• Dr. Luz M. Reyes obtained her Master’s degree in Genetics at the National University of Colombia in Bogota, Colombia. She completed her Ph.D. in Molecular Genetics at the North Carolina State University, Raleigh, NC.

    Genetics, Cell Biology, and Molecular Biology constitute the main areas that Dr. Reyes has explored as a scientist. Her research has been focused on the genetic characterization of the swine class I and class II MHC complex. Currently she is working in the creation of knockout pigs using Cas 9 nuclease and guide RNAs system.

    Prior to coming to the University of Alabama at Birmingham, she worked as a Research Assistant Professor at the Department of Surgery, School of Medicine at Indiana University.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2018 Xenoantigen Deletion and Chemical Immunosuppression Can Prolong Renal Xenograft Survival.Annals of Surgery.  268:564-573. 2018
    2018 CRISPR/Cas and recombinase-based human-to-pig orthotopic gene exchange for xenotransplantation.Journal of Surgical Research.  229:28-40. 2018
    2018 Examining the Biosynthesis and Xenoantigenicity of Class II Swine Leukocyte Antigen Proteins.Journal of Immunology.  200:2957-2964. 2018
    2017 Swine Leukocyte Antigen Class II Is a Xenoantigen.Transplantation.  102:249-254. 2017
    2017 Humoral Reactivity of Renal Transplant-Waitlisted Patients to Cells From GGTA1/CMAH/B4GalNT2, and SLA Class I Knockout Pigs.Transplantation.  101:e86-e92. 2017
    2016 Silencing porcine genes significantly reduces human-anti-pig cytotoxicity profiles: an alternative to direct complement regulation.Transgenic Research.  25:751-759. 2016
    2015 Reduced human platelet uptake by pig livers deficient in the asialoglycoprotein receptor 1 protein.Xenotransplantation.  22:203-210. 2015
    2014 Creating class I MHC-null pigs using guide RNA and the Cas9 endonuclease.Journal of Immunology.  193:5751-5757. 2014
    2014 Characterization of swine leucocyte antigen alleles in a crossbred pig to be used in xenotransplant studies.Tissue Antigens.  84:484-488. 2014
    2013 Efficient selection of Gal-knockout pig cells for somatic cell nuclear transfer.Journal of Surgical Research.  184:e37-e42. 2013
    2013 Double knockout pigs deficient in N-glycolylneuraminic acid and galactose α-1,3-galactose reduce the humoral barrier to xenotransplantation.Xenotransplantation.  20:27-35. 2013
    2011 Gene targeting and cloning in pigs using fetal liver derived cells.Journal of Surgical Research.  171:e223-e229. 2011
    2011 Primary porcine Kupffer cell phagocytosis of human platelets involves the CD18 receptor.Transplantation.  92:739-744. 2011
    2011 ASGR1 expressed by porcine enriched liver sinusoidal endothelial cells mediates human platelet phagocytosis in vitro.Xenotransplantation.  18:245-251. 2011
    2010 The fate of human platelets perfused through the pig liver: implications for xenotransplantation.Xenotransplantation.  17:350-361. 2010

    Education And Training

  • Doctor of Science in Horticultural Science, North Carolina State University
  • Full Name

  • Luz Reyes