Positions

Selected Publications

Academic Article

Year Title Altmetric
2017 Pilus biogenesis of Gram-positive bacteria: Roles of sortases and implications for assemblyProtein Science.  26:1458-1473. 2017
2013 Secreted proteases control autolysin-mediated biofilm growth of Staphylococcus aureus.Journal of Biological Chemistry.  288:29440-29452. 2013
2013 Structure of Streptococcus agalactiae tip pilin GBS104: a model for GBS pili assembly and host interactions.Acta Crystallographica Section D: Biological Crystallography.  69:1073-1089. 2013
2013 Purification, crystallization and preliminary X-ray diffraction analysis of the Staphylococcus epidermidis extracellular serine protease Esp.Acta Crystallographica Section F: Structural Biology and Crystallization Communications.  69:49-52. 2013
2011 The crystal structure analysis of group B Streptococcus sortase C1: a model for the "lid" movement upon substrate binding.Journal of Molecular Biology.  414:563-577. 2011
2011 Two autonomous structural modules in the fimbrial shaft adhesin FimA mediate Actinomyces interactions with streptococci and host cells during oral biofilm development.Microbiological sciences.  81:1205-1220. 2011
2011 Structural and biochemical characterization of Staphylococcus aureus clumping factor B/ligand interactions.Journal of Biological Chemistry.  286:25963-25972. 2011
2011 Structural biology of Gram-positive bacterial adhesins.Protein Science.  20:759-772. 2011
2011 A model for group B Streptococcus pilus type 1: the structure of a 35-kDa C-terminal fragment of the major pilin GBS80.Journal of Molecular Biology.  407:731-743. 2011
2011 Crystallography of gram-positive bacterial adhesins.Advances in Experimental Medicine and Biology.  715:175-195. 2011
2011 Structural differences between the Streptococcus agalactiae housekeeping and pilus-specific sortases: SrtA and SrtC1.PLoS ONE.  6:e22995. 2011
2010 Purification, crystallization and halide phasing of a Streptococcus agalactiae backbone pilin GBS80 fragment.Acta Crystallographica Section F: Structural Biology and Crystallization Communications.  66:1666-1669. 2010
2010 Preliminary crystallographic study of the Streptococcus agalactiae sortases, sortase A and sortase C1.Acta Crystallographica Section F: Structural Biology and Crystallization Communications.  66:1096-1100. 2010
2009 The crystal structure of cobra venom factor, a cofactor for C3- and C5-convertase CVFBb.Structure.  17:611-619. 2009
2009 The structure of C2b, a fragment of complement component C2 produced during C3 convertase formation.Acta Crystallographica Section D: Biological Crystallography.  65:266-274. 2009
2008 Evidence for the "dock, lock, and latch" ligand binding mechanism of the staphylococcal microbial surface component recognizing adhesive matrix molecules (MSCRAMM) SdrG.Journal of Biological Chemistry.  283:638-647. 2008
2008 Identification of novel inhibitors of bacterial surface enzyme Staphylococcus aureus Sortase A.Bioorganic and Medicinal Chemistry Letters.  18:380-385. 2008
2007 Crystal structure of ACE19, the collagen binding subdomain of Enterococus faecalis surface protein ACE.Proteins.  69:199-203. 2007
2007 Deciphering complement mechanisms: the contributions of structural biology.Molecular Immunology.  44:3809-3822. 2007
2007 An IgG-like domain in the minor pilin GBS52 of Streptococcus agalactiae mediates lung epithelial cell adhesion.Structure.  15:893-903. 2007
2007 The Enterococcus faecalis MSCRAMM ACE binds its ligand by the Collagen Hug model.Journal of Biological Chemistry.  282:19629-19637. 2007
2007 The crystal structure of C2a, the catalytic fragment of classical pathway C3 and C5 convertase of human complement.Journal of Molecular Biology.  367:224-233. 2007
2007 Crystal structure of C2a, the catalytic subunit of classical pathway C3-convertaseMolecular Immunology.  44:199-199. 2007
2005 A 'Collagen Hug' model for Staphylococcus aureus CNA binding to collagen.EMBO Journal.  24:4224-4236. 2005
2004 Anchoring of surface proteins to the cell wall of Staphylococcus aureus. A conserved arginine residue is required for efficient catalysis of sortase A.Journal of Biological Chemistry.  279:37763-37770. 2004
2004 Crystal structures of Staphylococcus aureus sortase A and its substrate complex.Journal of Biological Chemistry.  279:31383-31389. 2004
2004 Structural analysis of engineered Bb fragment of complement factor B: insights into the activation mechanism of the alternative pathway C3-convertase.Molecular Cell.  14:17-28. 2004
2004 The structure of sortase B, a cysteine transpeptidase that tethers surface protein to the Staphylococcus aureus cell wall.Structure.  12:105-112. 2004
2003 A "dock, lock, and latch" structural model for a staphylococcal adhesin binding to fibrinogen.Cell.  115:217-228. 2003
2003 A structural model for the inhibition of calpain by calpastatin: crystal structures of the native domain VI of calpain and its complexes with calpastatin peptide and a small molecule inhibitor.Journal of Molecular Biology.  328:131-146. 2003
2002 A novel variant of the immunoglobulin fold in surface adhesins of Staphylococcus aureus: crystal structure of the fibrinogen-binding MSCRAMM, clumping factor A.EMBO Journal.  21:6660-6672. 2002
2002 Crystallization and preliminary X-ray crystallographic analysis of Ace: a collagen-binding MSCRAMM from Enterococcus faecalis.BBA - Biochimica et Biophysica Acta.  1596:173-176. 2002
2001 Structural organization of the fibrinogen-binding region of the clumping factor B MSCRAMM of Staphylococcus aureus.Journal of Biological Chemistry.  276:44721-44728. 2001
2001 Structural biology of the alternative pathway convertase.Immunological Reviews.  180:123-135. 2001
2000 Structure of FKBP12.6 in complex with rapamycin.Acta Crystallographica Section D: Biological Crystallography.  56:266-271. 2000
2000 New structural motifs on the chymotrypsin fold and their potential roles in complement factor B.EMBO Journal.  19:164-173. 2000
2000 Novel fold and assembly of the repetitive B region of the Staphylococcus aureus collagen-binding surface protein.Structure.  8:67-78. 2000
2000 Mutational analysis of the primary substrate specificity pocket of complement factor B. Asp(226) is a major structural determinant for p(1)-Arg binding.Journal of Biological Chemistry.  275:378-385. 2000
1999 Erratum: Trench-shaped binding sites promote multiple classes of interactions between collagen and the adherence receptors, α1β1 integrin and Staphylococcus aureus Cna MSCRAMM (Journal of Biological Chemistry (1999) 274 (24906-24913))Journal of Biological Chemistry.  274:28836. 1999
1999 Trench-shaped binding sites promote multiple classes of interactions between collagen and the adherence receptors, alpha(1)beta(1) integrin and Staphylococcus aureus Cna MSCRAMM. (vol 274, pg 24906, 1999)Journal of Biological Chemistry.  274:28836-28836. 1999
1999 Ace is a collagen-binding MSCRAMM from Enterococcus faecalis.Journal of Biological Chemistry.  274:26939-26945. 1999
1999 Trench-shaped binding sites promote multiple classes of interactions between collagen and the adherence receptors, alpha(1)beta(1) integrin and Staphylococcus aureus cna MSCRAMM.Journal of Biological Chemistry.  274:24906-24913. 1999
1999 Structural basis of profactor D activation: from a highly flexible zymogen to a novel self-inhibited serine protease, complement factor D.EMBO Journal.  18:804-814. 1999
1999 Crystallization and preliminary X-ray analysis of B-domain fragments of a Staphylococcus aureus collagen-binding protein.Acta Crystallographica Section D: Biological Crystallography.  55:525-527. 1999
1999 Crystallization of ClfA and ClfB fragments: the fibrinogen-binding surface proteins of Staphylococcus aureus.Acta Crystallographica Section D: Biological Crystallography.  55:554-556. 1999
1999 Expression, purification, crystallization and preliminary X-ray diffraction analysis of uracil phosphoribosyltransferase of Toxoplasma gondii.Acta Crystallographica Section D: Biological Crystallography.  55:347-349. 1999
1998 Domain structure of the Staphylococcus aureus collagen adhesin.Biochemistry.  37:15423-15433. 1998
1998 Structures of native and complexed complement factor D: implications of the atypical His57 conformation and self-inhibitory loop in the regulation of specific serine protease activity.Journal of Molecular Biology.  282:1061-1081. 1998
1998 Crystallization and preliminary crystallographic investigation of porcine quinolinate phosphoribosyltransferase.Acta Crystallographica Section D: Biological Crystallography.  54:119-120. 1998
1998 The atypical serine proteases of the complement system.Advances in Immunology.  69:249-307. 1998
1997 A growing family of the Ca2+-binding proteins with five EF-hand motifs.Biochemical Journal.  328 ( Pt 2):718-720. 1997
1997 Structure of the collagen-binding domain from a Staphylococcus aureus adhesin.Nature Structural Biology.  4:833-838. 1997
1997 Crystal structure of calcium bound domain VI of calpain at 1.9 A resolution and its role in enzyme assembly, regulation, and inhibitor binding.Nature Structural Biology.  4:539-547. 1997
1997 Preliminary crystallographic study on a low molecular weight form of bacterial plasminogen activator staphylokinase.Acta Crystallographica Section D: Biological Crystallography.  53:480-481. 1997
1997 Purification, crystallization and preliminary X-ray diffraction studies of recombinant calcium-binding domain of the small subunit of porcine calpain.Acta Crystallographica Section D: Biological Crystallography.  53:474-476. 1997
1997 Refined structure of purine nucleoside phosphorylase at 2.75 A resolution.Acta Crystallographica Section D: Biological Crystallography.  53:131-142. 1997
1997 Structure of diisopropyl fluorophosphate-inhibited factor D.Acta Crystallographica Section D: Biological Crystallography.  53:143-150. 1997
1997 Site-directed mutagenesis of the phosphocholine-binding site of human C-reactive protein: role of Thr76 and Trp67.Journal of Immunology.  158:345-350. 1997
1996 Mutational analysis of the phosphocholine (pch)-binding site of human c-reactive protein (crp)Federation proceedings.  10. 1996
1996 Complement factor D, a novel serine protease.Protein Science.  5:553-564. 1996
1995 Erratum: Crystal structure of a complement factor D mutant expressing enhanced catalytic activity (Journal of Biological Chemistry (1995) 270 (24399-24405))Journal of Biological Chemistry.  270:31414. 1995
1995 Crystal structure of a complement factor D mutant expressing enhanced catalytic activity.Journal of Biological Chemistry.  270:24399-24405. 1995
1995 Catalytic role of a surface loop of the complement serine protease factor D.Journal of Immunology.  154:6073-6079. 1995
1994 Mutational analysis of the substrate binding site of human complement factor D.Biochemistry.  33:14393-14399. 1994
1994 Comparison of homology models with the experimental structure of a novel serine protease.Acta Crystallographica Section D: Biological Crystallography.  50:889-899. 1994
1994 Error detection in crystallographic models.Acta Crystallographica Section D: Biological Crystallography.  50:900-909. 1994
1994 Structures of human and porcine aldehyde reductase: an enzyme implicated in diabetic complications.Acta Crystallographica Section D: Biological Crystallography.  50:859-868. 1994
1994 Preliminary crystallographic studies on human complement pro-factor D.Journal of Molecular Biology.  235:1144-1146. 1994
1994 STRUCTURE OF HUMAN FACTOR-D A COMPLEMENT-SYSTEM PROTEIN AT 2-CENTER-DOT-0-ANGSTROM RESOLUTIONJournal of Molecular Biology.  235:695-708. 1994
1994 Structure of human factor D. A complement system protein at 2.0 A resolution.Journal of Molecular Biology.  235:695-708. 1994
1994 Recent results and new hardware developments for protein crystal growth in microgravityJournal of Crystal Growth.  135:183-195. 1994
1994 UNIQUE STRUCTURAL FEATURES OF FACTOR D, A SERINE-PROTEASE OF HUMAN-COMPLEMENTJournal of Cellular Biochemistry.  161-161. 1994
1993 Crystallization and preliminary structure determination of porcine aldehyde reductase from two crystal forms.Acta Crystallographica Section D: Biological Crystallography.  49:490-496. 1993
1991 Crystallization and preliminary X-ray investigation of factor D of human complement.Journal of Molecular Biology.  219:1-3. 1991
1991 Purification, crystallization and preliminary crystallographic analysis of porcine aldose reductase.Journal of Molecular Biology.  218:695-698. 1991
1987 Crystallization and preliminary X-ray investigation of uridine phosphorylase from Escherichia coli.Journal of Biological Chemistry.  262:2852-2853. 1987
1986 The integrase family of site-specific recombinases: regional similarities and global diversity.EMBO Journal.  5:433-440. 1986
1985 Structural similarity between legumin and vicilin storage proteins from legumes.EMBO Journal.  4:1111-1117. 1985
1985 Identification of a trpG-related glutamine amide transfer domain in Escherichia coli GMP synthetase.Journal of Biological Chemistry.  260:3350-3354. 1985
1985 Primary structural comparison of the preprohormones cholecystokinin and gastrin.FEBS Letters.  182:135-138. 1985
1984 Residue contacts in protein structures and implications for protein folding.International journal of peptide and protein research.  24:25-39. 1984
1980 Crystal and molecular structure of 2α-bromo-α-tetrahydrosantoninPerkin 2.  1116-1118. 1980
1977 Reaction of selenium sulphide with triphenyl compounds of group V elementsInorganic and Nuclear Chemistry Letters.  13:517-522. 1977

Chapter

Year Title Altmetric
2017 C2.  127-134. 2017

Full Name

  • Narayana Sthanam
  • Blazerid

  • narayana