• Dr. Mike Chen attended University of Texas and UT Health Sciences Center in Houston. He trained in general surgery at University of Florida. He completed fellowships in Transplantation and then Pediatric Surgery. He was on faculty at UMDNJ-Camden from 1996-2000. He joined the faculty at UF in Gainesville from 2000-2009. He was recruited to UAB in September, 2009. He is the Director of the Division of Pediatric Surgery and Surgeon-in-Chief of the Children’s Hospital. His focus is on providing the best clinical care possible for infants and children and to inspire young surgeons to do the same. He has a strong interest in education and mentorship.

    Dr. Chen’s clinical interests include all aspects of pediatric surgery with particular focus in anorectal malformation, Hirschsprung’s disease, bowel management, congenital anomalies, thoracic defects and minimal invasive surgery. He is also engaged in a prospective study on adolescent bariatric surgery.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2018 Systemic thrombolysis of an occlusive aortic thrombus in a neonate on extracorporeal membrane oxygenationAmerican Surgeon.  84:E372-E374. 2018
    2018 Cardiovascular risk factors after adolescent bariatric surgeryPediatrics.  141. 2018
    2017 Changes in Dietary Intake and Eating Behavior in Adolescents After Bariatric Surgery: an Ancillary Study to the Teen-LABS ConsortiumObesity Surgery.  27:3082-3091. 2017
    2017 Open versus laparoscopic approach to gastric fundoplication in children with cardiac risk factorsJournal of Surgical Research.  220:52-58. 2017
    2017 Utilization of the NSQIP-Pediatric Database in Development and Validation of a New Predictive Model of Pediatric Postoperative Wound ComplicationsJournal of The American College of Surgeons.  224:532-544. 2017
    2017 Survey on Robot-Assisted Surgical Techniques Utilization in US Pediatric Surgery FellowshipsPediatric Endosurgery and Innovative Techniques.  27:186-190. 2017
    2016 Outcome assessment of renal replacement therapy in neonatesJournal of Surgical Research.  204:34-38. 2016
    2016 Risk factors for stricture formation after esophageal atresia repairPediatric Endosurgery and Innovative Techniques.  26:393-398. 2016
    2016 Weight Loss and Health Status 3 Years after Bariatric Surgery in AdolescentsNew England Journal of Medicine.  374:113-123. 2016
    2016 Defining the role of a pediatric surgery fellowship program director: Results of a national cross-sectional surveyAmerican Surgeon.  82:E9-E12. 2016
    2015 The effort and outcomes of the Pediatric Surgery match process: Are we interviewing too many?Journal of Pediatric Surgery.  50:1954-1957. 2015
    2015 Cardiovascular risk factors in severely obese adolescents the teen longitudinal assessment of bariatric surgery (Teen-LABS) studyJAMA Pediatrics.  169:438-444. 2015
    2015 Musculoskeletal pain, self-reported physical function, and quality of life in the Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) cohortJAMA Pediatrics.  169:552-559. 2015
    2015 Routine utilization of Single-Incision Pediatric Endosurgery (SIPES): A 5-year institutional experiencePediatric Endosurgery and Innovative Techniques.  25:252-255. 2015
    2015 Single-incision pediatric endosurgery (SIPES) splenectomy: what dictates the need for additional ports?Surgical Endoscopy.  29:30-33. 2015
    2014 Extraction of esophageal foreign bodies in children: Rigid versus flexible endoscopyPediatric Surgery International.  30:417-422. 2014
    2014 Role of laparoscopy in the prevention and in the treatment of adhesionsSeminars in Pediatric Surgery.  23:353-356. 2014
    2014 Utility of immature granulocyte percentage in pediatric appendicitisJournal of Surgical Research.  190:230-234. 2014
    2013 Laparoscopic cholecystectomy for biliary dyskinesia in children: Frequency increasingJournal of Pediatric Surgery.  48:1716-1721. 2013
    2013 Single incision pediatric endosurgery (SIPES) appendectomy - Is obesity a contraindication?Journal of Pediatric Surgery.  48:1399-1404. 2013
    2013 Single-incision pediatric endosurgery for ovarian pathologyPediatric Endosurgery and Innovative Techniques.  23:291-296. 2013
    2012 Angiodysplasia (vascular malformations) of the colon presenting as an acute abdomenJournal of Pediatric Surgery.  47. 2012
    2012 Feasibility of single-incision pediatric endosurgery for treatment of appendicitis in 415 childrenPediatric Endosurgery and Innovative Techniques.  22:604-608. 2012
    2012 Laparoscopic surgery in children with congenital heart diseaseJournal of Pediatric Surgery.  47:1084-1088. 2012
    2010 American Pediatric Surgical Association New Technology Committee review on video-assisted thoracoscopic surgery for childhood cancerJournal of Pediatric Surgery.  45:2227-2233. 2010
    2010 Outcomes of treatment of childhood achalasiaJournal of Pediatric Surgery.  45:1173-1177. 2010
    2009 Position paper on laparoscopic antireflux operations in infants and children for gastroesophageal reflux diseaseJournal of Pediatric Surgery.  44:1034-1040. 2009
    2009 Equestrian injuries in childrenJournal of Pediatric Surgery.  44:148-150. 2009
    2009 Position paper on video-assisted thoracoscopic surgery as treatment of pediatric empyemaJournal of Pediatric Surgery.  44:289-293. 2009
    2008 Pediatric basal cell carcinoma: case reports and literature reviewJournal of Pediatric Surgery.  43:2277-2280. 2008
    2008 A case of dual thoracoabdominal impalement in vehicular traumaAmerican Surgeon.  74:757-760. 2008
    2008 Traumatic aortic injuries in the pediatric populationJournal of Pediatric Surgery.  43:1077-1081. 2008
    2008 Ashes, embers, and coals: Significant sources of burn-related morbidity in childrenJournal of Burn Care and Rehabilitation.  29:109-113. 2008
    2008 Mesenteric lipoblastoma: a rare location in childrenJournal of Pediatric Surgery.  43:e5. 2008
    2007 The use of Seprafilm® in pediatric surgical patientsAmerican Surgeon.  73:792-795. 2007
    2007 Salvaging the "lost peritoneum" after ventriculoatrial shunt failuresChild's Nervous System.  23:483-486. 2007
    2006 Differential response of neuroblastoma cells to TRAIL is independent of PI3K/AKTJournal of Pediatric Surgery.  41:1072-1080. 2006
    2006 Current Practice in Pediatric SurgerySurgical Clinics of North America.  86. 2006
    2006 One-year outcomes of Roux-en-Y gastric bypass for morbidly obese adolescents: A multicenter study from the Pediatric Bariatric Study GroupJournal of Pediatric Surgery.  41:137-143. 2006
    2005 VEGF-mediated survivin expression in neuroblastoma cellsJournal of Surgical Research.  127:21-28. 2005
    2004 Administration of prenatal betamethasone suppresses the adrenal-hypophyseal axis in newborns with congenital diaphragmatic herniaJournal of Pediatric Surgery.  39:1176-1182. 2004
    2004 Artificial rearing of mouse pups: Development of a mouse pup in a cup modelPediatric Research.  56:250-255. 2004
    2004 Expression of VEGF receptors in cocultured neuroblastoma cellsJournal of Surgical Research.  119:56-65. 2004
    2004 Extracorporeal membrane oxygenation combined with endovascular embolization for management of neonatal high-output cardiac failure secondary to intracranial arteriovenous fistula: Case reportJournal of Neurosurgery.  100:197-200. 2004
    2004 Animal models for intestinal tissue engineeringBiomaterials.  25:1675-1681. 2004
    2003 Neuroblastoma, apoptosis, and growth factorsAmerican Surgeon.  69:28-31. 2003
    2003 Twenty years of progress in congenital diaphragmatic hernia at the University of FloridaAmerican Surgeon.  69:45-52. 2003
    2003 Expanded application of extracorporeal membrane oxygenation in a pediatric surgery practice.Annals of Surgery.  237:766-772. 2003
    2003 Differential expression of Bcl-2 and Bax may enhance neuroblastoma survivalJournal of Pediatric Surgery.  38:486-491. 2003
    2003 VEGF receptors are differentially expressed by neuroblastoma cells in cultureJournal of Pediatric Surgery.  38:514-521. 2003
    2002 Small watercraft injuries in childrenAmerican Surgeon.  68:535-538. 2002
    2002 Caspase 3 expression is altered in a coculture model of neuroblastomaJournal of Surgical Research.  106:323-327. 2002
    2002 Insulin-like growth factor-I protects neuroblastoma against starvation-induced apoptosis and is associated with increased Bcl-2 expressionJournal of Pediatric Surgery.  37:472-476. 2002
    2002 VEGF upregulates BCL-2 expression and is associated with decreased apoptosis in neuroblastoma cellsJournal of Pediatric Surgery.  37:467-471. 2002
    2001 Gastrointestinal foreign bodiesPediatric Annals.  30:736-742. 2001
    2001 Small bowel tissue engineering using small intestinal submucosa as a scaffoldJournal of Surgical Research.  99:352-358. 2001
    2001 VEGF is upregulated in a neuroblastoma and hepatocyte coculture modelJournal of Surgical Research.  97:34-40. 2001
    2000 Neuroblastoma and hepatocyte coculture conditioned media alter apoptosisJournal of Surgical Research.  90:113-118. 2000
    2000 Free fluid on abdominal computed tomography scan after blunt trauma does not mandate exploratory laparotomy in childrenJournal of Pediatric Surgery.  35:990-993. 2000
    1999 Fas-mediated induction of hepatocyte apoptosis in a neuroblastoma and hepatocyte coculture modelJournal of Surgical Research.  84:82-87. 1999
    1999 Analysis of the costs of surgery for Hirschsprung's disease: One-stage laparoscopic pull-through versus two-stage Duhamel procedureClinical Pediatrics.  38:593-596. 1999
    1999 The effect of leukocyte infiltration on apoptosis in an in vitro thermal injury bioartificial living skin equivalent modelJournal of Burn Care and Rehabilitation.  20:374-376. 1999
    1998 Induction of apoptosis in a neuroblastoma and hepatocyte coculture modelJournal of Surgical Research.  78:123-130. 1998
    1997 Infradiaphragmatic extralobar pulmonary sequestration masquerading as an intra-abdominal, suprarenal massPediatric Surgery International.  12:529-531. 1997
    1997 Initial experience with laparoscopic-assisted pull-through for Hirschsprung's diseasePediatric Endosurgery and Innovative Techniques.  1:91-94. 1997
    1997 Laparoscopic approach for enteral nutrition in pediatric oncology patientsPediatric Endosurgery and Innovative Techniques.  1:87-90. 1997
    1997 Laparoscopic common duct exploration in a child with recurrent pancreatitis due to a primary fungus ball in the terminal common bile ductPediatric Endosurgery and Innovative Techniques.  7:63-67. 1997
    1997 Laparoscopic fundoplication in children: A superior techniquePediatric Endosurgery and Innovative Techniques.  1:71-76. 1997
    1997 Perinatal management of enteric duplication cysts of the tongueAmerican Journal of Perinatology.  14:161-163. 1997
    1997 Pilot assessment of interval laparoscopic appendectomy for treatment of perforated appendicitis in childrenPediatric Endosurgery and Innovative Techniques.  1:127-130. 1997
    1997 The role of laparoscopic lymph node sampling in childrenPediatric Endosurgery and Innovative Techniques.  1:33-38. 1997
    1996 Complications of minimal-access surgery in childrenJournal of Pediatric Surgery.  31:1161-1165. 1996
    1996 Laparoscopic evaluation and treatment of intestinal malrotation in infantsSurgical Endoscopy.  10:936-937. 1996
    1996 Tracheal hamartoma: Report of a child with a neck massJournal of Pediatric Surgery.  31:1584-1585. 1996
    1995 The Use of Minimal Access Surgery in Pediatric Trauma: A Preliminary ReportJournal of laparoendoscopic surgery.  5:295-301. 1995
    1994 Liver transplantation at the University of Florida.The Journal of the Florida Medical Association.  81:335-338. 1994
    1993 Influence of progressive tumor growth on glutamine metabolism in skeletal muscle and kidneyAnnals of Surgery.  217:655-667. 1993
    1992 Adaptive regulation in skeletal muscle glutamine metabolism in endotoxin-treated ratsJournal of Trauma.  32:600-606. 1992
    1992 Cytokine regulation of intestinal glutamine utilizationAmerican Journal of Surgery.  163:174-180. 1992
    1992 Mechanisms of accelerated hepatic glutamine efflux in the tumour-bearing ratSurgical Oncology.  1:173-182. 1992
    1991 Glutamine metabolism in cancer: Alterations in inter-organ flux and nutritional strategiesRivista Italiana di Nutrizione Parenterale ed Enterale.  9:65-71. 1991
    1991 The gut: a key organ following injury and infectionRivista Italiana di Nutrizione Parenterale ed Enterale.  9:7-14. 1991
    1991 Endotoxin and Renal Glutamine MetabolismArchives of Surgery -New York-.  126:23-27. 1991
    1991 Glutamine metabolism by the endotoxin-injured lungJournal of Trauma.  31:1068-1075. 1991
    1991 Nutritional support of the surgical oncology patientHematology/Oncology Clinics of North America.  5:125-145. 1991
    1991 The effects of endotoxin on the splanchnic metabolism of glutamine and related substratesJournal of Trauma.  31:742-752. 1991
    1991 Tumor regulation of hepatic glutamine metabolismJournal of Parenteral and Enteral Nutrition.  15:159-164. 1991
    1990 Tumor glutamine use exceeds intestinal glutamine use in cachectic tumor-bearing ratsSurgical Forum -Chicago-.  41:12-14. 1990
    1990 Glutamine nutrition: theoretical considerations and therapeutic impact.Journal of Parenteral and Enteral Nutrition.  14:237S-243S. 1990
    1990 Gut glutamine metabolism.Journal of Parenteral and Enteral Nutrition.  14. 1990


    Year Title Altmetric
    2008 Short Bowel Syndrome and Intestinal Tissue Engineering.  310-317. 2008

    Research Overview

  • anorectal malformation, Hirschsprung’s disease, bowel management, congenital anomalies, thoracic defects and minimal invasive surgery
  • Education And Training

  • Doctor of Medicine, University of Texas System : Health Science Center-Houston 1987
  • University of Florida/Shands Hospital, Internship 1988
  • University of Florida/Shands Hospital, Residency 1993
  • University of Tennessee Medical Center, Postdoctoral Fellowship 1996
  • University of Florida/Shands Hospital, Postdoctoral Fellowship 1994
  • Full Name

  • Mike Chen