Selected Publications

Academic Article

Year Title Altmetric
2018 Flow Diversion for the Treatment of Basilar Apex Aneurysms.Neurosurgery.  83:1298-1305. 2018
2018 PHASES score applied to a prospective cohort of aneurysmal subarachnoid hemorrhage patients.Journal of Clinical Neuroscience.  53:69-73. 2018
2018 Association of cystathionine beta-synthase polymorphisms and aneurysmal subarachnoid hemorrhage.Journal of Neurosurgery.  128:1771-1777. 2018
2018 Associations between endothelin polymorphisms and aneurysmal subarachnoid hemorrhage, clinical vasospasm, delayed cerebral ischemia, and functional outcome.Journal of Neurosurgery.  128:1311-1317. 2018
2018 The Use of Single Stent-Assisted Coiling in Treatment of Bifurcation Aneurysms: A Multicenter Cohort Study With Proposal of a Scoring System to Predict Complete Occlusion.Neurosurgery.  82:710-718. 2018
2018 Intra-arterial vasodilators for vasospasm following aneurysmal subarachnoid hemorrhage: a meta-analysis.Journal of NeuroInterventional Surgery.  10:380-387. 2018
2018 Pipeline embolization of posterior circulation aneurysms: a multicenter study of 131 aneurysms.Journal of Neurosurgery.  1-13. 2018
2018 Admission Systolic Blood Pressure Predicts the Number of Blood Pressure Medications at Discharge in Patients With Primary Intracerebral Hemorrhage.Neurologist.  23:60-64. 2018
2018 Association of renin-angiotensin system genetic polymorphisms and aneurysmal subarachnoid hemorrhage.Journal of Neurosurgery.  128:86-93. 2018
2018 Suboccipital Craniotomy Versus Craniectomy: A Survey of Practice Patterns.World Neurosurgery.  109:e731-e738. 2018
2017 Predictors of Incomplete Occlusion following Pipeline Embolization of Intracranial Aneurysms: Is It Less Effective in Older Patients?American Journal of Neuroradiology.  38:2295-2300. 2017
2017 The role of endothelial nitric oxide synthase -786 T/C polymorphism in cardiac instability following aneurysmal subarachnoid hemorrhage.Nitric Oxide: Biology and Chemistry.  71:52-56. 2017
2017 Dr. Norman Chater and Chater's Point.World Neurosurgery.  106:281-284. 2017
2017 Association of Plasminogen Activator Inhibitor 1 (SERPINE1) Polymorphisms and Aneurysmal Subarachnoid Hemorrhage.World Neurosurgery.  105:672-677. 2017
2017 Comparison of Stent-Assisted Coil Embolization and the Pipeline Embolization Device for Endovascular Treatment of Ophthalmic Segment Aneurysms: A Multicenter Cohort Study.World Neurosurgery.  105:206-212. 2017
2017 In Reply to the Letter to the Editor Regarding "Safety and Efficacy of Noncompliant Balloon Angioplasty for the Treatment of Subarachnoid Hemorrhage-Induced Vasospasm: A Multicenter Study".World Neurosurgery.  105:1023. 2017
2017 Pipeline Embolization Device in Treatment of 50 Unruptured Large and Giant Aneurysms.World Neurosurgery.  105:232-237. 2017
2017 Treatment of Tandem Internal Carotid Artery Aneurysms Using a Single Pipeline Embolization Device: Evaluation of Safety and Efficacy.American Journal of Neuroradiology.  38:1605-1609. 2017
2017 Permanent CSF shunting after intraventricular hemorrhage in the CLEAR III trial.Neurology.  89:355-362. 2017
2017 Reliability assessment of the Biffl Scale for blunt traumatic cerebrovascular injury as detected on computer tomography angiography.Journal of Neurosurgery.  127:32-35. 2017
2017 Corrigendum to 'Predictors of Shunt Insertion in Aneurysmal Subarachnoid Hemorrhage' [World Neurosurgery 98 (2017) 421-426].World Neurosurgery.  104:1043. 2017
2017 Associations of Endothelin Polymorphisms and Aneurysm Size at Time of Rupture.World Neurosurgery.  102:253-257. 2017
2017 Endothelin polymorphisms as a risk factor for cerebral aneurysm rebleeding following aneurysmal subarachnoid hemorrhage.Clinical Neurology and Neurosurgery.  157:65-69. 2017
2017 Associations of renin-angiotensin system genetic polymorphisms and clinical course after aneurysmal subarachnoid hemorrhage.Journal of Neurosurgery.  126:1585-1597. 2017
2017 Endothelial Nitric Oxide Synthase Polymorphism Is Associated with Delayed Cerebral Ischemia Following Aneurysmal Subarachnoid Hemorrhage.World Neurosurgery.  101:514-519. 2017
2017 External validation of the Practical Risk Chart for the prediction of delayed cerebral ischemia following aneurysmal subarachnoid hemorrhage.Journal of Neurosurgery.  126:1530-1536. 2017
2017 Impact of High-Mobility Group Box 1 Polymorphism on Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage.World Neurosurgery.  101:325-330. 2017
2017 Recrudescence of Symptoms of Remote Ischemic Stroke After a Cerebral Angiogram.World Neurosurgery.  101:814.e15-814.e17. 2017
2017 Use of Platelet Function Testing Before Pipeline Embolization Device Placement: A Multicenter Cohort Study.Stroke.  48:1322-1330. 2017
2017 Ryanodine Receptor 1 Polymorphism Is Not Associated with Aneurysmal Subarachnoid Hemorrhage or its Clinical Sequelae.World Neurosurgery.  100:190-194. 2017
2017 Trends in Transcranial Doppler Monitoring in Aneurysmal Subarachnoid Hemorrhage: A 10-Year Analysis of the Nationwide Inpatient Sample.Journal of Stroke and Cerebrovascular Diseases.  26:851-857. 2017
2017 Seizure outcomes after stereotactic radiosurgery for the treatment of cerebral arteriovenous malformations.Journal of Neurosurgery.  126:845-851. 2017
2017 Ischemic Stroke After Treatment of Intraprocedural Thrombosis During Stent-Assisted Coiling and Flow Diversion.Stroke.  48:1098-1100. 2017
2017 Thrombolytic removal of intraventricular haemorrhage in treatment of severe stroke: results of the randomised, multicentre, multiregion, placebo-controlled CLEAR III trial.Lancet.  389:603-611. 2017
2017 Predictors of Shunt Insertion in Aneurysmal Subarachnoid Hemorrhage.World Neurosurgery.  98:421-426. 2017
2017 Safety and Efficacy of Noncompliant Balloon Angioplasty for the Treatment of Subarachnoid Hemorrhage-Induced Vasospasm: A Multicenter Study.World Neurosurgery.  98:189-197. 2017
2017 A safe and effective management strategy for BCVI.Journal of Trauma and Acute Care Surgery.  82:228. 2017
2017 Blunt Traumatic Extracranial Cerebrovascular Injury and Ischemic Stroke.Cerebrovascular Diseases Extra.  7:72-83. 2017
2017 Carotid Artery Angioplasty and Stenting Without Distal Embolic Protection Devices.Neurosurgery.  80:66. 2017
2016 Association of nosocomial infections with delayed cerebral ischemia in aneurysmal subarachnoid hemorrhage.Journal of Neurosurgery.  125:1383-1389. 2016
2016 Pipeline Embolization Device for small paraophthalmic artery aneurysms with an emphasis on the anatomical relationship of ophthalmic artery origin and aneurysm.Journal of Neurosurgery.  125:1352-1359. 2016
2016 114 Treatment of Bifurcation Aneurysms Using Single Stent-Coiling With Relation to Aneurysm Configuration: A Cohort Study of Two Academic Institutions in the United States.Neurosurgery.  63 Suppl 1:148. 2016
2016 Pipeline Embolization Device for Small Intracranial Aneurysms: Evaluation of Safety and Efficacy in a Multicenter Cohort.Neurosurgery.  80:579-587. 2016
2016 Systemic Inflammatory Response Syndrome and Outcomes in Intracerebral Hemorrhage.Neurocritical Care.  25:133-140. 2016
2016 Aneurysm Study of Pipeline in an Observational Registry (ASPIRe).Interventional Neurology.  5:89-99. 2016
2016 Early Trauma-Induced Coagulopathy is Associated with Increased Ventilator-Associated Pneumonia in Spinal Cord Injury Patients.Shock.  45:502-505. 2016
2016 Vasospasm on transcranial Doppler is predictive of delayed cerebral ischemia in aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis.Journal of Neurosurgery.  124:1257-1264. 2016
2016 In reference to what is the optimal perioperative management of antiplatelet therapy?Laryngoscope.  126:E317. 2016
2016 Optical coherence tomography of traumatic aneurysms of the internal carotid artery: report of 2 cases.Journal of Neurosurgery.  124:305-309. 2016
2015 Antifibrinolytic therapy in aneurysmal subarachnoid hemorrhage increases the risk for deep venous thrombosis: A case-control study.Clinical Neurology and Neurosurgery.  139:66-69. 2015
2015 Corrective spinal surgery may be protective against stroke in patients with blunt traumatic vertebral artery occlusion.Journal of Neurosurgery: Spine.  23:665-670. 2015
2015 The clinical significance and reliability of self-reported smoking status in patients with intracranial aneurysms: a review.Clinical Neurology and Neurosurgery.  137:44-49. 2015
2015 Proposal of Venous Drainage-Based Classification System for Carotid Cavernous Fistulae With Validity Assessment in a Multicenter Cohort.Neurosurgery.  77:380-385. 2015
2015 Temporal Changes in Periprocedural Events in the Carotid Revascularization Endarterectomy Versus Stenting Trial.Stroke.  46:2183-2189. 2015
2015 Validation of a System to Predict Recanalization After Endovascular Treatment of Intracranial Aneurysms.Neurosurgery.  77:168-173. 2015
2015 Clinical Presentation, Imaging, and Management of Complications due to Neurointerventional Procedures.Seminars in Interventional Radiology.  32:98-107. 2015
2015 Carotid and vertebral injury study (CAVIS) technique for characterization of blunt traumatic aneurysms with reliability assessment.Interventional Neuroradiology.  21:255-262. 2015
2015 Access to the carotid artery bifurcation: Cadaveric study with application to nasotracheal intubation as a technique to improve access to a high carotid artery bifurcation.British Journal of Neurosurgery.  29:865-867. 2015
2015 External ventricular drain placement in the intensive care unit versus operating room: evaluation of complications and accuracy.Clinical Neurology and Neurosurgery.  128:94-100. 2015
2014 Investigating the utility of previously developed prediction scores in acute ischemic stroke patients in the stroke belt.Journal of Stroke and Cerebrovascular Diseases.  23:2001-2006. 2014
2014 Endovascular tools available for the treatment of cerebrovascular disease.Neurosurgery Clinics of North America.  25:387-394. 2014
2014 Extracranial traumatic aneurysms due to blunt cerebrovascular injury.Journal of Neurosurgery.  120:1437-1445. 2014
2014 Incidence and trends in the diagnosis of traumatic extracranial cerebrovascular injury in the nationwide inpatient sample database, 2003-2010.Journal of Neurotrauma.  31:1056-1062. 2014
2014 N-acetylcysteine (NAC) in neurological disorders: mechanisms of action and therapeutic opportunities.Brain and Behavior.  4:108-122. 2014
2014 Resolution of diminished olfactory sensation after treatment of bilateral ophthalmic segment aneurysms with flow diversion: case report.Neurosurgery.  74:E226-E229. 2014
2014 Aggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised trial.Lancet.  383:333-341. 2014
2014 CommentNeurosurgery.  75:116. 2014
2013 Guidelines for the management of acute cervical spine and spinal cord injuries: 2013 update.Neurosurgery.  60 Suppl 1:82-91. 2013
2013 Neurosurgical injuries resulting from the 2011 tornados in Alabama: the experience at the University of Alabama at Birmingham Medical Center.Journal of Neurosurgery.  118:1356-1362. 2013
2013 Rare case of bilateral vertebral artery stenosis caused by C4-5 spondylotic changes manifesting with bilateral bow hunter's syndrome.World Neurosurgery.  79:799.E1-799.E5. 2013
2013 Infection risk in neurointervention and cerebral angiography.Neurosurgery.  72:327-331. 2013
2013 Management of vertebral artery injuries following non-penetrating cervical trauma.Neurosurgery.  72 Suppl 2:234-243. 2013
2013 Real-time validation of transcranial Doppler criteria in assessing recanalization during intra-arterial procedures for acute ischemic stroke: an international, multicenter study.Stroke.  44:394-400. 2013
2013 Timing and mechanism of ischemic stroke due to extracranial blunt traumatic cerebrovascular injury.Journal of Neurosurgery.  118:397-404. 2013
2012 Detailed analysis of periprocedural strokes in patients undergoing intracranial stenting in Stenting and Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis (SAMMPRIS).Stroke.  43:2682-2688. 2012
2012 Safety and cost effectiveness of step-down unit admission following elective neurointerventional procedures.Journal of NeuroInterventional Surgery.  4:390-392. 2012
2012 Diagnosis and management of an intraorbital vascular fistula.Ophthalmic Plastic and Reconstructive Surgery.  28:e39-e41. 2012
2012 Arterial reocclusion and persistent distal occlusion after thrombus aspiration.Journal of Neuroimaging.  22:92-94. 2012
2011 CommentsNeurosurgery.  69:1271. 2011
2011 Computed tomography perfusion prognostic maps do not predict reversible and irreversible neurological dysfunction following reperfusion therapies.International Journal of Stroke.  6:544-546. 2011
2011 Pediatric traumatic carotid, vertebral and cerebral artery dissections: a review.Child's Nervous System.  27:2045-2056. 2011
2011 Velocity criteria for intracranial stenosis revisited: an international multicenter study of transcranial Doppler and digital subtraction angiography.Stroke.  42:3429-3434. 2011
2011 Stenting versus aggressive medical therapy for intracranial arterial stenosis.New England Journal of Medicine.  365:993-1003. 2011
2011 In Reply.Neurosurgery.  69:E512-E513. 2011
2011 Laparoscopic versus open insertion of the peritoneal catheter in ventriculoperitoneal shunt placement: review of 810 consecutive cases.Journal of Neurosurgery.  115:151-158. 2011
2011 In Reply.Neurosurgery.  68:E1776-E1777. 2011
2011 Rebleeding risk after treatment of ruptured intracranial aneurysms.Journal of Neurosurgery.  114:1778-1784. 2011
2011 Management of blunt extracranial traumatic cerebrovascular injury: a multidisciplinary survey of current practice.World Journal of Emergency Surgery.  6:11. 2011
2011 Safety and tolerability of early noninvasive ventilatory correction using bilevel positive airway pressure in acute ischemic stroke.Stroke.  42:1030-1034. 2011
2011 Cerebrovascular dissections: a review. Part II: blunt cerebrovascular injury.Neurosurgery.  68:517-530. 2011
2011 Cerebrovascular dissections--a review part I: Spontaneous dissections.Neurosurgery.  68:242-257. 2011
2010 Short-term antifibrinolytic therapy before early aneurysm treatment in subarachnoid hemorrhage: effects on rehemorrhage, cerebral ischemia, and hydrocephalus.Neurosurgery.  67:935-939. 2010
2010 X-configuration stent-assisted coiling.World Neurosurgery.  74:143-144. 2010
2010 Diagnostic criteria and yield of real-time transcranial Doppler monitoring of intra-arterial reperfusion procedures.Stroke.  41:695-699. 2010
2010 Hypertension may be the most important component of hyperdynamic therapy in cerebral vasospasm.Critical Care.  14:151. 2010
2009 Legacy and current understanding of the often-misunderstood Foix-Alajouanine syndrome. Historical vignette.Journal of Neurosurgery.  111:902-906. 2009
2009 Clinical experience with Matrix2 360 degrees coils in the treatment of 100 intracranial aneurysms.Surgical Neurology.  72:41-47. 2009
2009 Laparoscopic versus open approach for implantation of the peritoneal catheter during ventriculoperitoneal shunt placement.Surgical Endoscopy.  23:1449-1455. 2009
2008 Intraluminal septation of the basilar artery: incidence and potential clinical significance.Folia morphologica.  67:193-195. 2008
2007 Coil extrusion after endovascular treatment. Case illustration.Journal of Neurosurgery.  106:512. 2007
2006 Advancements in carotid stenting leading to reductions in perioperative morbidity among patients 80 years and older.Neurosurgery.  58:233-240. 2006
2005 Accelerated embolization healing of aneurysms by polyethylene terephthalate coils seeded with autologous fibroblasts: CommentsNeurosurgery.  56:1080-1081. 2005
2005 Carotid tissue levels of argatroban after direct local delivery during carotid endarterectomy to prevent perioperative cerebral embolism: CommentsNeurosurgery.  56:917-918. 2005
2005 Endovascular treatment of acute stroke.Neurosurgery Clinics of North America.  16:433-xi. 2005
2005 Deep brain stimulation for refractory obsessive-compulsive disorder.Biological Psychiatry.  57:510-516. 2005
2005 Computed tomographic perfusion in the management of aneurysmal subarachnoid hemorrhage: new application of an existent technique.Neurosurgery.  56:304-317. 2005
2005 CT perfusion cerebral blood flow imaging in neurological critical care.Neurocritical Care.  2:352-366. 2005
2004 Comparison of endovascular and surface cooling during unruptured cerebral aneurysm repair: CommentsNeurosurgery.  55:314-315. 2004
2004 Giant vertebrobasilar aneurysms: Endovascular treatment and long-term follow-up: CommentsNeurosurgery.  55:323-326. 2004
2004 Carotid perfusion CT with balloon occlusion and acetazolamide challenge test: feasibility.Radiology.  231:906-913. 2004
2004 Cerebral perfusion CT: technique and clinical applications.Radiology.  231:632-644. 2004
2004 Bivalirudin for endovascular intervention in acute ischemic stroke: case report.Neurosurgery.  54:218-222. 2004
2004 Patient selection for revascularization in cervical carotid artery disease: angioplasty and stenting vs. endarterectomy.American Heart Hospital Journal.  2:8-15. 2004
2004 The Neuroform stent, the first microcatheter-delivered stent for use in the intracranial circulation.Neurosurgery.  54:2-5. 2004
2003 Occlusion of experimental aneurysms with heparin-loaded, microporous stent grafts.Neurosurgery.  53:1397-1404. 2003
2003 Transvenous treatment of carotid cavernous and dural arteriovenous fistulae: results for 31 patients and review of the literature.Neurosurgery.  53:836-856. 2003
2003 A reappraisal of angioplasty and stenting for the treatment of vertebral origin stenosis.Neurosurgery.  53:607-614. 2003
2003 Angiogenic factors in the central nervous system.Neurosurgery.  53:639-660. 2003
2003 Results of endovascular treatment of internal carotid artery stenoses with a newly developed balloon protection catheter.Neurosurgery.  53:617-623. 2003
2003 Acceleration of aneurysm healing by controlled release of basic fibroblast growth factor with the use of polyethylene terephthalate fiber coils coated with gelatin hydrogel.Neurosurgery.  53:393-400. 2003
2003 Endovascular treatment of paraclinoid aneurysms: experience with 73 patients.Neurosurgery.  53:14-23. 2003
2003 Alcohol embolization of carotid-cavernous indirect fistulae.Neurosurgery.  52:1111-1115. 2003
2003 Effects of intraventricular infusion of vascular endothelial growth factor on cerebral blood flow, edema, and infarct volume.Acta Neurochirurgica.  145:49-53. 2003
2002 Persistent autoregulatory disturbance after angioplasty for cerebral vasospasm. A case report.Interventional Neuroradiology.  8:409-415. 2002
2002 Should interventional cardiologists treat ischemic strokes? A global perspective.Journal of Invasive Cardiology.  14:646-651. 2002
2002 Intraventricular infusion of vascular endothelial growth factor promotes cerebral angiogenesis with minimal brain edema.Neurosurgery.  50:589-598. 2002
2001 Cerebral salt wasting syndrome.Critical Care Clinics.  17:125-138. 2001
2000 Effect of hematocrit on calculation of cerebral blood flow and lambda in xenon CT.Keio Journal of Medicine.  49 Suppl 1:A36-A37. 2000
2000 Meralgia parestheticaTechniques in Neurosurgery.  6:50-56. 2000
1999 Metastatic adenocarcinoma to the brain mimicking hemorrhage: case report.Surgical Neurology.  52:46-49. 1999
1999 Adenoid cystic carcinoma metastatic to the dura: report of two cases.Journal of Neuro-Oncology.  44:267-273. 1999
1998 Abducens nerve palsy after radiofrequency rhizolysis for trigeminal neuralgia: case report.Neurosurgery.  43:623-625. 1998
1997 Indomethacin in the management of elevated intracranial pressure: a review.Journal of Neurotrauma.  14:637-650. 1997
1996 Cerebral salt wasting syndrome: a review.Neurosurgery.  38:152-160. 1996
1995 Beta amyloid is neurotoxic in hippocampal slice cultures.Neurobiology of Aging.  16:779-789. 1995
1994 Somatostatin-containing neurons in rat organotypic hippocampal slice cultures: light and electron microscopic immunocytochemistry.Hippocampus.  4:157-166. 1994


Year Title Altmetric
2013 Handbook of Cerebrovascular Disease and Neurointerventional Technique: Second Edition 2013


Year Title Altmetric
2013 Acute ischemic stroke.  757-769. 2013
2013 Cerebral angiography.  303-314. 2013
2011 Cerebral Vasospasm after Subarachnoid Hemorrhage.  207-213. 2011
2007 Carotid Endarterectomy Compared with Carotid Angioplasty and Stenting.  575-586. 2007

Research Overview

  • Cerebrovascular neurosurgery and stroke
  • Principal Investigator On

  • Private Grant  awarded by NICO CORPORATION 2018 - 2021
  • Private Grant  awarded by SUNOVION PHARMACEUTICALS, INC. 2016 - 2021
  • Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial (CREST-2)  awarded by MAYO CLINIC 2015 - 2019
  • Mechanisms of Early Recurrence in Intracranial Atherosclerotic Disease (MyRIAD)  awarded by University of Miami 2014 - 2019
  • MISTIE lll: A Phase lll, Randomized, Open-label, 500-subject Clinical Trial of Minimally Invasive Surgery Plus rt-PA in the Treatment of Intracerebral Hemorrhage  awarded by Johns Hopkins University 2013 - 2018
  • Private Grant  awarded by EDGE THERAPEUTICS, INC. 2016 - 2018
  • LARGE Aneurysm Randomized Trial: Flow Diversion Versus Traditional Endovascular Coiling Therapy  awarded by Medical University of South Carolina 2014 - 2017
  • CREST: Carotid Revascularization Endarterectomy vs. Stent Trial  awarded by Rutgers, the State University of New Jersey 2010 - 2016
  • Correlation of Cerebral Aneurysm Wall Structure on OCT Images with Flow Models of Wall Shear Stress: A Pilot Study  awarded by Brain Aneurysm Foundation 2015 - 2016
  • Clot Lysis: Evaluating Acceletrated Resolution of IVH Phase III (The CLEAR III Trial)  awarded by Johns Hopkins University 2012 - 2016
  • Private Grant  awarded by COVIDIEN 2013 - 2014
  • A Randomized Trial of Unruptured Brain Arteriovenous Malformations (ARUBA)  awarded by Columbia University 2010 - 2014
  • Private Grant  awarded by PENUMBRA, INC. 2010 - 2013
  • Stenting vs. Aggressive Medical Management for Preventing Recurrent Events in Intracranial Stenosis (SAMMPRIS)  awarded by Medical University of South Carolina 2008 - 2013
  • Interventional Management of Stroke Trial Clinical Protocol  awarded by University of Cincinnati 2011 - 2012
  • Full Name

  • Mark Harrigan