Positions

Selected Publications

Academic Article

Year Title Altmetric
2016 TREM-like transcript 2 is stored in human neutrophil primary granules and is up-regulated in response to inflammatory mediators.Journal of Leukocyte Biology.  100:177-184. 2016
2016 Biomedical science postdocs: an end to the era of expansion.Federation proceedings.  30:41-44. 2016
2016 Family history of hematologic malignancies and risk of multiple myeloma: differences by race and clinical features.Cancer Causes and Control.  27:81-91. 2016
2014 Murine marginal zone B cells play a role in Vibrio cholerae LPS antibody responses.Pathogens and Disease.  70:153-157. 2014
2014 Putting PhDs to work: career planning for today's scientist.CBE : Life Sciences Education.  13:49-53. 2014
2013 The actin and tetraspanin networks organize receptor nanoclusters to regulate B cell receptor-mediated signaling.Immunity.  38:461-474. 2013
2013 Lymphotoxin α1β2 expression on B cells is required for follicular dendritic cell activation during the germinal center response.European Journal of Immunology.  43:348-359. 2013
2012 Erratum: Writing a first grant proposal (Nature Immunology (2011) 13 (105-108))Nature Immunology.  13:621. 2012
2012 Writing a first grant proposal.Nature Immunology.  13:105-108. 2012
2011 Differential expression of the adaptor protein HSH2 controls the quantitative and qualitative nature of the humoral response.Journal of Immunology.  187:3565-3577. 2011
2011 TLT2 potentiates neutrophil antibacterial activity and chemotaxis in response to G protein-coupled receptor-mediated signaling.Journal of Immunology.  187:2346-2355. 2011
2011 Marginal zone B cells regulate antigen capture by marginal zone macrophages.Journal of Immunology.  186:2172-2181. 2011
2006 Trem-like transcript 2 is expressed on cells of the myeloid/granuloid and B lymphoid lineage and is up-regulated in response to inflammation.Journal of Immunology.  176:6012-6021. 2006
2006 Expression of the adaptor protein hematopoietic Src homology 2 is up-regulated in response to stimuli that promote survival and differentiation of B cells.Journal of Immunology.  176:4163-4172. 2006
2005 The adaptor protein HSH2 attenuates apoptosis in response to ligation of the B cell antigen receptor complex on the B lymphoma cell line, WEHI-231.Journal of Biological Chemistry.  280:3507-3515. 2005
2003 The B cell coreceptor CD22 associates with AP50, a clathrin-coated pit adapter protein, via tyrosine-dependent interaction.Journal of Immunology.  170:3534-3543. 2003
2002 AP2 adaptor complex-dependent internalization of CD5: differential regulation in T and B cells.Journal of Immunology.  168:5612-5620. 2002
2002 Evaluating function of transmembrane protein tyrosine phosphatase CD148 in lymphocyte biology.Immunologic Research.  26:153-166. 2002
2001 CD45 function is regulated by an acidic 19-amino acid insert in domain II that serves as a binding and phosphoacceptor site for casein kinase 2.Journal of Immunology.  166:7208-7218. 2001
2001 The role of the protein tyrosine phosphatase CD45 in regulation of B lymphocyte activation.International Reviews of Immunology.  20:713-738. 2001
2000 Regulation of MHC class II signal transduction by the B cell coreceptors CD19 and CD22.Journal of Immunology.  165:5588-5596. 2000
2000 Signal transduction and the coordination of B lymphocyte development and function I. Transduction of BCR signals from the cell membrane to the nucleus. IntroductionCurrent Topics in Microbiology and Immunology.  245:V-X. 2000
2000 Signal transduction via the B-cell antigen receptor: the role of protein tyrosine kinases and protein tyrosine phosphatases.Current Topics in Microbiology and Immunology.  245:1-51. 2000
1999 Analysis of tyrosine phosphorylation-dependent interactions between stimulatory effector proteins and the B cell co-receptor CD22.Journal of Biological Chemistry.  274:18769-18776. 1999
1999 CD45 regulates tyrosine phosphorylation of CD22 and its association with the protein tyrosine phosphatase SHP-1.Journal of Immunology.  162:5278-5286. 1999
1998 Major histocompatibility class II-mediated signal transduction is regulated by the protein-tyrosine phosphatase CD45.Journal of Biological Chemistry.  273:11970-11979. 1998
1998 Association of MHC class II molecules with transmembrane protein(s) is required for the formation of a competent signaling complex in B cellsFederation proceedings.  12. 1998
1998 CD45 regulates the interaction between CD22 and SHP-1 in B cellsFederation proceedings.  12. 1998
1998 Interaction of AP50 with the cytoplasmic domain of murine CD22.2Federation proceedings.  12. 1998
1997 Kinase-independent potentiation of B cell antigen receptor-mediated signal transduction by the protein tyrosine kinase Src.Journal of Immunology.  159:4823-4833. 1997
1997 Recruitment and phosphorylation of SH2-containing inositol phosphatase and Shc to the B-cell Fc gamma immunoreceptor tyrosine-based inhibition motif peptide motif.Molecular and Cellular Biology.  17:4305-4311. 1997
1997 The role of CD45 in signal transduction.Advances in Immunology.  66:1-65. 1997
1996 Yersinia enterocolitica envelope proteins that are crossreactive with the thyrotropin receptor (TSHR) also have B-cell mitogenic activity.Journal of Autoimmunity.  9:509-516. 1996
1995 Mechanism of inhibition of eosinophil activation by transforming growth factor-beta. Inhibition of Lyn, MAP, Jak2 kinases and STAT1 nuclear factor.Journal of Immunology.  155:4454-4458. 1995
1995 Potentiation of B-cell antigen receptor-mediated signal transduction by the heterologous src family protein tyrosine kinase, src.Annals of the New York Academy of Sciences.  766:214-215. 1995
1995 A role in B cell activation for CD22 and the protein tyrosine phosphatase SHP.Science.  269:242-244. 1995
1995 The intracellular signal transduction mechanism of interleukin 5 in eosinophils: the involvement of lyn tyrosine kinase and the Ras-Raf-1-MEK-microtubule-associated protein kinase pathway.Journal of Experimental Medicine.  181:1827-1834. 1995
1994 Regulation of B-cell activation by CD45: a question of mechanism.Immunology Today.  15:399-406. 1994
1994 Multiple components of the B cell antigen receptor complex associate with the protein tyrosine phosphatase, CD45.Journal of Biological Chemistry.  269:17238-17244. 1994
1993 Administration of anti-CD45 mAb specific for a B cell-restricted epitope abrogates the B cell response to a T-dependent antigen in vivo.Journal of Immunology.  151:5936-5947. 1993
1992 Regulation of basal tyrosine phosphorylation of the B cell antigen receptor complex by the protein tyrosine phosphatase, CD45.Journal of Immunology.  149:3182-3190. 1992
1992 The MB-1/B29 heterodimer couples the B cell antigen receptor to multiple src family protein tyrosine kinases.Journal of Immunology.  149:1548-1555. 1992
1991 Regulation of B cell antigen receptor signal transduction and phosphorylation by CD45.Science.  252:1839-1842. 1991
1991 The B-cell antigen receptor complex.Immunology Today.  12:196-201. 1991
1991 Regulation of B cell antigen receptor slgnal transdiction and phosphorylation by CD45Science.  252. 1991
1990 Endogenously secreted IL-4 is required for mouse thymocytes to become cytotoxic. Human, but not mouse, IL-2 induces a functionally immature thymic subset to secrete IL-4 and become CTL.Immunology.  70:478-484. 1990
1990 Membrane IgM and IgD molecules fail to transduce Ca2+ mobilizing signals when expressed on differentiated B lineage cells.Journal of Immunology.  144:3272-3280. 1990
1990 Improved method for measuring intracellular Ca++ with fluo-3.Cytometry.  11:923-927. 1990
1989 Induction of c-fos and c-myc expression during B cell activation by IL-4 and immunoglobulin binding ligands.Journal of Immunology.  143:1032-1039. 1989
1989 Production of multiple lymphokines by the A20.1 B cell lymphoma after cross-linking of membrane Ig by immobilized anti-Ig.Journal of Immunology.  143:881-889. 1989
1988 B cell stimulatory factor 1 induces lobster agglutinin 1-separated mouse thymocytes to express cytotoxic T lymphocyte activity.Journal of Immunology.  141:145-150. 1988
1988 Biochemical characterization of proteins that co-purify with class II antigens of the murine MHC.Journal of Immunology.  140:1930-1938. 1988
1987 Ia binding ligands and cAMP stimulate nuclear translocation of PKC in B lymphocytes.Nature.  327:629-632. 1987
1987 Transmembrane signals and intracellular "second messengers" in the regulation of quiescent B-lymphocyte activation.Immunological Reviews.  95:37-57. 1987
1987 Coupling of B cell surface Ig, Ia and BSF1 receptors to intracellular "second messengers".Advances in Experimental Medicine and Biology.  213:195-205. 1987
1986 BSF1 induces membrane protein phosphorylation but not phosphoinositide metabolism, Ca2+ mobilization, protein kinase C translocation, or membrane depolarization in resting murine B lymphocytes.Journal of Immunology.  137:3664-3670. 1986
1986 Modulation of cyclic AMP-dependent protein kinase isozyme expression associated with activation of a macrophage cell line.Journal of Immunology.  136:270-277. 1986
1984 Inhibition of macrophage-mediated tumor cell destruction by oxidized lipoproteins.JNCI: Journal of the National Cancer Institute.  73:469-474. 1984
1984 Differential expression of cAMP dependent protein kinases in operationally defined populations of macrophagesFederation proceedings.  43. 1984

Book

Year Title Altmetric
1999 Signal transduction and the coordination of B lymphocyte development and function II. Translation of BCR signals to specific physiologic outcomes: Preface.  Ed. 245 II.  1999
1999 Signal transduction and the coordination of B lymphocyte development and function I: Preface.  Ed. 245 I.  1999

Chapter

Year Title Altmetric
2010 Signal transduction via the b cell antigen receptor. a crucial regulator of b cell biology.  2689-2698. 2010
2003 Signal Transduction via the B-Cell Antigen Receptor: A Crucial Regulator of B-Cell Biology.  555-564. 2003

Teaching Activities

  • GBS740A - Intro to Immunology Part 1 (Spring Term 2019) 2019
  • GBS740B - Intro to Immunology Part 2 (Spring Term 2019) 2019
  • GBSC742 - Student Theme Meeting Course (Spring Term 2019) 2019
  • MIC150 - Current Topics In Immunology (Spring Term 2019) 2019
  • MIC275 - Introductory Immunology (Spring Term 2019) 2019
  • MIC498 - Honors Research in Immunology (Spring Term 2019) 2019
  • GBSC742 - Student Theme Meeting Course (Fall Term 2018) 2018
  • MIC250 - Seminars in Immunology (Fall Term 2018) 2018
  • STP2043 - SURVIVAL SKILLS FOR PHYSICIAN SCIENTISTS (Fall Term 2018) 2018
  • MSTP794 - Translational Research Seminar (Summer Term 2018) 2018
  • GBS740A - Intro to Immunology Part 1 (Spring Term 2018) 2018
  • GBS740B - Intro to Immunology Part 2 (Spring Term 2018) 2018
  • GBSC722 - Special Topics (Spring Term 2018) 2018
  • MIC450 - Current Topics in Immunology (Spring Term 2018) 2018
  • MSTP794 - Translational Research Seminar (Spring Term 2018) 2018
  • GBS740A - INTRODUCTION TO IMMUNOLOGY A (Spring Term 2018) 2018
  • GBSC722 - Special Topics (Fall Term 2017) 2017
  • MSTP794 - Translational Research Seminar (Fall Term 2017) 2017
  • STP2043 - SURVIVAL SKILLS FOR PHYSICIAN SCIENTISTS (Fall Term 2017) 2017
  • MSTP794 - Translational Research Seminar (Summer Term 2017) 2017
  • GBS740A - Intro to Immunology Part 1 (Spring Term 2017) 2017
  • GBS740B - Intro to Immunology Part 2 (Spring Term 2017) 2017
  • GBSC701 - Seminars (Spring Term 2017) 2017
  • MSTP794 - Translational Research Seminar (Spring Term 2017) 2017
  • GBS740B - INTRODUCTION TO IMMUNOLOGY B (Spring Term 2017) 2017
  • GBS740A - INTRODUCTION TO IMMUNOLOGY A (Spring Term 2017) 2017
  • MIC710 - Dev Comm Skills for Bio (Fall Term 2016) 2016
  • MIC799 - Dissert Res Molecular Cell Bio (Fall Term 2016) 2016
  • MSTP794 - Translational Research Seminar (Fall Term 2016) 2016
  • STP2043 - SURVIVAL SKILLS FOR PHYSICIAN SCIENTISTS (Fall Term 2016) 2016
  • MSTP794 - Translational Research Seminar (Summer Term 2016) 2016
  • GBS740A - Intro to Immunology Part 1 (Spring Term 2016) 2016
  • GBS740B - Intro to Immunology Part 2 (Spring Term 2016) 2016
  • MIC710 - Dev Comm Skills for Bio (Spring Term 2016) 2016
  • MSTP794 - Translational Research Seminar (Spring Term 2016) 2016
  • STP2043 - SURVIVAL SKILLS FOR PHYSICIAN SCIENTISTS (Fall Term 2015) 2015
  • MSTP794 - Translational Research Seminar (Summer Term 2015) 2015
  • 32-241 - MICROBIOLOGY RESEARCH (Fall Term 2015) 2015
  • MSTP794 - Translational Research Seminar (Spring Term 2015) 2015
  • STP2043 - SURVIVAL SKILLS FOR PHYSICIAN SCIENTISTS (Fall Term 2014) 2014
  • STP2043 - SURVIVAL SKILLS FOR PHYSICIAN SCIENTISTS (Fall Term 2013) 2013
  • STP2043 - SURVIVAL SKILLS FOR PHYSICIAN SCIENTISTS (Fall Term 2013) 2013
  • 32-241 - MICROBIOLOGY RESEARCH (Spring Term 2013) 2013
  • STP2043 - SURVIVAL SKILLS FOR PHYSICIAN SCIENTISTS (Fall Term 2012) 2012
  • OBHS111 - Fundamentals of Dent and Opt I (Fall Term 2011) 2011
  • STP2043 - SURVIVAL SKILLS FOR PHYSICIAN SCIENTISTS (Fall Term 2011) 2011
  • STP2043 - SURVIVAL SKILLS FOR PHYSICIAN SCIENTISTS (Fall Term 2011) 2011
  • OBHS111 - Fundamentals of Dent and Opt I (Fall Term 2010) 2010
  • STP2043 - SURVIVAL SKILLS FOR PHYSICIAN SCIENTISTS (Fall Term 2010) 2010
  • MIC700 - Adv Course in Autoimmunity (Spring Term 2010) 2010
  • OBHS111 - Fundamentals of Dent and Opt I (Fall Term 2009) 2009
  • STP2043 - SURVIVAL SKILLS FOR PHYSICIAN SCIENTIST (Fall Term 2009) 2009
  • STP2043 - SURVIVAL SKILLS FOR PHYSICIAN SCIENTIST (Fall Term 2008) 2008
  • 01-530R - MICROBIOLOGY REMEDIATION (Fall Term 2008) 2008
  • 01-530 - MICROBIOLOGY/IMMUNOLOGY (Fall Term 2007) 2007
  • 01-530 - MICROBIOLOGY/IMMUNOLOGY (Fall Term 2007) 2007
  • Education And Training

  • Doctor of Philosophy in Microbiology, Ohio State University System : Columbus
  • Full Name

  • Louis Justement
  • Blazerid

  • lbjust