Selected Publications

Academic Article

Year Title Altmetric
2019 An R2 statistic for covariance model selection in the linear mixed modelJournal of Applied Statistics.  46:164-184. 2019
2019 Out-of-Clinic Sympathetic Activity Is Increased in Patients With Masked Uncontrolled Hypertension.Hypertension.  73:132-141. 2019
2018 Impact of bladder cancer on health-related quality of life.BJU International.  121:549-557. 2018
2018 Assessing responsiveness over time of the PROMIS® pediatric symptom and function measures in cancer, nephrotic syndrome, and sickle cell disease.Quality of Life Research.  27:249-257. 2018
2017 A test of separate hypotheses for comparing linear mixed models with non nested fixed effectsCommunications in Statistics - Theory and Methods.  46:5487-5500. 2017
2017 Early extubation in pediatric heart surgery across a spectrum of case complexity: Impact on hospital length of stay and chest tube days.Progress in Pediatric Cardiology.  45:63-68. 2017
2017 An R2statistic for fixed effects in the generalized linear mixed modelJournal of Applied Statistics.  44:1086-1105. 2017
2017 Novel baseline predictors of adverse events during oral immunotherapy in children with peanut allergy.Journal of Allergy and Clinical Immunology.  139:882-888.e5. 2017
2016 Responsiveness of PROMIS® Pediatric Measures to Hospitalizations for Sickle Pain and Subsequent Recovery.Medical and Pediatric Oncology.  63:1038-1045. 2016
2016 Visit-to-Visit Variability in Blood Pressure Is Related to Late-Life Cognitive Decline.Hypertension.  68:106-113. 2016
2016 The Performance and Association Between Patient-reported and Performance-based Measures of Physical Functioning in Research on Individuals with Arthritis.Journal of Rheumatology.  43:131-137. 2016
2015 Dietary Patterns and Cognitive Decline Among Chinese Older Adults.Epidemiology.  26:758-768. 2015
2015 Outcomes of pediatric patients with abdominal sepsis requiring surgery and extracorporeal membrane oxygenation using the Extracorporeal Life Support Organization database.American Surgeon.  81:245-251. 2015
2015 Weighing projections of physical decline in lung cancer surgery decisions.American Journal of the Medical Sciences.  349:61-66. 2015
2014 Fish intake is associated with slower cognitive decline in Chinese older adults.Journal of Nutrition.  144:1579-1585. 2014
2014 An analysis of 24-h ambulatory blood pressure monitoring data using orthonormal polynomials in the linear mixed model.Blood Pressure Monitoring.  19:153-163. 2014
2014 An intervention to decrease stigma in young adults with sickle cell disease.Western Journal of Nursing Research.  36:599-619. 2014
2014 Kronecker product linear exponent AR(1) correlation structures for multivariate repeated measures.PLoS ONE.  9:e88864. 2014
2014 Patient characteristics associated with favorable perceptions of patient-provider communication in early-stage lung cancer treatment.Journal of Health Communication.  19:532-544. 2014
2014 Public attitudes about lung cancer: stigma, support, and predictors of support.Journal of Multidisciplinary Healthcare.  7:293-300. 2014
2014 Separability tests for high-dimensional, low sample size multivariate repeated measures data.Journal of Applied Statistics.  41:2450-2461. 2014
2013 Correction.Annals of Thoracic Surgery.  96:1532. 2013
2013 A circular LEAR correlation structure for cyclical longitudinal data.Statistical Methods in Medical Research.  22:296-306. 2013
2013 Preferences for arthritis interventions: identifying similarities and differences among African Americans and whites with osteoarthritis.Arthritis Care and Research.  65:203-211. 2013
2013 Quality of life among long-term survivors of non-Hodgkin lymphoma: a follow-up study.Journal of Clinical Oncology.  31:272-279. 2013
2012 Management of stage IIIA non-small cell lung cancer by thoracic surgeons in North America.Annals of Thoracic Surgery.  94:922-926. 2012
2012 Early-life soy exposure and age at menarche.Paediatric and Perinatal Epidemiology.  26:163-175. 2012
2012 Fixed and random effects modelsWiley Interdisciplinary Reviews: Computational Statistics.  4:181-190. 2012
2011 Early-life soy exposure and gender-role play behavior in children.Environmental Health Perspectives.  119:1811-1816. 2011
2011 Post-traumatic stress symptoms in long-term non-Hodgkin's lymphoma survivors: does time heal?Journal of Clinical Oncology.  29:4526-4533. 2011
2011 Avoiding bias in mixed model inference for fixed effects.Statistics in Medicine.  30:2696-2707. 2011
2011 Disparities in postacute rehabilitation care for stroke: an analysis of the state inpatient databases.Archives of Physical Medicine and Rehabilitation.  92:1220-1229. 2011
2011 Disparities in post-acute rehabilitation care for joint replacement.Arthritis Care and Research.  63:1020-1030. 2011
2011 Estimating variance components and random effects using the box-cox transformation in the linear mixed modelCommunications in Statistics - Theory and Methods.  40:515-531. 2011
2010 Patient preferences for stroke rehabilitation.Topics in Stroke Rehabilitation.  17:394-400. 2010
2010 A linear exponent AR(1) family of correlation structures.Statistics in Medicine.  29:1825-1838. 2010
2010 Factors associated with decisions to undergo surgery among patients with newly diagnosed early-stage lung cancer.Journal of the American Medical Association.  303:2368-2376. 2010
2010 Genetic and functional characterization of putative Ras/Raf interaction inhibitors in C. elegans and mammalian cells.Journal of Molecular Signaling.  5:2. 2010
2010 Real longitudinal data analysis for real people: building a good enough mixed model.Statistics in Medicine.  29:504-520. 2010
2009 Ror2, a developmentally regulated kinase, promotes tumor growth potential in renal cell carcinoma.Oncogene.  28:2513-2523. 2009
2008 Nursing home deficiency resolution: Are the states following federal guidelines?Hallym International Journal of Aging: Gerontological Research, Policies and Programs in the New Millennium.  10:1-21. 2008
2008 An R2 statistic for fixed effects in the linear mixed model.Statistics in Medicine.  27:6137-6157. 2008
2008 Fixed-effect variable selection in linear mixed models using R2statisticsComputational Statistics and Data Analysis.  52:1896-1907. 2008
2008 Nursing home deficiencies: an exploratory study of interstate variations in regulatory activity.Journal of Aging and Social Policy.  20:398-413. 2008
2007 Statistical tests with accurate size and power for balanced linear mixed models.Statistics in Medicine.  26:3639-3660. 2007
2007 Testing transformations for the linear mixed modelComputational Statistics and Data Analysis.  51:4297-4307. 2007
2007 Continuity of care and hypertension control in a university-based practice.Ethnicity and Disease.  17:693-698. 2007
2006 Comparing United States versus international medical school graduate physicians who serve African- American and White elderly.Health Services Research.  41:2155-2181. 2006
2006 Extending the Box-Cox transformation to the linear mixed modelJournal of the Royal Statistical Society: Series A.  169:273-288. 2006
2006 A method for fitting regression splines with varying polynomial order in the linear mixed model.Statistics in Medicine.  25:513-527. 2006
2005 Physician-patient racial concordance, continuity of care, and patterns of care for hypertension.American Journal of Public Health.  95:2186-2190. 2005
2005 Naïve T cells are maintained in the periphery during the first 3 months of acute HIV-1 infection: implications for analysis of thymus function.Journal of Clinical Immunology.  25:462-472. 2005
2005 Prediction of 3-year developmental outcomes from sleep development over the preterm periodInfant Behavior and Development.  28:118-131. 2005
2005 Effect of olanzapine on body composition and energy expenditure in adults with first-episode psychosis.American Journal of Psychiatry.  162:118-123. 2005
2004 Obesity and type 2 diabetes mellitus: a population-based study of adolescents.Journal of Pediatric Endocrinology and Metabolism.  17:1633-1640. 2004
2003 Nontuberculous mycobacteria. I: multicenter prevalence study in cystic fibrosis.American Journal of Respiratory and Critical Care Medicine.  167:828-834. 2003
2003 Phosphatidylethanolamine N-methyltransferase (PEMT) knockout mice have hepatic steatosis and abnormal hepatic choline metabolite concentrations despite ingesting a recommended dietary intake of choline.Biochemical Journal.  370:987-993. 2003
2002 Deficiency in methionine, tryptophan, isoleucine, or choline induces apoptosis in cultured cells.Journal of Nutrition.  132:1840-1847. 2002
2002 Protease inhibitors are associated with a slowed progression of HIV-related renal diseases.Clinical Nephrology.  57:336-341. 2002
2002 HIV infection: treatment outcomes in older and younger adults.Journal of the American Geriatrics Society.  50:603-607. 2002
2002 Randomized study of temporary hemodialysis catheters.Life support systems : the journal of the European Society for Artificial Organs.  25:40-44. 2002
2002 Screening for diabetes in an outpatient clinic population.Journal of General Internal Medicine.  17:23-28. 2002
2001 Linear equality constraints in the general linear mixed model.Biometrics.  57:1185-1190. 2001
2001 Results of a randomized, prospective, multicenter trial of mycophenolate mofetil versus azathioprine in the prevention of acute lung allograft rejection.Transplantation.  71:1772-1776. 2001
2001 Immunologic profile of human immunodeficiency virus-infected patients during viral remission and relapse on antiretroviral therapy.Journal of Infectious Diseases.  183:1522-1525. 2001
2001 A prospective evaluation of health-related quality of life after ileal pouch anal anastomosis for ulcerative colitis.American Journal of Gastroenterology.  96:1480-1485. 2001
2001 Improving the reliability of stroke subgroup classification using the Trial of ORG 10172 in Acute Stroke Treatment (TOAST) criteria.Stroke.  32:1091-1098. 2001
2001 Identification of higher risk thin melanomas should be based on Breslow depth not Clark level IV.Cancer.  91:983-991. 2001
2001 Effect of thymectomy on human peripheral blood T cell pools in myasthenia gravis.Journal of Immunology.  166:2808-2817. 2001
2001 Impact of sodium and ultrafiltration profiling on hemodialysis-related symptoms.Journal of the American Society of Nephrology.  12:151-156. 2001
2000 Depression and other determinants of values placed on current health state by stroke patients: evidence from the VA Acute Stroke (VASt) study.Stroke.  31:2603-2609. 2000
2000 Modern statistical techniques for the analysis of longitudinal data in biomedical research.Pediatric Pulmonology.  30:330-344. 2000
2000 Significance of blood stream infection after lung transplantation: analysis in 176 consecutive patients.Transplantation.  69:2360-2366. 2000
2000 Racial variation in initial stroke severity.Stroke.  31:563-567. 2000
2000 A randomized trial of 3,4-diaminopyridine in Lambert-Eaton myasthenic syndrome.Neurology.  54:603-607. 2000
2000 Predictive Value of Single-Fiber Electromyography in the Extensor Digitorum Communis Muscle of Patients with Ocular Myasthenia Gravis: A Retrospective StudyJournal of Clinical Neuromuscular Disease.  2:6-9. 2000
1999 Attitudes of African Americans toward participation in medical researchJournal of Applied Social Psychology.  29:552-574. 1999
1998 Temporal organization of sleep-wake states in preterm infants.Developmental Psychobiology.  33:257-269. 1998
1998 Measurement error in dietary data: implications for the epidemiologic study of the diet-disease relationship.European Journal of Clinical Nutrition.  52:722-727. 1998
1998 Modeling development of sleep-wake behaviors. II. Results of two cohorts of preterms.Physiology and Behavior.  63:319-328. 1998
1998 Modeling development of sleep-wake behaviors: I. Using the mixed general linear model.Physiology and Behavior.  63:311-318. 1998
1997 Acute safety and effects on mucociliary clearance of aerosolized uridine 5′-triphosphate ± amiloride in normal human adultsPediatric Pulmonology.  23:319. 1997
1997 Longitudinal analysis of pulmonary function decline in patients with cystic fibrosis.Journal of Pediatrics.  131:809-814. 1997
1997 Airway deposition and clearance and systemic pharmacokinetics of amiloride following aerosolization with an ultrasonic nebulizer to normal airways.Chest.  112:1283-1290. 1997
1996 Acute safety and effects on mucociliary clearance of aerosolized uridine 5'-triphosphate +/- amiloride in normal human adults.American Journal of Respiratory and Critical Care Medicine.  154:217-223. 1996
1996 Relief of the 'air hunger' of breathholding. A role for pulmonary stretch receptors.Respiration Physiology.  103:221-232. 1996
1995 A controlled study of adenoviral-vector-mediated gene transfer in the nasal epithelium of patients with cystic fibrosis.New England Journal of Medicine.  333:823-831. 1995
1995 Relief of distress of breathholding: separate effects of expiration and inspiration.Respiration Physiology.  101:41-46. 1995
1995 Effect of measurement error in testing separate linear modelsJournal of Statistical Computation and Simulation.  52:205-216. 1995
1995 Errors-in-variables and the Box-Cox transformationComputational Statistics and Data Analysis.  20:131-140. 1995
1994 Beyond couvade: pregnancy symptoms in couples with a history of infertility.Health Care for Women International.  15:537-548. 1994
1994 Pathologic apnea and brief respiratory pauses in preterm infants: relation to sleep state.Nursing Research.  43:293-300. 1994
1994 An alternative approach to estimation in the functional measurement error problemCommunications in Statistics - Theory and Methods.  23:1651-1664. 1994
1994 Approximating Fisher’s information for the functional measurement error modelJournal of Applied Statistics.  21:205-219. 1994
1994 The Fowler breathholding study revisited: continuous rating of respiratory sensation.Respiration Physiology.  95:53-66. 1994
1992 Nontuberculous mycobacteria in adult patients with cystic fibrosis.Chest.  102:70-75. 1992
1991 Aerosolized amiloride as treatment of cystic fibrosis lung disease: a pilot study.Advances in Experimental Medicine and Biology.  290:119-128. 1991
1990 Aerosolized amiloride for the treatment of lung disease in cystic fibrosis.New England Journal of Medicine.  323:996-998. 1990
1990 A pilot study of aerosolized amiloride for the treatment of lung disease in cystic fibrosis.New England Journal of Medicine.  322:1189-1194. 1990
1990 Aerosolized amiloride for the treatment of lung disease in cystic fibrosis (Reply)New England Journal of Medicine.  323:997-998. 1990


Year Title Altmetric
2007 8 Mixed Models.  Ed. 27.  2007
2000 35 Bridging the biostatistics-epidemiology gap.  Ed. 18.  2000


Year Title Altmetric
2011 Mixed Models.  146-173. 2011

Education And Training

  • Doctor of Philosophy in Biostatistics, University of North Carolina System : Chapel Hill
  • Full Name

  • Lloyd Edwards
  • Fax

  • 205-975-2540
  • Blazerid

  • ljedward