Positions

Selected Publications

Academic Article

Year Title Altmetric
2008 Dawn of the era of biologics in the treatment of the rheumatic diseasesArthritis and Rheumatism.  58. 2008
2005 Cleavage of p53-vimentin complex enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis of rheumatoid arthritis synovial fibroblastsAmerican Journal of Pathology.  167:705-719. 2005
2004 Presentation of the 2004 Founders' Medal to J. Claude Bennett, MD.American Journal of the Medical Sciences.  328:251-253. 2004
2003 FcγRs modulate cytotoxicity of anti-Fas antibodies: Implications for agonistic antibody-based therapeuticsJournal of Immunology.  171:562-568. 2003
2003 TRAIL-R2 (DR5) mediates apoptosis of synovial fibroblasts in rheumatoid arthritisJournal of Immunology.  171:1061-1069. 2003
2002 Folic acid and folinic acid supplementation during low-dose methotrexate therapy for rheumatoid arthritis: Comment on the article by van Ede et al [6]Arthritis and Rheumatism.  46:1413-1414. 2002
2001 Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicityNature Medicine.  7:954-960. 2001
2001 Prospects for autoimmune disease: Research advances in rheumatoid arthritisJournal of the American Medical Association.  285:648-650. 2001
1998 T cell receptor peptide vaccination in rheumatoid arthritis: A placebo- controlled trial using a combination of V(β)3, V(β)14, and V(β)17 peptidesArthritis and Rheumatism.  41:1919-1929. 1998
1998 In situ hybridization analysis of immunoglobulin heavy chain variable gene expression with family specific oligonucleotide probesJournal of Immunological Methods.  218:31-52. 1998
1998 The effect of methotrexate and 7-hydroxymethotrexate on rat adjuvant arthritis and on urinary aminoimidazole carboxamide excretionArthritis and Rheumatism.  41:1407-1410. 1998
1998 Clonally-related immunoglobulin V(H) domains and nonrandom use of D(H) gene segments in rheumatoid arthritis synoviumMolecular Medicine.  4:240-257. 1998
1998 Enhanced expression of immunoglobulin κ light chains with unusually long CDR3 regions in patients with rheumatoid arthritisJournal of Rheumatology.  25:1067-1071. 1998
1998 Nondepleting humanized anti-CD4 monoclonal antibody in patients with refractory rheumatoid arthritisJournal of Rheumatology.  25:221-228. 1998
1998 Rheumatoid arthritis: Anticytokine therapies on the horizonAnnals of Internal Medicine.  128:231-233. 1998
1998 Dendritic cells from Peyer's patch and spleen induce different T helper cell responsesJournal of Interferon and Cytokine Research.  18:103-115. 1998
1997 Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion proteinNew England Journal of Medicine.  337:141-147. 1997
1997 Biologic agents for treating rheumatoid arthritis: Concepts and progressArthritis and Rheumatism.  40:397-409. 1997
1997 Vaccination against rheumatoid arthritis. Concepts and progressClinical immunotherapeutics.  8:87-95. 1997
1996 In situ hybridization and QC-RT-PCR analysis of arthroscopic biopsies of early rheumatoid arthritis synovial tissueFederation proceedings.  10. 1996
1996 Recombinant soluble tumor necrosis factor receptor (p80) fusion protein: Toxicity and dose finding trial in refractory rheumatoid arthritisJournal of Rheumatology.  23:1849-1855. 1996
1996 Suppression of in vitro IgM rheumatoid factor production by diphtheria toxin interleukin 2 recombinant fusion protein (DAB 486IL-2) in patients with refractory rheumatoid arthritisJournal of Rheumatology.  23:1845-1848. 1996
1996 Vβ17 T cell receptor peptide vaccination in rheumatoid arthritis: Results of phase I dose escalation studyJournal of Rheumatology.  23:1353-1362. 1996
1996 Editorial overview: Rheumatoid arthritisCurrent Opinion in Rheumatology.  8:201-202. 1996
1996 Dendritic cells from different tissues induce production of different T cell cytokine profilesJournal of Leukocyte Biology.  59:494-498. 1996
1996 Quantitative analysis of immunoglobulin Vκ CDR3 lengths in rheumatoid arthritis: Evidence of antigenic selection or dysregulation of gene rearrangementJournal of Investigative Medicine.  44. 1996
1995 Identifying nursing research priorities: general and neuroscience specific at an acute care hospital.Axone -Dartmouth then Halifax Nova Scotia-.  17:9-15. 1995
1995 Regeneration of t cells after chemotherapyNew England Journal of Medicine.  332:1650-1652. 1995
1995 Analysis of Immunoglobulin Gamma Heavy Chains from Rheumatoid Arthritis Synovium Evidence of Antigen‐Driven SelectionAnnals of the New York Academy of Sciences.  764:450-460. 1995
1995 Characterization of human Fas gene: Exon/intron organization and promoter regionJournal of Immunology.  154:1239-1245. 1995
1995 Dendritic cells regulate development of alloantigenic and mitogenic T(H)1 versus T(H)2 responsesAdvances in Experimental Medicine and Biology.  378:347-349. 1995
1995 Double‐blind, placebo‐controlled multicenter trial using chimeric monoclonal anti‐cd4 antibody, cm‐t412, in rheumatoid arthritis patients receiving concomitant methotrexateArthritis and Rheumatism.  38:1581-1588. 1995
1995 Immunoglobulin gene expression in rheumatoid arthritisAgents and Actions Supplements.  47:23-35. 1995
1995 In Situ Hybridization Analysis of Immunoglobulin VH Gene Family Expression in Rheumatoid ArthritisAnnals of the New York Academy of Sciences.  764:453-456. 1995
1995 Interleukin‐2 diphtheria fusion protein (dab486il‐2) in refractory rheumatoid arthritis a double‐blind, placebo‐controlled trial with open‐label extensionArthritis and Rheumatism.  38:1177-1186. 1995
1995 Molecular characterization of monoclonal igm derived from human b cell lines expressing the 4c9 rheumatoid factor associated idiotypeAutoimmunity.  20:171-183. 1995
1995 Progressive joint destruction in a human immunodeficiency virus‐infected patient with rheumatoid arthritisArthritis and Rheumatism.  38:1328-1332. 1995
1995 Rheumatoid arthritis: Editorial overviewCurrent Opinion in Rheumatology.  7:199-200. 1995
1995 Somatic mutation and CDR3 lengths of immunoglobulin κ light chains expressed in patients with rheumatoid arthritis and in normal individualsJournal of Clinical Investigation.  96:831-841. 1995
1995 Synovial biopsy of the knee joint under direct visualization by needle arthroscopyJCR: Journal of Clinical Rheumatology.  1:103-109. 1995
1995 Vβ17 T‐Cell Receptor Peptide Vaccine: Results of a Phase I Dose‐Finding Study in Patients with Rheumatoid ArthritisAnnals of the New York Academy of Sciences.  756:211-214. 1995
1994 Supplementation with folic acid during methotrexate therapy for rheumatoid arthritis: A double-blind, placebo-controlled trialAnnals of Internal Medicine.  121:833-841. 1994
1994 Overexpression of zinc-finger transcription factor Z-225/Egr-1 in synoviocytes from rheumatoid arthritis patientsJournal of Immunology.  152:5940-5948. 1994
1994 Human rheumatoid factors with restrictive specificity for rabbit immunoglobulin G: Auto- and multi-reactivity, diverse VH gene segment usage and preferential usage of VλIIlbJournal of Experimental Medicine.  179:1445-1456. 1994
1994 Occurrence of deficient galactosylation of serum IgG prior to the onset of rheumatoid arthritisRheumatology International.  13:217-220. 1994
1994 Erratum: Overexpression of zinc-finger transcription factor Z-225/Egr-1 in synoviocytes from rheumatoid arthritis patients (Blood (June 15, 1994) 152:12 (5940))Journal of Immunology.  153:5347. 1994
1994 Evidence of antigen receptor-influenced oligoclonal B lymphocyte expansion in the synovium of a patient with longstanding rheumatoid arthritisJournal of Clinical Investigation.  93:361-370. 1994
1994 Expression of rheumatoid factor idiotypes 17.109, 6b6.6 and 4c9 in the sera of pima indiansAutoimmunity.  18:251-258. 1994
1994 HLA in ankylosing spondylitis: Is HLA-B27 the only MHC gene involved in disease pathogenesis?Seminars in Arthritis and Rheumatism.  23:295-309. 1994
1994 Leucovorin Versus Folic Acid in the Treatment of Methotrexate Toxicity: Comment on the Article by Shiroky et a1Arthritis and Rheumatism.  37:444-444. 1994
1994 Survival impact of autoantibodies in systemic lupus erythematosusJournal of Rheumatology.  21:224-228. 1994
1994 T Cell Influence on Superantigen‐Induced Arthritis in MRL‐lpr/lpr MiceArthritis and Rheumatism.  37:113-124. 1994
1994 The future of biologies in the treatment of rheumatoid arthritisSeminars in Arthritis and Rheumatism.  23:50-58. 1994
1994 Treatment of refractory rheumatoid arthritis with a chimeric ANTI‐CD4 monoclonal antibodyArthritis and Rheumatism.  37:834-838. 1994
1993 Analysis of immunoglobulin gamma heavy chain expression in synovial tissue of a patient with rheumatoid arthritisArthritis and Rheumatism.  36:631-641. 1993
1993 Anticardiolipin antibodies in systemic lupus erythematosus: Clinical correlates, HLA associations, and impact on survivalJournal of Rheumatology.  20:1684-1693. 1993
1993 Antifolates in rheumatoid arthritis: A hypothetical mechanism of actionClinical and Experimental Rheumatology.  11. 1993
1993 Divergent T-cell cytokine profiles induced by dendritic cells from different tissuesAdvances in Experimental Medicine and Biology.  329:47-53. 1993
1993 Do nonimmunologically mediated pathways play a role in the pathogenesis of rheumatoid arthritis?Rheumatic Disease Clinics of North America.  19:107-122. 1993
1993 Effects of Nonsteroidal Antiinflammatory Drugs on Bone Loss in Chronic Inflammatory DiseaseAnnals of the New York Academy of Sciences.  696:292-302. 1993
1993 Experience with a chimeric monoclonal anti-CD4 antibody in the treatment of refractory rheumatoid arthritisClinical and Experimental Rheumatology.  11. 1993
1993 Folate supplementation and methotrexate [3]Annals of the Rheumatic Diseases.  52:315-316. 1993
1993 Host factors in the pathogenesis of arthritis triggered by infectious organismsRheumatic Disease Clinics of North America.  19:279-292. 1993
1993 Increased spontaneous secretion of rheumatoid factor by intestinal lamina propria mononuclear cells from Crohn's disease but not ulcerative colitis patientsClinical and Experimental Immunology.  92:152-157. 1993
1993 Molecular and cellular mechanisms of joint destruction in rheumatoid arthritis: Two cellular mechanisms explain joint destruction?Annals of the Rheumatic Diseases.  52. 1993
1993 New approaches to the therapy of autoimmune diseases: Rheumatoid arthritis as a paradigmAmerican Journal of the Medical Sciences.  305:40-48. 1993
1993 Nonperipheral accelerated nodulosis in a methotrexate‐treated rheumatoid arthritis patientArthritis and Rheumatism.  36:132-133. 1993
1993 The use of monozygotic and dizygotic twins to estimate the effects of inheritance on the levels of immunoglobulin isotypes and antibodies to phosphocholineClinical immunology and immunopathology.  66:176-180. 1993
1993 Use of a chimeric monoclonal anti‐CD4 antibody in patients with refractory rheumatoid arthritisArthritis and Rheumatism.  36:307-318. 1993
1992 Abnormal galactosylation of serum IgG in patients with systemic lupus erythematosus and members of families with high frequency of autoimmune diseasesRheumatology International.  12:191-194. 1992
1992 Scanning electron microscopic evaluation of the arthritis in MRL/lpr miceRheumatology International.  12:115-120. 1992
1992 A rheumatoid factor from a normal individual encoded by V H 2 and V k II gene segmentsArthritis and Rheumatism.  35:900-904. 1992
1992 Controlled trial of methotrexate versus 10-deazaaminopterin in the treatment of rheumatoid arthritisAnnals of the Rheumatic Diseases.  51:600-603. 1992
1992 Digital subtraction radiography for the assessment of bone changes in rheumatoid arthritisJournal of Rheumatology.  19:1697-1703. 1992
1992 Efficacy and safety of 10‐deazaaminopterin in the treatment of rheumatoid arthritis: A one‐year continuation, double‐blind studyArthritis and Rheumatism.  35:1318-1321. 1992
1992 Expressing our inner thoughts: How to organize and write a clinical research project grant applicationJournal of Rheumatology.  19:16-19. 1992
1992 Infection as a cause of reactive arthritis, ankylosing spondylitis, and rheumatic feverCurrent Opinion in Rheumatology.  4:534-542. 1992
1992 Local immune responses in certain extra-articular manifestations of rheumatoid arthritisAnnals of the Rheumatic Diseases.  51:698-701. 1992
1992 Long-term treatment of the MRL/lpr mouse with methotrexate and 10-deazaaminopterinAgents and actions.  35:104-111. 1992
1992 The immunoglobulin kappa light chain repertoire expressed in the synovium of a patient with rheumatoid arthritisArthritis and Rheumatism.  35:905-913. 1992
1991 Apolipoprotein A-I decreases neutrophil degranulation and superoxide productionJournal of Lipid Research.  32:1911-1918. 1991
1991 Infection as a cause of arthritisCurrent Opinion in Rheumatology.  3:639-649. 1991
1991 RheumatologyJournal of the American Medical Association.  265:3169-3170. 1991
1991 Cellular origins of human polymeric and monomeric IgA: enumeration of single cells secreting polymeric IgA1 and IgA2 in peripheral blood, bone marrow, spleen, gingiva and synovial tissueClinical and Experimental Immunology.  85:341-348. 1991
1991 Genetic studies of four highly homologous rheumatoid factor-associated Vk genes in rheumatoid arthritis patients and normal individualsMolecular Immunology.  28:1073-1083. 1991
1991 In search of Mr. Wizard. Presidential address to the American Society for Clinical Investigation, Seattle, Washington, 4 May 1991Journal of Clinical Investigation.  88:1063-1066. 1991
1991 Local iga and igm rheumatoid factor production in autoimmune MRL/ipr miceAutoimmunity.  10:7-14. 1991
1991 ReplyArthritis and Rheumatism.  34:120-121. 1991
1991 The American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the hipArthritis and Rheumatism.  34:505-514. 1991
1990 Occurrence of a rheumatoid factor cross-reactive kappa light-chain idiotope in rheumatoid arthritis familiesRheumatology International.  10:211-215. 1990
1990 Methotrexate therapy in rheumatoid arthritis patients diminishes lectin-induced mononuclear cell proliferationRheumatology International.  10:165-169. 1990
1990 Achieving consensus on an algorithm for the treatment of rheumatoid arthritis with MethotrexateArthritis and Rheumatism.  3:53-58. 1990
1990 Achieving consensus on an algorithm for the treatment of rheumatoid arthritis with methotrexateArthritis and Rheumatism.  3:53-57. 1990
1990 Correlation of serologic indicators of inflammation with effectiveness of nonsteroidal antiinflammatory drug therapy in rheumatoid arthritisArthritis and Rheumatism.  33:19-28. 1990
1990 Dissociation of expression of two rheumatoid factor cross-reactive κ L chain idiotopes in rheumatoid arthritisJournal of Immunology.  144:3468-3472. 1990
1990 Elucidating the pathogenesis of autoimmune disease: recent advances at the molecular level and relevance to oral mucosal diseaseJournal of Oral Pathology and Medicine.  19:341-350. 1990
1990 Lupus‐inducing drugs alter the structure of supercoiled circular dna domainsArthritis and Rheumatism.  33:366-374. 1990
1990 Monoclonal antibody 6b6.6 defines a cross‐reactive kappa light chain idiotope on human monoclonal and polyclonal rheumatoid factorsArthritis and Rheumatism.  33:187-198. 1990
1990 Osteoarthritis: Definitions and criteriaAnnals of the Rheumatic Diseases.  49:201. 1990
1990 Rheumatoid factor and human diseaseClinical Immunology Newsletter.  10:137-141. 1990
1990 Structural characterization of the second major cross‐reactive idiotype group of human rheumatoid factors. Association with the VH4 Gene FamilyArthritis and Rheumatism.  33:1347-1360. 1990
1990 Suppression of rheumatoid factor production by methotrexate in patients with rheumatoid arthritis: Evidence for differential influences of therapy and clinical status on IgM and IgA rheumatoid factor expressionArthritis and Rheumatism.  33:1156-1161. 1990
1990 Synergism of interleukin 7 with the thymocyte growth factors interleukin 2, interleukin 6, and tumor necrosis factor α in the induction of thymocyte proliferationCellular Immunology.  127:470-482. 1990
1990 The American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the handArthritis and Rheumatism.  33:1601-1610. 1990
1989 The replyAmerican Journal of Medicine.  86:634. 1989
1989 Local production of IgA- and IgM-rheumatoid factors in adult periodontal diseaseJournal of Clinical Immunology.  9:273-278. 1989
1989 Valvular Heart Disease in Systemic Lupus ErythematosusNew England Journal of Medicine.  320:739-741. 1989
1989 AS and a 9.2 kb Pvu II class I HLA DNA restriction fragment.Journal of Rheumatology.  16:141-142. 1989
1989 Analysis of human IgG and IgA subclass antibody-secreting cells from localized chronic inflammatory tissueJournal of Immunology.  142:1150-1158. 1989
1989 Comment on the article by Tomana et alArthritis and Rheumatism.  32:235-236. 1989
1989 Enhancement of IL-2-induced T cell proliferation by a novel factor(s) present in murine spleen dendritic cell-T cell culture supernatantsJournal of Immunology.  142:1183-1194. 1989
1989 Exquisite sensitivity of dendritic cells to ultraviolet radiation and temperature changesTransplantation.  48:666-671. 1989
1989 Identification of peptide hormones of the amphipathic helix class using the helical hydrophobic moment algorithmProteins.  6:61-69. 1989
1989 Immunopathology of rheumatoid arthritisCurrent Opinion in Rheumatology.  1:8-14. 1989
1989 Interleukins and IgA synthesis. Human and murine interleukin 6 induce high rate IgA secretion in IgA-committed B cellsJournal of Experimental Medicine.  169:2133-2148. 1989
1989 Methotrexate-induced liver abnormalities in rheumatoid arthritisJournal of Rheumatology.  16:1180-1183. 1989
1989 Molecular analysis of HLA‐D region genes in seropositive rheumatoid arthritisTissue Antigens.  34:299-308. 1989
1989 Mucosal homeostasis: Role of interleukins, isotype-specific factors and contrasuppression in the iga responseImmunological communications.  18:77-89. 1989
1989 Radiologic assessment as an outcome measure in rheumatoid arthritisArthritis and Rheumatism.  32:221-229. 1989
1989 Secretion of antibodies to types I and II collagen by synovial tissue cells in patients with rheumatoid arthritisArthritis and Rheumatism.  32:1087-1092. 1989
1989 Severe reversible interstitial pneumonitis induced by low dose methotrexateJournal of Rheumatology.  16:1007-1008. 1989
1989 Viral arthritis in humansCurrent Opinion in Rheumatology.  1:185-193. 1989
1988 Molecular genetic studies of rheumatoid arthritisAmerican Journal of Medicine.  85:23-25. 1988
1988 Restriction fragment length polymorphism analysis in ankylosing spondylitisAmerican Journal of Medicine.  85:48-50. 1988
1988 Occurrence of polymeric IgA1 rheumatoid factor in the acquired immune deficiency syndromeJournal of Clinical Immunology.  8:390-396. 1988
1988 Abnormal glycosylation of serum igg from patients with chronic inflammatory diseasesArthritis and Rheumatism.  31:333-338. 1988
1988 Autoimmunity to collagen in adult periodontal diseaseJournal of Oral Pathology and Medicine.  17:456-459. 1988
1988 Clinically significant valvular heart disease in systemic lupus erythematosusAmerican Journal of Medicine.  85:645-650. 1988
1988 Etiopathogenesis of rheumatoid arthritis-like disease in MRL/1 mice: II. Ultrastructural basis of joint destructionJournal of Rheumatology.  15:10-16. 1988
1988 Features of renal vasculitis in autoimmune MRL 1pr/1pr mice: Phenotypes and functional properties of infiltrating cellsClinical and Experimental Immunology.  72:91-97. 1988
1988 Incidence of three cross-reactive idiotypes on human rheumatoid factor paraproteinsJournal of Immunology.  140:3411-3418. 1988
1988 Occurrence of a μchain idiotope in two human monoclonal RF which also share a κchain idiotopeScandinavian Journal of Rheumatology.  17:102-108. 1988
1988 Re: Methotrexate in the treatment of arthritis and connective tissue diseaseCleveland Clinic Journal of Medicine.  55:279. 1988
1988 Recombinant murine IL-5 induces high rate IgA synthesis in cycling IgA-positive Peyer's patch B cellsJournal of Immunology.  141:2035-2042. 1988
1988 Rheumatoid factor diversityIn Vivo.  2:73-78. 1988
1988 The MRL-ipr/ipr mouse. A model for the study of rheumatoid arthritisScandinavian Journal of Rheumatology.  17:284-289. 1988
1988 Ultrastructural study of Sjögren's syndrome‐like disease in MRM miceJournal of Oral Pathology and Medicine.  17:460-465. 1988
1987 Analysis of restriction fragment length polymorphisms in rheumatic diseasesRheumatic Disease Clinics of North America.  13:353-367. 1987
1987 Specificity of monoclonal anti-Z-DNA antibodies from unimmunized MRL/Mp-lpr/lpr miceJournal of Immunology.  139:743-748. 1987
1987 Streptococcal serotype carbohydrate represents a novel class of type 2 antigen which is T-independentJournal of Immunology.  138:4387-4394. 1987
1987 Toxicity to methotrexate in rheumatoid arthritisJournal of Rheumatology.  14:74-79. 1987
1987 Enhanced in vitro IgM rheumatoid factor synthesis in seropositive rheumatoid arthritis familiesRheumatology International.  7:71-75. 1987
1987 Analysis of paraprotein transport into the saliva by using anti-idiotype antibodiesJournal of Immunology.  138:435-439. 1987
1987 Acute cryoglobulinemic renal failure after intravenous infusion of gamma globulinAmerican Journal of Medicine.  82:624-629. 1987
1987 Toxicity due to remission inducing drugs in RA.Journal of Rheumatology.  14:175-176. 1987
1987 A low molecular weight, heat‐labile factor enhances neutrophil fc receptor–mediated lysosomal enzyme release and phagocytosisArthritis and Rheumatism.  30:1006-1014. 1987
1987 Airways disease in rheumatoid arthritis patientsArthritis and Rheumatism.  30:249-256. 1987
1987 Analyses of hla linkage in white families with multiple cases of seropositive rheumatoid arthritisArthritis and Rheumatism.  30:1115-1123. 1987
1987 Association of a 9.2‐kilobase pvu ii class i major histocompatibility complex restriction fragment length polymorphism with ankylosing spondylitisArthritis and Rheumatism.  30:894-900. 1987
1987 Development of clinical criteria for osteoarthritisJournal of Rheumatology.  14:3-6. 1987
1987 Differential expression of IgA- and IgM-rheumatoid factors in human disease: evidence for independent regulation of rheumatoid factor isotype production.Advances in Experimental Medicine and Biology.  216 B:1627-1639. 1987
1987 Humoral sensitivity to native collagen types I-VI in the arthritis of MRL I miceClinical immunology and immunopathology.  45:63-69. 1987
1987 Immunological studies of IgA nephropathy: familial and racial aspects.Advances in Experimental Medicine and Biology.  216 B:1489-1498. 1987
1987 Lack of association between hla–dr2 and clinical response to methotrexate in patients with rheumatoid arthritisArthritis and Rheumatism.  30:218-220. 1987
1987 Review of the national arthritis advisory board symposium, “molecular biology: its potential for advancing rheumatology research”Arthritis and Rheumatism.  30:1191-1194. 1987
1987 Striking Elevation of Serum IgA, IgA-Containing Immune Complexes, and IgA Rheumatoid Factor in Clinically Silent Dermatitis HerpetiformisAmerican Journal of Kidney Diseases.  10:378-384. 1987
1986 VH Gene expression is restricted in anti-igG antibodies from MRL autoimmune miceJournal of Experimental Medicine.  164:1284-1300. 1986
1986 HLA antigens and gold toxicity in American blacks with rheumatoid arthritisRheumatology International.  6:13-17. 1986
1986 Circulating immune complexes and immunoglobulin A rheumatoid factor in patients with mesangial immunoglobulin A nephropathiesJournal of Clinical Investigation.  77:1931-1938. 1986
1986 DR2 positivity and response to methotrexate in rheumatoid arthritisArthritis and Rheumatism.  29:151-151. 1986
1986 Development of criteria for the classification and reporting of osteoarthritis: Classification of osteoarthritis of the kneeArthritis and Rheumatism.  29:1039-1049. 1986
1986 Induction of neutrophil enzyme release by rheumatoid factors: Evidence for differences based on molecular characteristicsClinical immunology and immunopathology.  40:347-355. 1986
1986 Interleukin 1-like factor produced by a hybrid of an adherent mouse spleen cell and a thymoma cellImmunology Letters.  13:143-149. 1986
1986 Molecular forms of IgA rheumatoid factor in serum and synovial fluid of patients with rheumatoid arthritisArthritis and Rheumatism.  29:1194-1202. 1986
1986 Rheumatoid arthritis associated with expanded populations of granular lymphocytesAnnals of Internal Medicine.  104:314-323. 1986
1985 Interaction of DNA with connective tissue matrix proteins reveals preferential binding to type V collagenJournal of Immunology.  135:1097-1100. 1985
1985 Activity of rheumatoid factors of different molecular sizes: Comparison of autologous monomeric and polymeric monoclonal IgA rheumatoid factorsJournal of Immunology.  134:1469-1474. 1985
1985 Comment on letter by Alarcón et alArthritis and Rheumatism.  28:1439-1440. 1985
1985 Etiopathogenesis of the rheumatoid arthritis–like disease in MRL/1 mice. I. The histomorphologic basis of joint destructionArthritis and Rheumatism.  28:529-536. 1985
1985 HLA‐Bw35 and gold toxicity in rheumatoid arthritisArthritis and Rheumatism.  28:236-237. 1985
1985 IgA rheumatoid factor synthesis by dissociated synovial cells. Characterization and relationship to IgM rheumatoid factor synthesisArthritis and Rheumatism.  28:1219-1227. 1985
1985 IgA-IgG immune complexes and rheumatoid factor in IgA nephropathyFederation proceedings.  44. 1985
1985 Immunoglobulin subclass distribution of synovial plasma cells in rheumatoid arthritis determined by use of monoclonal anti-subclass antibodiesClinical immunology and immunopathology.  35:346-351. 1985
1985 In vitro IgM and IgM rheumatoid factor production and response to remittive agents in rheumatoid arthritisArthritis and Rheumatism.  28:356-357. 1985
1985 Production of immunoglobulin and rheumatoid factor by lymphoid cells in rheumatoid pericardiumArthritis and Rheumatism.  28:1071-1074. 1985
1985 Solid-phase radioimmunoassay for human neutrophil elastase: A sensitive method for determining secreted and cell-associated enzymeAnalytical Biochemistry.  150:18-25. 1985
1985 The carpometacarpal ratio: A useful method for assessing disease progression in rheumatoid arthritisJournal of Rheumatology.  12:846-848. 1985
1985 [8] Antiisotypic antibodiesMethods in Enzymology.  116:146-156. 1985
1984 Isotype-specificity of helper T cell clones: Fcα receptors regulate T and B cell collaboration for IgA responsesJournal of Immunology.  133:1087-1089. 1984
1984 Preferential induction of polyclonal IgA secretion by murine peyer’s patch dendritic cell-T cell mixturesJournal of Experimental Medicine.  160:941-946. 1984
1984 In vitro synthesis of IgM and IgM rheumatoid factor in seronegative arthritidesRheumatology International.  4:49-53. 1984
1984 Isotype specificity of helper T cell clones peyer’s patch Th cells preferentially collaborate with mature IgA B cells for IgA responsesJournal of Experimental Medicine.  159:798-811. 1984
1984 Dr Antigens and Gold Toxicity in white rheumatoid arthritis patientsArthritis and Rheumatism.  27:601-605. 1984
1984 Effects of ultraviolet light and interleukin-1 on dendritic cell functionFederation proceedings.  43. 1984
1984 Mucosal Immunoregulation: Environmental Lipopolysaccharide and GALT T Lymphocytes Regulate the IgA ResponseMicrobiology and Immunology.  28:261-280. 1984
1984 Partial characterisation of the high and low molecular weight forms of P388D1‐derived interleukin 1Journal of Cellular Biochemistry.  26:65-73. 1984
1984 Penicillamine-induced Myositis. Observations and unique features in two patients and review of the literatureAmerican Journal of Medicine.  77:719-722. 1984
1984 Peyer's Patch Dendritic Cells: Isolation and Functional Comparison with Murine Spleen Dendritic CellsImmunobiology.  168:380-390. 1984
1984 Rheumatoid myositisArthritis and Rheumatism.  27:737-743. 1984
1983 Local synthesis of IgM and IgM rheumatoid factor in rheumatoid pleuritisJournal of Rheumatology.  10:204-209. 1983
1983 DR antigen distribution in blacks with rheumatoid arthritisJournal of Rheumatology.  10:579-583. 1983
1983 Accessory cells in Murine Peyer’s patch: I. Identification and enrichment of a functional dendritic cellJournal of Experimental Medicine.  157:1646-1659. 1983
1983 CREG antigens differentially influence expression of extraarticular manifestations in whites and blacks with rheumatoid arthritisSeminars in Arthritis and Rheumatism.  13:169-173. 1983
1983 IDENTIFICATION OF A NONADHERENT ACCESSORY CELL IN MURINE PEYER'S PATCHESAnnals of the New York Academy of Sciences.  409:880-881. 1983
1983 IgA RHEUMATOID FACTOR: EVIDENCE FOR INDEPENDENT EXPRESSION AT LOCAL SITES OF TISSUE INFLAMMATIONAnnals of the New York Academy of Sciences.  409:258-272. 1983
1983 Lymphoid Cell Responses to Bacterial Cell Wall Components: Murine B‐Cell Responses to a Purified Cell Wall Moiety of ActinomycesScandinavian Journal of Immunology.  17:313-322. 1983
1983 MURINE PEYER'S PATCH T‐HELPER CELL CLONES THAT PREFERENTIALLY SUPPORT IgA RESPONSESAnnals of the New York Academy of Sciences.  409:829-830. 1983
1983 PEYER'S PATCH ACCESSORY CELLS BEAR I‐AAnnals of the New York Academy of Sciences.  409:819-821. 1983
1983 REGULATION OF IgA SUBCLASSES IN POKEWEED MITOGEN STIMULATED CULTURESAnnals of the New York Academy of Sciences.  409:797-798. 1983
1983 Seronegative rheumatoid arthritis and b7‐creg: disparate resultsArthritis and Rheumatism.  26:1412-1413. 1983
1983 Serum IgA1 and IgA2 in normal adults and patients with systemic lupus erythematosus and hepatic diseaseClinical immunology and immunopathology.  26:390-397. 1983
1983 Suppression of in vitro monoclonal human rheumatoid factor synthesis by antiidiotypic antibody. Target cells and molecular requirementsJournal of Clinical Investigation.  72:1410-1419. 1983
1983 THE IgA RESPONSE: INDUCTIVE ASPECTS, REGULATORY CELLS, AND EFFECTOR FUNCTIONSAnnals of the New York Academy of Sciences.  409:48-71. 1983
1982 In vitro regulation of IgA subclass synthesis: I. Discordance between plasma cell production and antibody secretionJournal of Experimental Medicine.  156:1615-1621. 1982
1982 Murine peyer’s patch T cell clones: Characterization of antigen-specific helper T cells for immunoglobulin a responsesJournal of Experimental Medicine.  156:1115-1130. 1982
1982 A quantitative assay for IgA rheumatoid factorJournal of Immunological Methods.  50:89-98. 1982
1982 Buffer electrofocusing of Interleukin IBioscience Reports.  2:241-246. 1982
1982 An enzymatic method for preparation of dissociated murine Peyer's patch cells enriched for macrophagesJournal of Immunological Methods.  48:33-44. 1982
1982 Differential patterns of in vitro IgM rheumatoid factor synthesis in seronegative and seropositive rheumatoid arthritisArthritis and Rheumatism.  25:150-155. 1982
1982 Seronegative rheumatoid arthritis.Arthritis and Rheumatism.  25:502-507. 1982
1981 Lymphoid cell responses to bacterial cell wall components: Polyclonal and immune responses of murine B cells to Streptococcus mutans carbohydrate antigensJournal of Immunology.  127:2106-2112. 1981
1981 Interleukin 1: Production by P388D1 cells attached to microcarrier beadsJournal of Immunological Methods.  46:197-204. 1981
1981 Suppressor T Cells Prevent in Vitro Expression of IgM Rheumatoid Factor in Some Healthy AdultsProceedings of the Society for Experimental Biology and Medicine.  168:344-349. 1981
1980 Production of predominantly polymeric IgA by human peripheral blood lymphocytes stimulated in vitro with mitogensJournal of Experimental Medicine.  152:1424-1429. 1980
1980 A sensitive radioimmunoassay for quantitation of igm rheumatoid factorArthritis and Rheumatism.  23:302-308. 1980
1980 Enhanced in vitro synthesis of igm rheumatoid factor in rheumatoid arthritisArthritis and Rheumatism.  23:985-992. 1980
1980 In vitro synthesis of IgM rheumatoid factor by lymphocytes from healthy adultsJournal of Immunology.  125:934-938. 1980

Education And Training

  • Doctor of Medicine in Immunology, Harvard University 1972
  • Full Name

  • William Koopman