Positions

Selected Publications

Academic Article

Year Title Altmetric
2019 Chymase uptake by cardiomyocytes results in myosin degradation in cardiac volume overload 2019
2017 The therapeutic potential of CFTR modulators for COPD and other airway diseases 2017
2017 Desmin loss and mitochondrial damage precede left ventricular systolic failure in volume overload heart failure 2017
2016 Codon bias and the folding dynamics of the cystic fibrosis transmembrane conductance regulator 2016
2016 Increased fibroblast chymase production mediates procollagen autophagic digestion in volume overload 2016
2016 A synonymous codon change alters the drug sensitivity of ΔF508 cystic fibrosis transmembrane conductance regulator 2016
2015 Volume overload induces autophagic degradation of procollagen in cardiac fibroblasts 2015
2015 ▵F508 CFTR surface stability is regulated by DAB2 and CHIP-mediated ubiquitination in post-endocytic compartments 2015
2015 Characterization of intracellular aggresomes by fluorescent microscopy 2015
2014 Rescuing ΔF508 CFTR with trimethylangelicin, A dual-acting corrector and potentiator 2014
2013 The silent codon change I507-ATC→ATT contributes to the severity of the AF508 CFTR channel dysfunction 2013
2012 Dab2 is a key regulator of endocytosis and post-endocytic trafficking of the cystic fibrosis transmembrane conductance regulator 2012
2011 ARFGAP1 promotes AP-2-dependent endocytosis 2011
2011 CFTR expression regulation by the unfolded protein response 2011
2011 Human cytomegalovirus UL97 kinase prevents the deposition of mutant protein aggregates in cellular models of Huntington's disease and Ataxia 2011
2010 Targets for cystic fibrosis therapy: Proteomic analysis and correction of mutant cystic fibrosis transmembrane conductance regulator 2010
2009 ER-associated complexes (ERACs) containing aggregated cystic fibrosis transmembrane conductance regulator (CFTR) are degraded by autophagy 2009
2005 Transcriptional repression and cell death induced by nuclear aggregates of non-polyglutamine protein 2005
2005 Nuclear aggresomes form by fusion of PML-associated aggregates 2005
2004 The Ca2+ homeostasis defects in a pgm2Δ strain of Saccharomyces cerevisiae are caused by excessive vacuolar Ca2+ uptake mediated by the Ca2+-ATPase Pmc1p 2004
2003 Traffic-independent function of the Sar1p/COPII machinery in proteasomal sorting of the cystic fibrosis transmembrane conductance regulator 2003
2002 Intracellular glucose 1-phosphate and glucose 6-phosphate levels modulate Ca2+ homeostasis in Saccharomyces cerevisiae 2002
2000 Loss of the major isoform of phosphoglucomutase results in altered calcium homeostasis in Saccharomyces cerevisiae 2000
1999 The vacuolar Ca2+/H+ exchanger Vcx1p/Hum1p tightly controls cytosolic Ca2+ levels in S. cerevisiae 1999
1999 The Golgi apparatus plays a significant role in the maintenance of Ca2+ homeostasis in the vps33Δ vacuolar biogenesis mutant of saccharomyces cerevisiae 1999
1995 The efficiency of translation termination is determined by a synergistic interplay between upstream and downstream sequences in Saccharomyces cerevisiae 1995
1995 The posttranslational modification of phosphoglucomutase is regulated by galactose induction and glucose repression in Saccharomyces cerevisiae 1995

Full Name

  • Lianwu Fu