Positions

Overview

  • Dr. Tector is a liver transplant surgeon with clinical expertise in multi-visceral and small bowel transplantation. He is a funded surgeon-scientist with a nationally recognized research program in xenotransplantation. Dr. Tector is the director of the UAB Xenotransplant program.

    Dr. Tector received his undergraduate degree from Indiana University in 1987. He earned his doctorate at Saint Louis University in 1992 and completed his general surgery training at McGill University in Montreal, Canada in 1999. Dr. Tector completed his fellowship in Abdominal Transplant at the University of Miami in 2001. Dr. Tector earned his doctorate from McGill University in 2003.

    Prior to joining UAB, Dr. Tector was chief medical officer at the Indiana University Health Transplant Institute, chairman of the board of trustees at Indiana University, and medical director of organ transplantation. Dr. Tector was very involved in teaching the Research Organ Transplant, Transplant Immunology Lab at Indiana, which is a lab technique instruction course. He has worked with Riley transplant rotation Education of Pediatric GI Fellows in their Clinical Education and Conference, the Transplant Fellowship Program and adult Hepatology Fellows. He has also been an instructor of The Organ Trail: New Pathways in Transplantation at IUSM Mimi Medical School; Continuing Medical Education Course at the 7th Annual Gastroenterology/Hepatology Update: Gastroenterology in Practice.

    Tector has given 54 presentations in the United States and Canada, and he has 101 peer-reviewed articles and one book chapter.

    Tector is the associate editor of “Xenotransplantation Journal,” editorial board member of the “World Journal of Transplantation,” and “Xenotransplantation Journal.” He also is Ad Hoc Reviewer for the “Annals of Surgery,” “American Journal of Transplantation,” and the “British Journal of Surgery.”
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2018 Data on B cell phenotypes in baboons with pig artery patch grafts receiving conventional immunosuppressive therapyData in Brief.  20:1965-1974. 2018
    2018 Xenoantigen Deletion and Chemical Immunosuppression Can Prolong Renal Xenograft SurvivalAnnals of Surgery.  268:564-573. 2018
    2018 Crispr/Cas and recombinase-based human-to-pig orthotopic gene exchange for xenotransplantationJournal of Surgical Research.  229:28-40. 2018
    2018 Xenotransplantation panel for the detection of infectious agents in pigsXenotransplantation.  25. 2018
    2018 Examining the biosynthesis and xenoantigenicity of Class II swine leukocyte antigen proteinsJournal of Immunology.  200:2957-2964. 2018
    2018 Xenotransplantation - The current status and prospectsBritish Medical Bulletin.  125:5-14. 2018
    2018 Swine Leukocyte Antigen Class II Is a XenoantigenTransplantation.  102:249-254. 2018
    2017 The Resurgence of XenotransplantationAmerican Journal of Transplantation.  17:2531-2536. 2017
    2017 Efficient generation of targeted and controlled mutational events in porcine cells using nuclease-directed homologous recombinationJournal of Surgical Research.  212:238-245. 2017
    2017 A Novel Approach in Combined Liver and Kidney Transplantation with Long-term OutcomesAnnals of Surgery.  265:1000-1008. 2017
    2017 Humoral Reactivity of Renal Transplant-Waitlisted Patients to Cells from GGTA1/CMAH/B4GalNT2, and SLA Class i Knockout PigsTransplantation.  101:e86-e92. 2017
    2017 CRISPR genome-editing: A medical revolutionJournal of Thoracic and Cardiovascular Surgery.  153:488-491. 2017
    2016 Silencing porcine genes significantly reduces human-anti-pig cytotoxicity profiles: an alternative to direct complement regulationTransgenic Research.  25:751-759. 2016
    2016 The fate of human platelets exposed to porcine renal endothelium: a single-pass model of platelet uptake in domestic and genetically modified porcine organsJournal of Surgical Research.  200:698-706. 2016
    2015 Prognosis after recurrence of hepatocellular carcinoma in liver transplantation: Predictors for successful treatment and survivalClinical Transplantation.  29:1156-1163. 2015
    2014 Efficient generation of genetically distinct pigs in a single pregnancy using multiplexed single-guide RNA and carbohydrate selectionXenotransplantation2014
    2002 Hepatic sinusoidal endothelium upregulates IL-1α, IFN-γ, and iNOS in response to discordant xenogeneic islets in an in vitro model of xenoislet transplantationJournal of Surgical Research.  102:229-236. 2002
    2001 Rejection of pig liver xenografts in patients with liver failure: Implications for xenotransplantationLiver Transplantation and Surgery.  7:82-89. 2001
    2000 Experimental discordant hepatic xenotransplantation in the recipient with liver failure: Implications for clinical bridging trialsJournal of The American College of Surgeons.  191:54-64. 2000

    Chapter

    Year Title Altmetric
    2017 Clinical aspects of liver transplantation.  605-627. 2017

    Research Overview

  • Xenotransplantation
  • Education And Training

  • Doctor of Medicine, Saint Louis University 1992
  • McGill University School of Medicine, Residency 1999
  • University of Miami, Postdoctoral Fellowship 2001
  • Full Name

  • Joseph Tector