Positions

Selected Publications

Academic Article

Year Title Altmetric
2019 Race-based demographic, anthropometric and clinical correlates of N-terminal-pro B-type natriuretic peptideInternational Journal of Cardiology.  286:145-151. 2019
2019 Association of Urine Albumin Excretion With Incident Heart Failure Hospitalization in Community-Dwelling AdultsJACC: Heart Failure.  7:394-401. 2019
2019 Brief Report: Kidney Dysfunction Does Not Contribute Significantly to Antiretroviral Therapy Modification in Treatment-Naive PLWH Receiving Initial ARTJournal of Acquired Immune Deficiency Syndromes.  81. 2019
2019 Dietary Patterns and Incident Heart Failure in U.S. Adults Without Known Coronary DiseaseJournal of the American College of Cardiology.  73:2036-2045. 2019
2019 Relationship of Estimated GFR and Albuminuria to Concurrent Laboratory Abnormalities: An Individual Participant Data Meta-analysis in a Global ConsortiumAmerican Journal of Kidney Diseases.  73:206-217. 2019
2019 A PheWAS study of a large observational epidemiological cohort of African Americans from the REGARDS studyBMC Medical Genomics.  12. 2019
2019 Adiposity and risk of decline in glomerular filtration rate: Meta-analysis of individual participant data in a global consortiumBMJ.  364. 2019
2018 Adherence to Mediterranean-style diet and risk of sepsis in the REasons for Geographic and Racial Differences in Stroke (REGARDS) cohortBritish Journal of Nutrition.  120:1415-1421. 2018
2018 The Role of Vitamin D in CKD Stages 3 to 4: Report of a Scientific Workshop Sponsored by the National Kidney FoundationAmerican Journal of Kidney Diseases.  72:834-845. 2018
2018 Serum albumin concentration and risk of end-stage renal disease: The REGARDS studyNephrology Dialysis Transplantation.  33:1770-1777. 2018
2018 Plasma 25-hydroxyvitamin D and the Longitudinal Risk of Sepsis in the REGARDS Cohort.Clinical Infectious Diseases2018
2018 Serum Calcitriol Concentrations and Kidney Function Decline, Heart Failure, and Mortality in Elderly Community-Living Adults: The Health, Aging, and Body Composition StudyAmerican Journal of Kidney Diseases.  72:419-428. 2018
2018 Urinary Biomarkers of Kidney Tubular Damage and Risk of Cardiovascular Disease and Mortality in EldersAmerican Journal of Kidney Diseases.  72:205-213. 2018
2018 FGF23 (fibroblast growth factor-23) and incident hypertension in young and middle-aged adults: The CARDIA studyHypertension.  72:70-76. 2018
2018 Association of serum albumin levels with kidney function decline and incident chronic kidney disease in eldersNephrology Dialysis Transplantation.  33:986-992. 2018
2018 Dietary Oxidative Balance Scores and Biomarkers of Inflammation among Individuals with and without Chronic Kidney DiseaseNephron Extra.  8:11-23. 2018
2018 Fibroblast Growth Factor 23: A Biomarker of Kidney Function DeclineAmerican Journal of Nephrology.  47:242-250. 2018
2018 Association of fibroblast growth factor 23 with risk of incident coronary heart disease in community-living adultsJAMA Cardiology.  3:318-325. 2018
2018 APOL1 nephropathy risk variants do not associate with subclinical atherosclerosis or left ventricular mass in middle-aged black adultsKidney International.  93:727-732. 2018
2018 Effect of calcitriol on serum hepcidin in individuals with chronic kidney disease: A randomized controlled trialBMC Nephrology.  19. 2018
2018 Racial differences in plasma levels of n-Terminal pro-b-Type natriuretic peptide and outcomes the reasons for geographic and racial differences in stroke (regards) studyJAMA Cardiology.  3:11-17. 2018
2017 Association between APOL1 genotypes and risk of cardiovascular disease in MESA (Multi-Ethnic Study of Atherosclerosis)Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease.  6. 2017
2017 KDOQI US Commentary on the 2017 KDIGO Clinical Practice Guideline Update for the Diagnosis, Evaluation, Prevention, and Treatment of Chronic Kidney Disease–Mineral and Bone Disorder (CKD-MBD)American Journal of Kidney Diseases.  70:737-751. 2017
2017 APOL1 genetic variants are not associated with longitudinal blood pressure in young black adultsKidney International.  92:964-971. 2017
2017 Urinary Markers of Fibrosis and Risk of Cardiovascular Events and Death in Kidney Transplant Recipients: The FAVORIT TrialAmerican Journal of Transplantation.  17:2640-2649. 2017
2017 Global cardiovascular and renal outcomes of reduced GFRJournal of the American Society of Nephrology.  28:2167-2179. 2017
2017 Sickle cell trait and the risk of ESRD in blacksJournal of the American Society of Nephrology.  28:2180-2187. 2017
2017 Association between soluble klotho and change in kidney function: The health aging and body composition studyJournal of the American Society of Nephrology.  28:1859-1866. 2017
2017 Oxidative Balance Score and the Risk of End-Stage Renal Disease and Cardiovascular DiseaseAmerican Journal of Nephrology.  45:338-345. 2017
2017 BP control and long-term risk of ESRD and mortalityJournal of the American Society of Nephrology.  28:671-677. 2017
2017 Albuminuria, kidney function, and sudden cardiac death: Findings from The Reasons for Geographic and Racial Differences in Stroke (REGARDS) studyHeart Rhythm.  14:65-71. 2017
2017 Association of urinary uromodulin with kidney function decline and mortality: The health ABC studyClinical Nephrology.  87:278-286. 2017
2016 Response by Gutiérrez et al to letter regarding article, "Hemoglobin concentration and risk of incident stroke in community-living adults"Stroke.  47:e260. 2016
2016 Vitamin D, Fibroblast growth factor 23 and incident cognitive impairment: Findings from the REGARDS studyPLoS ONE.  11. 2016
2016 Associations of 25-hydroxyvitamin D with markers of inflammation, insulin resistance and obesity in black and white community-dwelling adultsJournal of Clinical and Translational Endocrinology.  5:21-25. 2016
2016 Associations of blood pressure, sunlight, and Vitamin D in community-dwelling adultsJournal of Hypertension.  34:1704-1710. 2016
2016 Hemoglobin Concentration and Risk of Incident Stroke in Community-Living AdultsStroke.  47:2017-2024. 2016
2016 Connecting the dots on fibroblast growth factor 23 and left ventricular hypertrophyNephrology Dialysis Transplantation.  31:1031-1033. 2016
2016 Disorders of Iron Metabolism and Anemia in Chronic Kidney DiseaseSeminars in Nephrology.  36:252-261. 2016
2016 Admixture mapping of serum vitamin D and parathyroid hormone concentrations in the African American-Diabetes Heart StudyBONE.  87:71-77. 2016
2016 Fibroblast growth factor 23 and heart failure: The plot thickensNephrology Dialysis Transplantation.  31:688-690. 2016
2016 Genetic african ancestry and markers of mineral metabolism in CKDClinical Journal of the American Society of Nephrology.  11:653-662. 2016
2016 APOL1 nephropathy risk variants are associated with altered high-density lipoprotein profiles in African AmericansNephrology Dialysis Transplantation.  31:602-608. 2016
2016 The role of cystatin-C in the confirmation of reduced glomerular filtration rate among the oldest oldArchives of Medical Science.  12:55-67. 2016
2016 Association of reduced eGFR and albuminuria with serious fall injuries among older adultsClinical Journal of the American Society of Nephrology.  11:1236-1243. 2016
2016 Vitamin D deficiency and incident stroke risk in community-living black and white adultsInternational Journal of Stroke.  11:93-102. 2016
2016 Waist Circumference, Body Mass Index, and ESRD in the REGARDS (Reasons for Geographic and Racial Differences in Stroke) StudyAmerican Journal of Kidney Diseases.  67:62-69. 2016
2015 Oxidative Balance Score and Chronic Kidney DiseaseAmerican Journal of Nephrology.  42:320-327. 2015
2015 Impact of phosphorus-based food additives on bone and mineral metabolismJournal of Clinical Endocrinology and Metabolism.  100:4264-4271. 2015
2015 Validation of an albuminuria self-assessment tool in the Multi-Ethnic Study of Atherosclerosis (MESA)Ethnicity and Disease.  25:427-434. 2015
2015 Estimated glomerular filtration rate and albuminuria for prediction of cardiovascular outcomes: A collaborative meta-analysis of individual participant dataLancet Diabetes and Endocrinology.  3:514-525. 2015
2015 Diet patterns and risk of sepsis in community-dwelling adults: A cohort studyBMC Infectious Diseases.  15. 2015
2015 Obesity, metabolic health, and the risk of end-stage renal diseaseKidney International.  87:1216-1222. 2015
2015 APOL1 G1 genotype modifies the association between HDLC and kidney function in African AmericansBMC Genomics.  16. 2015
2015 Cystatin C and long term risk of community-acquired sepsis: A population-based cohort studyBMC Nephrology.  1-10. 2015
2015 Associations of fibroblast growth factor-23 with markers of inflammation, insulin resistance and obesity in adultsPLoS ONE.  10. 2015
2015 Fibroblast growth factor 23 and risk of incident stroke in community-living adultsStroke.  46:322-328. 2015
2015 Bone mineral content as a driver of energy expenditure in prepubertal and early pubertal boysJournal of Pediatrics.  166:1397-1403. 2015
2015 Circulating levels of fibroblast growth factor-21 increase with age independently of body composition indices among healthy individualsJournal of Clinical and Translational Endocrinology.  2:77-82. 2015
2015 Contextual poverty, nutrition, and chronic kidney diseaseAdvances in Renal Replacement Therapy.  22:31-38. 2015
2015 Contrasting cholesterol management guidelines for adults with CKDJournal of the American Society of Nephrology.  26:1173-1180. 2015
2015 Fibroblast growth factor-21, body composition, and insulin resistance in pre-pubertal and early pubertal males and femalesClinical Endocrinology.  82:550-556. 2015
2015 Prehospitalization risk factors for acute kidney injury during hospitalization for serious infections in the REGARDS cohortNephron Extra.  5:87-99. 2015
2015 Response to Letter Regarding Article, "fibroblast Growth Factor 23 and Risk of Incident Stroke in Community-Living Adults"Stroke.  46:e124. 2015
2015 Validation study of medicare claims to identify older US adults with CKD using the reasons for geographic and racial differences in stroke (REGARDS) studyAmerican Journal of Kidney Diseases.  65:249-258. 2015
2014 Reply to MF McCartyAmerican Journal of Clinical Nutrition.  99:966-967. 2014
2014 High dietary phosphorus intake is associated with all-cause mortality: Results from NHANES III1-3American Journal of Clinical Nutrition.  99:320-327. 2014
2014 Contribution of Food Additives to Sodium and Phosphorus Content of Diets Rich in Processed FoodsJournal of Renal Nutrition.  24. 2014
2014 Dietary patterns and risk of death and progression to ESRD in individuals with CKD: A cohort studyAmerican Journal of Kidney Diseases.  64:204-213. 2014
2014 Incident ESRD and treatment-resistant hypertension: The reasons for geographic and racial differences in stroke (REGARDS) studyAmerican Journal of Kidney Diseases.  63:781-788. 2014
2014 Low income, community poverty and risk of end stage renal diseaseBMC Nephrology.  15. 2014
2014 N-terminal pro-B-type natriuretic peptide and stroke risk: The reasons for geographic and racial differences in stroke cohortStroke.  45:1646-1650. 2014
2014 Nondisease-specific problems and all-cause mortality among older adults with CKD: The REGARDS studyClinical Journal of the American Society of Nephrology.  9:1737-1745. 2014
2014 The association between race and income on riskof mortality in patients with moderate chronic kidney diseaseBMC Nephrology.  15. 2014
2013 Metabolic subtypes and risk of mortality in normal weight, overweight, and obese individuals with CKDClinical Journal of the American Society of Nephrology.  8:2064-2071. 2013
2013 Dietary patterns are associated with incident stroke and contribute to excess risk of stroke in black americansStroke.  44:3305-3311. 2013
2013 Prevalence of apparent treatment-resistant hypertension among individuals with CKDClinical Journal of the American Society of Nephrology.  8:1583-1590. 2013
2013 Chronic Kidney Disease in African Americans: Past, Present, and Future: IntroductionSeminars in Nephrology.  33:407-408. 2013
2013 Fibroblast growth factor 23, vitamin d, and health disparities among african americans with chronic kidney diseaseSeminars in Nephrology.  33:448-456. 2013
2013 Association between urinary albumin excretion and coronary heart disease in black vs white adultsJournal of the American Medical Association.  310:706-713. 2013
2013 Cardiovascular risk factors in CKD associate with both ESRD and mortalityJournal of the American Society of Nephrology.  24:1159-1165. 2013
2013 Effects of dietary phosphate restriction and phosphate binders on FGF23 levels in CKDClinical Journal of the American Society of Nephrology.  8:1009-1018. 2013
2013 α-Klotho and kidney function decline: An important step forward in understanding the link between mineral metabolism and kidney disease progressionAmerican Journal of Kidney Diseases.  61:855-857. 2013
2013 Fibroblast Growth Factor 23, Klotho, and Disordered Mineral Metabolism in Chronic Kidney Disease: Unraveling the Intricate Tapestry of Events and Implications for TherapyJournal of Renal Nutrition.  23:250-254. 2013
2013 Geographic variation in CKD prevalence and ESRD incidence in the united states: Results from the reasons for geographic and racial differences in stroke (REGARDS) studyAmerican Journal of Kidney Diseases.  61:395-403. 2013
2013 Healthy behaviors, risk factor control and awareness of chronic kidney diseaseAmerican Journal of Nephrology.  37:135-143. 2013
2013 Sodium- and Phosphorus-Based Food Additives: Persistent but Surmountable Hurdles in the Management of Nutrition in Chronic Kidney DiseaseAdvances in Renal Replacement Therapy.  20:150-156. 2013
2013 Associations of Dietary Phosphorus Intake, Urinary Phosphate Excretion, and Fibroblast Growth Factor 23 With Vascular Stiffness in Chronic Kidney DiseaseJournal of Renal Nutrition.  23:12-20. 2013
2013 Fibroblast growth factor 23, high-sensitivity cardiac troponin, and left ventricular hypertrophy in CKDAmerican Journal of Kidney Diseases.  61:67-73. 2013
2013 Risk for recurrent coronary heart disease and all-cause mortality among individuals with chronic kidney disease compared with diabetes mellitus, metabolic syndrome, and cigarette smokersAmerican Heart Journal.  166. 2013
2013 The connection between dietary phosphorus, cardiovascular disease, and mortality: Where we stand and what we need to knowAdvances in Nutrition.  4:723-729. 2013
2012 Racial differences in albuminuria, kidney function, and risk of strokeNeurology.  79:1686-1692. 2012
2012 Statement of concern about a commercial assay used to measure soluble hemojuvelin in humansAmerican Journal of Nephrology.  36:332-333. 2012
2012 Associations of Socioeconomic Status and Processed Food Intake With Serum Phosphorus Concentration in Community-Living Adults: The Multi-Ethnic Study of Atherosclerosis (MESA)Journal of Renal Nutrition.  22:480-489. 2012
2012 High-dose cholecalciferol reduces parathyroid hormone in patients with early chronic kidney disease: A pilot, randomized, double-blind, placebo-controlled trialAmerican Journal of Clinical Nutrition.  96:672-679. 2012
2012 Prevalence and prognosis of unrecognized myocardial infarctions in chronic kidney diseaseNephrology Dialysis Transplantation.  27:3482-3488. 2012
2012 Blood pressure indexes and end-stage renal disease risk in adults with chronic kidney diseaseAmerican Journal of Hypertension.  25:789-796. 2012
2012 Tubular markers are associated with decline in kidney function in proteinuric type 2 diabetic patientsDiabetes Research and Clinical Practice.  97:71-76. 2012
2012 Earlier onset and greater severity of disordered mineral metabolism in diabetic patients with chronic kidney diseaseDiabetes Care.  35:994-1001. 2012
2012 (1-34) parathyroid hormone infusion acutely lowers fibroblast growth factor 23 concentrations in adult volunteersClinical Journal of the American Society of Nephrology.  7:139-145. 2012
2011 Age-specific associations of reduced estimated glomerular filtration rate with concurrent chronic kidney disease complicationsClinical Journal of the American Society of Nephrology.  6:2822-2828. 2011
2011 Fibroblast growth factor 23, cardiovascular disease risk factors, and phosphorus intake in the health professionals follow-up studyClinical Journal of the American Society of Nephrology.  6:2871-2878. 2011
2011 Recent insights into racial differences in bone and mineral metabolismCurrent Opinion in Endocrinology and Diabetes.  18:347-351. 2011
2011 FGF23 induces left ventricular hypertrophyJournal of Clinical Investigation.  121:4393-4408. 2011
2011 Hepcidin and disordered mineral metabolism in chronic kidney diseaseClinical Nephrology.  76:90-98. 2011
2011 Vitamin D Deficiency, Inflammation, and Albuminuria in Chronic Kidney Disease: Complex InteractionsJournal of Renal Nutrition.  21:295-302. 2011
2011 Fibroblast growth factor 23 and risks of mortality and end-stage renal disease in patients with chronic kidney diseaseJournal of the American Medical Association.  305:2432-2439. 2011
2011 Racial differences in the relationship between vitamin D, bone mineral density, and parathyroid hormone in the National Health and Nutrition Examination SurveyOsteoporosis International.  22:1745-1753. 2011
2011 Increased serum phosphate and adverse clinical outcomes: Unraveling mechanisms of diseaseCurrent Opinion in Nephrology and Hypertension.  20:224-228. 2011
2011 Diuretics, calciuria and secondary hyperparathyroidism in the Chronic Renal Insufficiency CohortNephrology Dialysis Transplantation.  26:1258-1265. 2011
2011 Impact of Poverty on Serum Phosphate Concentrations in the Third National Health and Nutrition Examination SurveyJournal of Renal Nutrition.  21:140-148. 2011
2011 Pilot study of dietary phosphorus restriction and phosphorus binders to target fibroblast growth factor 23 in patients with chronic kidney diseaseNephrology Dialysis Transplantation.  26:584-591. 2011
2011 Fibroblast growth factor 23 is elevated before parathyroid hormone and phosphate in chronic kidney diseaseKidney International.  79:1370-1378. 2011
2010 Racial differences in postprandial mineral ion handling in health and in chronic kidney diseaseNephrology Dialysis Transplantation.  25:3970-3977. 2010
2010 Low socioeconomic status associates with higher serum phosphate irrespective of raceJournal of the American Society of Nephrology.  21:1953-1960. 2010
2010 Fibroblast growth factor 23 and disordered vitamin D metabolism in chronic kidney disease: Updating the "trade-off" hypothesisClinical Journal of the American Society of Nephrology.  5:1710-1716. 2010
2010 Dietary phosphorus restriction in advanced chronic kidney disease: Merits, challenges, and emerging strategiesSeminars in Dialysis.  23:401-406. 2010
2010 Vitamin D deficiency and anemia in early chronic kidney diseaseKidney International.  77:715-720. 2010
2010 Response to Targeting hyperphosphatemia: Truth or dareKidney International.  77:257. 2010
2010 The authors replyKidney International.  77:743-744. 2010
2010 The authors replyKidney International.  77:930. 2010
2009 A blueprint for randomized trials targeting phosphorus metabolism in chronic kidney diseaseKidney International.  76:705-716. 2009
2009 Fibroblast growth factor 23 and left ventricular hypertrophy in chronic kidney diseaseCirculation.  119:2545-2552. 2009
2009 Plasma gelsolin and circulating actin correlate with hemodialysis mortalityJournal of the American Society of Nephrology.  20:1140-1148. 2009
2009 Phosphorus binders and survival on hemodialysisJournal of the American Society of Nephrology.  20:388-396. 2009
2008 Fibroblast growth factor 23 and mortality among patients undergoing hemodialysisNew England Journal of Medicine.  359:584-592. 2008
2008 N-terminal pro-B-type natriuretic peptide (NT-proBNP) concentrations in hemodialysis patients: Prognostic value of baseline and follow-up measurementsClinical Chemistry.  54:1339-1348. 2008
2008 Impact of activated vitamin D and race on survival among hemodialysis patientsJournal of the American Society of Nephrology.  19:1379-1388. 2008
2008 Postprandial mineral metabolism and secondary hyperparathyroidism in early CKDJournal of the American Society of Nephrology.  19:615-623. 2008
2008 Prevalence and severity of disordered mineral metabolism in Blacks with chronic kidney diseaseKidney International.  73:956-962. 2008
2007 Vitamin D levels and early mortality among incident hemodialysis patientsKidney International.  72:1004-1013. 2007
2007 Emphysematous pyelonephritisKidney International.  71:462-465. 2007
2007 Refractory hyponatremiaKidney International.  71:79-82. 2007
2006 Post-transplant hypophosphatemia: Tertiary 'Hyper-Phosphatoninism'?Kidney International.  70:1486-1494. 2006
2005 Fibroblast growth factor-23 mitigates hyperphosphatemia but accentuates calcitriol deficiency in chronic kidney diseaseJournal of the American Society of Nephrology.  16:2205-2215. 2005
1999 CACP, encoding a secreted proteoglycan, is mutated in camptodactyly- arthropathy-coxa vara-pericarditis syndromeNature Genetics.  23:319-322. 1999

Chapter

Year Title Altmetric
2017 Impact of socioeconomic factors on phosphorus balance.  213-220. 2017
2013 Disorders of Phosphorus Homeostasis: Emerging Targets for Slowing Progression of Chronic Kidney Disease.  249-255. 2013

Principal Investigator On

Investigator On

  • Race, Natriuretic Peptides and Physiological Perturbations  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2019 - 2024
  • PRedOctoral Phd and MD Research Training In TEams (PROmoTE)  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2019 - 2024
  • UAB-UCSD O'Brien Center for Acute Kidney Injury Research  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2018 - 2023
  • UAB-UCSD O'Brien Center for Acute Kidney Injury Research - Admin Core  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2018 - 2023
  • 3/3 Morehouse School of Medicine/Tuskegee University/University of Alabama Cancer Center Partnership  awarded by National Cancer Institute/NIH/DHHS 2016 - 2021
  • Racial Differences in the Natriuretic Peptide Response to Exercise and Beta-blockers  awarded by American Heart Association 2018 - 2021
  • FGF23: A Novel Biomarker in ALS and More  awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS 2019 - 2021
  • University of Alabama at Birmingham Strategically Focused Hypertension Research Center - Mechanisms of Nocturnal Hypertension and Non-Dipping Blood Pressure - Project 2  awarded by American Heart Association 2015 - 2020
  • Private Grant  awarded by AMGEN, INC. 2018 - 2019
  • University of Alabama at Birmingham Strategically Focused Hypertension Research Center  awarded by American Heart Association 2015 - 2019
  • Targeting the Interactions Between Disordered Iron Homeostasis and Mineral Metabolism in Chronic Kidney Disease to Improve Cardiovascular Outcomes  awarded by American Heart Association 2017 - 2018
  • Novel Regulators of Fibroblast Growth Factor 23 in Chronic Kidney Disease: Iron Deficiency and Hypoxia  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2017 - 2018
  • UAB/UCSD O'Brien Core Center for Acute Kidney Injury Research  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2013 - 2018
  • UAB/UCSD O'Brien Core Center for Acute Kidney Injury Research - Administrative Core  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2013 - 2018
  • Private Grant  awarded by AMGEN, INC. 2008 - 2016
  • Education And Training

  • Doctor of Medicine in Nephrology Residency Program, University of Toledo 2002
  • Massachusetts General Hospital, Internship 2003
  • Massachusetts General Hospital, Residency 2005
  • Brigham & Women's Hospital, Postdoctoral Fellowship 2008
  • Full Name

  • Orlando Gutierrez