Selected Publications

Academic Article

Year Title Altmetric
2022 Association of Polygenic Risk Score with Blood Pressure and Adverse Cardiovascular Outcomes in Individuals with Type II Diabetes: Insights from the ACCORD TrialHypertension.  79:E100-E102. 2022
2022 Association of Transthyretin Val122Ile Variant With Incident Heart Failure Among Black Individuals 2022
2022 Genetic European Ancestry and Incident Diabetes in Black Individuals: Insights from the SPRINT TrialCirculation: Genomic and Precision Medicine.  15:E003468. 2022
2022 Insulin Resistance and Cardiometabolic Risk Profile among Nondiabetic American Young Adults: Insights from NHANESJournal of Clinical Endocrinology and Metabolism.  107:E25-E37. 2022
2022 Nocturnal blood pressure dipping in treated hypertensives: Insights from the SPRINT trialEuropean Journal of Preventive Cardiology.  29:E25-E28. 2022
2022 Relation of Abdominal Obesity to Risk of Atrial Fibrillation (From the Reasons for Geographic and Racial Differences in Stroke [REGARDS] Study)American Journal of Cardiology.  162:116-121. 2022
2021 A retrospective cohort study of 12,306 pediatric COVID-19 patients in the United StatesScientific Reports.  11. 2021
2021 Genotype-Guided P2Y12 Inhibitor Therapy after Percutaneous Coronary Intervention: A Bayesian AnalysisCirculation: Genomic and Precision Medicine.  14:731-739. 2021
2021 Inhaled high dose nitric oxide is a safe and effective respiratory treatment in spontaneous breathing hospitalized patients with COVID-19 pneumoniaNitric Oxide: Biology and Chemistry.  116:7-13. 2021
2021 Sphingosine-1-phosphate interactions in the spleen and heart reflect extent of cardiac repair in mice and failing human hearts 2021
2021 Right Ventricular Strain Is Common in Intubated COVID-19 Patients and Does Not Reflect Severity of Respiratory IllnessJournal of Intensive Care Medicine.  36:900-909. 2021
2021 Geographic Variation in Cardiovascular Health Among American AdultsMayo Clinic Proceedings.  96:1770-1781. 2021
2021 Relative Predictive Value of Circulating Immune Markers in US Adults Without Cardiovascular Disease: Implications for Risk ReclassificationMayo Clinic Proceedings.  96:1812-1821. 2021
2021 Natriuretic Peptide Deficiency in Obese Individuals: Mechanistic Insights From Healthy Organ Donor CohortJournal of the American College of Cardiology.  77:3138-3140. 2021
2021 Coronary artery bypass graft surgery outcomes in the United States: Impact of the coronavirus disease 2019 (COVID-19) pandemic 2021
2021 Diagnostic and prognostic implications of heart failure with preserved ejection fraction scoring systemsESC Heart Failure.  8:2089-2102. 2021
2021 Pleural Pressure Targeted Positive Airway Pressure Improves Cardiopulmonary Function in Spontaneously Breathing Patients With ObesityChest.  159:2373-2383. 2021
2021 Sodium–glucose co-transporter 2 inhibitors: strength of evidence for a cardio-renal-metabolic therapyEuropean Journal of Heart Failure.  23:1009-1011. 2021
2021 Chronobiology of Natriuretic Peptides and Blood Pressure in Lean and Obese IndividualsJournal of the American College of Cardiology.  77:2291-2303. 2021
2021 Geographic Inequalities in Cardiovascular Mortality in the United States: 1999 to 2018Mayo Clinic Proceedings.  96:1218-1228. 2021
2021 N-terminal pro-b-type natriuretic peptide and longitudinal risk of hypertensionAmerican Journal of Hypertension.  34:476-483. 2021
2021 The Dietary Approaches to Stop Hypertension (DASH) Diet Pattern and Incident Heart FailureJournal of Cardiac Failure.  27:512-521. 2021
2021 Increased awareness, inadequate treatment, and poor control of cardiovascular risk factors in American young adults: 2005-2016.European Journal of Preventive Cardiology.  28:304-312. 2021
2021 Association of Genetic West African Ancestry, Blood Pressure Response to Therapy, and Cardiovascular Risk among Self-reported Black Individuals in the Systolic Blood Pressure Reduction Intervention Trial (SPRINT)JAMA Cardiology.  6:388-398. 2021
2021 Trends and Geographic Variation in Acute Respiratory Failure and ARDS Mortality in the United StatesChest.  159:1460-1472. 2021
2021 Increased awareness, inadequate treatment, and poor control of cardiovascular risk factors in American young adults: 2005-2016European Journal of Preventive Cardiology.  28:304-312. 2021
2021 Unexpectedly Low Natriuretic Peptide Levels in Patients With Heart FailureJACC: Heart Failure.  9:192-200. 2021
2021 Reply to Mezidi et al.American Journal of Respiratory and Critical Care Medicine.  203:392-394. 2021
2021 Coronary artery calcium score for personalization of antihypertensive therapy: A pooled cohort analysisHypertension.  1106-1118. 2021
2021 Effects of vitamin d supplementation on cardiovascular and glycemic biomarkers 2021
2021 Obesity and serial nt-probnp levels in guided medical therapy for heart failure with reduced ejection fraction: Insights from the guide-it trial 2021
2020 Geographic Variation in Racial Disparities in Health and Coronavirus Disease-2019 (COVID-19) Mortality. 2020
2020 High Concentrations of Nitric Oxide Inhalation Therapy in Pregnant Patients With Severe Coronavirus Disease 2019 (COVID-19)Obstetrics and Gynecology.  136:1109-1113. 2020
2020 Mortality Due to Mitral Regurgitation Among Adults in the United States: 1999-2018Mayo Clinic Proceedings.  95:2633-2643. 2020
2020 Abstract 17244: Obesity and Serial NT-proBNP Levels in Heart Failure: Insights From the GUIDE-IT TrialCirculation.  142. 2020
2020 Inflammation and Circulating Natriuretic Peptide LevelsCirculation: Heart Failure.  13:135-144. 2020
2020 Prevalence, Awareness, Treatment, and Poor Control of Hypertension Among Young American Adults: Race-Stratified Analysis of the National Health and Nutrition Examination SurveyMayo Clinic Proceedings.  95:1390-1403. 2020
2020 Clinical, Demographic, and Imaging Correlates of Anemia in Heart Failure With Preserved Ejection Fraction (from the RELAX Trial)American Journal of Cardiology.  125:1870-1878. 2020
2020 Implications of Atrial Fibrillation Among Patients With Atherosclerotic Cardiovascular Disease Undergoing Noncardiac SurgeryAmerican Journal of Cardiology.  125:1836-1844. 2020
2020 Incidence and Implications of Atrial Fibrillation/Flutter in Hypertension: Insights from the SPRINT TrialHypertension.  75:1483-1490. 2020
2020 A lung rescue team improves survival in obesity with acute respiratory distress syndrome 2020
2020 Lack of resolution sensor drives age-related cardiometabolic and cardiorenal defects and impedes inflammation-resolution in heart failureMolecular Metabolism.  31:138-149. 2020
2020 Racial differences in serial nt-probnp levels in heart failure management: Insights from the guide-it trialCirculation.  1018-1020. 2020
2019 Trends in Lipid, Lipoproteins, and Statin Use Among U.S. Adults: Impact of 2013 Cholesterol GuidelinesJournal of the American College of Cardiology.  74:2525-2528. 2019
2019 Race, Natriuretic Peptides, and High-Carbohydrate Challenge: A Clinical TrialCirculation Research.  125:957-968. 2019
2019 Glycosylation of natriuretic peptides in obese heart failure: mechanistic insights.Annals of translational medicine.  7:611. 2019
2019 Reevaluating the Use of the Nationwide Inpatient Sample to Identify Incident Cases of Atrial Fibrillation after Aortic Valve Replacement - ReplyJAMA Internal Medicine.  179:1598. 2019
2019 Ideal Cardiovascular Health Among American Adults After the Economic Recession of 2008-2009: Insights from NHANESAmerican Journal of Medicine.  132:1182-1190.e5. 2019
2019 Evaluation of the Incidence of New-Onset Atrial Fibrillation after Aortic Valve ReplacementJAMA Internal Medicine.  179:1122-1130. 2019
2019 Cardiovascular Health and Disease Among Asian-Americans (from the National Health and Nutrition Examination Survey)American Journal of Cardiology.  124:270-277. 2019
2019 Race-based demographic, anthropometric and clinical correlates of N-terminal-pro B-type natriuretic peptideInternational Journal of Cardiology.  286:145-151. 2019
2019 Cardiovascular Events and Hospital Deaths Among Patients With Severe SepsisAmerican Journal of Cardiology.  123:1406-1413. 2019
2019 Lipoprotein(a) and Risk of Ischemic Stroke in the REGARDS Study 2019
2019 Futile MITRA-FR and a positive COAPT trial: Where does the evidence leave the clinicians?International Journal of Cardiology: Heart and Vasculature.  22:18-19. 2019
2019 In-Hospital Management and Outcomes After ST-Segment-Elevation Myocardial Infarction in Medicaid Beneficiaries Compared With Privately Insured IndividualsCirculation: Cardiovascular Quality and Outcomes.  12:e004971. 2019
2019 Racial differences in the association of NT-proBNP with risk of incident heart failure in REGARDSJCI insight.  4. 2019
2018 Incidence and in-hospital outcomes of single-vessel coronary chronic total occlusion treated with percutaneous coronary interventionInternational Journal of Cardiology.  269:61-66. 2018
2018 Interdisciplinary Models for Research and Clinical Endeavors in Genomic Medicine: A Scientific Statement From the American Heart AssociationCirculation: Genomic and Precision Medicine.  11:e000046. 2018
2018 Trends and Cost of Heart Transplantation and Left Ventricular Assist Devices: Impact of Proposed Federal CutsJACC: Heart Failure.  6:424-432. 2018
2018 Neurological effects of proprotein convertase subtilisin/kexin type 9 inhibitors: Direct comparisonsEuropean Heart Journal - Quality of Care and Clinical Outcomes.  4:132-141. 2018
2018 Costs of Transcatheter Aortic Valve Replacement: Implications of Proposed Medicare CutsJACC: Cardiovascular Interventions.  11:610-612. 2018
2018 Effect of NT-proBNP–Guided Therapy on All-Cause Mortality in Chronic Heart Failure With Reduced Ejection FractionJournal of the American College of Cardiology.  71:951-952. 2018
2018 FFR-guided multivessel stenting reduces urgent revascularization compared with infarct-related artery only stenting in ST-elevation myocardial infarction: A meta-analysis of randomized controlled trialsInternational Journal of Cardiology.  252:63-67. 2018
2018 Galectin-3: an emerging biomarker in stroke and cerebrovascular diseasesEuropean Journal of Neurology.  25:238-246. 2018
2018 Galectin-3 and incident cognitive impairment in REGARDS, a cohort of blacks and whitesAlzheimer's and Dementia: Translational Research and Clinical Interventions.  4:165-172. 2018
2018 Hospitalization rates, prevalence of cardiovascular manifestations, and outcomes associated with sarcoidosis in the United States 2018
2018 Racial differences in plasma levels of n-Terminal pro-b-Type natriuretic peptide and outcomes the reasons for geographic and racial differences in stroke (regards) studyJAMA Cardiology.  3:11-17. 2018
2018 Targeted temperature management after cardiac arrest: Systematic review and meta-analysesAnesthesia and Analgesia.  126:867-875. 2018
2017 Galectin-3 and risk of ischaemic stroke: Reasons for Geographic and Racial Differences in Stroke cohortEuropean Journal of Neurology.  24:1464-1470. 2017
2017 Effect of vitamin D supplementation on arterial stiffness and central blood pressure indexes: Demystifying the evidence 2017
2017 Effects of anacetrapib in patients with atherosclerotic vascular diseaseNew England Journal of Medicine.  377:1217-1227. 2017
2017 Percutaneous coronary intervention vs. coronary artery bypass grafting for left main revascularization: An updated meta-analysisEuropean Heart Journal - Quality of Care and Clinical Outcomes.  3:173-182. 2017
2017 Response by Golwala et al to Letter Regarding Article, "implantable Cardioverter-Defibrillator for Nonischemic Cardiomyopathy: An Updated Meta-Analysis"Circulation.  135:e1200-e1202. 2017
2017 Causal effect of plasminogen activator inhibitor type 1 on coronary heart disease 2017
2017 Conducting and interpreting high-quality systematic reviews and meta-analysesJournal of Nuclear Cardiology.  24:471-481. 2017
2017 Surgical Embolectomy for Acute Pulmonary Embolism: Systematic Review and Comprehensive Meta-AnalysesAnnals of Thoracic Surgery.  103:982-990. 2017
2017 Implantable Cardioverter-Defibrillator for Nonischemic Cardiomyopathy: An Updated Meta-AnalysisCirculation.  135:201-203. 2017
2016 Catheter-directed treatment for acute pulmonary embolism: Systematic review and single-arm meta-analysesInternational Journal of Cardiology.  225:128-139. 2016
2016 Comparison of approaches for stroke prophylaxis in patients with non-valvular atrial fibrillation: Network meta-analyses of randomized controlled trialsPLoS ONE.  11. 2016
2016 Acute metabolic influences on the natriuretic peptide system in humansJournal of the American College of Cardiology.  67:804-812. 2016
2016 Vitamin D supplementation modulates t cell-mediated immunity in humans: Results from a randomized control trialJournal of Clinical Endocrinology and Metabolism.  101:533-538. 2016
2016 Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney functionNature Communications.  7. 2016
2016 Noncoding genome-wide association studies variant for obesity: Inroads into mechanism an overview from the aha’s council on functional genomics and translational biology 2016
2016 Novel microRNA regulators of atrial natriuretic peptide productionMolecular and Cellular Biology.  36:1977-1987. 2016
2015 Comparison of approaches to revascularization in patients with multivessel coronary artery disease presenting with st-segment elevation myocardial infarction: Meta-analyses of randomized control trials 2015
2015 Ezetimibe added to statin therapy after acute coronary syndromesNew England Journal of Medicine.  372:2387-2397. 2015
2015 Glycoprotein IIb/IIIa inhibitors improve mortality after aspiration thrombectomy in patients with ST-segment elevation myocardial infarctionInternational Journal of Cardiology.  187:206-207. 2015
2015 A Meta-analysis of Gene Expression Signatures of Blood Pressure and HypertensionPLoS Genetics.  11. 2015
2015 Genetic studies of body mass index yield new insights for obesity biologyNature.  518:197-206. 2015
2015 New genetic loci link adipose and insulin biology to body fat distributionNature.  518:187-196. 2015
2015 Long noncoding Mhrt RNA: Molecular crowbar unravel insights into heart failure treatmentCirculation: Cardiovascular Genetics.  8:213-215. 2015
2015 Weight loss, saline loading, and the natriuretic peptide system 2015
2015 High-Dose versus Low-Dose Vitamin D Supplementation and Arterial Stiffness among Individuals with Prehypertension and Vitamin D DeficiencyDisease Markers.  2015. 2015
2015 Vitamin D therapy in individuals with prehypertension or hypertension the DAYLIGHT trialCirculation.  131:254-262. 2015
2014 Long noncoding RNA-MicroRNA-mRNA a novel tripartite axis in the regulation of cardiac hypertrophyCirculation: Cardiovascular Genetics.  7:729-731. 2014
2014 Effect of darapladib on major coronary events after an acute coronary syndrome: The SOLID-TIMI 52 randomized clinical trial 2014
2014 MicroRNA passenger strand orchestral symphony of paracrine signalingCirculation: Cardiovascular Genetics.  7:567-568. 2014
2014 Obesity genetics and epigenetics: Dissecting causalityCirculation: Cardiovascular Genetics.  7:395-396. 2014
2014 LMKB/MARF1 localizes to mRNA processing bodies, interacts with Ge-1, and regulates IFI44L gene expressionPLoS ONE.  9. 2014
2014 Effect of phosphodiesterase inhibition on insulin resistance in obese individuals 2014
2014 Metabolomics yield a novel biomarker for predicting diabetes mellitus risk in humansCirculation: Cardiovascular Genetics.  7:95-96. 2014
2014 Top advances in functional genomics and translational biology for 2013Circulation: Cardiovascular Genetics.  7:89-92. 2014
2013 Salt, immune function, and the risk of autoimmune diseasesCirculation: Cardiovascular Genetics.  6:642-643. 2013
2013 Effects of subacute dietary salt intake and acute volume expansion on diastolic function in young normotensive individualsEHJ Cardiovascular Imaging / European Heart Journal - Cardiovascular Imaging.  14:1092-1098. 2013
2013 Glucagon-like peptide-1 receptor-atrial natriuretic peptide axis: A novel mechanism for blood pressure regulationCirculation: Cardiovascular Genetics.  6:523. 2013
2013 Atrial natriuretic peptide is negatively regulated by microRNA-425Journal of Clinical Investigation.  123:3378-3382. 2013
2013 Soluble guanylate cyclase a1-deficient mice: A novel murine model for primary open angle glaucomaAnnals of Neurosciences.  20:65-66. 2013
2013 Soluble Guanylate Cyclase α1-Deficient Mice: A Novel Murine Model for Primary Open Angle GlaucomaPLoS ONE.  8. 2013
2013 MicroRNA miR-425 is a negative regulator of atrial natriuretic peptide.BMC Pharmacology and Toxicology.  14:O10-O10. 2013
2011 Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasmaNature Genetics.  43:1131-1138. 2011
2011 Genetic variants in novel pathways influence blood pressure and cardiovascular disease riskNature.  478:103-109. 2011
2011 Cardiac natriuretic peptides, obesity, and insulin resistance: Evidence from two community-based studiesJournal of Clinical Endocrinology and Metabolism.  96:3242-3249. 2011
2011 Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressureNature Genetics.  43:1005-1012. 2011
2011 Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study.Human Molecular Genetics.  20:2273-2284. 2011
2010 Blood pressure and human genetic variation in the general populationCurrent Opinion in Cardiology.  25:229-237. 2010
2010 Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertensionPLoS Genetics.  6:1-11. 2010

Education And Training

  • Bachelor of Medicine & Surgery (MBBS), Manipal University 2003
  • Full Name

  • Pankaj Arora