Selected Publications

Academic Article

Year Title Altmetric
2022 Comparative pharmacokinetics and tissue distribution of primaquine enantiomers in miceMalaria Journal.  21. 2022
2022 Herb-drug interactions in neuropsychiatric pharmacotherapy-a review of clinically relevant findingsCurrent Neuropharmacology.  20:1736-1751. 2022
2022 Rare Heterogeneous Adverse Events Associated with mRNA-Based COVID-19 Vaccines: A Systematic Review.Medicines.  9. 2022
2022 Comparative single dose pharmacokinetics and metabolism of racemic primaquine and its enantiomers in human volunteersDrug Metabolism and Pharmacokinetics.  45. 2022
2022 Editorial: Fungal Bioactive Metabolites of Pharmacological RelevanceFrontiers in Pharmacology.  13. 2022
2021 Traditional medicines for COVID-19: Perspectives from clinical pharmacologistsBritish Journal of Clinical Pharmacology.  87:3455-3458. 2021
2021 Clinical management of covid-19: A review of pharmacological treatment optionsPharmaceuticals.  14. 2021
2021 Sexually Transmitted Neisseria gonorrhoeae Infections-Update on Drug Treatment and Vaccine Development.Medicines.  8. 2021
2021 Quantitative determination of primaquine-5,6-ortho-quinone and carboxyprimaquine-5,6-ortho-quinone in human erythrocytes by UHPLC-MS/MS 2021
2021 Assessment and clinical utility of pharmacogenomics by healthcare practitioners in North CarolinaPharmacogenomics.  22:13-25. 2021
2020 Antiprotozoal investigation of three Combretum species (Combretaceae) growing in NigeriaHerba Polonica.  65:37-44. 2020
2020 Pitolisant and Other Histamine-3 Receptor Antagonists-An Update on Therapeutic Potentials and Clinical Prospects.Medicines.  7. 2020
2019 Herbal Interaction With Chemotherapeutic Drugs—A Focus on Clinically Significant FindingsFrontiers in Oncology.  9. 2019
2019 Plasmodium vivax chloroquine resistance links to pvcrt transcription in a genetic crossNature Communications.  10. 2019
2019 Direct-Acting Oral Anticoagulants and Their Reversal Agents-An Update.Medicines.  6. 2019
2019 Wild vegetable Rumex acetosa Linn.: Its ethnobotany, pharmacology and phytochemistry – A reviewSouth African Journal of Botany.  125:149-160. 2019
2019 Formation primaquine-5,6-orthoquinone, the putative active and toxic metabolite of primaquine via direct oxidation in human erythrocytesMalaria Journal.  18. 2019
2018 Metabolism of primaquine in normal human volunteers: Investigation of phase i and phase II metabolites from plasma and urine using ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometryMalaria Journal.  17. 2018
2018 Antimicrobial and antiprotozoal activities of twenty-four Nigerian medicinal plant extractsSouth African Journal of Botany.  117:240-246. 2018
2018 Antiplasmodial and acute toxicity studies of fractions and cassane-type diterpenoids from the stem bark of Caesalpinia pulcherrima (L.) Sw. 2018
2018 Antiprotozoal, antiviral and cytotoxic properties of the Nigerian mushroom, hypoxylon fuscum pers. Fr. (xylariaceae)Acta Pharmaceutica Sciencia.  56:43-56. 2018
2018 Evaluation of selected Nigerian medicinal plants for in vitro antiprotozoal activityNatural Products Journal.  8:175-184. 2018
2017 Modulation of cytochrome P450, P-glycoprotein and pregnane x receptor by selected antimalarial herbs—implication for herb-drug interactionMolecules.  22. 2017
2017 Assessment of selected medicinal plants indigenous to West Africa for antiprotozoal activitySouth African Journal of Botany.  113:200-211. 2017
2017 Antiprotozoal and cytotoxicity studies of fractions and compounds from enantia chlorantha 2017
2017 Pyrenacantha staudtii hutch and dalz (Icacinaceae): A review of phytochemistry, pharmacology and future perspectives 2017
2017 Enhancement of the Oral Bioavailability of Felodipine Employing 8-Arm-Poly(Ethylene Glycol): In Vivo, In Vitro and In Silico EvaluationAAPS PharmSciTech.  18:617-628. 2017
2016 Phenotyping and genotyping of CYP2C19 using comparative metabolism of proguanil in sickle-cell disease patients and healthy controls in Nigeria 2016
2016 Pathway-specific inhibition of primaquine metabolism by chloroquine/quinineMalaria Journal.  15. 2016
2016 Current Status and Prospects for Cannabidiol Preparations as New Therapeutic Agents 2016
2016 Antimalarial and cytotoxic properties of Chukrasia tabularis A. Juss and Turraea vogelii Hook F. Ex. BenthParasitology Research.  115:1667-1674. 2016
2016 Clinically relevant pharmacokinetic herb-drug interactions in antiretroviral therapyCurrent Drug Metabolism.  17:52-64. 2016
2016 Differential kinetic profiles and metabolism of primaquine enantiomers by human hepatocytesMalaria Journal.  15. 2016
2016 High cadmium levels in cured meat products marketed in Nigeria - implications for public health 2016
2015 Enantioselective pharmacokinetics of Primaquine in healthy human volunteersDrug Metabolism and Disposition.  43:571-577. 2015
2014 Application of Caco-2 cell line in herb-drug interaction studies: Current approaches and challengesJournal of Pharmacy and Pharmaceutical Sciences.  17. 2014
2014 Enantioselective metabolism of primaquine by human CYP2D6Malaria Journal.  13. 2014
2014 The inhibitory activity of the extracts of popular medicinal herbs on CYP1A2, 2C9, 2C19 and 3A4 and the implications for herb-drug interaction 2014
2013 The potential of Hypoxis hemerocallidea for herb-drug interactionPharmaceutical Biology.  51:1499-1507. 2013
2013 Comparative evaluation of warfarin utilisation in two primary healthcare clinics in the Cape Town area 2013
2013 The potential of sutherlandia frutescens for herb-drug interactionDrug Metabolism and Disposition.  41:488-497. 2013
2013 Flavonoids and polymer derivatives as CYP3A4 inhibitors for improved oral drug bioavailabilityJournal of Pharmaceutical Sciences.  102:541-555. 2013
2013 Heavy metal pollution in sub-saharan africa and possible implications in cancer epidemiology 2013
2012 An overview of the evidence and mechanisms of herb-drug interactionsFrontiers in Pharmacology.  3 APR. 2012
2012 Liver-based in vitro technologies for drug biotransformation studies - A reviewCurrent Drug Metabolism.  13:215-224. 2012
2011 Diverse approaches for the enhancement of oral drug bioavailabilityBiopharmaceutics and Drug Disposition.  32:185-209. 2011


Year Title Altmetric
2019 Nutrition and cancer - An update on the roles of dietary factors in the etiology, progression and management of cancer.  703-714. 2019

Education And Training

  • Doctor of Philosophy Level Degree in Pharmacology, Stellenbosch University 2013
  • Full Name

  • Pius Fasinu