Positions

Selected Publications

Academic Article

Year Title Altmetric
2019 Towards Clinical Translation of CD8+ Regulatory T Cells Restricted by Non-Classical Major Histocompatibility Complex Ib MoleculesInternational Journal of Molecular Sciences.  20. 2019
2019 Current and future imaging methods for evaluating response to immunotherapy in neuro-oncologyTheranostics2019
2019 Metabolic and functional reprogramming of myeloid-derived suppressor cells and their therapeutic control in glioblastoma.Cell Stress.  3:47-65. 2019
2019 Deletion of the RNA regulator HuR in tumor-associated microglia and macrophages stimulates anti-tumor immunity and attenuates glioma growthGlia2019
2018 Chromatin remodeling by the NuRD complex regulates development of follicular helper and regulatory T cellsProceedings of the National Academy of Sciences.  115:6780-6785. 2018
2018 CD8+ T cells expressing both PD-1 and TIGIT but not CD226 are dysfunctional in acute myeloid leukemia (AML) patientsClinical Immunology.  190:64-73. 2018
2018 Lymphocytes contribute to the pathophysiology of neonatal brain injuryFrontiers in Neurology.  9. 2018
2018 γδ T Cells Contribute to Injury in the Developing BrainAmerican Journal of Pathology.  188:757-767. 2018
2018 Alphavirus Replicon DNA vectors expressing Ebola GP and VP40 antigens induce humoral and cellular immune responses in miceFrontiers in Microbiology.  8. 2018
2017 γδT cells but not αβT cells contribute to sepsis-induced white matter injury and motor abnormalities in miceJournal of Neuroinflammation.  14. 2017
2017 Newly Characterized Murine Undifferentiated Sarcoma Models Sensitive to Virotherapy with Oncolytic HSV-1 M002Molecular Therapy - Oncolytics.  7:27-36. 2017
2017 Modulation of the intratumoral immune landscape by oncolytic herpes simplex virus virotherapyFrontiers in Oncology.  7. 2017
2017 The Role of Microglia and Macrophages in CNS Homeostasis, Autoimmunity, and CancerJournal of Immunology Research.  2017. 2017
2015 Ezh2 regulates differentiation and function of natural killer cells through histone methyltransferase activityProceedings of the National Academy of Sciences.  112:15988-15993. 2015
2015 A p85α-osteopontin axis couples the receptor ICOS to sustained Bcl-6 expression by follicular helper and regulatory T cellsNature Immunology.  16:96-106. 2015
2015 NK cell-based cancer immunotherapy: from basic biology to clinical applicationScience China Life Sciences.  58:1233-1245. 2015
2015 Intracellular osteopontin regulates homeostasis and function of natural killer cellsProceedings of the National Academy of Sciences.  112:494-499. 2015
2014 The effect of osteopontin and osteopontin-derived peptides on preterm brain injuryJournal of Neuroinflammation.  11. 2014
2014 The immune response after hypoxia-ischemia in a mouse model of preterm brain injuryJournal of Neuroinflammation.  11. 2014
2013 Amelioration of arthritis through mobilization of peptide-specific CD8 + regulatory T cellsJournal of Clinical Investigation.  123:1382-1389. 2013
2011 Mobilization of natural killer cells inhibits development of collagen-induced arthritisProceedings of the National Academy of Sciences.  108:14584-14589. 2011
2010 Analysis of the cellular mechanism underlying inhibition of EAE after treatment with anti-NKG2A F(ab′)2Proceedings of the National Academy of Sciences.  107:2562-2567. 2010
2009 SUMO conjugation contributes to immune deviation in nonobese diabetic mice by suppressing c-Maf transactivation of IL-4Journal of Immunology.  183:1110-1119. 2009
2009 Engagement of transgenic Ly49A inhibits mouse CD4 cell activation by disrupting T cell receptor, but not CD28, signalingCellular Immunology.  257:88-96. 2009
2007 c-Maf interacts with c-Myb to down-regulate Bcl-2 expression and increase apoptosis in peripheral CD4 cellsEuropean Journal of Immunology.  37:2868-2880. 2007

Education And Training

  • Doctor of Philosophy in Molecular Biology, Southern Illinois University System : Edwardsville 2009
  • Doctor of Medicine, Nantong University 2001
  • Full Name

  • Jianmei Leavenworth