine synthase (MS) polymorphisms are associated with a decreased risk of cervical dysplasiaFederation proceedings.  17:A373-A373. 2003
2003 Race- and age-dependent alterations in global methylation of DNA in squamous cell carcinoma of the lung (United States)Cancer Causes and Control.  14:37-42. 2003
2003 Nuclear accumulation of p53 is a potential marker for the development of squamous cell lung cancer in smokersChest.  123:181-186. 2003
2003 Receiver operating characteristic (ROC) to determine cut-off points of biomarkers in lung cancer patientsDisease Markers.  19:273-278. 2003
2002 DNA methylation and diet in cancerJournal of Nutrition.  132. 2002
2002 The pattern of expression of Mn and Cu-Zn superoxide dismutase varies among squamous cell cancers of the lung, larynx, and oral cavityHead & neck surgery.  24:859-867. 2002
2002 Cellular vitamins, DNA methylation and cancer riskJournal of Nutrition.  132:2340S-2344S. 2002
2002 Cellular vitamins, DNA methylation and cancer risk.Journal of Nutrition.  132:2340S-2344S. 2002
2002 Differential expression of growth factors in squamous cell carcinoma and precancerous lesions of the lungClinical Cancer Research.  8:734-744. 2002
2001 Modulation of cancer risk by genetic polymorphism of methylene tetrahydrofolate reductase (MTHFR) and methionine synthase (MS) may depend on the racial distribution of study subjects.Federation proceedings.  15:A618-A618. 2001
2001 Nuclear accumulation of p53 is a potential marker for the development of squamous cell lung cancer in smokers.Federation proceedings.  15:A249-A249. 2001
2001 Race and age-dependent alterations in global methylation of DNA in squamous cell carcinoma of the lung.Federation proceedings.  15:A618-A618. 2001
2001 Variations of vitamin concentrations and DNA methylation in squamous cell cancers of the oral cavity, larynx and lung.Federation proceedings.  15:A619-A619. 2001
2001 Altered global methylation of DNA: An epigenetic difference in susceptibility for lung cancer is associated with its progressionHuman Pathology.  32:856-862. 2001
2000 The accumulation of ascorbic acid by squamous cell carcinomas of the lung and larynx is associated with global methylation of DNACancer.  89:171-176. 2000
2000 Methylenetetrahydrofolate reductase (MTHFR) polymorphism increases the risk of cervical intraepithelial neoplasia.Anticancer Research.  20:1751-1757. 2000
2000 The accumulation of ascorbic acid by squamous cat cancers of the lung, larynx and oral cavity.Federation proceedings.  14:A232-A232. 2000
2000 Immunohistochemical evaluation of global DNA methylation: Comparison with in vitro radiolabeled methyl incorporation assayStain technology.  75:251-258. 2000
2000 The expression of Ep-CAM (17-1A) in squamous cell cancers of the lungHuman Pathology.  31:482-487. 2000
2000 The expression of fatty acid synthase (FASE) is an early event in the development and progression of squamous cell carcinoma of the lungHuman Pathology.  31:1068-1073. 2000
1994 LOCAL AND SYSTEMIC EFFECTS OF CIGARETTE-SMOKING ON FOLATE AND VITAMIN-B-12Federation proceedings.  8:A717-A717. 1994
1994 Local and systemic effects of cigarette smoking on folate and vitamin B- 12American Journal of Clinical Nutrition.  60:559-566. 1994
1993 EFFECT OF SMOKING ON BUCCAL MUCOSAL VITAMIN-B12 LEVELSFederation proceedings.  7:A743-A743. 1993
1992 EVIDENCE OF FREE, BOUND AND POLYGLUTAMATE FORMS OF FOLATE IN HUMAN SALIVAFederation proceedings.  6:A1372-A1372. 1992
1992 Effect of smoking on folate levels in buccal mucosal cellsInternational Journal of Cancer.  52:566-569. 1992

Education And Training

  • Doctor of Philosophy in Nutrition Sciences, University of Alabama at Birmingham 1993
  • Master of Public Health in International Public Health / International Health, University of Alabama at Birmingham 1988
  • Doctor of Dental Science in Dentistry, University of Peradeniya 1981
  • Full Name

  • Chandrika Piyathilake