Positions

Selected Publications

Academic Article

Year Title Altmetric
2022 Mechanical Circulatory Support Devices Among Patients With Familial Dilated Cardiomyopathy: Insights From the INTERMACS.Circulation.  146:1486-1488. 2022
2022 Arachidonate 5-lipoxygenase is essential for biosynthesis of specialized pro-resolving mediators and cardiac repair in heart failureAmerican Journal of Physiology: Heart and Circulatory Physiology.  323:H721-H737. 2022
2022 Risk of Postdischarge Bleeding From Dual Antiplatelet Therapy After Percutaneous Coronary Intervention Among US Black and White AdultsJournal of the American Heart Association.  11. 2022
2022 High-Dose Inhaled Nitric Oxide for the Treatment of Spontaneously Breathing Pregnant Patients with Severe Coronavirus Disease 2019 (COVID-19) PneumoniaObstetrics and Gynecology.  140:195-203. 2022
2022 Frequency, Penetrance, and Variable Expressivity of Dilated Cardiomyopathy-Associated Putative Pathogenic Gene Variants in UK Biobank ParticipantsCirculation.  146:110-124. 2022
2022 Corin Missense Variants, Blood Pressure, and Hypertension in 11 322 Black Individuals: Insights From REGARDS and the Jackson Heart StudyJournal of the American Heart Association.  11. 2022
2022 Association of Polygenic Risk Score with Blood Pressure and Adverse Cardiovascular Outcomes in Individuals with Type II Diabetes: Insights from the ACCORD TrialHypertension.  79:E100-E102. 2022
2022 Association of Transthyretin Val122Ile Variant With Incident Heart Failure Among Black IndividualsJAMA: Journal of the American Medical Association.  327:1368-1378. 2022
2022 Genetic European Ancestry and Incident Diabetes in Black Individuals: Insights from the SPRINT TrialCirculation: Genomic and Precision Medicine.  15:E003468. 2022
2022 Insulin Resistance and Cardiometabolic Risk Profile among Nondiabetic American Young Adults: Insights from NHANESJournal of Clinical Endocrinology and Metabolism.  107:E25-E37. 2022
2022 Nocturnal blood pressure dipping in treated hypertensives: Insights from the SPRINT trialEuropean Journal of Preventive Cardiology.  29:E25-E28. 2022
2022 Relation of Abdominal Obesity to Risk of Atrial Fibrillation (From the Reasons for Geographic and Racial Differences in Stroke [REGARDS] Study)American Journal of Cardiology.  162:116-121. 2022
2021 A retrospective cohort study of 12,306 pediatric COVID-19 patients in the United StatesScientific Reports.  11. 2021
2021 Genotype-Guided P2Y12 Inhibitor Therapy after Percutaneous Coronary Intervention: A Bayesian AnalysisCirculation: Genomic and Precision Medicine.  14:731-739. 2021
2021 Inhaled high dose nitric oxide is a safe and effective respiratory treatment in spontaneous breathing hospitalized patients with COVID-19 pneumoniaNitric Oxide: Biology and Chemistry.  116:7-13. 2021
2021 Sphingosine-1-phosphate interactions in the spleen and heart reflect extent of cardiac repair in mice and failing human heartsAmerican Journal of Physiology: Heart and Circulatory Physiology.  321:H599-H611. 2021
2021 Right Ventricular Strain Is Common in Intubated COVID-19 Patients and Does Not Reflect Severity of Respiratory IllnessJournal of Intensive Care Medicine.  36:900-909. 2021
2021 Geographic Variation in Cardiovascular Health Among American AdultsMayo Clinic Proceedings.  96:1770-1781. 2021
2021 Relative Predictive Value of Circulating Immune Markers in US Adults Without Cardiovascular Disease: Implications for Risk ReclassificationMayo Clinic Proceedings.  96:1812-1821. 2021
2021 Natriuretic Peptide Deficiency in Obese Individuals: Mechanistic Insights From Healthy Organ Donor CohortJournal of the American College of Cardiology.  77:3138-3140. 2021
2021 Coronary artery bypass graft surgery outcomes in the United States: Impact of the coronavirus disease 2019 (COVID-19) pandemic 2021
2021 Diagnostic and prognostic implications of heart failure with preserved ejection fraction scoring systemsESC Heart Failure.  8:2089-2102. 2021
2021 Pleural Pressure Targeted Positive Airway Pressure Improves Cardiopulmonary Function in Spontaneously Breathing Patients With ObesityChest.  159:2373-2383. 2021
2021 Sodium–glucose co-transporter 2 inhibitors: strength of evidence for a cardio-renal-metabolic therapyEuropean Journal of Heart Failure.  23:1009-1011. 2021
2021 Chronobiology of Natriuretic Peptides and Blood Pressure in Lean and Obese IndividualsJournal of the American College of Cardiology.  77:2291-2303. 2021
2021 Geographic Inequalities in Cardiovascular Mortality in the United States: 1999 to 2018Mayo Clinic Proceedings.  96:1218-1228. 2021
2021 N-terminal pro-b-type natriuretic peptide and longitudinal risk of hypertensionAmerican Journal of Hypertension.  34:476-483. 2021
2021 The Dietary Approaches to Stop Hypertension (DASH) Diet Pattern and Incident Heart FailureJournal of Cardiac Failure.  27:512-521. 2021
2021 Increased awareness, inadequate treatment, and poor control of cardiovascular risk factors in American young adults: 2005-2016.European Journal of Preventive Cardiology.  28:304-312. 2021
2021 Association of Genetic West African Ancestry, Blood Pressure Response to Therapy, and Cardiovascular Risk among Self-reported Black Individuals in the Systolic Blood Pressure Reduction Intervention Trial (SPRINT)JAMA Cardiology.  6:388-398. 2021
2021 Coronary Artery Calcium Score for Personalization of Antihypertensive Therapy: A Pooled Cohort AnalysisHypertension.  77:1106-1118. 2021
2021 Trends and Geographic Variation in Acute Respiratory Failure and ARDS Mortality in the United StatesChest.  159:1460-1472. 2021
2021 Increased awareness, inadequate treatment, and poor control of cardiovascular risk factors in American young adults: 2005-2016European Journal of Preventive Cardiology.  28:304-312. 2021
2021 Unexpectedly Low Natriuretic Peptide Levels in Patients With Heart FailureJACC: Heart Failure.  9:192-200. 2021
2021 Reply to Mezidi et al.American Journal of Respiratory and Critical Care Medicine.  203:392-394. 2021
2021 Effects of vitamin d supplementation on cardiovascular and glycemic biomarkersJournal of the American Heart Association.  10. 2021
2021 Obesity and serial nt-probnp levels in guided medical therapy for heart failure with reduced ejection fraction: Insights from the guide-it trialJournal of the American Heart Association.  10. 2021
2020 Geographic Variation in Racial Disparities in Health and Coronavirus Disease-2019 (COVID-19) Mortality.Mayo Clinic Proceedings: Innovations, Quality and Outcomes.  4:703-716. 2020
2020 High Concentrations of Nitric Oxide Inhalation Therapy in Pregnant Patients With Severe Coronavirus Disease 2019 (COVID-19)Obstetrics and Gynecology.  136:1109-1113. 2020
2020 Mortality Due to Mitral Regurgitation Among Adults in the United States: 1999-2018Mayo Clinic Proceedings.  95:2633-2643. 2020
2020 Abstract 17244: Obesity and Serial NT-proBNP Levels in Heart Failure: Insights From the GUIDE-IT TrialCirculation.  142. 2020
2020 Racial Differences in Serial NT-proBNP Levels in Heart Failure Management: Insights From the GUIDE-IT TrialCirculation.  142:1018-1020. 2020
2020 Inflammation and Circulating Natriuretic Peptide LevelsCirculation: Heart Failure.  13:135-144. 2020
2020 Prevalence, Awareness, Treatment, and Poor Control of Hypertension Among Young American Adults: Race-Stratified Analysis of the National Health and Nutrition Examination SurveyMayo Clinic Proceedings.  95:1390-1403. 2020
2020 Clinical, Demographic, and Imaging Correlates of Anemia in Heart Failure With Preserved Ejection Fraction (from the RELAX Trial)American Journal of Cardiology.  125:1870-1878. 2020
2020 Implications of Atrial Fibrillation Among Patients With Atherosclerotic Cardiovascular Disease Undergoing Noncardiac SurgeryAmerican Journal of Cardiology.  125:1836-1844. 2020
2020 Incidence and Implications of Atrial Fibrillation/Flutter in Hypertension: Insights from the SPRINT TrialHypertension.  75:1483-1490. 2020
2020 A lung rescue team improves survival in obesity with acute respiratory distress syndromeCritical Care (UK).  24. 2020
2020 Lack of resolution sensor drives age-related cardiometabolic and cardiorenal defects and impedes inflammation-resolution in heart failureMolecular Metabolism.  31:138-149. 2020
2019 Trends in Lipid, Lipoproteins, and Statin Use Among U.S. Adults: Impact of 2013 Cholesterol GuidelinesJournal of the American College of Cardiology.  74:2525-2528. 2019
2019 Race, Natriuretic Peptides, and High-Carbohydrate Challenge: A Clinical TrialCirculation Research.  125:957-968. 2019
2019 Glycosylation of natriuretic peptides in obese heart failure: mechanistic insights.Annals of translational medicine.  7:611. 2019
2019 Reevaluating the Use of the Nationwide Inpatient Sample to Identify Incident Cases of Atrial Fibrillation after Aortic Valve Replacement - ReplyJAMA Internal Medicine.  179:1598. 2019
2019 Ideal Cardiovascular Health Among American Adults After the Economic Recession of 2008-2009: Insights from NHANESAmerican Journal of Medicine.  132:1182-1190.e5. 2019
2019 Evaluation of the Incidence of New-Onset Atrial Fibrillation after Aortic Valve ReplacementJAMA Internal Medicine.  179:1122-1130. 2019
2019 Cardiovascular Health and Disease Among Asian-Americans (from the National Health and Nutrition Examination Survey)American Journal of Cardiology.  124:270-277. 2019
2019 Race-based demographic, anthropometric and clinical correlates of N-terminal-pro B-type natriuretic peptideInternational Journal of Cardiology.  286:145-151. 2019
2019 Cardiovascular Events and Hospital Deaths Among Patients With Severe SepsisAmerican Journal of Cardiology.  123:1406-1413. 2019
2019 Lipoprotein(a) and Risk of Ischemic Stroke in the REGARDS StudyArteriosclerosis, Thrombosis and Vascular Biology.  39:810-818. 2019
2019 Futile MITRA-FR and a positive COAPT trial: Where does the evidence leave the clinicians?International Journal of Cardiology: Heart and Vasculature.  22:18-19. 2019
2019 In-Hospital Management and Outcomes After ST-Segment-Elevation Myocardial Infarction in Medicaid Beneficiaries Compared With Privately Insured IndividualsCirculation: Cardiovascular Quality and Outcomes.  12:e004971. 2019
2019 Racial differences in the association of NT-proBNP with risk of incident heart failure in REGARDSJCI insight.  4. 2019
2018 Incidence and in-hospital outcomes of single-vessel coronary chronic total occlusion treated with percutaneous coronary interventionInternational Journal of Cardiology.  269:61-66. 2018
2018 Interdisciplinary Models for Research and Clinical Endeavors in Genomic Medicine: A Scientific Statement From the American Heart AssociationCirculation: Genomic and Precision Medicine.  11:e000046. 2018
2018 Trends and Cost of Heart Transplantation and Left Ventricular Assist Devices: Impact of Proposed Federal CutsJACC: Heart Failure.  6:424-432. 2018
2018 Neurological effects of proprotein convertase subtilisin/kexin type 9 inhibitors: Direct comparisonsEuropean Heart Journal - Quality of Care and Clinical Outcomes.  4:132-141. 2018
2018 Costs of Transcatheter Aortic Valve Replacement: Implications of Proposed Medicare CutsJACC: Cardiovascular Interventions.  11:610-612. 2018
2018 Effect of NT-proBNP–Guided Therapy on All-Cause Mortality in Chronic Heart Failure With Reduced Ejection FractionJournal of the American College of Cardiology.  71:951-952. 2018
2018 FFR-guided multivessel stenting reduces urgent revascularization compared with infarct-related artery only stenting in ST-elevation myocardial infarction: A meta-analysis of randomized controlled trialsInternational Journal of Cardiology.  252:63-67. 2018
2018 Galectin-3: an emerging biomarker in stroke and cerebrovascular diseasesEuropean Journal of Neurology.  25:238-246. 2018
2018 Galectin-3 and incident cognitive impairment in REGARDS, a cohort of blacks and whitesAlzheimer's and Dementia: Translational Research and Clinical Interventions.  4:165-172. 2018
2018 Hospitalization rates, prevalence of cardiovascular manifestations, and outcomes associated with sarcoidosis in the United StatesJournal of the American Heart Association.  7. 2018
2018 Racial differences in plasma levels of n-Terminal pro-b-Type natriuretic peptide and outcomes the reasons for geographic and racial differences in stroke (regards) studyJAMA Cardiology.  3:11-17. 2018
2018 Targeted temperature management after cardiac arrest: Systematic review and meta-analysesAnesthesia and Analgesia.  126:867-875. 2018
2017 Galectin-3 and risk of ischaemic stroke: Reasons for Geographic and Racial Differences in Stroke cohortEuropean Journal of Neurology.  24:1464-1470. 2017
2017 Effect of vitamin D supplementation on arterial stiffness and central blood pressure indexes: Demystifying the evidenceJournal of the American Heart Association.  6. 2017
2017 Effects of anacetrapib in patients with atherosclerotic vascular diseaseNew England Journal of Medicine.  377:1217-1227. 2017
2017 Percutaneous coronary intervention vs. coronary artery bypass grafting for left main revascularization: An updated meta-analysisEuropean Heart Journal - Quality of Care and Clinical Outcomes.  3:173-182. 2017
2017 Response by Golwala et al to Letter Regarding Article, "implantable Cardioverter-Defibrillator for Nonischemic Cardiomyopathy: An Updated Meta-Analysis"Circulation.  135:e1200-e1202. 2017
2017 Causal effect of plasminogen activator inhibitor type 1 on coronary heart diseaseJournal of the American Heart Association.  6. 2017
2017 Conducting and interpreting high-quality systematic reviews and meta-analysesJournal of Nuclear Cardiology.  24:471-481. 2017
2017 Surgical Embolectomy for Acute Pulmonary Embolism: Systematic Review and Comprehensive Meta-AnalysesAnnals of Thoracic Surgery.  103:982-990. 2017
2017 Implantable Cardioverter-Defibrillator for Nonischemic Cardiomyopathy: An Updated Meta-AnalysisCirculation.  135:201-203. 2017
2016 Catheter-directed treatment for acute pulmonary embolism: Systematic review and single-arm meta-analysesInternational Journal of Cardiology.  225:128-139. 2016
2016 Comparison of approaches for stroke prophylaxis in patients with non-valvular atrial fibrillation: Network meta-analyses of randomized controlled trialsPLoS One.  11. 2016
2016 Acute metabolic influences on the natriuretic peptide system in humansJournal of the American College of Cardiology.  67:804-812. 2016
2016 Vitamin D supplementation modulates t cell-mediated immunity in humans: Results from a randomized control trialJournal of Clinical Endocrinology and Metabolism.  101:533-538. 2016
2016 Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney functionNature Communications.  7. 2016
2016 Noncoding genome-wide association studies variant for obesity: Inroads into mechanism an overview from the aha’s council on functional genomics and translational biologyJournal of the American Heart Association.  5. 2016
2016 Novel microRNA regulators of atrial natriuretic peptide productionMolecular and Cellular Biology.  36:1977-1987. 2016
2015 Comparison of approaches to revascularization in patients with multivessel coronary artery disease presenting with st-segment elevation myocardial infarction: Meta-analyses of randomized control trialsJournal of the American Heart Association.  4. 2015
2015 Ezetimibe added to statin therapy after acute coronary syndromesNew England Journal of Medicine.  372:2387-2397. 2015
2015 Glycoprotein IIb/IIIa inhibitors improve mortality after aspiration thrombectomy in patients with ST-segment elevation myocardial infarctionInternational Journal of Cardiology.  187:206-207. 2015
2015 A Meta-analysis of Gene Expression Signatures of Blood Pressure and HypertensionPLoS Genetics.  11. 2015
2015 Genetic studies of body mass index yield new insights for obesity biologyNature.  518:197-206. 2015
2015 New genetic loci link adipose and insulin biology to body fat distributionNature.  518:187-196. 2015
2015 Long noncoding Mhrt RNA: Molecular crowbar unravel insights into heart failure treatmentCirculation: Cardiovascular Genetics.  8:213-215. 2015
2015 Weight loss, saline loading, and the natriuretic peptide systemJournal of the American Heart Association.  4:e001265. 2015
2015 High-Dose versus Low-Dose Vitamin D Supplementation and Arterial Stiffness among Individuals with Prehypertension and Vitamin D DeficiencyDisease Markers.  2015. 2015
2015 Vitamin D therapy in individuals with prehypertension or hypertension the DAYLIGHT trialCirculation.  131:254-262. 2015
2014 Long noncoding RNA-MicroRNA-mRNA a novel tripartite axis in the regulation of cardiac hypertrophyCirculation: Cardiovascular Genetics.  7:729-731. 2014
2014 Effect of darapladib on major coronary events after an acute coronary syndrome: The SOLID-TIMI 52 randomized clinical trialJAMA: Journal of the American Medical Association.  312:1006-1015. 2014
2014 MicroRNA passenger strand orchestral symphony of paracrine signalingCirculation: Cardiovascular Genetics.  7:567-568. 2014
2014 Obesity genetics and epigenetics: Dissecting causalityCirculation: Cardiovascular Genetics.  7:395-396. 2014
2014 LMKB/MARF1 localizes to mRNA processing bodies, interacts with Ge-1, and regulates IFI44L gene expressionPLoS One.  9. 2014
2014 Effect of phosphodiesterase inhibition on insulin resistance in obese individualsJournal of the American Heart Association.  3. 2014
2014 Metabolomics yield a novel biomarker for predicting diabetes mellitus risk in humansCirculation: Cardiovascular Genetics.  7:95-96. 2014
2014 Top advances in functional genomics and translational biology for 2013Circulation: Cardiovascular Genetics.  7:89-92. 2014
2013 Salt, immune function, and the risk of autoimmune diseasesCirculation: Cardiovascular Genetics.  6:642-643. 2013
2013 Effects of subacute dietary salt intake and acute volume expansion on diastolic function in young normotensive individualsEHJ Cardiovascular Imaging / European Heart Journal - Cardiovascular Imaging.  14:1092-1098. 2013
2013 Glucagon-like peptide-1 receptor-atrial natriuretic peptide axis: A novel mechanism for blood pressure regulationCirculation: Cardiovascular Genetics.  6:523. 2013
2013 MicroRNA miR-425 is a negative regulator of atrial natriuretic peptideBMC Pharmacology and Toxicology.  14:o10. 2013
2013 Atrial natriuretic peptide is negatively regulated by microRNA-425Journal of Clinical Investigation.  123:3378-3382. 2013
2013 Soluble guanylate cyclase a1-deficient mice: A novel murine model for primary open angle glaucomaAnnals of Neurosciences.  20:65-66. 2013
2013 Soluble Guanylate Cyclase α1-Deficient Mice: A Novel Murine Model for Primary Open Angle GlaucomaPLoS One.  8. 2013
2011 Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasmaNature Genetics.  43:1131-1138. 2011
2011 Genetic variants in novel pathways influence blood pressure and cardiovascular disease riskNature.  478:103-109. 2011
2011 Cardiac natriuretic peptides, obesity, and insulin resistance: Evidence from two community-based studiesJournal of Clinical Endocrinology and Metabolism.  96:3242-3249. 2011
2011 Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressureNature Genetics.  43:1005-1012. 2011
2011 Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study.Human Molecular Genetics.  20:2273-2284. 2011
2010 Blood pressure and human genetic variation in the general populationCurrent Opinion in Cardiology.  25:229-237. 2010
2010 Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertensionPLoS Genetics.  6:1-11. 2010

Education And Training

  • Bachelor of Medicine & Surgery (MBBS), Manipal University 2003
  • Full Name

  • Pankaj Arora