Positions

Selected Publications

Academic Article

Year Title Altmetric
2020 Georgia Abortion Law and Our Commitment to PatientsArthritis and Rheumatology.  72:377-378. 2020
2008 Dawn of the era of biologics in the treatment of the rheumatic diseasesArthritis and Rheumatism.  58. 2008
2005 Cleavage of p53-vimentin complex enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis of rheumatoid arthritis synovial fibroblastsAmerican Journal of Pathology.  167:705-719. 2005
2004 Presentation of the 2004 Founders' Medal to J. Claude Bennett, MD.American Journal of the Medical Sciences.  328:251-253. 2004
2003 FcγRs modulate cytotoxicity of anti-Fas antibodies: Implications for agonistic antibody-based therapeuticsJournal of Immunology.  171:562-568. 2003
2003 TRAIL-R2 (DR5) mediates apoptosis of synovial fibroblasts in rheumatoid arthritisJournal of Immunology.  171:1061-1069. 2003
2002 Folic acid and folinic acid supplementation during low-dose methotrexate therapy for rheumatoid arthritis: Comment on the article by van Ede et al [6]Arthritis and Rheumatism.  46:1413-1414. 2002
2001 Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicityNature Medicine.  7:954-960. 2001
2001 Prospects for autoimmune disease: Research advances in rheumatoid arthritis 2001
1998 T cell receptor peptide vaccination in rheumatoid arthritis: A placebo- controlled trial using a combination of V(β)3, V(β)14, and V(β)17 peptidesArthritis and Rheumatism.  41:1919-1929. 1998
1998 In situ hybridization analysis of immunoglobulin heavy chain variable gene expression with family specific oligonucleotide probesJournal of Immunological Methods.  218:31-52. 1998
1998 The effect of methotrexate and 7-hydroxymethotrexate on rat adjuvant arthritis and on urinary aminoimidazole carboxamide excretionArthritis and Rheumatism.  41:1407-1410. 1998
1998 Enhanced expression of immunoglobulin κ light chains with unusually long CDR3 regions in patients with rheumatoid arthritisJournal of Rheumatology.  25:1067-1071. 1998
1998 Nondepleting humanized anti-CD4 monoclonal antibody in patients with refractory rheumatoid arthritisJournal of Rheumatology.  25:221-228. 1998
1998 Rheumatoid arthritis: Anticytokine therapies on the horizonAnnals of Internal Medicine.  128:231-233. 1998
1998 Clonally-related immunoglobulin V(H) domains and nonrandom use of D(H) gene segments in rheumatoid arthritis synoviumMolecular Medicine.  4:240-257. 1998
1998 Dendritic cells from Peyer's patch and spleen induce different T helper cell responsesJournal of Interferon and Cytokine Research.  18:103-115. 1998
1997 Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion proteinNew England Journal of Medicine.  337:141-147. 1997
1997 Biologic agents for treating rheumatoid arthritis: Concepts and progressArthritis and Rheumatism.  40:397-409. 1997
1997 Vaccination against rheumatoid arthritis. Concepts and progress 1997
1996 In situ hybridization and QC-RT-PCR analysis of arthroscopic biopsies of early rheumatoid arthritis synovial tissueThe FASEB Journal.  10. 1996
1996 Recombinant soluble tumor necrosis factor receptor (p80) fusion protein: Toxicity and dose finding trial in refractory rheumatoid arthritisJournal of Rheumatology.  23:1849-1855. 1996
1996 Suppression of in vitro IgM rheumatoid factor production by diphtheria toxin interleukin 2 recombinant fusion protein (DAB 486IL-2) in patients with refractory rheumatoid arthritisJournal of Rheumatology.  23:1845-1848. 1996
1996 Vβ17 T cell receptor peptide vaccination in rheumatoid arthritis: Results of phase I dose escalation studyJournal of Rheumatology.  23:1353-1362. 1996
1996 Dendritic cells from different tissues induce production of different T cell cytokine profilesJournal of Leukocyte Biology.  59:494-498. 1996
1996 Editorial overview: Rheumatoid arthritisCurrent Opinion in Rheumatology.  8:201-202. 1996
1996 Quantitative analysis of immunoglobulin Vκ CDR3 lengths in rheumatoid arthritis: Evidence of antigenic selection or dysregulation of gene rearrangementJournal of Investigative Medicine.  44. 1996
1995 Identifying nursing research priorities: general and neuroscience specific at an acute care hospital. 1995
1995 Regeneration of t cells after chemotherapyNew England Journal of Medicine.  332:1650-1652. 1995
1995 Analysis of Immunoglobulin Gamma Heavy Chains from Rheumatoid Arthritis Synovium Evidence of Antigen‐Driven SelectionAnnals of the New York Academy of Sciences.  764:450-460. 1995
1995 Characterization of human Fas gene: Exon/intron organization and promoter regionJournal of Immunology.  154:1239-1245. 1995
1995 Dendritic cells regulate development of alloantigenic and mitogenic T(H)1 versus T(H)2 responsesAdvances in Experimental Medicine and Biology.  378:347-349. 1995
1995 Double‐blind, placebo‐controlled multicenter trial using chimeric monoclonal anti‐cd4 antibody, cm‐t412, in rheumatoid arthritis patients receiving concomitant methotrexateArthritis and Rheumatism.  38:1581-1588. 1995
1995 Immunoglobulin gene expression in rheumatoid arthritisAgents and actions. Supplements.  47:23-35. 1995
1995 In Situ Hybridization Analysis of Immunoglobulin VH Gene Family Expression in Rheumatoid ArthritisAnnals of the New York Academy of Sciences.  764:453-456. 1995
1995 Interleukin‐2 diphtheria fusion protein (dab486il‐2) in refractory rheumatoid arthritis a double‐blind, placebo‐controlled trial with open‐label extensionArthritis and Rheumatism.  38:1177-1186. 1995
1995 Molecular characterization of monoclonal igm derived from human b cell lines expressing the 4c9 rheumatoid factor associated idiotypeAutoimmunity.  20:171-183. 1995
1995 Progressive joint destruction in a human immunodeficiency virus‐infected patient with rheumatoid arthritisArthritis and Rheumatism.  38:1328-1332. 1995
1995 Rheumatoid arthritis: Editorial overviewCurrent Opinion in Rheumatology.  7:199-200. 1995
1995 Somatic mutation and CDR3 lengths of immunoglobulin κ light chains expressed in patients with rheumatoid arthritis and in normal individualsJournal of Clinical Investigation.  96:831-841. 1995
1995 Synovial biopsy of the knee joint under direct visualization by needle arthroscopy 1995
1995 Vβ17 T‐Cell Receptor Peptide Vaccine: Results of a Phase I Dose‐Finding Study in Patients with Rheumatoid ArthritisAnnals of the New York Academy of Sciences.  756:211-214. 1995
1994 Supplementation with folic acid during methotrexate therapy for rheumatoid arthritis: A double-blind, placebo-controlled trialAnnals of Internal Medicine.  121:833-841. 1994
1994 Overexpression of zinc-finger transcription factor Z-225/Egr-1 in synoviocytes from rheumatoid arthritis patientsJournal of Immunology.  152:5940-5948. 1994
1994 Human rheumatoid factors with restrictive specificity for rabbit immunoglobulin G: Auto- and multi-reactivity, diverse VH gene segment usage and preferential usage of VλIIlbJournal of Experimental Medicine.  179:1445-1456. 1994
1994 Occurrence of deficient galactosylation of serum IgG prior to the onset of rheumatoid arthritis 1994
1994 Erratum: Overexpression of zinc-finger transcription factor Z-225/Egr-1 in synoviocytes from rheumatoid arthritis patients (Blood (June 15, 1994) 152:12 (5940))Journal of Immunology.  153:5347. 1994
1994 Evidence of antigen receptor-influenced oligoclonal B lymphocyte expansion in the synovium of a patient with longstanding rheumatoid arthritisJournal of Clinical Investigation.  93:361-370. 1994
1994 Expression of rheumatoid factor idiotypes 17.109, 6b6.6 and 4c9 in the sera of pima indiansAutoimmunity.  18:251-258. 1994
1994 HLA in ankylosing spondylitis: Is HLA-B27 the only MHC gene involved in disease pathogenesis?Seminars in Arthritis and Rheumatism.  23:295-309. 1994
1994 Leucovorin Versus Folic Acid in the Treatment of Methotrexate Toxicity: Comment on the Article by Shiroky et a1Arthritis and Rheumatism.  37:444-444. 1994
1994 Survival impact of autoantibodies in systemic lupus erythematosusJournal of Rheumatology.  21:224-228. 1994
1994 T Cell Influence on Superantigen‐Induced Arthritis in MRL‐lpr/lpr MiceArthritis and Rheumatism.  37:113-124. 1994
1994 The future of biologies in the treatment of rheumatoid arthritisSeminars in Arthritis and Rheumatism.  23:50-58. 1994
1994 Treatment of refractory rheumatoid arthritis with a chimeric ANTI‐CD4 monoclonal antibodyArthritis and Rheumatism.  37:834-838. 1994
1993 Analysis of immunoglobulin gamma heavy chain expression in synovial tissue of a patient with rheumatoid arthritisArthritis and Rheumatism.  36:631-641. 1993
1993 Anticardiolipin antibodies in systemic lupus erythematosus: Clinical correlates, HLA associations, and impact on survivalJournal of Rheumatology.  20:1684-1693. 1993
1993 Antifolates in rheumatoid arthritis: A hypothetical mechanism of actionClinical and Experimental Rheumatology.  11. 1993
1993 Divergent T-cell cytokine profiles induced by dendritic cells from different tissuesAdvances in Experimental Medicine and Biology.  329:47-53. 1993
1993 Do nonimmunologically mediated pathways play a role in the pathogenesis of rheumatoid arthritis?Rheumatic Disease Clinics of North America.  19:107-122. 1993
1993 Effects of Nonsteroidal Antiinflammatory Drugs on Bone Loss in Chronic Inflammatory DiseaseAnnals of the New York Academy of Sciences.  696:292-302. 1993
1993 Experience with a chimeric monoclonal anti-CD4 antibody in the treatment of refractory rheumatoid arthritisClinical and Experimental Rheumatology.  11. 1993
1993 Folate supplementation and methotrexate [3]Annals of the Rheumatic Diseases.  52:315-316. 1993
1993 Host factors in the pathogenesis of arthritis triggered by infectious organismsRheumatic Disease Clinics of North America.  19:279-292. 1993
1993 Increased spontaneous secretion of rheumatoid factor by intestinal lamina propria mononuclear cells from Crohn's disease but not ulcerative colitis patientsClinical and Experimental Immunology.  92:152-157. 1993
1993 Molecular and cellular mechanisms of joint destruction in rheumatoid arthritis: Two cellular mechanisms explain joint destruction?Annals of the Rheumatic Diseases.  52. 1993
1993 New approaches to the therapy of autoimmune diseases: Rheumatoid arthritis as a paradigmAmerican Journal of the Medical Sciences.  305:40-48. 1993
1993 Nonperipheral accelerated nodulosis in a methotrexate‐treated rheumatoid arthritis patientArthritis and Rheumatism.  36:132-133. 1993
1993 The use of monozygotic and dizygotic twins to estimate the effects of inheritance on the levels of immunoglobulin isotypes and antibodies to phosphocholineClinical immunology and immunopathology.  66:176-180. 1993
1993 Use of a chimeric monoclonal anti‐CD4 antibody in patients with refractory rheumatoid arthritisArthritis and Rheumatism.  36:307-318. 1993
1992 Abnormal galactosylation of serum IgG in patients with systemic lupus erythematosus and members of families with high frequency of autoimmune diseases 1992
1992 Scanning electron microscopic evaluation of the arthritis in MRL/lpr mice 1992
1992 A rheumatoid factor from a normal individual encoded by VH2 and VkII gene segmentsArthritis and Rheumatism.  35:900-904. 1992
1992 Controlled trial of methotrexate versus 10-deazaaminopterin in the treatment of rheumatoid arthritisAnnals of the Rheumatic Diseases.  51:600-603. 1992
1992 Digital subtraction radiography for the assessment of bone changes in rheumatoid arthritisJournal of Rheumatology.  19:1697-1703. 1992
1992 Efficacy and safety of 10‐deazaaminopterin in the treatment of rheumatoid arthritis: A one‐year continuation, double‐blind studyArthritis and Rheumatism.  35:1318-1321. 1992
1992 Expressing our inner thoughts: How to organize and write a clinical research project grant applicationJournal of Rheumatology.  19:16-19. 1992
1992 Infection as a cause of reactive arthritis, ankylosing spondylitis, and rheumatic feverCurrent Opinion in Rheumatology.  4:534-542. 1992
1992 Local immune responses in certain extra-articular manifestations of rheumatoid arthritisAnnals of the Rheumatic Diseases.  51:698-701. 1992
1992 Long-term treatment of the MRL/lpr mouse with methotrexate and 10-deazaaminopterinAgents and actions.  35:104-111. 1992
1992 The immunoglobulin kappa light chain repertoire expressed in the synovium of a patient with rheumatoid arthritisArthritis and Rheumatism.  35:905-913. 1992
1991 Apolipoprotein A-I decreases neutrophil degranulation and superoxide productionJournal of Lipid Research.  32:1911-1918. 1991
1991 Rheumatology 1991
1991 Cellular origins of human polymeric and monomeric IgA: enumeration of single cells secreting polymeric IgA1 and IgA2 in peripheral blood, bone marrow, spleen, gingiva and synovial tissueClinical and Experimental Immunology.  85:341-348. 1991
1991 Genetic studies of four highly homologous rheumatoid factor-associated Vk genes in rheumatoid arthritis patients and normal individualsMolecular Immunology.  28:1073-1083. 1991
1991 In search of Mr. Wizard. Presidential address to the American Society for Clinical Investigation, Seattle, Washington, 4 May 1991Journal of Clinical Investigation.  88:1063-1066. 1991
1991 Infection as a cause of arthritisCurrent Opinion in Rheumatology.  3:639-649. 1991
1991 Local iga and igm rheumatoid factor production in autoimmune MRL/ipr miceAutoimmunity.  10:7-14. 1991
1991 ReplyArthritis and Rheumatism.  34:120-121. 1991
1991 The American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the hipArthritis and Rheumatism.  34:505-514. 1991
1990 Occurrence of a rheumatoid factor cross-reactive kappa light-chain idiotope in rheumatoid arthritis families 1990
1990 Methotrexate therapy in rheumatoid arthritis patients diminishes lectin-induced mononuclear cell proliferation 1990
1990 Achieving consensus on an algorithm for the treatment of rheumatoid arthritis with MethotrexateArthritis and Rheumatism.  3:53-58. 1990
1990 Achieving consensus on an algorithm for the treatment of rheumatoid arthritis with methotrexateArthritis and Rheumatism.  3:53-57. 1990
1990 Correlation of serologic indicators of inflammation with effectiveness of nonsteroidal antiinflammatory drug therapy in rheumatoid arthritisArthritis and Rheumatism.  33:19-28. 1990
1990 Dissociation of expression of two rheumatoid factor cross-reactive κ L chain idiotopes in rheumatoid arthritisJournal of Immunology.  144:3468-3472. 1990
1990 Elucidating the pathogenesis of autoimmune disease: recent advances at the molecular level and relevance to oral mucosal diseaseJournal of Oral Pathology and Medicine.  19:341-350. 1990
1990 Lupus‐inducing drugs alter the structure of supercoiled circular dna domainsArthritis and Rheumatism.  33:366-374. 1990
1990 Monoclonal antibody 6b6.6 defines a cross‐reactive kappa light chain idiotope on human monoclonal and polyclonal rheumatoid factorsArthritis and Rheumatism.  33:187-198. 1990
1990 Osteoarthritis: Definitions and criteriaAnnals of the Rheumatic Diseases.  49:201. 1990
1990 Rheumatoid factor and human diseaseClinical Immunology Newsletter.  10:137-141. 1990
1990 Structural characterization of the second major cross‐reactive idiotype group of human rheumatoid factors. Association with the VH4 Gene FamilyArthritis and Rheumatism.  33:1347-1360. 1990
1990 Suppression of rheumatoid factor production by methotrexate in patients with rheumatoid arthritis: Evidence for differential influences of therapy and clinical status on IgM and IgA rheumatoid factor expressionArthritis and Rheumatism.  33:1156-1161. 1990
1990 Synergism of interleukin 7 with the thymocyte growth factors interleukin 2, interleukin 6, and tumor necrosis factor α in the induction of thymocyte proliferationCellular Immunology.  127:470-482. 1990
1990 The American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the handArthritis and Rheumatism.  33:1601-1610. 1990
1989 Local production of IgA- and IgM-rheumatoid factors in adult periodontal diseaseJournal of Clinical Immunology.  9:273-278. 1989
1989 Valvular Heart Disease in Systemic Lupus ErythematosusNew England Journal of Medicine.  320:739-741. 1989
1989 AS and a 9.2 kb Pvu II class I HLA DNA restriction fragment.Journal of Rheumatology.  16:141-142. 1989
1989 Analysis of human IgG and IgA subclass antibody-secreting cells from localized chronic inflammatory tissueJournal of Immunology.  142:1150-1158. 1989
1989 Comment on the article by Tomana et alArthritis and Rheumatism.  32:235-236. 1989
1989 Enhancement of IL-2-induced T cell proliferation by a novel factor(s) present in murine spleen dendritic cell-T cell culture supernatantsJournal of Immunology.  142:1183-1194. 1989
1989 Exquisite sensitivity of dendritic cells to ultraviolet radiation and temperature changesTransplantation.  48:666-671. 1989
1989 Identification of peptide hormones of the amphipathic helix class using the helical hydrophobic moment algorithm 1989
1989 Immunopathology of rheumatoid arthritisCurrent Opinion in Rheumatology.  1:8-14. 1989
1989 Interleukins and IgA synthesis. Human and murine interleukin 6 induce high rate IgA secretion in IgA-committed B cellsJournal of Experimental Medicine.  169:2133-2148. 1989
1989 Methotrexate-induced liver abnormalities in rheumatoid arthritisJournal of Rheumatology.  16:1180-1183. 1989
1989 Molecular analysis of HLA‐D region genes in seropositive rheumatoid arthritis 1989
1989 Mucosal homeostasis: Role of interleukins, isotype-specific factors and contrasuppression in the iga response 1989
1989 Radiologic assessment as an outcome measure in rheumatoid arthritisArthritis and Rheumatism.  32:221-229. 1989
1989 Secretion of antibodies to types I and II collagen by synovial tissue cells in patients with rheumatoid arthritisArthritis and Rheumatism.  32:1087-1092. 1989
1989 Severe reversible interstitial pneumonitis induced by low dose methotrexateJournal of Rheumatology.  16:1007-1008. 1989
1989 The replyAmerican Journal of Medicine.  86:634. 1989
1989 Viral arthritis in humansCurrent Opinion in Rheumatology.  1:185-193. 1989
1988 Molecular genetic studies of rheumatoid arthritisAmerican Journal of Medicine.  85:23-25. 1988
1988 Restriction fragment length polymorphism analysis in ankylosing spondylitisAmerican Journal of Medicine.  85:48-50. 1988
1988 Occurrence of polymeric IgA1 rheumatoid factor in the acquired immune deficiency syndromeJournal of Clinical Immunology.  8:390-396. 1988
1988 Abnormal glycosylation of serum igg from patients with chronic inflammatory diseasesArthritis and Rheumatism.  31:333-338. 1988
1988 Autoimmunity to collagen in adult periodontal diseaseJournal of Oral Pathology and Medicine.  17:456-459. 1988
1988 Clinically significant valvular heart disease in systemic lupus erythematosusAmerican Journal of Medicine.  85:645-650. 1988
1988 Etiopathogenesis of rheumatoid arthritis-like disease in MRL/1 mice: II. Ultrastructural basis of joint destructionJournal of Rheumatology.  15:10-16. 1988
1988 Features of renal vasculitis in autoimmune MRL 1pr/1pr mice: Phenotypes and functional properties of infiltrating cellsClinical and Experimental Immunology.  72:91-97. 1988
1988 Incidence of three cross-reactive idiotypes on human rheumatoid factor paraproteinsJournal of Immunology.  140:3411-3418. 1988
1988 LettersArthritis and Rheumatism.  1:65-66. 1988
1988 Occurrence of a μchain idiotope in two human monoclonal RF which also share a κchain idiotopeScandinavian Journal of Rheumatology.  17:102-108. 1988
1988 Re: Methotrexate in the treatment of arthritis and connective tissue diseaseCleveland Clinic Journal of Medicine.  55:279. 1988
1988 Recombinant murine IL-5 induces high rate IgA synthesis in cycling IgA-positive Peyer's patch B cellsJournal of Immunology.  141:2035-2042. 1988
1988 Rheumatoid factor diversity 1988
1988 The MRL-ipr/ipr mouse. A model for the study of rheumatoid arthritisScandinavian Journal of Rheumatology.  17:284-289. 1988
1988 Ultrastructural study of Sjögren's syndrome‐like disease in MRM miceJournal of Oral Pathology and Medicine.  17:460-465. 1988
1987 Analysis of restriction fragment length polymorphisms in rheumatic diseasesRheumatic Disease Clinics of North America.  13:353-367. 1987
1987 Specificity of monoclonal anti-Z-DNA antibodies from unimmunized MRL/Mp-lpr/lpr miceJournal of Immunology.  139:743-748. 1987
1987 Streptococcal serotype carbohydrate represents a novel class of type 2 antigen which is T-independentJournal of Immunology.  138:4387-4394. 1987
1987 Toxicity to methotrexate in rheumatoid arthritisJournal of Rheumatology.  14:74-79. 1987
1987 Enhanced in vitro IgM rheumatoid factor synthesis in seropositive rheumatoid arthritis families 1987
1987 Analysis of paraprotein transport into the saliva by using anti-idiotype antibodiesJournal of Immunology.  138:435-439. 1987
1987 Acute cryoglobulinemic renal failure after intravenous infusion of gamma globulinAmerican Journal of Medicine.  82:624-629. 1987
1987 Toxicity due to remission inducing drugs in RA.Journal of Rheumatology.  14:175-176. 1987
1987 A low molecular weight, heat‐labile factor enhances neutrophil fc receptor–mediated lysosomal enzyme release and phagocytosisArthritis and Rheumatism.  30:1006-1014. 1987
1987 Airways disease in rheumatoid arthritis patientsArthritis and Rheumatism.  30:249-256. 1987
1987 Analyses of hla linkage in white families with multiple cases of seropositive rheumatoid arthritisArthritis and Rheumatism.  30:1115-1123. 1987
1987 Association of a 9.2‐kilobase pvu ii class i major histocompatibility complex restriction fragment length polymorphism with ankylosing spondylitisArthritis and Rheumatism.  30:894-900. 1987
1987 Development of clinical criteria for osteoarthritisJournal of Rheumatology.  14:3-6. 1987
1987 Differential expression of IgA- and IgM-rheumatoid factors in human disease: evidence for independent regulation of rheumatoid factor isotype production.Advances in Experimental Medicine and Biology.  216 B:1627-1639. 1987
1987 Humoral sensitivity to native collagen types I-VI in the arthritis of MRL I miceClinical immunology and immunopathology.  45:63-69. 1987
1987 Immunological studies of IgA nephropathy: familial and racial aspects.Advances in Experimental Medicine and Biology.  216 B:1489-1498. 1987
1987 Lack of association between hla–dr2 and clinical response to methotrexate in patients with rheumatoid arthritisArthritis and Rheumatism.  30:218-220. 1987
1987 Review of the national arthritis advisory board symposium, “molecular biology: its potential for advancing rheumatology research”Arthritis and Rheumatism.  30:1191-1194. 1987
1987 Striking Elevation of Serum IgA, IgA-Containing Immune Complexes, and IgA Rheumatoid Factor in Clinically Silent Dermatitis HerpetiformisAmerican Journal of Kidney Diseases.  10:378-384. 1987
1986 VH Gene expression is restricted in anti-igG antibodies from MRL autoimmune miceJournal of Experimental Medicine.  164:1284-1300. 1986
1986 HLA antigens and gold toxicity in American blacks with rheumatoid arthritis 1986
1986 Circulating immune complexes and immunoglobulin A rheumatoid factor in patients with mesangial immunoglobulin A nephropathiesJournal of Clinical Investigation.  77:1931-1938. 1986
1986 DR2 positivity and response to methotrexate in rheumatoid arthritisArthritis and Rheumatism.  29:151-151. 1986
1986 Development of criteria for the classification and reporting of osteoarthritis: Classification of osteoarthritis of the kneeArthritis and Rheumatism.  29:1039-1049. 1986
1986 Induction of neutrophil enzyme release by rheumatoid factors: Evidence for differences based on molecular characteristicsClinical immunology and immunopathology.  40:347-355. 1986
1986 Interleukin 1-like factor produced by a hybrid of an adherent mouse spleen cell and a thymoma cellImmunology Letters.  13:143-149. 1986
1986 Molecular forms of IgA rheumatoid factor in serum and synovial fluid of patients with rheumatoid arthritisArthritis and Rheumatism.  29:1194-1202. 1986
1986 Rheumatoid arthritis associated with expanded populations of granular lymphocytesAnnals of Internal Medicine.  104:314-323. 1986
1985 Interaction of DNA with connective tissue matrix proteins reveals preferential binding to type V collagenJournal of Immunology.  135:1097-1100. 1985
1985 Activity of rheumatoid factors of different molecular sizes: Comparison of autologous monomeric and polymeric monoclonal IgA rheumatoid factorsJournal of Immunology.  134:1469-1474. 1985
1985 Comment on letter by Alarcón et alArthritis and Rheumatism.  28:1439-1440. 1985
1985 Etiopathogenesis of the rheumatoid arthritis–like disease in MRL/1 mice. I. The histomorphologic basis of joint destructionArthritis and Rheumatism.  28:529-536. 1985
1985 HLA‐Bw35 and gold toxicity in rheumatoid arthritisArthritis and Rheumatism.  28:236-237. 1985
1985 IgA rheumatoid factor synthesis by dissociated synovial cells. Characterization and relationship to IgM rheumatoid factor synthesisArthritis and Rheumatism.  28:1219-1227. 1985
1985 IgA-IgG immune complexes and rheumatoid factor in IgA nephropathyThe FASEB Journal.  44. 1985
1985 Immunoglobulin subclass distribution of synovial plasma cells in rheumatoid arthritis determined by use of monoclonal anti-subclass antibodiesClinical immunology and immunopathology.  35:346-351. 1985
1985 In vitro IgM and IgM rheumatoid factor production and response to remittive agents in rheumatoid arthritisArthritis and Rheumatism.  28:356-357. 1985
1985 Production of immunoglobulin and rheumatoid factor by lymphoid cells in rheumatoid pericardiumArthritis and Rheumatism.  28:1071-1074. 1985
1985 Solid-phase radioimmunoassay for human neutrophil elastase: A sensitive method for determining secreted and cell-associated enzymeAnalytical Biochemistry.  150:18-25. 1985
1985 The carpometacarpal ratio: A useful method for assessing disease progression in rheumatoid arthritisJournal of Rheumatology.  12:846-848. 1985
1985 [8] Antiisotypic antibodiesMethods in Enzymology.  116:146-156. 1985
1984 Isotype-specificity of helper T cell clones: Fcα receptors regulate T and B cell collaboration for IgA responsesJournal of Immunology.  133:1087-1089. 1984
1984 Preferential induction of polyclonal IgA secretion by murine peyer’s patch dendritic cell-T cell mixturesJournal of Experimental Medicine.  160:941-946. 1984
1984 In vitro synthesis of IgM and IgM rheumatoid factor in seronegative arthritides 1984
1984 Isotype specificity of helper T cell clones peyer’s patch Th cells preferentially collaborate with mature IgA B cells for IgA responsesJournal of Experimental Medicine.  159:798-811. 1984
1984 Dr Antigens and Gold Toxicity in white rheumatoid arthritis patientsArthritis and Rheumatism.  27:601-605. 1984
1984 Effects of ultraviolet light and interleukin-1 on dendritic cell functionThe FASEB Journal.  43. 1984
1984 Mucosal Immunoregulation: Environmental Lipopolysaccharide and GALT T Lymphocytes Regulate the IgA ResponseMicrobiology and Immunology.  28:261-280. 1984
1984 Partial characterisation of the high and low molecular weight forms of P388D1‐derived interleukin 1Journal of Cellular Biochemistry.  26:65-73. 1984
1984 Penicillamine-induced Myositis. Observations and unique features in two patients and review of the literatureAmerican Journal of Medicine.  77:719-722. 1984
1984 Peyer's Patch Dendritic Cells: Isolation and Functional Comparison with Murine Spleen Dendritic CellsImmunobiology.  168:380-390. 1984
1984 Rheumatoid myositisArthritis and Rheumatism.  27:737-743. 1984
1983 Local synthesis of IgM and IgM rheumatoid factor in rheumatoid pleuritisJournal of Rheumatology.  10:204-209. 1983
1983 DR antigen distribution in blacks with rheumatoid arthritisJournal of Rheumatology.  10:579-583. 1983
1983 Accessory cells in Murine Peyer’s patch: I. Identification and enrichment of a functional dendritic cellJournal of Experimental Medicine.  157:1646-1659. 1983
1983 CREG antigens differentially influence expression of extraarticular manifestations in whites and blacks with rheumatoid arthritisSeminars in Arthritis and Rheumatism.  13:169-173. 1983
1983 IDENTIFICATION OF A NONADHERENT ACCESSORY CELL IN MURINE PEYER'S PATCHESAnnals of the New York Academy of Sciences.  409:880-881. 1983
1983 IgA RHEUMATOID FACTOR: EVIDENCE FOR INDEPENDENT EXPRESSION AT LOCAL SITES OF TISSUE INFLAMMATIONAnnals of the New York Academy of Sciences.  409:258-272. 1983
1983 Lymphoid Cell Responses to Bacterial Cell Wall Components: Murine B‐Cell Responses to a Purified Cell Wall Moiety of ActinomycesScandinavian Journal of Immunology.  17:313-322. 1983
1983 MURINE PEYER'S PATCH T‐HELPER CELL CLONES THAT PREFERENTIALLY SUPPORT IgA RESPONSESAnnals of the New York Academy of Sciences.  409:829-830. 1983
1983 PEYER'S PATCH ACCESSORY CELLS BEAR I‐AAnnals of the New York Academy of Sciences.  409:819-821. 1983
1983 REGULATION OF IgA SUBCLASSES IN POKEWEED MITOGEN STIMULATED CULTURESAnnals of the New York Academy of Sciences.  409:797-798. 1983
1983 Seronegative rheumatoid arthritis and b7‐creg: disparate resultsArthritis and Rheumatism.  26:1412-1413. 1983
1983 Serum IgA1 and IgA2 in normal adults and patients with systemic lupus erythematosus and hepatic diseaseClinical immunology and immunopathology.  26:390-397. 1983
1983 Suppression of in vitro monoclonal human rheumatoid factor synthesis by antiidiotypic antibody. Target cells and molecular requirementsJournal of Clinical Investigation.  72:1410-1419. 1983
1983 THE IgA RESPONSE: INDUCTIVE ASPECTS, REGULATORY CELLS, AND EFFECTOR FUNCTIONSAnnals of the New York Academy of Sciences.  409:48-71. 1983
1982 In vitro regulation of IgA subclass synthesis: I. Discordance between plasma cell production and antibody secretionJournal of Experimental Medicine.  156:1615-1621. 1982
1982 Murine peyer’s patch T cell clones: Characterization of antigen-specific helper T cells for immunoglobulin a responsesJournal of Experimental Medicine.  156:1115-1130. 1982
1982 A quantitative assay for IgA rheumatoid factorJournal of Immunological Methods.  50:89-98. 1982
1982 Buffer electrofocusing of Interleukin I 1982
1982 An enzymatic method for preparation of dissociated murine Peyer's patch cells enriched for macrophagesJournal of Immunological Methods.  48:33-44. 1982
1982 Differential patterns of in vitro IgM rheumatoid factor synthesis in seronegative and seropositive rheumatoid arthritisArthritis and Rheumatism.  25:150-155. 1982
1982 Seronegative rheumatoid arthritis.Arthritis and Rheumatism.  25:502-507. 1982
1981 Lymphoid cell responses to bacterial cell wall components: Polyclonal and immune responses of murine B cells to Streptococcus mutans carbohydrate antigensJournal of Immunology.  127:2106-2112. 1981
1981 Interleukin 1: Production by P388D1 cells attached to microcarrier beadsJournal of Immunological Methods.  46:197-204. 1981
1981 Suppressor T Cells Prevent in Vitro Expression of IgM Rheumatoid Factor in Some Healthy Adults 1981
1980 Production of predominantly polymeric IgA by human peripheral blood lymphocytes stimulated in vitro with mitogensJournal of Experimental Medicine.  152:1424-1429. 1980
1980 A sensitive radioimmunoassay for quantitation of igm rheumatoid factorArthritis and Rheumatism.  23:302-308. 1980
1980 Dermal fibrosis in spinal cord injury patientsArthritis and Rheumatism.  23:1312-1317. 1980
1980 Enhanced in vitro synthesis of igm rheumatoid factor in rheumatoid arthritisArthritis and Rheumatism.  23:985-992. 1980
1980 In vitro synthesis of IgM rheumatoid factor by lymphocytes from healthy adultsJournal of Immunology.  125:934-938. 1980

Education And Training

  • Doctor of Medicine in Immunology, Harvard University 1972
  • Full Name

  • William Koopman