Positions

Selected Publications

Academic Article

Year Title Altmetric
2018 Cytomegalovirus promotes intestinal macrophage-mediated mucosal inflammation through induction of Smad7Mucosal Immunology.  11:1694-1704. 2018
2018 CD103 (αE Integrin) Undergoes Endosomal Trafficking in Human Dendritic Cells, but Does Not Mediate Epithelial AdhesionFrontiers in Immunology.  9:2989. 2018
2017 Helicobacter pylori infection is associated with an altered gastric microbiota in childrenMucosal Immunology.  10:1169-1177. 2017
2017 Characterization of human blood monocytes and intestinal macrophagesCurrent protocols in immunology / edited by John E. Coligan ... [et al.].  2017:14.3.1-14.3.14. 2017
2017 Differential regulation of CD103 (αE integrin) expression in human dendritic cells by retinoic acid and Toll-like receptor ligandsJournal of Leukocyte Biology.  101:1169-1180. 2017
2017 CD4 regulatory T cells augment HIV-1 expression of polarized M1 and M2 monocyte derived macrophagesVirology.  504:79-87. 2017
2016 Elucidating the Role of the Interleukin-10 Receptor in Mucosal Inflammation Uncovers a Potential Treatment for Infantile Inflammatory Bowel DiseaseGastroenterology.  151:1061-1062. 2016
2015 Mother-to-child HIV-1 transmission events are differentially impacted by breast milk and its components from HIV-1-infected womenPLoS ONE.  10. 2015
2015 Bioenergetic programming of macrophages by the apolipoprotein A-I mimetic peptide 4FBiochemical Journal.  467:517-527. 2015
2015 Human gastric epithelial cells contribute to gastric immune regulation by providing retinoic acid to dendritic cellsMucosal Immunology.  8:533-544. 2015
2014 Microbiota, the immune system, black moods and the brain—melancholia updatedFrontiers in Human Neuroscience.  8:1-4. 2014
2014 Differential glycosylation of envelope gp120 is associated with differential recognition of HIV-1 by virus-specific antibodies and cell infectionAIDS Research and Therapy.  11. 2014
2014 Brain angiogenesis inhibitor 1 is expressed by gastric phagocytes during infection with Helicobacter pylori and mediates the recognition and engulfment of human apoptotic gastric epithelial cellsFederation proceedings.  28:2214-2224. 2014
2014 Cytomegalovirus enhances macrophage TLR expression and MyD88-mediated signal transduction to potentiate inducible inflammatory responsesJournal of Immunology.  193:5604-5612. 2014
2014 Exosomes in the gutFrontiers in Immunology.  5. 2014
2014 Gastric microbiome and gastric cancerCancer Journal.  20:211-216. 2014
2014 HIV-1 envelope glycan moieties modulate HIV-1 transmissionJournal of Virology.  88:14258-14267. 2014
2014 Interactions between HIV-1 and Mucosal Cells in the Female Reproductive TractAmerican Journal of Reproductive Immunology.  71:608-617. 2014
2014 Interactions between HIV-1 and Mucosal Cells in the Female Reproductive TractAmerican Journal of Reproductive Immunology.  71:606-17. 2014
2014 Mucosal correlates of protection in HIV-1-exposed sero-negative personsAmerican Journal of Reproductive Immunology.  72:219-227. 2014
2014 Vaginal myeloid dendritic cells transmit founder HIV-1Journal of Virology.  88:7683-7688. 2014
2013 Role of childhood infection in the sequelae of H. Pylori diseaseGut Microbes.  4. 2013
2013 Downregulated Th17 responses are associated with reduced gastritis in Helicobacter pylori-infected childrenMucosal Immunology.  6:950-959. 2013
2013 Helicobacter pylori infection inhibits phagocyte clearance of apoptotic gastric epithelial cellsJournal of Immunology.  190:6626-6634. 2013
2013 Nucleotide-binding oligomerization domain 2 signaling promotes hyperresponsive macrophages and colitis in IL-10-deficient miceJournal of Immunology.  190:2948-2958. 2013
2013 Renal macrophages in autosomal recessive polycystic kidney diseaseNephrology.  18:746. 2013
2012 Regulation of pattern recognition receptors by the apolipoprotein A-I mimetic peptide 4FArteriosclerosis, Thrombosis, and Vascular Biology.  32:2631-2639. 2012
2012 Chronic rectal bleeding due to lymphogranuloma venereum proctocolitisAmerican Journal of Gastroenterology.  107:488-489. 2012
2011 Extracellular matrix-associated cytokines regulate CD4+ effector T-cell responses in the human intestinal mucosaMucosal Immunology.  4:420-427. 2011
2011 Stromal down-regulation of macrophage CD4/CCR5 expression and NF-κB activation mediates HIV-1 non-permissiveness in intestinal macrophagesPLoS Pathogens.  7. 2011
2011 Impaired basophil induction leads to an age-dependent innate defect in type 2 immunity during helminth infection in miceJournal of Immunology.  186:4631-4639. 2011
2011 Early HIV-1 Target Cells in Human Vaginal and Ectocervical MucosaAmerican Journal of Reproductive Immunology.  65:261-267. 2011
2011 Intestinal macrophages and response to microbial encroachmentMucosal Immunology.  4:31-42. 2011
2011 Stromal regulation of human gastric dendritic cells restricts the Th1 response to helicobacter pyloriGastroenterology.  141:929-938. 2011
2010 Glycosylation patterns of HIV-1 gp120 depend on the type of expressing cells and affect antibody recognitionJournal of Biological Chemistry.  285:20860-20869. 2010
2010 Inflammation anergy in human intestinal macrophages is due to Smad-induced IκBα expression and NF-κB inactivationJournal of Biological Chemistry.  285:19593-19604. 2010
2010 Apolipoprotein A-I mimetic 4F alters the function of human monocyte-derived macrophagesAmerican Journal of Physiology - Cell Physiology.  298. 2010
2010 Human primary gastric dendritic cells induce a Th1 response to H. pyloriMucosal Immunology.  3:260-269. 2010
2010 Dendritic cells transmit HIV-1 through human small intestinal mucosaJournal of Leukocyte Biology.  87:663-670. 2010
2010 GP41-specific antibody blocks cell-free HIV type 1 transcytosis through human rectal mucosa and model colonic epitheliumJournal of Immunology.  184:3648-3655. 2010
2010 C-type lectin SIGN-R1 has a role in experimental colitis and responsiveness to lipopolysaccharideJournal of Immunology.  184:2627-2637. 2010
2010 C-type lectin SIGN-R1 has a role in experimental colitis and responsiveness to lipopolysaccharide (Journal of Immunology (2010) 184, (2627-2637))Journal of Immunology.  184. 2010
2010 IL-17 activates the canonical NF-κB signaling pathway in autoimmune B cells of BXD2 mice to upregulate the expression of regulators of G-protein signaling 16Journal of Immunology.  184:2289-2296. 2010
2010 Renal CD14 expression correlates with the progression of cystic kidney diseaseKidney International.  78:550-560. 2010
2009 Generation of parasite antigens for use in toll-like receptor researchMethods in Molecular Biology.  517:401-413. 2009
2009 Isolation of whole mononuclear Cells from peripheral blood and cord bloodCurrent protocols in immunology / edited by John E. Coligan ... [et al.]2009
2009 Macrophages in vaginal but not intestinal mucosa are monocyte-like and permissive to human immunodeficiency virus type 1 infectionJournal of Virology.  83:3258-3267. 2009
2009 Mucosal immunology of the genital and gastrointestinal tracts and HIV-1 infectionJournal of Reproductive Immunology.  83:196-200. 2009
2009 Selective advantage of inflammation anergy in gut macrophagesMucosal Immunology.  2:378-9. 2009
2009 The C-type lectin SIGNR1 binds Schistosoma mansoni antigens in vitro, but SIGNR1-deficient mice have normal responses during schistosome infectionInfection and Immunity.  77:399-404. 2009
2008 Effects of Lactobacillus salivarius 433118 on intestinal inflammation, immunity status and in vitro colon function in two mouse models of inflammatory bowel diseaseDigestive Diseases and Sciences.  53:2495-2506. 2008
2008 Helicobacter pylori Gastritis in Children Is Associated With a Regulatory T-Cell ResponseGastroenterology.  134:491-499. 2008
2007 Severe Gastrointestinal disease due to HIV-1-seronegative AIDSZeitschrift für Gastroenterologie.  45:706-709. 2007
2007 Infection with a helminth parasite prevents experimental colitis via a macrophage-mediated mechanismJournal of Immunology.  178:4557-4566. 2007
2007 Gliadin peptides activate blood monocytes from patients with celiac diseaseJournal of Clinical Immunology.  27:201-209. 2007
2006 Involvement of dendritic cells in the pathogenesis of inflammatory bowel diseaseAdvances in Experimental Medicine and Biology.  579:117-132. 2006
2006 Cytomegalovirus blocks intestinal stroma-induced down-regulation of macrophage HIV-1 infectionJournal of Leukocyte Biology.  80:1111-1117. 2006
2006 Mucosal IL-8 and TGF-β recruit blood monocytes: Evidence for cross-talk between the lamina propria stroma and myeloid cellsJournal of Leukocyte Biology.  80:492-499. 2006
2006 Isolation and purification of human intestinal macrophages.Current protocols in immunology / edited by John E. Coligan ... [et al.].  Chapter 7. 2006
2006 Isolation of human monocyte populations.Current protocols in immunology / edited by John E. Coligan ... [et al.].  Chapter 7. 2006
2005 Schistosoma mansoni secretes a chemokine binding protein with antiinflammatory activityJournal of Experimental Medicine.  202:1319-1325. 2005
2005 Intestinal macrophages: Unique effector cells of the innate immune systemImmunological Reviews.  206:149-159. 2005
2005 Poliovirus replicons encoding the B subunit of Helicobacter pylori urease protect mice against H. pylori infectionVaccine.  23:901-909. 2005
2005 Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activityJournal of Clinical Investigation.  115:66-75. 2005
2005 Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity.Journal of Clinical Investigation.  115:66-75. 2005
2004 Schistosoma mansoni worms induce anergy of T cells via selective up-regulation of programmed death ligand 1 on macrophagesJournal of Immunology.  173:1240-1248. 2004
2003 Macrophage HIV-1 infection and the gastrointestinal tract reservoirJournal of Leukocyte Biology.  74:642-649. 2003
2003 Cytomegalovirus production by infected astrocytes correlates with transforming growth factor-β releaseJournal of Infectious Diseases.  187:534-541. 2003
2002 Cytokine gene profile in gastric mucosa in Helicobacter pylori infection and Zollinger-Ellison syndromeAmerican Journal of Gastroenterology.  97:312-318. 2002
2002 Human cytomegalovirus enhances chemokine production by lipopolysaccharide-stimulated lamina propria macrophagesJournal of Infectious Diseases.  185:584-590. 2002
2002 Cytokine gene profile in gastric mucosa in Helicobacter pylori infection and Zollinger-Ellison syndrome.American Journal of Gastroenterology.  97:312-318. 2002
2002 Human cytomegalovirus primes lamina propria macrophages for enhanced LPS-stimulated chemokine productionJournal of Infectious Diseases.  185:584-90. 2002
2002 Primary intestinal epithelial cells selectively transfer R5 HIV-1 to CCR5+ cellsNature Medicine.  8:150-156. 2002
2001 Intestinal macrophages lack CD14 and CD89 and consequently are down-regulated for LPS- and IgA-mediated activitiesJournal of Immunology.  167:2651-2656. 2001
2001 MHC class I-related neonatal Fc receptor for IgG is functionally expressed in monocytes, intestinal macrophages, and dendritic cellsJournal of Immunology.  166:3266-3276. 2001
2001 Dissemination and pathology of simian immunodeficiency virus PBj14 early after rectal infection of pig-tailed macaquesJournal of Virology.  75:278-91. 2001
2001 Emerging concepts in gastrointestinal aspects of HIV-1 pathogenesis and managementGastroenterology.  120:607-621. 2001
2001 Emerging concepts in the pathophysiology and management of the gastrointestinal manifestations of AIDSGastroenterology.  120:607-21. 2001
2001 Isolation of whole mononuclear cells from peripheral blood and cord blood.Current protocols in immunology / edited by John E. Coligan ... [et al.].  Chapter 7. 2001
2001 Laser capture microdissection.Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.].  Chapter 25. 2001
2000 Biological parameters of HIV-1 infection in primary intestinal lymphocytes and macrophagesJournal of Leukocyte Biology.  68:360-365. 2000
2000 Quantitative analysis of Helicobacter pylori infection in a mouse modelJournal of Immunological Methods.  242:67-78. 2000
2000 Helicobacter pylori-induced mucosal inflammation is Th1 mediated and exacerbated in IL-4, but not IFN-γ, gene-deficient miceJournal of Immunology.  165:1022-1029. 2000
2000 Inflammatory cytokine mRNA expression during early and persistent Helicobacter pylori infection in nonhuman primatesJournal of Infectious Diseases.  181:783-786. 2000
2000 Lamina propria lymphocytes, not macrophages, express CCR5 and CXCR4 and are the likely target cell for human immunodeficiency virus type 1 in the intestinal mucosaJournal of Infectious Diseases.  182:785-791. 2000
1999 Poliovirus replicons encoding the B subunit of Helicobacter pylori urease elicit a Th1 associated immune responseVaccine.  17:2384-2391. 1999
1999 Mucosal events in the pathogenesis of human immunodeficiency virus type 1 infectionJournal of Infectious Diseases.  179. 1999
1999 Gastrointestinal infections in the immunocompromised hostCurrent Opinion in Gastroenterology.  15:85-89. 1999
1999 HIV-1 Infection, mucosal immunity and pathogenesis: Comments and conference summaryJournal of Infectious Diseases.  179:397-400. 1999
1999 Intestinal macrophages display reduced permissiveness to human immunodeficiency virus i and decreased surface CCR5Gastroenterology.  116:1043-1053. 1999
1999 No relationship between gastric pH, small bowel bacterial colonisation, and diarrhoea in HIV-1 infected patientsGut.  44:101-105. 1999
1998 African trypanosome infections in mice that lack the interferon-γ receptor gene: Nitric oxide-dependent and -independent suppression of T-cell proliferative responses and the development of anaemiaImmunology.  94:476-480. 1998
1998 Nitric oxide produced in the lungs of mice immunized with the radiation- attenuated schistosome vaccine is not the major agent causing challenge parasite eliminationImmunology.  93:55-63. 1998
1998 High mucosal levels of tumor necrosis factor α messenger RNA in AIDS- associated cytomegalovirus-induced esophagitisGastroenterology.  114:77-82. 1998
1998 Recombinant helicobactev pylori urease activates primary mucosal macrophagesJournal of Infectious Diseases.  178:1516-1520. 1998
1997 Isolation and purification of CD14-negative mucosal macrophages from normal human small intestineJournal of Immunological Methods.  202:1-11. 1997
1997 Age-related decline in murine macrophage production of nitric oxideJournal of Infectious Diseases.  175:1004-1007. 1997
1997 Infection of gastrointestinal tract macrophages by HIV-1Journal of Leukocyte Biology.  62:72-77. 1997
1997 Mucosal macrophages in infection and immunityMucosal Immunology Update.  5:32-4. 1997
1996 Helicobacter pylori cytotoxin induces vacuolation of primary human mucosal epithelial cellsInfection and Immunity.  64:4867-4871. 1996
1996 Gastrointestinal infections in the immunocompromised hostCurrent Opinion in Gastroenterology.  12:95-101. 1996
1996 Helicobacter pylori urease is a potent stimulus of mononuclear phagocyte activation and inflammatory cytokine productionGastroenterology.  111:419-425. 1996
1996 Immunobiology of mucosal HIV-1 infectionCurrent Opinion in Gastroenterology.  12:560-563. 1996
1996 Impaired immunity and altered pulmonary responses in mice with a disrupted interferon-γ receptor gene exposed to the irradiated Schistosoma mansoni vaccineImmunology.  87:275-282. 1996
1996 Kinetics and mechanism of effector focus formation in the lungs of mice vaccinated with irradiated cercariae of Schistosoma mansoniParasite Immunology.  18:359-369. 1996
1995 Endogenous macrophage CSF production is associated with viral replication in HIV-1-infected human monocyte-derived macrophagesJournal of Immunology.  154:5528-5535. 1995
1995 Modulation of human immunodeficiency virus type 1 infection of human monocytes by igaJournal of Infectious Diseases.  172:855-858. 1995
1995 Role of cytokines in AIDS diarrheaRegulatory Peptide Letter.  6:56-9. 1995
1994 Quantitative analysis of mononuclear cells expressing human immunodeficiency virus type 1 RNA in esophageal mucosaJournal of Experimental Medicine.  180:1541-1546. 1994
1994 Endotoxin administration to humans primes alveolar macrophages for increased production of inflammatory mediatorsJournal of Clinical Immunology.  14:141-148. 1994
1994 Characterization of mucosal antibodies in persons with AIDSJournal of Infectious Diseases.  170:299-307. 1994
1994 Intestinal mucosal immunoglobulins during human immunodeficiency virus type 1 infectionJournal of Infectious Diseases.  170:299-307. 1994
1994 Role of the mucosa in human immunodeficiency virus diseaseMucosal Immunology Update.  2:3-6. 1994
1993 Pulmonary granulomatous hypersensitivity: Cell-mediated responses to embolized schistosome larvae and eggsRegional immunology.  5:165-173. 1993
1993 Esophageal disease in AIDS is associated with pathologic processes rather than mucosal human immunodeficiency virus type 1Journal of Infectious Diseases.  167:547-552. 1993
1993 Immunity to Schistosoma mansoni in mice vaccinated with irradiated cercariae: Cytokine interactions in the pulmonary protective responseAnnals of Tropical Medicine and Parasitology.  87:653-657. 1993
1993 Infectious diarrheas in patients with AIDSGastroenterology Clinics of North America.  22:535-548. 1993
1993 Phenotypic and functional properties of Th lines and clones recognizing larval antigens of Schistosoma mansoniParasite Immunology.  15:373-382. 1993
1992 Surface proteins from helicobacter pylori exhibit chemotactic activity for human leukocytes and are present in gastric mucosaJournal of Experimental Medicine.  175:517-525. 1992
1992 Cytomegalovirus induction of tumor necrosis factor-α by human monocytes and mucosal macrophagesJournal of Clinical Investigation.  90:1642-1648. 1992
1992 Diagnostic workup of AIDS-associated diarrhea [4]Annals of Internal Medicine.  117:346-347. 1992
1992 Immunopathophysiology of gastrointestinal disease in HIV infectionGastroenterology Clinics of North America.  21:331-345. 1992
1992 Monoclonal antibody to IFN-γ modifies pulmonary inflammatory responses and abrogates immunity to Schistosoma mansoni in mice vaccinated with attenuated cercariaeJournal of Immunology.  149:3654-3658. 1992
1992 NIH Staff Conference: Gastrointestinal infections in AIDSAnnals of Internal Medicine.  116:63-77. 1992
1992 T cell-derived cytokines associated with pulmonary immune mechanisms in mice vaccinated with irradiated cercariae of Schistosoma mansoniJournal of Immunology.  148:1512-1518. 1992
1992 The generation of interferon-gamma-producing T lymphocytes in skin-draining lymph nodes, and their recruitment to the lungs, is associated with protective immunity to Schistosoma mansoniImmunology.  75:250-256. 1992
1991 Role of cytokines in infectious and noninfectious enteropathy in patients with AIDSImmunologic Research.  10:447-451. 1991
1991 Adenovirus colitis in the acquired immunodeficiency syndromeGastroenterology.  100:976-979. 1991
1991 Chronic Helicobacter pylori infection of the stomach induces a persistent systemic humoral immune responseFrontiers in Mucosal Immunology.  1:685-8. 1991
1991 Humoral recall responses in HIV infection: Levels, specificity, and affinity of antigen-specific IgGJournal of Immunology.  147:2130-2135. 1991
1991 Inhibitors of reactive oxygen intermediates suppress bacterial cell wall-induced arthritisJournal of Immunology.  147:2559-2564. 1991
1991 Isolation of macrophages/monocytes from human peripheral blood and tissuesCurrent Protocols in Immunology.  7.6.A1-8. 1991
1991 Opportunistic infections in patients with immune dysfunctionUnfallchirurgie.  96:176-80. 1991
1991 Patterns of cytokine production and proliferation by T lymphocytes differ in mice vaccinated or infected with Schistosoma mansoniImmunology.  73:327-333. 1991
1991 Soluble surface proteins from Helicobacter pylori activate monocytes/macrophages by lipopolysaccharide-independent mechanismJournal of Clinical Investigation.  87:894-900. 1991
1990 Candida albicans in patients with the acquired immunodeficiency syndrome: Absence of a novel or hypervirulent strainJournal of Infectious Diseases.  162:513-518. 1990
1990 Expression of interleukin 2 receptors by monocytes from patients with acquired immunodeficiency syndrome and induction of monocyte interleukin 2 receptors by human immunodeficiency virus in vitroJournal of Clinical Investigation.  85:192-199. 1990
1990 Granulocyte-macrophage colony-stimulating factor augments human monocyte fungicidal activity for candida albicansJournal of Infectious Diseases.  161:999-1005. 1990
1990 Granulocyte-macrophage colony-stimulating factor stimulates human monocyte accessory cell functionJournal of Immunology.  144:3829-3834. 1990
1990 Intestinal microsporidiosis as a cause of diarrhea in HIV-infected patients: A report of 20 casesHuman Pathology.  21:475-81. 1990
1990 Intestinal microsporidiosis as a cause of diarrhea in human immunodeficiency virus-infected patients: A report of 20 casesHuman Pathology.  21:475-481. 1990
1990 Subcutaneous recombinant granulocyte-macrophage colony-stimulating factor used as a single agent and in an alternating regimen with azidothymidine in leukopenic patients with severe human immunodeficiency virus infectionBlood.  76:463-472. 1990
1989 A phase I trial of recombinant human interferon-γ in patients with Kaposi's sarcoma and the acquired immunodeficiency syndrome (AIDS)Journal of Clinical Immunology.  9:351-361. 1989
1989 Elevated levels of immunoglobulin A to Giardia lamblia during a waterborne outbreak of gastroenteritisJournal of Clinical Microbiology.  27:1707-1710. 1989
1989 Granulocyte-macrophage colony-stimulating factor augmentation of leukocyte effector cell functionJournal of Cellular Biochemistry.  105:137-41. 1989
1989 Malabsorption of vitamin B12 in the acquired immunodeficiency syndromeArchives of Internal Medicine.  149:2039-41. 1989
1989 Vitamin B 12 malabsorption in patients with acquired immunodeficiency syndromeArchives of Internal Medicine -New Series-.  149:2039-2041. 1989
1988 Acute antibody responses to giardia lamblia are depressed in patients with aidsJournal of Infectious Diseases.  157:798-804. 1988
1988 Infectious diarrhea in human immunodeficiency virus infectionGastroenterology Clinics of North America.  17:587-598. 1988
1988 Intestinal infections in patients with the acquired immunodeficiency syndrome (AIDS). Etiology and response to therapyAnnals of Internal Medicine.  108:328-333. 1988
1988 Perspectives on gastrointestinal infections in AIDSGastroenterology Clinics of North America.  17:451-463. 1988
1987 Monocyte interleukin 2 receptor gene expression and interleukin 2 augmentation of microbicidal activityJournal of Immunology.  139:1342-1347. 1987
1987 Acquired immunodeficiency syndrome: Ga-67 citrate imagingRadiology.  162:383-387. 1987
1987 Gastrointestinal infections in the acquired immunodeficiency syndromeViewpoints in Digestive Diseases.  18:1-4. 1987
1986 Effect of 9-(1,3-dihydroxy-2-propoxymethyl) guanine on serious cytomegalovirus disease in eight immunosuppressed homosexual menAnnals of Internal Medicine.  104:41-44. 1986
1985 Monocyte chemotaxis in the acquired immune deficiency syndrome (AIDS)Federation proceedings.  44. 1985
1985 Pathophysiology and immunology of giardiasis.Annual Review of Medicine.  36:295-307. 1985
1985 Salmonella typhimurium enteritis and bacteremia in the acquired immunodeficiency syndromeAnnals of Internal Medicine.  102:207-209. 1985
1984 Defective spontaneous but normal antibody-dependent cytotoxicity for an extracellular protozoan parasite, Giardia lamblia, by C3H/HeJ mouse macrophagesCellular Immunology.  85:244-251. 1984
1984 Acquired immune deficiency syndrome and multiple tract degeneration in a homosexual manAnnals of Neurology.  15:502-505. 1984
1984 Monocyte function in the acquired immune deficiency syndrome. Defective chemotaxisJournal of Clinical Investigation.  74:2121-2128. 1984
1984 Oxygen-dependent cytotoxicity for Giardia lamblia by human monocytesFederation proceedings.  43. 1984
1983 Excretory-secretory products of Giardia lambliaJournal of Immunology.  131:2004-2010. 1983
1983 Human host response to Giardia lamblia. II. Antibody-dependent killing in vitroCellular Immunology.  82:308-315. 1983
1983 Infectious agents and inflammatory bowel diseaseGastroenterology.  85:475-476. 1983
1982 A search for an enriched source of polymeric IgA in human thoracic duct lymph, portal vein blood and aortic bloodClinical and Experimental Immunology.  48:85-90. 1982
1982 Antigenic analysis of Giardia lamblia from Afghanistan, Puerto Rico, Ecuador, and OregonInfection and Immunity.  36:714-719. 1982
1982 Chronic Giardiasis: Studies on Drug Sensitivity, Toxin Production, and Host Immune ResponseGastroenterology.  83:797-803. 1982
1982 Human host response to Giardia lamblia. I. Spontaneous killing by mononuclear leukocytes in vitroJournal of Immunology.  128:1372-1376. 1982
1981 In vitro studies on bile acid deconjugation and lipolysis inhibition by Giardia lambliaDigestive Diseases and Sciences.  26:700-704. 1981
1981 IgA in human bile and liverJournal of Immunology.  126:587-595. 1981
1981 IgA in human liver and bileJournal of Immunology.  26:587-95. 1981
1981 IgG antibody to Giardia lamblia detected by enzyme-linked immunosorbent assayGastroenterology.  80:1476-1480. 1981
1980 An immunofluorescence test to detect serum antibodies to Giardia lambliaAnnals of Internal Medicine.  93:802-805. 1980
1980 Chronic proctitis in male homosexuals due to lymphogranuloma venereumGastroenterology.  79:563-565. 1980
1977 Gastric varicesAmerican Journal of Digestive Diseases.  22:947-955. 1977
1973 Yeast Chromatin. Preparation from Isolated Nuclei, Histone Composition and Transcription CapacityEuropean Journal of Biochemistry.  33:123-130. 1973
1968 The Effect of Provision of Medical Facilities on Use by the Migrant Workers of CaliforniaMedical Care.  6:394-400. 1968
1967 Genetic factors in human allergic contact dermatitisInternational Archives of Allergy and Applied Immunology.  32:453-62. 1967

Book

Year Title Altmetric
2013 Principles of Mucosal Immunology 2013
1995 Infections of the Gastrointestinal Tract 1995

Chapter

Year Title Altmetric
2015 Mucosal Macrophages in Defense and Regulation.  543-556. 2015
2015 Complications of AIDS and Other Immunodeficiency States.  779-85. 2015
2015 Complications of AIDS and Other Secondary Immunodeficiency States.  2588-611. 2015
2013 Viral Infections.  377-95. 2013
2012 Intestinal macrophages in defense of the mucosa.  159-70. 2012
2009 Complications of AIDS and other Immunodeficiency States.  2588-2611. 2009
2009 Complications of AIDS and Other Immunodeficiency States.  779-86. 2009
2008 Immunologic disease of the gastrointestinal tract.  1099-1114. 2008
2005 Antigen handling and presentation by mucosal dendritic cells and macrophages.  451-485. 2005
2005 Immunobiology of mucosal HIV-1 infection.  1199-1211. 2005
2005 Involvement of Dendritic Cells in the Pathogenesis of Inflammatory Bowel Disease.  117-33. 2005
2003 Approach to Gastrointestinal Problems in the Immunocompromised Patient.  1017-32. 2003
2003 Gastrointestinal Complications of the Acquired Immunodeficiency Syndrome.  741-8. 2003
2003 Gastrointestinal Complications of the Acquired Immunodeficiency Syndrome.  2567-89. 2003
2002 Gastrointestinal Infections in HIV-1 Disease.  417-43. 2002
2001 Macrophage effector function.  19.1-19.9. 2001
1999 Approach to Gastrointestinal Problems in the Immunocompromised Patient.  1034-49. 1999
1999 Gastrointestinal Complications of the Acquired Immunodeficiency Syndrome.  2400-22. 1999
1999 Gastrointestinal Complications of the Acquired Immunodeficiency Syndrome.  510-5. 1999
1999 Immunobiology of Mucosal HIV-1 Infection.  977-89. 1999
1999 Persistent Mucosal Colonization by Helicobacter pylori and the Induction of Inflammation.  1107-16. 1999
1997 The role of the mononuclear phagocyte in H. pylori-associated inflammation.  127-37. 1997
1996 Macrophage Functions in HIV-1 Infection.  303-36. 1996
1995 Esophageal Infections in HIV-1 Disease.  459-70. 1995
1995 Intestinal Infections in HIV-1 Disease.  483-98. 1995
1994 Mucosal Immunopathophysiology of HIV Infection.  719-28. 1994
1993 Granulocyte-macrophage colony-stimmulating factor augmentation of human monocyte/macrophage effector and accessory cell functions.  79-89. 1993
1991 Infections of the large intestine in the immunosuppressed host.  437-44. 1991
1991 Preparation of human mononuclear cell populations and subpopulations.  7.1.1-7.1.5. 1991
1990 The role of immunity in Giardia infections.  215-33. 1990
1989 Cytokines.  241-83. 1989
1989 Parasitic Infections.  379-94. 1989
1988 Giardia lamblia.  343-84. 1988
1988 Infections of the gastrointestinal tract in the acquired immunodeficiency syndrome.  490-9. 1988
1988 Modulation of fiber formation and possible therapeutic strategy.  223-32. 1988
1988 Viral infections of the gastrointestinal tract in patients with AIDS.  46-7. 1988
1985 Cytomegalovirus infection depresses monocyte production of interleukin 1.  319-26. 1985
1984 Human immune responses to Giardia lamblia.  201-18. 1984
1981 The human liver and the secretory immune system.  16-25. 1981

Principal Investigator On

  • Mechanism of Cytomegalovirus-induced Mucosal Inflammation  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2016 - 2020
  • Stem Cell Organogenesis Unit  awarded by UNIVERSITY OF ALABAMA HEALTH SERVICES FOUNDATION 2016 - 2019
  • Private Grant  awarded by BIODTECH, INC 2017 - 2019
  • Role of Gastric Microbiota in Protecting Children from Precancerous Inflammation in H. Pylori Infection  awarded by National Institute of Child Health and Human Development/NIH/DHHS 2017 - 2019
  • Cytomegalovirus Infection Exacerbates Macrophage-driven Inflammation in Inflammatory Bowel Disease  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS 2018 - 2019
  • Elucidating Protective Mechanisms Against Gastric Cancer  awarded by DeGregorio Family Foundation 2015 - 2017
  • Mechanisms of Apoptotic Cell Clearance in the Human Stomach  awarded by University of Virginia 2010 - 2015
  • Private Grant  awarded by BIODTECH, INC 2014 - 2015
  • Mechanisms of Apoptotic Cell Clearance in the Human Stomach  awarded by University of California, San Diego 2011 - 2014
  • Mechanism for CMV-Induced Exacerbation of Inflammation in IBD  awarded by Crohn's & Colitis Foundation of America 2013
  • Mucosal HIV and Immunobiology Center  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2008 - 2013
  • Mechanism for CMV-Induced Exacerbation of Inflammation in IBD  awarded by Crohn's & Colitis Foundation of America 2010 - 2012
  • Role of Intestinal Macrophages in HIV Persistence  awarded by American Foundation for AIDS Research (amfAR) 2011 - 2012
  • Immunologic Uniqueness of the Female Genital Tract in HIV Pathogenesis - Project 1  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS 2009 - 2012
  • Intestinal Extra-Cellular Matrix in Innate Regulation of Mucosal T-Cells  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2010 - 2012
  • Immunobiology and Prevention of H. pylori Disease  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2005 - 2011
  • CHAVI - Center for HIV/AIDS Vaccine Immunology - Smith Mucosal Team  awarded by Duke University 2006 - 2008
  • Teaching Activities

    Education And Training

  • Doctor of Medicine, University of Rochester 1973
  • Vanderbilt University Medical Center, Internship 1974
  • Vanderbilt University Medical Center, Residency 1976
  • University of Colorado Health Sciences Center, Postdoctoral Fellowship 1979
  • Full Name

  • Phillip Smith