Positions

Selected Publications

Academic Article

Year Title Altmetric
2008 Dawn of the era of biologics in the treatment of the rheumatic diseases.Arthritis and Rheumatism.  58:S75-S78. 2008
2005 Cleavage of p53-vimentin complex enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis of rheumatoid arthritis synovial fibroblasts.American Journal of Pathology.  167:705-719. 2005
2004 Presentation of the 2004 Founders' Medal to J. Claude Bennett, MD.American Journal of the Medical Sciences.  328:251-253. 2004
2003 Fc gamma Rs modulate cytotoxicity of anti-Fas antibodies: implications for agonistic antibody-based therapeutics.Journal of Immunology.  171:562-568. 2003
2003 TRAIL-R2 (DR5) mediates apoptosis of synovial fibroblasts in rheumatoid arthritis.Journal of Immunology.  171:1061-1069. 2003
2002 Folic acid and folinic acid supplementation during low-dose methotrexate therapy for rheumatoid arthritis: comment on the article by van Ede et al.Arthritis and Rheumatism.  46:1413-1414. 2002
2001 Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity.Nature Medicine.  7:954-960. 2001
2001 Prospects for autoimmune disease: Research advances in rheumatoid arthritis.Journal of the American Medical Association.  285:648-650. 2001
1998 T cell receptor peptide vaccination in rheumatoid arthritis: a placebo-controlled trial using a combination of Vbeta3, Vbeta14, and Vbeta17 peptides.Arthritis and Rheumatism.  41:1919-1929. 1998
1998 In situ hybridization analysis of immunoglobulin heavy chain variable gene expression with family specific oligonucleotide probes.Journal of Immunological Methods.  218:31-52. 1998
1998 The effect of methotrexate and 7-hydroxymethotrexate on rat adjuvant arthritis and on urinary aminoimidazole carboxamide excretionArthritis and Rheumatism.  41:1407-1410. 1998
1998 Enhanced expression of immunoglobulin kappa light chains with unusually long CDR3 regions in patients with rheumatoid arthritis.Journal of Rheumatology.  25:1067-1071. 1998
1998 Clonally-related immunoglobulin VH domains and nonrandom use of DH gene segments in rheumatoid arthritis synovium.Molecular Medicine.  4:240-257. 1998
1998 Dendritic cells from Peyer's patch and spleen induce different T helper cell responses.Journal of Interferon and Cytokine Research.  18:103-115. 1998
1998 Nondepleting humanized anti-CD4 monoclonal antibody in patients with refractory rheumatoid arthritis.Journal of Rheumatology.  25:221-228. 1998
1998 Rheumatoid arthritis: anticytokine therapies on the horizon.Annals of Internal Medicine.  128:231-233. 1998
1997 Vaccination against rheumatoid arthritis: concepts and progress.Clinical immunotherapeutics.  8:87-95. 1997
1997 Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein.New England Journal of Medicine.  337:141-147. 1997
1997 Biologic agents for treating rheumatoid arthritis. Concepts and progress.Arthritis and Rheumatism.  40:397-409. 1997
1996 In situ hybridization and QC-RT-PCR analysis of arthroscopic biopsies of early rheumatoid arthritis synovial tissueFederation proceedings.  10. 1996
1996 Recombinant soluble tumor necrosis factor receptor (p80) fusion protein: toxicity and dose finding trial in refractory rheumatoid arthritis.Journal of Rheumatology.  23:1849-1855. 1996
1996 Suppression of in vitro IgM rheumatoid factor production by diphtheria toxin interleukin 2 recombinant fusion protein (DAB 486IL-2) in patients with refractory rheumatoid arthritis.Journal of Rheumatology.  23:1845-1848. 1996
1996 V beta 17 T cell receptor peptide vaccination in rheumatoid arthritis: results of phase I dose escalation study.Journal of Rheumatology.  23:1353-1362. 1996
1996 Editorial overview: Rheumatoid arthritisCurrent Opinion in Rheumatology.  8:201-202. 1996
1996 Dendritic cells from different tissues induce production of different T cell cytokine profiles.Journal of Leukocyte Biology.  59:494-498. 1996
1996 Quantitative analysis of immunoglobulin Vκ CDR3 lengths in rheumatoid arthritis: Evidence of antigenic selection or dysregulation of gene rearrangementJournal of Investigative Medicine.  44. 1996
1995 Double-blind, placebo-controlled multicenter trial using chimeric monoclonal anti-CD4 antibody, cM-T412, in rheumatoid arthritis patients receiving concomitant methotrexate.Arthritis and Rheumatism.  38:1581-1588. 1995
1995 Analysis of immunoglobulin gamma heavy chains from rheumatoid arthritis synovium. Evidence of antigen-driven selection.Annals of the New York Academy of Sciences.  764:450-452. 1995
1995 In situ hybridization analysis of immunoglobulin VH gene family expression in rheumatoid arthritis.Annals of the New York Academy of Sciences.  764:453-456. 1995
1995 Identifying nursing research priorities: general and neuroscience specific at an acute care hospital.Axone -Dartmouth then Halifax Nova Scotia-.  17:9-15. 1995
1995 Interleukin-2 diphtheria fusion protein (DAB486IL-2) in refractory rheumatoid arthritis. A double-blind, placebo-controlled trial with open-label extension.Arthritis and Rheumatism.  38:1177-1186. 1995
1995 Progressive joint destruction in a human immunodeficiency virus-infected patient with rheumatoid arthritis.Arthritis and Rheumatism.  38:1328-1332. 1995
1995 Somatic mutation and CDR3 lengths of immunoglobulin kappa light chains expressed in patients with rheumatoid arthritis and in normal individuals.Journal of Clinical Investigation.  96:831-841. 1995
1995 V beta 17 T-cell receptor peptide vaccine. Results of a phase I dose-finding study in patients with rheumatoid arthritis.Annals of the New York Academy of Sciences.  756:211-214. 1995
1995 Regeneration of T cells after chemotherapy.New England Journal of Medicine.  332:1650-1651. 1995
1995 Synovial Biopsy of the Knee Joint under Direct Visualization by Needle Arthroscopy.JCR: Journal of Clinical Rheumatology.  1:103-109. 1995
1995 Characterization of human Fas gene. Exon/intron organization and promoter region.Journal of Immunology.  154:1239-1245. 1995
1995 Dendritic cells regulate development of alloantigenic and mitogenic TH1 versus TH2 responses.Advances in Experimental Medicine and Biology.  378:347-349. 1995
1995 Immunoglobulin gene expression in rheumatoid arthritis.Agents and actions. Supplements.  47:23-35. 1995
1995 Molecular characterization of monoclonal IgM derived from human B cell lines expressing the 4C9 rheumatoid factor associated idiotype.Autoimmunity.  20:171-183. 1995
1995 Rheumatoid arthritis: Editorial overviewCurrent Opinion in Rheumatology.  7:199-200. 1995
1994 Supplementation with folic acid during methotrexate therapy for rheumatoid arthritis. A double-blind, placebo-controlled trial.Annals of Internal Medicine.  121:833-841. 1994
1994 Overexpression of zinc-finger transcription factor Z-225/Egr-1 in synoviocytes from rheumatoid arthritis patients.Journal of Immunology.  152:5940-5948. 1994
1994 The future of biologics in the treatment of rheumatoid arthritis.Seminars in Arthritis and Rheumatism.  23:50-58. 1994
1994 Treatment of refractory rheumatoid arthritis with a chimeric anti-CD4 monoclonal antibody. Long-term followup of CD4+ T cell counts.Arthritis and Rheumatism.  37:834-838. 1994
1994 Human rheumatoid factors with restrictive specificity for rabbit immunoglobulin G: auto- and multi-reactivity, diverse VH gene segment usage and preferential usage of V lambda IIIb.Journal of Experimental Medicine.  179:1445-1456. 1994
1994 HLA in ankylosing spondylitis: is HLA-B27 the only MHC gene involved in disease pathogenesis?Seminars in Arthritis and Rheumatism.  23:295-309. 1994
1994 Occurrence of deficient galactosylation of serum IgG prior to the onset of rheumatoid arthritisRheumatology International.  13:217-220. 1994
1994 Leucovorin versus folic acid in the treatment of methotrexate toxicity: comment on the article by Shiroky et al.Arthritis and Rheumatism.  37:444-445. 1994
1994 Survival impact of autoantibodies in systemic lupus erythematosus.Journal of Rheumatology.  21:224-228. 1994
1994 Erratum: Overexpression of zinc-finger transcription factor Z-225/Egr-1 in synoviocytes from rheumatoid arthritis patients (Blood (June 15, 1994) 152:12 (5940))Journal of Immunology.  153:5347. 1994
1994 Evidence of antigen receptor-influenced oligoclonal B lymphocyte expansion in the synovium of a patient with longstanding rheumatoid arthritis.Journal of Clinical Investigation.  93:361-370. 1994
1994 Expression of rheumatoid factor idiotypes 17.109, 6B6.6 and 4C9 in the sera of Pima Indians.Autoimmunity.  18:251-258. 1994
1994 T cell influence on superantigen-induced arthritis in MRL-lpr/lpr mice.Arthritis and Rheumatism.  37:113-124. 1994
1993 Effects of nonsteroidal antiinflammatory drugs on bone loss in chronic inflammatory disease.Annals of the New York Academy of Sciences.  696:292-302. 1993
1993 Anticardiolipin antibodies in systemic lupus erythematosus: clinical correlates, HLA associations, and impact on survival.Journal of Rheumatology.  20:1684-1693. 1993
1993 Analysis of immunoglobulin gamma heavy chain expression in synovial tissue of a patient with rheumatoid arthritis.Arthritis and Rheumatism.  36:631-641. 1993
1993 Host factors in the pathogenesis of arthritis triggered by infectious organisms. Overview.Rheumatic Disease Clinics of North America.  19:279-292. 1993
1993 Folate supplementation and methotrexate.Annals of the Rheumatic Diseases.  52:315-316. 1993
1993 Increased spontaneous secretion of rheumatoid factor by intestinal lamina propria mononuclear cells from Crohn's disease but not ulcerative colitis patients.Clinical and Experimental Immunology.  92:152-157. 1993
1993 Antifolates in rheumatoid arthritis: a hypothetical mechanism of action.Clinical and Experimental Rheumatology.  11 Suppl 8:S101-S105. 1993
1993 Experience with a chimeric monoclonal anti-CD4 antibody in the treatment of refractory rheumatoid arthritis.Clinical and Experimental Rheumatology.  11 Suppl 8:S153-S159. 1993
1993 Molecular and cellular mechanisms of joint destruction in rheumatoid arthritis: two cellular mechanisms explain joint destruction?Annals of the Rheumatic Diseases.  52 Suppl 1:S39-S47. 1993
1993 Use of a chimeric monoclonal anti-CD4 antibody in patients with refractory rheumatoid arthritis.Arthritis and Rheumatism.  36:307-318. 1993
1993 Do nonimmunologically mediated pathways play a role in the pathogenesis of rheumatoid arthritis?Rheumatic Disease Clinics of North America.  19:107-122. 1993
1993 The use of monozygotic and dizygotic twins to estimate the effects of inheritance on the levels of immunoglobulin isotypes and antibodies to phosphocholine.Clinical immunology and immunopathology.  66:176-180. 1993
1993 Divergent T-cell cytokine profiles induced by dendritic cells from different tissues.Advances in Experimental Medicine and Biology.  329:47-52. 1993
1993 New approaches to the therapy of autoimmune diseases: rheumatoid arthritis as a paradigm.American Journal of the Medical Sciences.  305:40-51. 1993
1993 Nonperipheral accelerated nodulosis in a methotrexate-treated rheumatoid arthritis patient.Arthritis and Rheumatism.  36:132-133. 1993
1992 Digital subtraction radiography for the assessment of bone changes in rheumatoid arthritis.Journal of Rheumatology.  19:1697-1703. 1992
1992 Efficacy and safety of 10-deazaaminopterin in the treatment of rheumatoid arthritis. A one-year continuation, double-blind study.Arthritis and Rheumatism.  35:1318-1321. 1992
1992 A rheumatoid factor from a normal individual encoded by VH2 and V kappa II gene segments.Arthritis and Rheumatism.  35:900-904. 1992
1992 Infection as a cause of reactive arthritis, ankylosing spondylitis, and rheumatic fever.Current Opinion in Rheumatology.  4:534-542. 1992
1992 The immunoglobulin kappa light chain repertoire expressed in the synovium of a patient with rheumatoid arthritis.Arthritis and Rheumatism.  35:905-913. 1992
1992 Controlled trial of methotrexate versus 10-deazaaminopterin in the treatment of rheumatoid arthritis.Annals of the Rheumatic Diseases.  51:600-603. 1992
1992 Local immune responses in certain extra-articular manifestations of rheumatoid arthritis.Annals of the Rheumatic Diseases.  51:698-701. 1992
1992 Expressing our inner thoughts: how to organize and write a clinical research project grant application.Journal of Rheumatology -Supplement-.  33:16-19. 1992
1992 Abnormal galactosylation of serum IgG in patients with systemic lupus erythematosus and members of families with high frequency of autoimmune diseases.Rheumatology International.  12:191-194. 1992
1992 Long-term treatment of the MRL/lpr mouse with methotrexate and 10-deazaaminopterin.Agents and actions.  35:104-111. 1992
1992 Scanning electron microscopic evaluation of the arthritis in MRL/lpr mice.Rheumatology International.  12:115-120. 1992
1991 Apolipoprotein A-I decreases neutrophil degranulation and superoxide production.Journal of Lipid Research.  32:1911-1918. 1991
1991 Genetic studies of four highly homologous rheumatoid factor-associated Vk genes in rheumatoid arthritis patients and normal individuals.Molecular Immunology.  28:1073-1083. 1991
1991 In search of Mr. Wizard. Presidential Address to the American Society for Clinical Investigation, Seattle, Washington, 4 May 1991.Journal of Clinical Investigation.  88:1063-1066. 1991
1991 Cellular origins of human polymeric and monomeric IgA: enumeration of single cells secreting polymeric IgA1 and IgA2 in peripheral blood, bone marrow, spleen, gingiva and synovial tissue.Clinical and Experimental Immunology.  85:341-348. 1991
1991 Infection as a cause of arthritis.Current Opinion in Rheumatology.  3:639-649. 1991
1991 Rheumatology.Journal of the American Medical Association.  265:3169-3170. 1991
1991 The American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the hip.Arthritis and Rheumatism.  34:505-514. 1991
1991 Local IgA and IgM rheumatoid factor production in autoimmune MRL/lpr mice.Autoimmunity.  10:7-14. 1991
1991 ReplyArthritis and Rheumatism.  34:120-121. 1991
1990 The American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the hand.Arthritis and Rheumatism.  33:1601-1610. 1990
1990 Elucidating the pathogenesis of autoimmune disease: recent advances at the molecular level and relevance to oral mucosal disease.Journal of Oral Pathology and Medicine.  19:341-350. 1990
1990 Structural characterization of the second major cross-reactive idiotype group of human rheumatoid factors. Association with the VH4 gene family.Arthritis and Rheumatism.  33:1347-1360. 1990
1990 Suppression of rheumatoid factor production by methotrexate in patients with rheumatoid arthritis. Evidence for differential influences of therapy and clinical status on IgM and IgA rheumatoid factor expression.Arthritis and Rheumatism.  33:1156-1161. 1990
1990 Dissociation of expression of two rheumatoid factor cross-reactive kappa L chain idiotopes in rheumatoid arthritis.Journal of Immunology.  144:3468-3472. 1990
1990 Synergism of interleukin 7 with the thymocyte growth factors interleukin 2, interleukin 6, and tumor necrosis factor alpha in the induction of thymocyte proliferation.Cellular Immunology.  127:470-482. 1990
1990 Lupus-inducing drugs alter the structure of supercoiled circular DNA domains.Arthritis and Rheumatism.  33:366-374. 1990
1990 Osteoarthritis: definitions and criteria.Annals of the Rheumatic Diseases.  49:201. 1990
1990 Monoclonal antibody 6B6.6 defines a cross-reactive kappa light chain idiotope on human monoclonal and polyclonal rheumatoid factors.Arthritis and Rheumatism.  33:187-198. 1990
1990 Achieving consensus on an algorithm for the treatment of rheumatoid arthritis with MethotrexateArthritis and Rheumatism.  3:53-58. 1990
1990 Achieving consensus on an algorithm for the treatment of rheumatoid arthritis with methotrexateArthritis and Rheumatism.  3:53-57. 1990
1990 Correlation of serologic indicators of inflammation with effectiveness of nonsteroidal antiinflammatory drug therapy in rheumatoid arthritis.Arthritis and Rheumatism.  33:19-28. 1990
1990 Methotrexate therapy in rheumatoid arthritis patients diminishes lectin-induced mononuclear cell proliferation.Rheumatology International.  10:165-169. 1990
1990 Occurrence of a rheumatoid factor cross-reactive kappa light-chain idiotope in rheumatoid arthritis families.Rheumatology International.  10:211-215. 1990
1990 Rheumatoid factor and human diseaseClinical Immunology Newsletter.  10:137-141. 1990
1989 The replyAmerican Journal of Medicine.  86:634. 1989
1989 Molecular analysis of HLA-D region genes in seropositive rheumatoid arthritis.Tissue Antigens.  34:299-308. 1989
1989 Exquisite sensitivity of dendritic cells to ultraviolet radiation and temperature changes.Transplantation.  48:666-671. 1989
1989 Methotrexate-induced liver abnormalities in rheumatoid arthritis.Journal of Rheumatology.  16:1180-1183. 1989
1989 Secretion of antibodies to types I and II collagen by synovial tissue cells in patients with rheumatoid arthritis.Arthritis and Rheumatism.  32:1087-1092. 1989
1989 Viral arthritis in humans.Current Opinion in Rheumatology.  1:185-193. 1989
1989 Local production of IgA- and IgM-rheumatoid factors in adult periodontal disease.Journal of Clinical Immunology.  9:273-278. 1989
1989 Severe reversible interstitial pneumonitis induced by low dose methotrexate.Journal of Rheumatology.  16:1007-1008. 1989
1989 Immunopathology of rheumatoid arthritis.Current Opinion in Rheumatology.  1:8-14. 1989
1989 Interleukins and IgA synthesis. Human and murine interleukin 6 induce high rate IgA secretion in IgA-committed B cells.Journal of Experimental Medicine.  169:2133-2148. 1989
1989 Valvular heart disease in systemic lupus erythematosus.New England Journal of Medicine.  320:739-741. 1989
1989 Analysis of human IgG and IgA subclass antibody-secreting cells from localized chronic inflammatory tissue.Journal of Immunology.  142:1150-1158. 1989
1989 Enhancement of IL-2-induced T cell proliferation by a novel factor(s) present in murine spleen dendritic cell-T cell culture supernatants.Journal of Immunology.  142:1183-1194. 1989
1989 Comment on the article by Tomana et al.Arthritis and Rheumatism.  32:235-236. 1989
1989 Radiologic assessment as an outcome measure in rheumatoid arthritis.Arthritis and Rheumatism.  32:221-229. 1989
1989 AS and a 9.2 kb Pvu II class I HLA DNA restriction fragment.Journal of Rheumatology.  16:141-142. 1989
1989 Identification of peptide hormones of the amphipathic helix class using the helical hydrophobic moment algorithm.Proteins.  6:61-69. 1989
1989 Mucosal homeostasis: role of interleukins, isotype-specific factors and contrasuppression in the IgA response.Immunological communications.  18:77-89. 1989
1988 Molecular genetic studies of rheumatoid arthritis.American Journal of Medicine.  85:23-25. 1988
1988 Restriction fragment length polymorphism analysis in ankylosing spondylitis.American Journal of Medicine.  85:48-50. 1988
1988 Autoimmunity to collagen in adult periodontal disease.Journal of oral pathology.  17:456-459. 1988
1988 Clinically significant valvular heart disease in systemic lupus erythematosus.American Journal of Medicine.  85:645-650. 1988
1988 Ultrastructural study of Sjögren's syndrome-like disease in MRL/l mice.Journal of oral pathology.  17:460-465. 1988
1988 Recombinant murine IL-5 induces high rate IgA synthesis in cycling IgA-positive Peyer's patch B cells.Journal of Immunology.  141:2035-2042. 1988
1988 Occurrence of polymeric IgA1 rheumatoid factor in the acquired immune deficiency syndrome.Journal of Clinical Immunology.  8:390-396. 1988
1988 Incidence of three cross-reactive idiotypes on human rheumatoid factor paraproteins.Journal of Immunology.  140:3411-3418. 1988
1988 Re: Methotrexate in the treatment of arthritis and connective tissue disease.Cleveland Clinic Journal of Medicine.  55:279. 1988
1988 Features of renal vasculitis in autoimmune MRL lpr/lpr mice: phenotypes and functional properties of infiltrating cells.Clinical and Experimental Immunology.  72:91-97. 1988
1988 Abnormal glycosylation of serum IgG from patients with chronic inflammatory diseases.Arthritis and Rheumatism.  31:333-338. 1988
1988 Etiopathogenesis of rheumatoid arthritis-like disease in MRL/1 mice: II. Ultrastructural basis of joint destruction.Journal of Rheumatology.  15:10-16. 1988
1988 Occurrence of a mu-chain idiotope in two human monoclonal RF which also share a kappa-chain idiotope.Scandinavian Journal of Rheumatology -Supplement-.  75:102-108. 1988
1988 Rheumatoid factor diversity.In Vivo.  2:73-77. 1988
1988 The MRL-lpr/lpr mouse. A model for the study of rheumatoid arthritis.Scandinavian Journal of Rheumatology -Supplement-.  75:284-289. 1988
1987 Striking elevation of serum IgA, IgA-containing immune complexes, and IgA rheumatoid factor in clinically silent dermatitis herpetiformis.American Journal of Kidney Diseases.  10:378-384. 1987
1987 Analyses of HLA linkage in white families with multiple cases of seropositive rheumatoid arthritis.Arthritis and Rheumatism.  30:1115-1123. 1987
1987 Humoral sensitivity to native collagen types I-VI in the arthritis of MRL/l mice.Clinical immunology and immunopathology.  45:63-69. 1987
1987 A low molecular weight, heat-labile factor enhances neutrophil Fc receptor-mediated lysosomal enzyme release and phagocytosis.Arthritis and Rheumatism.  30:1006-1014. 1987
1987 Analysis of restriction fragment length polymorphisms in rheumatic diseases.Rheumatic Disease Clinics of North America.  13:353-367. 1987
1987 Association of a 9.2-kilobase Pvu II class I major histocompatibility complex restriction fragment length polymorphism with ankylosing spondylitis.Arthritis and Rheumatism.  30:894-900. 1987
1987 Specificity of monoclonal anti-Z-DNA antibodies from unimmunized MRL/Mp-lpr/lpr mice.Journal of Immunology.  139:743-748. 1987
1987 Streptococcal serotype carbohydrate represents a novel class of type 2 antigen which is T-independent.Journal of Immunology.  138:4387-4394. 1987
1987 Development of clinical criteria for osteoarthritis.Journal of Rheumatology.  14 Spec No:3-6. 1987
1987 Acute cryoglobulinemic renal failure after intravenous infusion of gamma globulin.American Journal of Medicine.  82:624-629. 1987
1987 Airways disease in rheumatoid arthritis patients. One element of a general exocrine dysfunction.Arthritis and Rheumatism.  30:249-256. 1987
1987 Lack of association between HLA-DR2 and clinical response to methotrexate in patients with rheumatoid arthritis.Arthritis and Rheumatism.  30:218-220. 1987
1987 Toxicity due to remission inducing drugs in RA.Journal of Rheumatology.  14:175-176. 1987
1987 Toxicity of methotrexate in rheumatoid arthritis.Journal of Rheumatology.  14:74-79. 1987
1987 Analysis of paraprotein transport into the saliva by using anti-idiotype antibodies.Journal of Immunology.  138:435-439. 1987
1987 Differential expression of IgA- and IgM-rheumatoid factors in human disease: evidence for independent regulation of rheumatoid factor isotype production.Advances in Experimental Medicine and Biology.  216B:1627-1639. 1987
1987 Enhanced in vitro IgM rheumatoid factor synthesis in seropositive rheumatoid arthritis families.Rheumatology International.  7:71-75. 1987
1987 Immunological studies of IgA nephropathy: familial and racial aspects.Advances in Experimental Medicine and Biology.  216B:1489-1498. 1987
1987 Review of the national arthritis advisory board symposium, “molecular biology: its potential for advancing rheumatology research”Arthritis and Rheumatism.  30:1191-1194. 1987
1986 Molecular forms of IgA rheumatoid factor in serum and synovial fluid of patients with rheumatoid arthritis.Arthritis and Rheumatism.  29:1194-1202. 1986
1986 VH gene expression is restricted in anti-IgG antibodies from MRL autoimmune mice.Journal of Experimental Medicine.  164:1284-1300. 1986
1986 Interleukin 1-like factor produced by a hybrid of an adherent mouse spleen cell and a thymoma cell.Immunology Letters.  13:143-149. 1986
1986 Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association.Arthritis and Rheumatism.  29:1039-1049. 1986
1986 Induction of neutrophil enzyme release by rheumatoid factors: evidence for differences based on molecular characteristics.Clinical immunology and immunopathology.  40:347-355. 1986
1986 Circulating immune complexes and immunoglobulin A rheumatoid factor in patients with mesangial immunoglobulin A nephropathies.Journal of Clinical Investigation.  77:1931-1938. 1986
1986 Rheumatoid arthritis associated with expanded populations of granular lymphocytes.Annals of Internal Medicine.  104:314-323. 1986
1986 DR2 positivity and response to methotrexate in rheumatoid arthritis.Arthritis and Rheumatism.  29:151. 1986
1986 HLA antigens and gold toxicity in American blacks with rheumatoid arthritis.Rheumatology International.  6:13-17. 1986
1985 Relationship between in vitro IgM rheumatoid factor (RF) synthesis and the response to gold therapy in rheumatoid arthritis (RA) patients.Arthritis and Rheumatism.  28:1439-1440. 1985
1985 IgA rheumatoid factor synthesis by dissociated synovial cells. Characterization and relationship to IgM rheumatoid factor synthesis.Arthritis and Rheumatism.  28:1219-1227. 1985
1985 Solid-phase radioimmunoassay for human neutrophil elastase: a sensitive method for determining secreted and cell-associated enzyme.Analytical Biochemistry.  150:18-25. 1985
1985 The carpometarcarpal ratio: a useful method for assessing disease progression in rheumatoid arthritis.Journal of Rheumatology.  12:846-848. 1985
1985 Production of immunoglobulin and rheumatoid factor by lymphoid cells in rheumatoid pericardium.Arthritis and Rheumatism.  28:1071-1074. 1985
1985 Interaction of DNA with connective tissue matrix proteins reveals preferential binding to type V collagen.Journal of Immunology.  135:1097-1100. 1985
1985 Immunoglobulin subclass distribution of synovial plasma cells in rheumatoid arthritis determined by use of monoclonal anti-subclass antibodies.Clinical immunology and immunopathology.  35:346-351. 1985
1985 Etiopathogenesis of the rheumatoid arthritis-like disease in MRL/l mice. I. The histomorphologic basis of joint destruction.Arthritis and Rheumatism.  28:529-536. 1985
1985 Activity of rheumatoid factors of different molecular sizes: comparison of autologous monomeric and polymeric monoclonal IgA rheumatoid factors.Journal of Immunology.  134:1469-1474. 1985
1985 In vitro IgM and IgM rheumatoid factor production and response to remittive agents in rheumatoid arthritis.Arthritis and Rheumatism.  28:356-357. 1985
1985 HLA-Bw35 and gold toxicity in rheumatoid arthritis.Arthritis and Rheumatism.  28:236-237. 1985
1985 Antiisotypic antibodies.Methods in Enzymology.  116:146-156. 1985
1985 IgA-IgG immune complexes and rheumatoid factor in IgA nephropathyFederation proceedings.  44. 1985
1984 Peyer's patch dendritic cells: isolation and functional comparison with murine spleen dendritic cells.Immunobiology.  168:380-390. 1984
1984 Penicillamine-induced myositis. Observations and unique features in two patients and review of the literature.American Journal of Medicine.  77:719-722. 1984
1984 Isotype-specificity of helper T cell clones: Fc alpha receptors regulate T and B cell collaboration for IgA responses.Journal of Immunology.  133:1087-1089. 1984
1984 Preferential induction of polyclonal IgA secretion by murine Peyer's patch dendritic cell-T cell mixtures.Journal of Experimental Medicine.  160:941-946. 1984
1984 Rheumatoid myositis. Clinical and histologic features and possible pathogenesis.Arthritis and Rheumatism.  27:737-743. 1984
1984 DR antigens and gold toxicity in white rheumatoid arthritis patients.Arthritis and Rheumatism.  27:601-605. 1984
1984 Isotype specificity of helper T cell clones. Peyer's patch Th cells preferentially collaborate with mature IgA B cells for IgA responses.Journal of Experimental Medicine.  159:798-811. 1984
1984 Effects of ultraviolet light and interleukin-1 on dendritic cell functionFederation proceedings.  43. 1984
1984 In vitro synthesis of IgM and IgM rheumatoid factor in seronegative arthritides.Rheumatology International.  4:49-53. 1984
1984 Mucosal immunoregulation: environmental lipopolysaccharide and GALT T lymphocytes regulate the IgA response.Microbiology and Immunology.  28:261-280. 1984
1984 Partial characterisation of the high and low molecular weight forms of P388D1-derived interleukin 1.Journal of Cellular Biochemistry.  26:65-73. 1984
1983 CREG antigens differentially influence expression of extraarticular manifestations in whites and blacks with rheumatoid arthritis.Seminars in Arthritis and Rheumatism.  13:169-173. 1983
1983 Seronegative rheumatoid arthritis and B7-CREG: disparate results.Arthritis and Rheumatism.  26:1412-1413. 1983
1983 Suppression of in vitro monoclonal human rheumatoid factor synthesis by antiidiotypic antibody. Target cells and molecular requirements.Journal of Clinical Investigation.  72:1410-1419. 1983
1983 DR antigen distribution in Blacks with rheumatoid arthritis.Journal of Rheumatology.  10:579-583. 1983
1983 IgA rheumatoid factor: evidence for independent expression at local sites of tissue inflammation.Annals of the New York Academy of Sciences.  409:258-272. 1983
1983 The IgA response: inductive aspects, regulatory cells, and effector functions.Annals of the New York Academy of Sciences.  409:48-71. 1983
1983 Accessory cells in murine Peyer's patch. I. Identification and enrichment of a functional dendritic cell.Journal of Experimental Medicine.  157:1646-1659. 1983
1983 Local synthesis of IgM and IgM rheumatoid factor in rheumatoid pleuritis.Journal of Rheumatology.  10:204-209. 1983
1983 Lymphoid cell responses to bacterial cell wall components: murine B-cell responses to a purified cell wall moiety of Actinomyces.Scandinavian Journal of Immunology.  17:313-322. 1983
1983 Serum IgA1 and IgA2 in normal adults and patients with systemic lupus erythematosus and hepatic disease.Clinical immunology and immunopathology.  26:390-397. 1983
1983 IDENTIFICATION OF A NONADHERENT ACCESSORY CELL IN MURINE PEYER'S PATCHESAnnals of the New York Academy of Sciences.  409:880-881. 1983
1983 MURINE PEYER'S PATCH T‐HELPER CELL CLONES THAT PREFERENTIALLY SUPPORT IgA RESPONSESAnnals of the New York Academy of Sciences.  409:829-830. 1983
1983 PEYER'S PATCH ACCESSORY CELLS BEAR I‐AAnnals of the New York Academy of Sciences.  409:819-821. 1983
1983 REGULATION OF IgA SUBCLASSES IN POKEWEED MITOGEN STIMULATED CULTURESAnnals of the New York Academy of Sciences.  409:797-798. 1983
1982 In vitro regulation of IgA subclass synthesis. I. Discordance between plasma cell production and antibody secretion.Journal of Experimental Medicine.  156:1615-1621. 1982
1982 Murine Peyer's patch T cell clones. Characterization of antigen-specific helper T cells for immunoglobulin A responses.Journal of Experimental Medicine.  156:1115-1130. 1982
1982 Seronegative rheumatoid arthritis. A distinct immunogenetic disease?Arthritis and Rheumatism.  25:502-507. 1982
1982 Buffer electrofocusing of Interleukin I.Bioscience Reports.  2:241-246. 1982
1982 Differential patterns of in vitro IgM rheumatoid factor synthesis in seronegative and seropositive rheumatoid arthritis.Arthritis and Rheumatism.  25:150-155. 1982
1982 A quantitative assay for IgA rheumatoid factor.Journal of Immunological Methods.  50:89-98. 1982
1982 An enzymatic method for preparation of dissociated murine Peyer's patch cells enriched for macrophages.Journal of Immunological Methods.  48:33-44. 1982
1981 Suppressor T cells prevent in vitro expression of IgM rheumatoid factor in some health adults.Proceedings of the Society for Experimental Biology and Medicine.  168:344-349. 1981
1981 Lymphoid cell responses to bacterial cell wall components: polyclonal and immune responses of murine B cells to Streptococcus mutans carbohydrate antigens.Journal of Immunology.  127:2106-2112. 1981
1981 Interleukin 1: production by P388D1 cells attached to microcarrier beads.Journal of Immunological Methods.  46:197-204. 1981
1980 Production of predominantly polymeric IgA by human peripheral blood lymphocytes stimulated in vitro with mitogens.Journal of Experimental Medicine.  152:1424-1429. 1980
1980 Enhanced in vitro synthesis of IgM rheumatoid factor in rheumatoid arthritis.Arthritis and Rheumatism.  23:985-992. 1980
1980 In vitro synthesis of IgM rheumatoid factor by lymphocytes from healthy adults.Journal of Immunology.  125:934-939. 1980
1980 A sensitive radioimmunoassay for quantitation of IgM rheumatoid factor.Arthritis and Rheumatism.  23:302-308. 1980

Education And Training

  • Doctor of Medicine in Immunology, Harvard University
  • Full Name

  • William Koopman
  • Blazerid

  • koopman