Disease Models and Mechanisms

Journal

Publication Venue For

  • Pharmacological or genetic inhibition of hypoxia signaling attenuates oncogenic RAS-induced cancer phenotypes.  15. 2021
  • Teleological role of L-2-hydroxyglutarate dehydrogenase in the kidney.  13. 2020
  • Modeling neurodegeneration in Caenorhabditis elegans.  13. 2020
  • A regulated NMD mouse model supports NMD inhibition as a viable therapeutic option to treat genetic diseases.  13. 2020
  • Mitochondrial damage and senescence phenotype of cells derived from a novel frataxin G127V point mutation mouse model of Friedreich's ataxia.  13. 2020
  • A regulated NMD mouse model supports NMD inhibition as a viable therapeutic option to treat genetic diseases. 2020
  • Mitochondrial damage and senescence phenotype of cells derived from a novel frataxin G127V point mutation mouse model of Friedreich's ataxia. 2020
  • Teleological Role of L-2-Hydroxyglutarate Dehydrogenase in the Kidney. 2020
  • ApoE-associated modulation of neuroprotection from Aβ-mediated neurodegeneration in transgenic Caenorhabditis elegans.  12. 2019
  • A small-molecule TrkB ligand restores hippocampal synaptic plasticity and object location memory in Rett syndrome mice.  10:837-845. 2017
  • A Drosophila model of dominant inclusion body myopathy type 3 shows diminished myosin kinetics that reduce muscle power and yield myofibrillar defects..  10:761-771. 2017
  • Increased trabecular bone and improved biomechanics in an osteocalcin-null rat model created by CRISPR/Cas9 technology.  9:1169-1179. 2016
  • Mice with missense and nonsense NF1 mutations display divergent phenotypes compared with human neurofibromatosis type I.  9:759-767. 2016
  • Variations in dysfunction of sister chromatid cohesion in esco2 mutant zebrafish reflect the phenotypic diversity of Roberts syndrome.  8:941-955. 2015
  • Treatment of cardiac arrhythmias in a mouse model of Rett syndrome with Na+-channel-blocking antiepileptic drugs.  8:363-371. 2015
  • TorsinA rescues ER-associated stress and locomotive defects in C. elegans models of ALS.  7:233-243. 2014
  • Preclinical research in Rett syndrome: Setting the foundation for translational success.  5:733-745. 2012
  • The ferret as a model organism to study influenza A virus infection.  4:575-579. 2011
  • Chemical enhancement of torsinA function in cell and animal models of torsion dystonia.  3:386-396. 2010
  • Target validation: The Parkinson disease perspective.  3:259-262. 2010
  • Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson's disease models.  3:194-208. 2010
  • Genetic modeling of Li-Fraumeni syndrome in zebrafish.  3:45-56. 2010
  • Traversing a wormhole to combat Parkinson's disease.  1:32-36. 2008
  • International Standard Serial Number (issn)

  • 1754-8403
  • Electronic International Standard Serial Number (eissn)

  • 1754-8411