Richard Marchase

Richard Marchase
Professor Emeritus

Professor - Emeritus (P), Cell, Developmental and Integrative Biology (CDIB) , Academic Joint Departments

Selected Publications

Academic Article

Year	Title	Altmetric
2014	Changing the academic culture: Valuing patents and commercialization toward tenure and career advancement 2014
2014	Stromal interaction molecule 1 is essential for normal cardiac homeostasis through modulation of ER and mitochondrial function 2014
2014	O-GlcNAcylation of AMPA receptor GluA2 is associated with a novel form of long-term depression at hippocampal synapses 2014
2013	STIM1/Orai1-mediated SOCE: Current perspectives and potential roles in cardiac function and pathology 2013
2012	Modification of STIM1 by O-linked N-Acetylglucosamine (O-GlcNAc) attenuates store-operated calcium entry in neonatal cardiomyocytes. Journal of Biological Chemistry. 287:39094-39106. 2012
2012	Glucose deprivation-induced increase in protein O-GlcNAcylation in cardiomyocytes is calcium-dependent. Journal of Biological Chemistry. 287:34419-34431. 2012
2011	Better regulation for research universities. Issues in science and technology. 28:13-18. 2011
2010	The role of protein O-linked β-N-acetylglucosamine in mediating cardiac stress responses 2010
2010	Increased O-linked β-N-acetylglucosamine levels on proteins improves survival, reduces inflammation and organ damage 24 hours after trauma-hemorrhage in rats. Critical Care Medicine. 38:562-571. 2010
2010	Protein O-GlcNAcylation: A critical regulator of the cellular response to stress. Current Signal Transduction Therapy. 5:49-59. 2010
2009	Glucosamine improves cardiac function following trauma-hemorrhage by increased protein O-GlcNAcylation and attenuation of NF-κB signaling 2009
2008	Erratum: Peritransplant tolerance induction in macaques: Early events reflecting the unique synergy between immunotoxin and deoxyspergualin (Transplantation (1999) 68:11 (1660-1673)). Transplantation. 86:482. 2008
2008	Erratum: Tolerability and side effects of anti-CD3-immunotoxin in preclinical testing in kidney and pancreatic islet transplant recipients (Transplantation (1999) 68:2 (215-219)). Transplantation. 86:482. 2008
2008	Glucosamine protects neonatal cardiomyocytes from ischemia-reperfusion injury via increased protein O-GlcNAc and increased mitochondrial Bcl-2 2008
2008	Hexosamine biosynthesis and protein O-glycosylation: The first line of defense against stress, ischemia, and trauma. Shock. 29:431-440. 2008
2008	Overexpression of TRPC3 increases apoptosis but not necrosis in response to ischemia-reperfusion in adult mouse cardiomyocytes 2008
2008	Aging leads to increased levels of protein O-linked N-acetylglucosamine in heart, aorta, brain and skeletal muscle in Brown-Norway rats. Biogerontology. 9:139-151. 2008
2007	Glucosamine administration improves survival rate after severe hemorrhagic shock combined with trauma in rats. Shock. 28:345-352. 2007
2007	Increased O-GlcNAc levels during reperfusion lead to improved functional recovery and reduced calpain proteolysis 2007
2007	Glucosamine cardioprotection in perfused rat hearts associated with increased O-linked N-acetylglucosamine protein modification and altered p38 activation 2007
2007	Impact of Type 2 diabetes and aging on cardiomyocyte function and O-linked N-acetylglucosamine levels in the heart 2007
2007	The protective effects of PUGNAc on cardiac function after trauma-hemorrhage are mediated via increased protein O-GlcNAc levels. Shock. 27:402-408. 2007
2007	Role of protein O-linked N-acetyl-glucosamine in mediating cell function and survival in the cardiovascular system. Cardioscience. 73:288-297. 2007
2007	Glucosamine protects neonatal cardiomyocytes from ischemia-reperfusion injury via increased protein-associated O-GlcNAc 2007
2007	Glutamine-induced protection of isolated rat heart from ischemia/reperfusion injury is mediated via the hexosamine biosynthesis pathway and increased protein O-GlcNAc levels. Journal of Molecular and Cellular Cardiology. 42:177-185. 2007
2006	Glucosamine administration during resuscitation improves organ function after trauma hemorrhage. Shock. 25:600-607. 2006
2006	Increased hexosamine biosynthesis and protein O-GlcNAc levels associated with myocardial protection against calcium paradox and ischemia. Journal of Molecular and Cellular Cardiology. 40:303-312. 2006
2006	Glucosamine inhibits angiotensin II-induced cytoplasmic Ca²⁺ elevation in neonatal cardiomyocytes via protein-associated O-linked N-acetylglucosamine 2006
2005	A store-operated nonselective cation channel in human lymphocytes. Cellular and Molecular Neurobiology. 25:625-647. 2005
2005	Protein O-GlcNAc modulates motility-associated signaling intermediates in neutrophils. Journal of Biological Chemistry. 280:14579-14585. 2005
2004	Neutrophils exhibit rapid agonist-induced increases in protein-associated O-GlcNAc. Journal of Biological Chemistry. 279:45759-45765. 2004
2004	Hexosamine Pathway Is Responsible for Inhibition by Diabetes of Phenylephrine-Induced Inotropy. Diabetes. 53:1074-1081. 2004
2004	Adult rat cardiomyocytes exhibit capacitative calcium entry 2004
2004	Ca²⁺ Modulation of Ca²⁺ Release-Activated Ca ²⁺ Channels Is Responsible for the Inactivation of Its Monovalent Cation Current. Biophysical Journal. 86:805-814. 2004
2003	Regulation of Ca²⁺ release-activated Ca²⁺ channels by INAD and Ca²⁺ influx factor 2003
2002	Hyperglycemia inhibits capacitative calcium entry and hypertrophy in neonatal cardiomyocytes. Diabetes. 51:3461-3467. 2002
2002	Calnexin is associated with and induced by overexpressed human complement protein C2. Anatomical Record. 267:7-16. 2002
2002	Capacitative calcium entry contributes to nuclear factor of activated T-cells nuclear translocation and hypertrophy in cardiomyocytes. Journal of Biological Chemistry. 277:14266-14273. 2002
2001	A store-operated nonselective cation channel in lymphocytes is activated directly by CA²⁺ influx factor and diacylglycerol 2001
2000	Calcium influx factor directly activates store-operated cation channels in vascular smooth muscle cells. Journal of Biological Chemistry. 275:26158-26163. 2000
2000	Preparation and use of a photoactivatable glucose-6-phosphate analogue. Bioorganic and Medicinal Chemistry Letters. 10:535-539. 2000
2000	Loss of the major isoform of phosphoglucomutase results in altered calcium homeostasis in Saccharomyces cerevisiae. Journal of Biological Chemistry. 275:5431-5440. 2000
2000	Measuring Contributions to the Research Mission of Medical Schools. Academic Medicine. 75:304-313. 2000
1999	The inhibition of capacitative calcium entry due to ATP depletion but not due to glucosamine is reversed by staurosporine. Journal of Biological Chemistry. 274:20165-20170. 1999
1999	Efficient endocytosis of the cystic fibrosis transmembrane conductance regulator requires a tyrosine-based signal. Journal of Biological Chemistry. 274:3602-3609. 1999
1999	Calcium influx factor is synthesized by yeast and mammalian cells depleted of organellar calcium stores 1999
1998	Glucose-6-phosphate and Ca²⁺ sequestration are mutually enhanced in microsomes from liver, brain, and heart. Diabetes. 47:874-881. 1998
1997	Inhibition of capacitative Ca²⁺ entry by monosaccharides in J774 macrophages 1997
1996	A role for the glucose-6-phosphatase system in intracellular regulation of Ca²⁺ in J774 macrophages 1996
1996	Permeability to multivalent anions enhances calcuim (Ca²⁺) sequestration by rat cardiac microsomes 1996
1996	Down-regulation of secretion of human complement component C2 by the product of an alternatively spliced C2 messenger RNA. Journal of Immunology. 156:4901-4908. 1996
1996	Regulation of intracellular calcium is closely linked to glucose metabolism in J774 macrophages. Cell Calcium. 20:361-371. 1996
1995	Hyperglycemia alters cytoplasmic Ca²⁺ responses to capacitative Ca²⁺ influx in rat aortic smooth muscle cells. American Journal of Physiology. 269. 1995
1995	The posttranslational modification of phosphoglucomutase is regulated by galactose induction and glucose repression in Saccharomyces cerevisiae. Journal of Bacteriology. 177:3087-3094. 1995
1994	The glycosylation of phosphoglucomutase is modulated by carbon source and heat shock in Saccharomyces cerevisiae. Journal of Biological Chemistry. 269:27143-27148. 1994
1994	Rapid endocytosis of the cystic fibrosis transmembrane conductance regulator chloride channel 1994
1994	Role of NO production in NMDA receptor-mediated neurotransmitter release in cerebral cortex. Science. 263:973-977. 1994
1994	The Addition of Glucose‐1‐Phosphate to the Cytoplasmic Glycoprotein Phosphoglucomutase Is Modulated by Intracellular Calcium in PC12 Cells and Rat Cortical Synaptosomes. Journal of Neurochemistry. 62:456-464. 1994
1993	Isolation and expression of a rat liver cDNA encoding phosphoglucomutase. Gene. 133:261-266. 1993
1993	Glycogen contains phosphodiester groups that can be introduced by UDPglucose:glycogen glucose 1-phosphotransferase. FEBS Letters. 329:263-267. 1993
1993	Cell surface labeling of CFTR in T84 cells. American Journal of Physiology. 264. 1993
1993	Phosphoglucomutase in Saccharomyces cerevisiae is a cytoplasmic glycoprotein and the acceptor for a Glc-phosphotransferase. Journal of Biological Chemistry. 268:8341-8349. 1993
1992	Gangliosides as modulators of cell function. American Journal of Physiology. 262. 1992
1992	Identification of a membrane protein from T84 cells using antibodies made against a DIDS-binding peptide. American Journal of Physiology. 262. 1992
1991	β-phosphorothioate analogs of nucleotide sugars are resistant to hydrolytic degradation and utilized efficiently by glycosyltransferases. Analytical Biochemistry. 197:40-46. 1991
1991	Receptor synthesis and routing to the plasma membrane. American Journal of the Medical Sciences. 302:238-243. 1991
1990	Parafusin, an exocytic-sensitive phosphoprotein, is the primary acceptor for the glucosylphosphotransferase in Paramecium tetraurelia and rat liver 1990
1990	Relative accessibility of N-acetylglucosamine in trimers of the adenovirus types 2 and 5 fiber proteins. Journal of Virology. 64:5317-5323. 1990
1990	Resolution of phosphoglucomutase and the 62-kDA acceptor for the glucosylphosphotransferase. Molecular cell biology research communications : MCBRC. 280:122-129. 1990
1989	An α-glucose-1-phosphate phosphodiesterase is present in rat liver cytosol. Journal of Biological Chemistry. 264:20540-20546. 1989
1988	Cell surface expression of 4β‐galactosyltransferase accompanies rat parotid gland acinar cell transition to growth. Journal of Cellular Biochemistry. 36:453-465. 1988
1988	Localization of the glucose phosphotransferase to a cytoplasmically accessible site on intracellular membranes.. Journal of Biological Chemistry. 263:17792-17797. 1988
1987	Glucose-1-phosphate containing glycoproteins and interneuronal adhesion. Integrative and Comparative Biology. 27:179-187. 1987
1987	The β-phosphoro[³⁵S]thioate analogue of UDP-Glc is efficiently utilized by the glucose phosphotransferase and is relatively resistant to hydrolytic degradation 1987
1987	Glucose-1-phosphotransferase and N-acetylglucosamine-1-phosphotransferase have distinct acceptor specificities. Journal of Biological Chemistry. 262:4377-4381. 1987
1987	Isoproterenol-mediated parotid gland hypertrophy is inhibited by effectors of 4β-galactosyltransferase. Journal of Biological Chemistry. 262:11706-11713. 1987
1986	Glucose phosphotransferase and intracelular trafficking 1986
1984	Ontogeny of the basal lamina in the sea urchin embryo. Developmental Biology. 103:235-245. 1984
1984	Phosphoglucose-containing glycoproteins in intracellular trafficking and neuronal recognition.. Advances in Experimental Medicine and Biology. 181:161-173. 1984
1984	Three peptides recognizing mannose-6-phosphate-α1-glucose 1984
1982	A Possible Role for Ligatin and the Phosphoglycoproteins It Binds in Calcium‐Dependent Retinal Cell Adhesion. Journal of Cellular Biochemistry. 18:461-468. 1982
1982	A UDP-glucose:Glycoprotein glucose-1-phosphotransferase in embryonic chicken neural retina. Cell. 31:739-748. 1982
1982	Brain Ligatin: A Membrane Lectin That Binds Acetylcholinesterase. Journal of Cellular Biochemistry. 18:447-459. 1982
1982	Calcium‐Dependent and Calcium‐Independent Adhesive Mechanisms Are Present During Initial Binding Events of Neural Retina Cells. Journal of Cellular Biochemistry. 18:469-478. 1982
1982	Retinal ligatin recognizes glycoproteins bearing oligosaccharides terminating in phosphodiester-linked glucose. Cell. 28:813-820. 1982
1981	Distribution of anionic sites on surfaces of retinal cells: A study using cationized ferritin. Journal of Structural Biology. 76:96-106. 1981
1981	Intercellular recognition: Quantitation of initial binding events 1981
1981	Ligatin from embryonic chick neural retina inhibits retinal cell adhesion. Developmental Biology. 86:250-255. 1981
1979	Ligatin from embryonic chick neural retina 1979
1979	Separation of ectoderm and endoderm from sea urchin pluteus larvae and demonstration of germ layer-specific antigens. Developmental Biology. 71:289-296. 1979
1978	Glycosyltransferase activities in developing chick embryos: potential roles in cell recognition and migration. Birth defects original article series. 14:317-326. 1978
1978	The potential roles for ganglioside GM2 and GM1 synthetase in retinotectal specificity.. Symposia of the Society for Experimental Biology. 32:261-274. 1978
1978	Properties of a double gradient model for retinotectal specificity. Progress in clinical and biological research. VOL.23:637-645. 1978
1977	Biochemical investigations of retinotectal specificity.. Progress in clinical and biological research. 15:73-79. 1977
1977	Biochemical investigations of retinotectal adhesive specificity 1977
1976	Intercellular adhesive specificity 1976
1975	A molecular approach to retinotectal specificity 1975
1975	A molecular approach to retinotectal specificity.. Novartis Foundation symposium. 0:315-341. 1975
1973	Adhesive recognition and retinotectal specificity 1973

Chapter

Year	Title	Altmetric
2013	Phosphoglucomutase Is a Cytoplasmic Glycoprotein Implicated in the Regulated Secretory Pathway. 289-292. 2013
1984	Gene Expression and Cell-Cell Interactions in the Developing Nervous System 1984
1984	Receptor for Glycoproteins with Phosphorylated Oligosaccharides. 261-313. 1984