JCI insight

Journal

Publication Venue For

  • Fluid-electrolyte homeostasis requires histone deacetylase function.  5. 2020
  • Lipid mediators and biomarkers associated with type 1 diabetes development.  5. 2020
  • Synchronization of mothers and offspring promotes tolerance and limits allergy.  5. 2020
  • The value of genotypic and imaging information to predict functional and structural outcomes in ADPKD.  5. 2020
  • Deep neural network analyses of spirometry for structural phenotyping of chronic obstructive pulmonary disease.  5. 2020
  • Longitudinal COVID-19 profiling associates IL-1RA and IL-10 with disease severity and RANTES with mild disease.  5. 2020
  • Selective LXR agonist DMHCA corrects retinal and bone marrow dysfunction in type 2 diabetes.  5. 2020
  • Brd4-p300 inhibition downregulates Nox4 and accelerates lung fibrosis resolution in aged mice.  5. 2020
  • Free light chains injure proximal tubule cells through the STAT1/HMGB1/TLR axis.  5. 2020
  • Myocardial protection by nanomaterials formulated with CHIR99021 and FGF1.  5. 2020
  • Th17 reprogramming of T cells in systemic juvenile idiopathic arthritis.  5. 2020
  • Monocyte-derived alveolar macrophage apolipoprotein E participates in pulmonary fibrosis resolution.  5. 2020
  • Association of urine mitochondrial DNA with clinical measures of COPD in the SPIROMICS cohort.  5. 2020
  • LXRs regulate features of age-related macular degeneration and may be a potential therapeutic target.  5. 2020
  • Neutrophil-Targeted, protease-Activated pulmonary drug delivery blocks airway and systemic inflammation.  4. 2019
  • IL-1RA regulates immunopathogenesis during fungal-Associated allergic airway inflammation.  4. 2019
  • Progenitor cell combination normalizes retinal vascular development in the oxygen-induced retinopathy (OIR) model.  4. 2019
  • Cadherin-11 blockade reduces inflammation-driven fibrotic remodeling and improves outcomes after myocardial infarction.  4. 2019
  • NOX4 modulates macrophage phenotype and mitochondrial biogenesis in asbestosis.  4. 2019
  • Therapeutic suppression of pulmonary neutrophilia and allergic airway hyperresponsiveness by an RORĪ³t inverse agonist.  4. 2019
  • Soluble membrane attack complex is diagnostic for intraventricular shunt infection in children.  1. 2019
  • Vimentin intermediate filament assembly regulates fibroblast invasion in fibrogenic lung injury.  4. 2019
  • Long noncoding RNA Malat1 regulates differential activation of macrophages and response to lung injury.  4. 2019
  • Resident macrophages reprogram toward a developmental state after acute kidney injury.  4. 2019
  • SIRT3 diminishes inflammation and mitigates endotoxin-induced acute lung injury.  4. 2019
  • A glycopolymer improves vascoelasticity and mucociliary transport of abnormal cystic fibrosis mucus.  4. 2019
  • Deficiency of Socs3 leads to brain-targeted experimental autoimmune encephalomyelitis via enhanced neutrophil activation and ROS production.  4. 2019
  • Racial differences in the association of NT-proBNP with risk of incident heart failure in REGARDS.  4. 2019
  • Effect of ivacaftor on mucociliary clearance and clinical outcomes in cystic fibrosis patients with G551D-CFTR.  3. 2018
  • Matrix metalloproteinase-9 deficiency protects mice from severe influenza A viral infection.  3. 2018
  • Tumor-specific MHC-II expression drives a unique pattern of resistance to immunotherapy via LAG-3/FCRL6 engagement.  3. 2018
  • Elevated circulating MMP-9 is linked to increased COPD exacerbation risk in SPIROMICS and COPDGene.  3. 2018
  • Heme scavenging reduces pulmonary endoplasmic reticulum stress, fibrosis, and emphysema.  3. 2018
  • Influenza-mediated reduction of lung epithelial ion channel activity leads to dysregulated pulmonary fluid homeostasis.  3. 2018
  • Myeloid HO-1 modulates macrophage polarization and protects against ischemia-reperfusion injury.  3. 2018
  • A limb-girdle muscular dystrophy 2I model of muscular dystrophy identifies corrective drug compounds for dystroglycanopathies.  3. 2018
  • Exosomal microRNA predicts and protects against severe bronchopulmonary dysplasia in extremely premature infants.  3. 2018
  • Cell-free hemoglobin promotes primary graft dysfunction through oxidative lung endothelial injury.  3. 2018
  • Development of an airway mucus defect in the cystic fibrosis rat.  3. 2018
  • Addition of carbonic anhydrase 9 inhibitor SLC-0111 to temozolomide treatment delays glioblastoma growth in vivo..  2. 2017
  • Angiotensin-converting enzyme defines matrikine-regulated inflammation and fibrosis.  2. 2017
  • Nasospheroids permit measurements of CFTR-dependent fluid transport.  2. 2017
  • Dietary potassium regulates vascular calcification and arterial stiffness..  2. 2017
  • Irgm1 coordinately regulates autoimmunity and host defense at select mucosal surfaces.  2. 2017
  • Sustained immune tolerance induction in enzyme replacement therapy-treated CRIM-negative patients with infantile Pompe disease.  2. 2017
  • Host interleukin 6 production regulates inflammation but not tryptophan metabolism in the brain during murine GVHD.  2. 2017
  • Preexisting antibodies can protect against congenital cytomegalovirus infection in monkeys.  2. 2017
  • 3D pulmospheres serve as a personalized and predictive multicellular model for assessment of antifibrotic drugs.  2. 2017
  • Assessment of ciliary phenotype in primary ciliary dyskinesia by micro-optical coherence tomography..  2:e91702. 2017
  • Mitophagy and mitochondrial biogenesis in atrial tissue of patients undergoing heart surgery with cardiopulmonary bypass..  2:e89303. 2017
  • 3D pulmospheres serve as a personalized and predictive multicellular model for assessment of antifibrotic drugs..  2:e91377. 2017
  • A ferret model of COPD-related chronic bronchitis.  1:e87536. 2016
  • Analysis of cystic fibrosis-associated P67L CFTR illustrates barriers to personalized therapeutics for orphan diseases..  1. 2016
  • Hybrid inhibitor of peripheral cannabinoid-1 receptors and inducible nitric oxide synthase mitigates liver fibrosis..  1. 2016
  • Heme oxygenase-1 regulates mitochondrial quality control in the heart..  1:e85817. 2016
  • International Standard Serial Number (issn)

  • 2379-3708
  • Electronic International Standard Serial Number (eissn)

  • 2379-3708