Selected Publications

Academic Article

Year Title Altmetric
2018 Wnt receptor Frizzled 8 is a target of ERG in prostate cancerProstate.  78:1311-1320. 2018
2018 Detection of BRAF V600E mutations with next-generation sequencing in infarcted thyroid carcinomas after fine-needle aspirationAmerican Journal of Clinical Pathology.  150:177-185. 2018
2018 Single molecule mtDNA fiber FISH for analyzing numtogenesisAnalytical Biochemistry.  552:45-49. 2018
2018 miR-34a regulates expression of the stathmin-1 oncoprotein and prostate cancer progressionCell Growth and Differentiation.  16:1125-1137. 2018
2018 Hsp70 and gama-Semino protein as possible prognostic marker of prostate cancerFrontiers in Bioscience.  23:1987-2000. 2018
2018 Prostate cancer health disparities: An immuno-biological perspectiveCancer Letters.  414:153-165. 2018
2017 Bromoethylindole (BEI-9) redirects NF-κB signaling induced by camptothecin and TNFα to promote cell death in colon cancer cellsApoptosis.  22:1553-1563. 2017
2017 Prolonged exposure of resveratrol induces reactive superoxide species–independent apoptosis in murine prostate cellsTumor Biology.  39:1-10. 2017
2017 Label-free detection of DNA hybridization with a compact LSPR-based fiber-optic sensorAnalyst.  142:1974-1981. 2017
2017 Functional consequence of the p53 codon 72 polymorphism in colorectal cancerOncotarget.  8:76574-76586. 2017
2017 Molecular characterization of pro-metastatic functions of β4- integrin in colorectal cancerOncotarget.  8:92333-92345. 2017
2017 Prognostic value of loss of heterozygosity and sub-cellular localization of SMAD4 varies with tumor stage in colorectal cancerOncotarget.  8:20198-20212. 2017
2017 Resveratrol induces mitochondria-mediated, caspaseindependent apoptosis in murine prostate cancer cellsOncotarget.  8:20895-20908. 2017
2016 Molecular Biomarkers of Colorectal Cancer and Cancer Disparities: Current Status and PerspectiveCurrent Colorectal Cancer Reports.  12:332-344. 2016
2016 A comparison of 12-gene colon cancer assay gene expression in African American and Caucasian patients with stage II colon cancerBMC Cancer.  16. 2016
2016 Mucins and associated glycan signatures in colon adenoma-carcinoma sequence: Prospective pathological implication(s) for early diagnosis of colon cancerCancer Letters.  374:304-314. 2016
2016 Targeting Hsp70: A possible therapy for cancerCancer Letters.  374:156-166. 2016
2016 Association between Hepatitis C Virus Infection, p53 Phenotypes, and Gene Variants of Adenomatous Polyposis Coli in Hepatocellular Carcinomas.J Dig Dis Hepatol.  2016. 2016
2015 Antitumor activity of melinjo (Gnetum gnemon L.) seed extract in human and murine tumor models in vitro and in acolon-26 tumor-bearing mouse model in vivoCancer Medicine.  4:1767-1780. 2015
2015 3-(2-bromoethyl)-indole inhibits the growth of cancer cells and NF-κB activationOncology Reports.  34:495-503. 2015
2015 Clinical implications of rabphillin-3A-like gene alterations in breast cancerPLoS ONE.  10. 2015
2015 IND-2, a pyrimido[1″,2″:1,5]pyrazolo[3,4-b]quinoline derivative, circumvents multi-drug resistance and causes apoptosis in colon cancer cellsBioorganic and Medicinal Chemistry.  23:602-611. 2015
2015 Nanomagnetic levitation three-dimensional cultures of breast and colorectal cancersJournal of Surgical Research.  194:319-326. 2015
2015 Nef-M1, a peptide antagonist of CXCR4, inhibits tumor angiogenesis and epithelial-to-mesenchymal transition in colon and breast cancersOncotarget.  6:27763-27777. 2015
2014 Disparities in cervical cancer mortality rates as determined by the longitudinal hyperbolastic mixed-effects type II modelPLoS ONE.  9. 2014
2014 Variable NF-κB pathway responses in colon cancer cells treated with chemotherapeutic drugsBMC Cancer.  14. 2014
2014 A New Robust Method for Nonlinear Regression.Journal of Biometrics and Biostatistics.  5:211. 2014
2014 Robust Logistic and Probit Methods for Binary and Multinomial Regression.Journal of Biometrics and Biostatistics.  5. 2014
2013 The Chemokine CXCL8 in Carcinogenesis and Drug Response.ISRN Oncology.  2013:859154. 2013
2013 Clinical implications of microRNAs in cancerStain technology.  88:388-396. 2013
2013 Post-transcriptional processing of genetic information and its relation to cancerStain technology.  88:365-372. 2013
2013 The prognostic value of MicroRNAs varies with patient race/ethnicity and stage of colorectal cancerClinical Cancer Research.  19:3955-3965. 2013
2013 Nef-M1, a CXCR4 Peptide Antagonist, Enhances Apoptosis and Inhibits Primary Tumor Growth and Metastasis in Breast Cancer.Journal of Cancer Therapy.  4:898-906. 2013
2013 Selective COX-2 inhibitor (celecoxib) decreases cellular growth in prostate cancer cell lines independent of p53Stain technology.  88:38-46. 2013
2013 Socioeconomic status, p53 abnormalities, and colorectal cancerJournal of Gastrointestinal Oncology.  4:40-44. 2013
2012 Pseudoangiomatous stromal hyperplasia (PASH) of the breast: A series of 24 patientsBreast Journal.  18:242-247. 2012
2012 Prognostic significance and gene expression profiles of p53 mutations in microsatellite-stable Stage III colorectal adenocarcinomasPLoS ONE.  7. 2012
2012 Characterization of the colorectal cancer-associated enhancer MYC-335 at 8q24: The role of rs67491583Cancer Genetics.  205:25-33. 2012
2012 Dual-mode interaction between quercetin and DNA-damaging drugs in cancer cellsAnticancer Research.  32:61-71. 2012
2012 MiRNAs are stable in colorectal cancer archival tissue blocksFrontiers in bioscience (Elite edition).  4 E:1937-1940. 2012
2011 Development and progression of colorectal neoplasiaCancer Biomarkers.  9:235-265. 2011
2011 The biology of incipient, pre-invasive or intraepithelial neoplasiaCancer Biomarkers.  9:21-39. 2011
2011 Translational pathology of neoplasiaCancer Biomarkers.  9:7-20. 2011
2011 Development and independent validation of a prognostic assay for stage ii colon cancer using formalin-fixed paraffin-embedded tissueJournal of Clinical Oncology.  29:4620-4626. 2011
2011 Evaluation of lymph node numbers for adequate staging of Stage II and III colon cancerJournal of Hematology & Oncology.  4. 2011
2011 Erratum: Development of combination tapered fiber-optic biosensor dip probe for quantitative estimation of interleukin-6 in serum samples (Journal of Biomedical Optics (2010) 15 (067005))Journal of Biomedical Optics.  16. 2011
2010 Bax expression is a candidate prognostic and predictive marker of colorectal cancer.Journal of Gastrointestinal Oncology.  1:76-89. 2010
2010 Development of combination tapered fiber-optic biosensor dip probe for quantitative estimation of interleukin-6 in serum samplesJournal of Biomedical Optics.  15. 2010
2010 Standards for immunohistochemical imaging: A protein reference device for biomarker quantitationJournal of Histochemistry and Cytochemistry.  58:1005-1014. 2010
2010 MiRNAs as biomarkers for management of patients with colorectal cancerBiomarkers in Medicine.  4:761-770. 2010
2010 Prognostic value of mucin 4 expression in colorectal adenocarcinomasCancer.  116:3577-3586. 2010
2010 Comparison of the predictive qualities of three prognostic models of colorectal cancerFrontiers in bioscience (Elite edition).  2 E:849-856. 2010
2010 Quantitative estimation of IL-6 in serum/plasma samples using a rapid and cost-effective fiber optic dip-probeProgress in Biomedical Optics and Imaging - Proceedings of SPIE.  7559. 2010
2010 Smad signaling is required to maintain epigenetic silencing during breast cancer progressionCancer Research.  70:968-978. 2010
2009 Effect of comorbidity and body mass index on the survival of African-American and Caucasian patients with colon cancerCancer.  115:5798-5806. 2009
2009 HIV Nef-M1 effects on colorectal cancer growth in tumor-induced spleens and hepatic metastasisMolecular and Cellular Pharmacology.  1:85-91. 2009
2009 Combined effects of formalin fixation and tissue processing on immunorecognition Fixation effects on immunostainingStain technology.  84:223-247. 2009
2009 Combined effects of formalin fixation and tissue processing on immunorecognition.Stain technology.  84:223-247. 2009
2009 Furthering the evidence-based management of dermatologic effects of EGFR inhibitor therapyCurrent Colorectal Cancer Reports.  5:179-181. 2009
2009 Predictive capacity of three comorbidity indices in estimating mortality after surgery for colon cancerJournal of Clinical Oncology.  27:4339-4345. 2009
2009 Detection of Merkel cell polyomavirus in formalin-fixed, paraffin-embedded tissue of Merkel cell carcinoma and its correlation with prognosis.Journal of Clinical Oncology.  27:6027. 2009
2009 Prognostic significance of VDR, DKK-1, and DKK-4 expression in colorectal cancer.Journal of Clinical Oncology.  27:e15047. 2009
2009 Prognostic significance of p53 Codon 72 polymorphism differs with race in colorectal adenocarcinomaClinical Cancer Research.  15:2406-2416. 2009
2009 Immunohistochemical expression of rabphilin -3A-like (Noc2) in normal and tumor tissues of human endocrine pancreasStain technology.  84:39-45. 2009
2008 Clinical significance of a novel single nucleotide polymorphism in the 5′ untranslated region of the Rabphillin-3A-Like gene in colorectal adenocarcinomaFrontiers in Bioscience.  13:1050-1061. 2008
2008 Lynch syndrome in women less than 50 years of age with endometrial cancerObstetrics and Gynecology.  111:1161-1166. 2008
2008 p53 nuclear accumulation and Bcl-2 expression in contiguous adenomatous components of colorectal adenocarcinomas predict aggressive tumor behaviorJournal of Histochemistry and Cytochemistry.  56:305-312. 2008
2007 Comparison of predicted probabilities of proportional hazards regression and linear discriminant analysis methods using a colorectal cancer molecular biomarker databaseCancer Informatics.  3:115-122. 2007
2007 Understanding racial differences in colorectal cancer aids in individualized medicineFuture Oncology.  3:235-241. 2007
2007 Methionine inhibits cellular growth dependent on the p53 status of cellsAmerican Journal of Surgery.  193:274-283. 2007
2007 African-American and Caucasian disparities in colorectal cancer mortality and survival by data source: An epidemiologic reviewCancer Biomarkers.  3:301-313. 2007
2007 Predicting 5-year survival of colorectal carcinoma patients using data mining methods.AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium.  907. 2007
2006 Biomarkers in Diagnosis of pancreatic carcinoma in fine-needle aspirates.American Journal of Clinical Pathology.  126:572-579. 2006
2006 Genetic and epigenetic biomarkers in cancer diagnosis and identifying high risk populationsCritical Reviews in Oncology/Hematology.  60:9-18. 2006
2006 Mucinous expression in benign and neoplastic glandular lesions of the uterine cervixArchives of Pathology and Laboratory Medicine.  130:1510-1515. 2006
2006 Phenotypic expression of Bax is a predictive marker of 5-fluorouracil treatment in colorectal cancer.Journal of Clinical Oncology.  24:3605. 2006
2006 Biomarkers in diagnosis of pancreatic carcinoma in fine-needle aspirates: A translational research applicationAmerican Journal of Clinical Pathology.  126:572-579. 2006
2005 The need for review and understanding of SELDI/MALDI mass spectroscopy data prior to analysisCancer Informatics.  1:86-97. 2005
2005 Keynote review: Recent advances in biomarkers for cancer diagnosis and treatmentDrug Discovery Today.  10:965-976. 2005
2005 High-grade tumor differentiation is an indicator of poor prognosis in African Americans with colonic adenocarcinomasCancer.  103:2163-2170. 2005
2005 Recurrence and survival predictive value of phenotypic expression of Bcl-2 varies with tumor stage of colorectal adenocarcinomaCancer Biomarkers.  1:241-250. 2005
2004 Postsurgical disparity in survival between African Americans and Caucasians with colonic adenocarcinoma [2] (multiple letters)Cancer.  101:2899-2900. 2004
2004 Postsurgical disparity in survival between African Americans and Caucasians with colonic adenocarcinomaCancer.  101:66-76. 2004
2004 Prognostic Significance of p27 kip-1 Expression in Colorectal Adenocarcinomas Is Associated with Tumor StageClinical Cancer Research.  10:1743-1752. 2004
2003 MUC1 and MUC2 Expression in Pancreatic Ductal Carcinoma Obtained by Fine-Needle AspirationCancer.  99:365-371. 2003
2003 The efficacy of 9-Cis-retinoic acid (aliretinoin) as a chemopreventive agent for cervical dysplasia: Results of a randomized double-blind clinical trialCancer Epidemiology, Biomarkers and Prevention.  12:114-119. 2003
2003 Nuclear accumulation of p53 is a potential marker for the development of squamous cell lung cancer in smokersChest.  123:181-186. 2003
2002 Differential expression of growth factors in squamous cell carcinoma and precancerous lesions of the lungClinical Cancer Research.  8:734-744. 2002
2002 Quantitation of cytosine deaminase mRNA by real-time reverse transcription polymerase chain reaction: A sensitive method for assessing 5-fluorocytosine toxicity in VitroAnalytical Biochemistry.  301:189-199. 2002
2002 Molecular staging of colorectal cancer in African-American and caucasian patients using phenotypic expression of p53, Bcl-2, MUC-1 and p27kip-1International Journal of Cancer.  97:403-409. 2002
2001 Altered subcellular localization of Suppressin, a novel inhibitor of cell-cycle entry, is an independent prognostic factor in colorectal adenocarcinomasClinical Cancer Research.  7:3495-3503. 2001
2001 Nuclear accumulation of p53 is a potential marker for the development of squamous cell lung cancer in smokers.Federation proceedings.  15:A249-A249. 2001
2001 Molecular characterization of colorectal neoplasia in translational researchArchives of Pathology and Laboratory Medicine.  125:91-98. 2001
2001 Molecular differences in mucoepidermoid carcinoma and adenoid cystic carcinoma of the major salivary glandsLaryngoscope.  111:1373-1378. 2001
2000 Racial differences in the prognostic usefulness of MUC1 and MUC2 in colorectal adenocarcinomasClinical Cancer Research.  6:4017-4025. 2000
2000 BC1-2 expression is associated with improved prognosis in patients with distal colorectal adenocarcinomasInternational Journal of Cancer.  89:423-430. 2000
2000 Bcl-2 expression is associated with improved prognosis in patients with distal colorectal adenocarcinomas.International Journal of Cancer.  89:423-430. 2000
2000 Elevated expression of fatty acid synthase (FASE) in squamous cell cancer of the lung.Federation proceedings.  14:A789-A789. 2000
2000 Immunohistochemical evaluation of global DNA methylation: Comparison with in vitro radiolabeled methyl incorporation assayStain technology.  75:251-258. 2000
2000 The expression of Ep-CAM (17-1A) in squamous cell cancers of the lungHuman Pathology.  31:482-487. 2000
2000 The expression of fatty acid synthase (FASE) is an early event in the development and progression of squamous cell carcinoma of the lungHuman Pathology.  31:1068-1073. 2000
1999 Androgenic regulation of growth factor and growth factor receptor expression in the CWR22 model of prostatic adenocarcinomaInternational Journal of Cancer.  82:424-429. 1999
1999 Evaluation of biomarker modulation by fenretinide in prostate cancer patientsEuropean Urology.  35:429-438. 1999
1999 Changes in cyclin dependent kinase inhibitors p21 and p27 during the castration induced regression of the CWR22 model of prostatic adenocarcinomaJournal of Urology, The.  161:945-949. 1999
1999 Ep-CAM levels in prostatic adenocarcinoma and prostatic intraepithelial neoplasiaJournal of Urology, The.  162:1462-1466. 1999
1998 Nuclear accumulation of p53 in colorectal adenocarcinoma prognostic importance differs with race and location of the tumorCancer.  83:2456-2467. 1998
1997 Prognostic significance of Bcl-2 expression and p53 nuclear accumulation in colorectal adenocarcinomaInternational Journal of Cancer.  74:346-358. 1997
1997 Re: loss of tumor marker-immunostaining intensity on stored paraffin slides of breast cancer.JNCI: Journal of the National Cancer Institute.  89:585-586. 1997
1997 The use of biomarker expression to characterize neoplastic processesStain technology.  72:96-104. 1997


Year Title Altmetric
2012 Development and progression of colorectal neoplasia.  235-265. 2012

Education And Training

  • Doctor of Philosophy in Zoology / Animal Biology, Osmania University 1987
  • Full Name

  • Upender Manne