Richard Marchase

Richard Marchase
Professor Emeritus

Professor - Emeritus (P), Cell, Developmental and Integrative Biology (CDIB) , Academic Joint Departments

Selected Publications

Academic Article

Year	Title	Altmetric
2014	Changing the academic culture: Valuing patents and commercialization toward tenure and career advancement 2014
2014	Stromal interaction molecule 1 is essential for normal cardiac homeostasis through modulation of ER and mitochondrial function 2014
2014	O-GlcNAcylation of AMPA receptor GluA2 is associated with a novel form of long-term depression at hippocampal synapses 2014
2013	STIM1/Orai1-mediated SOCE: Current perspectives and potential roles in cardiac function and pathology 2013
2012	Modification of STIM1 by O-linked N-Acetylglucosamine (O-GlcNAc) attenuates store-operated calcium entry in neonatal cardiomyocytes. Journal of Biological Chemistry. 287:39094-39106. 2012
2012	Glucose deprivation-induced increase in protein O-GlcNAcylation in cardiomyocytes is calcium-dependent. Journal of Biological Chemistry. 287:34419-34431. 2012
2011	Better regulation for research universities 2011
2010	The role of protein O-linked β-N-acetylglucosamine in mediating cardiac stress responses 2010
2010	Increased O-linked β-N-acetylglucosamine levels on proteins improves survival, reduces inflammation and organ damage 24 hours after trauma-hemorrhage in rats. Critical Care Medicine. 38:562-571. 2010
2010	Protein O-GlcNAcylation: A critical regulator of the cellular response to stress. Current Signal Transduction Therapy. 5:49-59. 2010
2009	Glucosamine improves cardiac function following trauma-hemorrhage by increased protein O-GlcNAcylation and attenuation of NF-κB signaling 2009
2008	Erratum: Peritransplant tolerance induction in macaques: Early events reflecting the unique synergy between immunotoxin and deoxyspergualin (Transplantation (1999) 68:11 (1660-1673)). Transplantation. 86:482. 2008
2008	Erratum: Tolerability and side effects of anti-CD3-immunotoxin in preclinical testing in kidney and pancreatic islet transplant recipients (Transplantation (1999) 68:2 (215-219)). Transplantation. 86:482. 2008
2008	Glucosamine protects neonatal cardiomyocytes from ischemia-reperfusion injury via increased protein O-GlcNAc and increased mitochondrial Bcl-2 2008
2008	Hexosamine biosynthesis and protein O-glycosylation: The first line of defense against stress, ischemia, and trauma. Shock. 29:431-440. 2008
2008	Overexpression of TRPC3 increases apoptosis but not necrosis in response to ischemia-reperfusion in adult mouse cardiomyocytes 2008
2008	Aging leads to increased levels of protein O-linked N-acetylglucosamine in heart, aorta, brain and skeletal muscle in Brown-Norway rats. Biogerontology. 9:139-151. 2008
2007	Glucosamine administration improves survival rate after severe hemorrhagic shock combined with trauma in rats. Shock. 28:345-352. 2007
2007	Increased O-GlcNAc levels during reperfusion lead to improved functional recovery and reduced calpain proteolysis 2007
2007	Glucosamine cardioprotection in perfused rat hearts associated with increased O-linked N-acetylglucosamine protein modification and altered p38 activation 2007
2007	Impact of Type 2 diabetes and aging on cardiomyocyte function and O-linked N-acetylglucosamine levels in the heart 2007
2007	The protective effects of PUGNAc on cardiac function after trauma-hemorrhage are mediated via increased protein O-GlcNAc levels. Shock. 27:402-408. 2007
2007	Role of protein O-linked N-acetyl-glucosamine in mediating cell function and survival in the cardiovascular system. Cardiovascular Research. 73:288-297. 2007
2007	Glucosamine protects neonatal cardiomyocytes from ischemia-reperfusion injury via increased protein-associated O-GlcNAc 2007
2007	Glutamine-induced protection of isolated rat heart from ischemia/reperfusion injury is mediated via the hexosamine biosynthesis pathway and increased protein O-GlcNAc levels. Journal of Molecular and Cellular Cardiology. 42:177-185. 2007
2006	Glucosamine administration during resuscitation improves organ function after trauma hemorrhage. Shock. 25:600-607. 2006
2006	Increased hexosamine biosynthesis and protein O-GlcNAc levels associated with myocardial protection against calcium paradox and ischemia. Journal of Molecular and Cellular Cardiology. 40:303-312. 2006
2006	Glucosamine inhibits angiotensin II-induced cytoplasmic Ca²⁺ elevation in neonatal cardiomyocytes via protein-associated O-linked N-acetylglucosamine 2006
2005	A store-operated nonselective cation channel in human lymphocytes. Cellular and Molecular Neurobiology. 25:625-647. 2005
2005	Protein O-GlcNAc modulates motility-associated signaling intermediates in neutrophils. Journal of Biological Chemistry. 280:14579-14585. 2005
2004	Neutrophils exhibit rapid agonist-induced increases in protein-associated O-GlcNAc. Journal of Biological Chemistry. 279:45759-45765. 2004
2004	Hexosamine Pathway Is Responsible for Inhibition by Diabetes of Phenylephrine-Induced Inotropy. Diabetes. 53:1074-1081. 2004
2004	Adult rat cardiomyocytes exhibit capacitative calcium entry 2004
2004	Ca²⁺ Modulation of Ca²⁺ Release-Activated Ca ²⁺ Channels Is Responsible for the Inactivation of Its Monovalent Cation Current. Biophysical Journal. 86:805-814. 2004
2003	Regulation of Ca²⁺ release-activated Ca²⁺ channels by INAD and Ca²⁺ influx factor 2003
2002	Hyperglycemia inhibits capacitative calcium entry and hypertrophy in neonatal cardiomyocytes. Diabetes. 51:3461-3467. 2002
2002	Calnexin is associated with and induced by overexpressed human complement protein C2. Anatomical Record. 267:7-16. 2002
2002	Capacitative calcium entry contributes to nuclear factor of activated T-cells nuclear translocation and hypertrophy in cardiomyocytes. Journal of Biological Chemistry. 277:14266-14273. 2002
2001	A store-operated nonselective cation channel in lymphocytes is activated directly by CA²⁺ influx factor and diacylglycerol 2001
2000	Calcium influx factor directly activates store-operated cation channels in vascular smooth muscle cells. Journal of Biological Chemistry. 275:26158-26163. 2000
2000	Preparation and use of a photoactivatable glucose-6-phosphate analogue. Bioorganic and Medicinal Chemistry Letters. 10:535-539. 2000
2000	Loss of the major isoform of phosphoglucomutase results in altered calcium homeostasis in Saccharomyces cerevisiae. Journal of Biological Chemistry. 275:5431-5440. 2000
2000	Measuring Contributions to the Research Mission of Medical Schools. Academic Medicine. 75:304-313. 2000
1999	The inhibition of capacitative calcium entry due to ATP depletion but not due to glucosamine is reversed by staurosporine. Journal of Biological Chemistry. 274:20165-20170. 1999
1999	Efficient endocytosis of the cystic fibrosis transmembrane conductance regulator requires a tyrosine-based signal. Journal of Biological Chemistry. 274:3602-3609. 1999
1999	Calcium influx factor is synthesized by yeast and mammalian cells depleted of organellar calcium stores 1999
1998	Glucose-6-phosphate and Ca²⁺ sequestration are mutually enhanced in microsomes from liver, brain, and heart. Diabetes. 47:874-881. 1998
1997	Inhibition of capacitative Ca²⁺ entry by monosaccharides in J774 macrophages. The FASEB Journal. 11. 1997
1996	A role for the glucose-6-phosphatase system in intracellular regulation of Ca²⁺ in J774 macrophages. The FASEB Journal. 10. 1996
1996	Permeability to multivalent anions enhances calcuim (Ca²⁺) sequestration by rat cardiac microsomes. The FASEB Journal. 10. 1996
1996	Down-regulation of secretion of human complement component C2 by the product of an alternatively spliced C2 messenger RNA. Journal of Immunology. 156:4901-4908. 1996
1996	Regulation of intracellular calcium is closely linked to glucose metabolism in J774 macrophages. Cell Calcium. 20:361-371. 1996
1995	Hyperglycemia alters cytoplasmic Ca²⁺ responses to capacitative Ca²⁺ influx in rat aortic smooth muscle cells 1995
1995	The posttranslational modification of phosphoglucomutase is regulated by galactose induction and glucose repression in Saccharomyces cerevisiae. Journal of Bacteriology. 177:3087-3094. 1995
1994	The glycosylation of phosphoglucomutase is modulated by carbon source and heat shock in Saccharomyces cerevisiae. Journal of Biological Chemistry. 269:27143-27148. 1994
1994	Rapid endocytosis of the cystic fibrosis transmembrane conductance regulator chloride channel 1994
1994	Role of NO production in NMDA receptor-mediated neurotransmitter release in cerebral cortex. Science. 263:973-977. 1994
1994	The Addition of Glucose‐1‐Phosphate to the Cytoplasmic Glycoprotein Phosphoglucomutase Is Modulated by Intracellular Calcium in PC12 Cells and Rat Cortical Synaptosomes. Journal of Neurochemistry. 62:456-464. 1994
1993	Isolation and expression of a rat liver cDNA encoding phosphoglucomutase. Gene. 133:261-266. 1993
1993	Glycogen contains phosphodiester groups that can be introduced by UDPglucose:glycogen glucose 1-phosphotransferase. FEBS Letters. 329:263-267. 1993
1993	Cell surface labeling of CFTR in T84 cells. American Journal of Physiology. 264. 1993
1993	Phosphoglucomutase in Saccharomyces cerevisiae is a cytoplasmic glycoprotein and the acceptor for a Glc-phosphotransferase. Journal of Biological Chemistry. 268:8341-8349. 1993
1992	Gangliosides as modulators of cell function. American Journal of Physiology. 262. 1992
1992	Identification of a membrane protein from T84 cells using antibodies made against a DIDS-binding peptide. American Journal of Physiology. 262. 1992
1991	β-phosphorothioate analogs of nucleotide sugars are resistant to hydrolytic degradation and utilized efficiently by glycosyltransferases. Analytical Biochemistry. 197:40-46. 1991
1991	Receptor synthesis and routing to the plasma membrane. American Journal of the Medical Sciences. 302:238-243. 1991
1990	Parafusin, an exocytic-sensitive phosphoprotein, is the primary acceptor for the glucosylphosphotransferase in Paramecium tetraurelia and rat liver 1990
1990	Relative accessibility of N-acetylglucosamine in trimers of the adenovirus types 2 and 5 fiber proteins. Journal of Virology. 64:5317-5323. 1990
1990	Resolution of phosphoglucomutase and the 62-kDA acceptor for the glucosylphosphotransferase. Archives of Biochemistry and Biophysics. 280:122-129. 1990
1989	An α-glucose-1-phosphate phosphodiesterase is present in rat liver cytosol. Journal of Biological Chemistry. 264:20540-20546. 1989
1988	Cell surface expression of 4β‐galactosyltransferase accompanies rat parotid gland acinar cell transition to growth. Journal of Cellular Biochemistry. 36:453-465. 1988
1988	Localization of the glucose phosphotransferase to a cytoplasmically accessible site on intracellular membranes.. Journal of Biological Chemistry. 263:17792-17797. 1988
1987	Glucose-1-phosphate containing glycoproteins and interneuronal adhesion 1987
1987	The β-phosphoro[³⁵S]thioate analogue of UDP-Glc is efficiently utilized by the glucose phosphotransferase and is relatively resistant to hydrolytic degradation 1987
1987	Glucose-1-phosphotransferase and N-acetylglucosamine-1-phosphotransferase have distinct acceptor specificities. Journal of Biological Chemistry. 262:4377-4381. 1987
1987	Isoproterenol-mediated parotid gland hypertrophy is inhibited by effectors of 4β-galactosyltransferase. Journal of Biological Chemistry. 262:11706-11713. 1987
1986	Glucose phosphotransferase and intracelular trafficking 1986
1984	Ontogeny of the basal lamina in the sea urchin embryo. Developmental Biology. 103:235-245. 1984
1984	Phosphoglucose-containing glycoproteins in intracellular trafficking and neuronal recognition.. Advances in Experimental Medicine and Biology. 181:161-173. 1984
1984	Three peptides recognizing mannose-6-phosphate-α1-glucose. The FASEB Journal. 43. 1984
1982	A Possible Role for Ligatin and the Phosphoglycoproteins It Binds in Calcium‐Dependent Retinal Cell Adhesion. Journal of Cellular Biochemistry. 18:461-468. 1982
1982	A UDP-glucose:Glycoprotein glucose-1-phosphotransferase in embryonic chicken neural retina. Cell. 31:739-748. 1982
1982	Brain Ligatin: A Membrane Lectin That Binds Acetylcholinesterase. Journal of Cellular Biochemistry. 18:447-459. 1982
1982	Calcium‐Dependent and Calcium‐Independent Adhesive Mechanisms Are Present During Initial Binding Events of Neural Retina Cells. Journal of Cellular Biochemistry. 18:469-478. 1982
1982	Retinal ligatin recognizes glycoproteins bearing oligosaccharides terminating in phosphodiester-linked glucose. Cell. 28:813-820. 1982
1981	Distribution of anionic sites on surfaces of retinal cells: A study using cationized ferritin 1981
1981	Intercellular recognition: Quantitation of initial binding events 1981
1981	Ligatin from embryonic chick neural retina inhibits retinal cell adhesion. Developmental Biology. 86:250-255. 1981
1979	Ligatin from embryonic chick neural retina 1979
1979	Separation of ectoderm and endoderm from sea urchin pluteus larvae and demonstration of germ layer-specific antigens. Developmental Biology. 71:289-296. 1979
1978	Glycosyltransferase activities in developing chick embryos: potential roles in cell recognition and migration. Birth defects original article series. 14:317-326. 1978
1978	The potential roles for ganglioside GM2 and GM1 synthetase in retinotectal specificity. 1978
1978	Properties of a double gradient model for retinotectal specificity. Progress in clinical and biological research. VOL.23:637-645. 1978
1977	Biochemical investigations of retinotectal specificity.. Progress in clinical and biological research. 15:73-79. 1977
1977	Biochemical investigations of retinotectal adhesive specificity 1977
1976	Intercellular adhesive specificity 1976
1975	A molecular approach to retinotectal specificity 1975
1975	A molecular approach to retinotectal specificity.. Ciba Foundation symposium. 0:315-341. 1975
1973	Adhesive recognition and retinotectal specificity 1973

Chapter

Year	Title	Altmetric
2013	Phosphoglucomutase Is a Cytoplasmic Glycoprotein Implicated in the Regulated Secretory Pathway. 289-292. 2013
1984	Gene Expression and Cell-Cell Interactions in the Developing Nervous System 1984
1984	Receptor for Glycoproteins with Phosphorylated Oligosaccharides. 261-313. 1984