Molecular and Cellular Biology

Regional gene repression by DNA double-strand breaks in G1 phase cells.  39. 2019

MUNC, an enhancer RNA upstream from the MYOD gene, induces a subgroup of myogenic transcripts in trans independently of MyoD.  38. 2018

Modulation of heat shock factor 1 activity through silencing of Ser303/Ser307 phosphorylation supports a metabolic program leading to age-related obesity and insulin resistance.  38. 2018

Corrected and republished from: BCL11A is a critical component of a transcriptional network that activates RAG expression and V(D)J recombination.  38. 2018

Retraction: "The BCL11A transcription factor directly activates RAG gene expression and V(D)J recombination." [Molecular and Cellular Biology, 33, 9, (2013), (1768-1781)] doi: 10.1128/MCB.00987-12.  37. 2017

E2F-2 promotes nuclear condensation and enucleation of terminally differentiated erythroblasts.  37. 2017

Interactome analysis reveals a novel role for RAD6 in the regulation of proteasome activity and localization in response to DNA damage.  37. 2017

Endothelial mitogen-activated protein kinase kinase kinase kinase 4 is critical for lymphatic vascular development and function.  36:1740-1749. 2016

GGA3 interacts with a G protein-coupled receptor and modulates its cell surface export.  36:1152-1163. 2016

Novel microRNA regulators of atrial natriuretic peptide production.  36:1977-1987. 2016

Enhanced cardiac Akt/protein kinase B signaling contributes to pathological cardiac hypertrophy in part by impairing mitochondrial function via transcriptional repression of mitochondrion-targeted nuclear genes.  35:831-846. 2015

MUNC, a long noncoding RNA that facilitates the function of MyoD in skeletal myogenesis.  35:498-513. 2015

MicroRNA 665 regulates dentinogenesis through microRNA-mediated silencing and epigenetic mechanisms.  35:3116-3130. 2015

Spt6 is essential for rRNA synthesis by RNA polymerase I.  35:2321-2331. 2015

14-3-3 proteins play a role in the cell cycle by shielding Cdt2 from ubiquitin-mediated degradation.  34:4049-4061. 2014

Insulin receptor substrates are essential for the bioenergetic and hypertrophic response of the heart to exercise training.  34:3450-3460. 2014

KAP-1 promotes resection of broken DNA ends not protected by γ-H2AX and 53BP1 in G1-phase lymphocytes.  34:2811-2821. 2014

PEA15 regulates the DNA damage-induced cell cycle checkpoint and oncogene-directed transformation.  34:2264-2282. 2014

Perk-dependent activation of JAK1 and STAT3 contributes to endoplasmic reticulum stress-induced inflammation.  34:3911-3925. 2014

Functional intersection of ATM and DNA-dependent protein kinase catalytic subunit in coding end joining during V(D)J recombination.  33:3568-3579. 2013

Parkin-Dependent Degradation of the F-Box Protein Fbw7β Promotes Neuronal Survival in Response to Oxidative Stress by Stabilizing Mcl-1.  33:3627-3643. 2013

Deubiquitination of tip60 by USP7 determines the activity of the p53-dependent apoptotic pathway.  33:3309-3320. 2013

Erythropoiesis in the absence of adult hemoglobin.  33:2241-2251. 2013

Men1 is a melanoma tumor suppressor that preserves genomic integrity by stimulating transcription of genes that promote homologous recombination-directed dna repair.  33:2635-2647. 2013

Abstract 4604: Landscape of human and viral genomic alterations in cervical carcinomas. 2013

The MCM8-MCM9 complex Promotes RAD51 recruitment at DNA damage sites to facilitate homologous recombination.  33:1632-1644. 2013

Trip6 regulates p27^KIP1 to promote tumorigenesis.  33:1394-1409. 2013

RVBs are required for assembling a functional TIP60 complex.  33:1163-1174. 2013

Ribosomal protein S25 dependency reveals a common mechanism for diverse internal ribosome entry sites and ribosome shunting.  33:1016-1026. 2013

TAK1 is essential for osteoclast differentiation and is an important modulator of cell death by apoptosis and necroptosis.  33:582-595. 2013

The bcl11a transcription factor directly activates RAG gene expression and V(D)J recombination.  33:1768-1781. 2013

The hypersensitive glucocorticoid response specifically regulates period 1 and expression of circadian genes.  32:3756-3767. 2012

C-src links a RANK/αvβ3 integrin complex to the osteoclast cytoskeleton.  32:2943-2953. 2012

Telomerase Recruitment Requires both TCAB1 and Cajal Bodies Independently.  32:2384-2395. 2012

Myocardial ATGL overexpression decreases the reliance on fatty acid oxidation and protects against pressure overload-induced cardiac dysfunction.  32:740-750. 2012

IRE1-dependent activation of AMPK in response to nitric oxide.  31:4286-4297. 2011

Selective ubiquitylation of p21 and Cdt1 by UBCH8 and UBE2G ubiquitin-conjugating enzymes via the CRL4 ^Cdt2 ubiquitin ligase complex.  31:3136-3145. 2011

Chromosome-wide analysis of parental allele-specific chromatin and DNA methylation.  31:1757-1770. 2011

miR-206 and -486 induce myoblast differentiation by downregulating Pax7 (Molecular and Cellular Biology (2010) 31, 1, (203-214)).  31:1329. 2011

Human globin knock-in mice complete fetal-to-adult hemoglobin switching in postnatal development.  31:876-883. 2011

miR-206 and -486 induce myoblast differentiation by downregulating Pax7.  31:203-214. 2011

The adaptor protein TRIP6 antagonizes fas-induced apoptosis but promotes its effect on cell migration.  30:5582-5596. 2010

Islet β-cell-specific MafA transcription requires the 5′-Flanking conserved region 3 control domain.  30:4234-4244. 2010

Pbx1 represses osteoblastogenesis by blocking Hoxa10-mediated recruitment of chromatin remodeling factors.  30:3531-3541. 2010

Allele-specific H3K79 di- versus trimethylation distinguishes opposite parental alleles at imprinted regions.  30:2693-2707. 2010

Transcription factor glis3, a novel critical player in the regulation of pancreatic β-cell development and insulin gene expression (Molecular and Cellular Biology (2009) 29, 24, (6366-6379)).  30:1964. 2010

Pirh2 E3 ubiquitin ligase targets DNA polymerase eta for 20S proteasomal degradation.  30:1041-1048. 2010

Transcription factor glis3, a novel critical player in the regulation of pancreatic β-cell development and insulin gene expression.  29:6366-6379. 2009

Fumarate hydratase deficiency in renal cancer induces glycolytic addiction and hypoxia-inducible transcription factor 1α stabilization by glucose-dependent generation of reactive oxygen species.  29:4080-4090. 2009

Glis3 is associated with primary cilia and Wwtr1/TAZ and implicated in polycystic kidney disease.  29:2556-2569. 2009

Regulation of p53 by TopBP1: A potential mechanism for p53 inactivation in cancer.  29:2673-2693. 2009

Laforin negatively regulates cell cycle progression through glycogen synthase kinase 3β-dependent mechanisms.  28:7236-7244. 2008

The ING4 tumor suppressor attenuates NF-κB activity at the promoters of target genes.  28:6632-6645. 2008

Visual analysis of the yeast 5S rRNA gene transcriptome: Regulation and role of La protein.  28:4576-4587. 2008

Human Rvb1/Tip49 is required for the histone acetyltransferase activity of Tip60/NuA4 and for the downregulation of phosphorylation on H2AX after DNA damage.  28:2690-2700. 2008

Krüppel-like zinc finger protein Glis2 is essential for the maintenance of normal renal functions.  28:2358-2367. 2008

Role of hPHF1 in H3K27 methylation and Hox gene silencing.  28:1862-1872. 2008

CHD8 associates with human staf and contributes to efficient U6 RNA polymerase III transcription.  27:8729-8738. 2007

Protein kinase A, Ca²⁺/calmodulin-dependent kinase II, and calcineurin regulate the intracellular trafficking of myopodin between the Z-disc and the nucleus of cardiac myocytes.  27:8215-8227. 2007

T-bet's ability to regulate individual target genes requires the conserved T-box domain to recruit histone methyltransferase activity and a separate family member-specific transactivation domain.  27:8510-8521. 2007

UBE2T, the Fanconi anemia core complex, and FANCD2 are recruited independently to chromatin: A basis for the regulation of FANCD2 monoubiquitination.  27:8421-8430. 2007

TOR signaling is a determinant of cell survival in response to DNA damage.  27:7007-7017. 2007

ASB4 is a hydroxylation substrate of FIH and promotes vascular differentiation via an oxygen-dependent mechanism.  27:6407-6419. 2007

Erbin inhibits transforming growth factor β signaling through a novel Smad-interacting domain.  27:6183-6194. 2007

Erratum: Role of the Orc6 protein in origin recognition complex-dependent DNA binding and replication in Drosophila melanogaster (Molecular and Cellular Biology (2007) 27,8, (3143-3153)).  27:4206. 2007

HOXA10 controls osteoblastogenesis by directly activating bone regulatory and phenotypic genes.  27:3337-3352. 2007

Role of the Orc6 protein in origin recognition complex-dependent DNA binding and replication in Drosophila melanogaster.  27:3143-3153. 2007

O-GlcNAc integrates the proteasome and transcriptome to regulate nuclear hormone receptors.  26:8539-8550. 2006

Distinct functional domains of Ubc9 dictate cell survival and resistance to genotoxic stress.  26:4958-4969. 2006

Tpa1p is part of an mRNP complex that influences translation termination, mRNA deadenylation, and mRNA turnover in Saccharomyces cerevisiae.  26:5237-5248. 2006

Alterations in expression and chromatin configuration of the alpha hemoglobin-stabilizing protein gene in erythroid Krüppel-like factor-deficient mice.  26:4368-4377. 2006

An ATR- and BRCA1-mediated fanconi anemia pathway is required for activating the G2/M checkpoint and DNA damage repair upon rereplication.  26:4601-4611. 2006

Tethering KSRP, a decay-promoting AU-rich element-binding protein, to mRNAs elicits mRNA decay.  26:3695-3706. 2006

Proteasome activator PA200 is required for normal spermatogenesis.  26:2999-3007. 2006

Myosin VI is a mediator of the p53-dependent cell survival pathway.  26:2175-2186. 2006

DNA polymerase η, the product of the xeroderma pigmentosum variant gene and a target of p53, modulates the DNA damage checkpoint and p53 activation.  26:1398-1413. 2006

Distinct paths to stop codon reassignment by the variant-code organisms Tetrahymena and Euplotes.  26:438-447. 2006

Tissue-specific differences of p53 inhibition by Mdm2 and Mdm4.  26:192-198. 2006

PGC-1α coactivates PDK4 gene expression via the orphan nuclear receptor ERRα: A mechanism for transcriptional control of muscle glucose metabolism.  25:10684-10694. 2005

Loss of Smad3-mediated negative regulation of Runx2 activity leads to an alteration in cell fate determination.  25:9460-9468. 2005

The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion.  25:8581-8591. 2005

Reduced genomic cytosine methylation and defective cellular differentiation in embryonic stem cells lacking CpG binding protein.  25:4881-4891. 2005

Jumonji represses atrial natriuretic factor gene expression by inhibiting transcriptional activities of cardiac transcription factors.  24:10151-10160. 2004

Dlx3 transcriptional regulation of osteoblast differentiation: Temporal recruitment of Msx2, Dlx3, and Dlx5 homeodomain proteins to chromatin of the osteocalcin gene.  24:9248-9261. 2004

Identification of cyclin D3 as a direct target of E2A using DamID.  24:8790-8802. 2004

GTP hydrolysis by eRF3 facilitates stop codon decoding during eukaryotic translation termination.  24:7769-7778. 2004

Sequestosome 1/p62 is a polyubiquitin chain binding protein involved in ubiquitin proteasome degradation.  24:8055-8068. 2004

Rereplication by depletion of geminin is seen regardless of p53 status and activates a G2/M checkpoint.  24:7140-7150. 2004

Coordination of cell signaling, chromatin remodeling, histone modifications, and regulator recruitment in human matrix metalloproteinase 9 gene transcription.  24:5496-5509. 2004

The NAD(P)H Oxidase Homolog Nox4 Modulates Insulin-Stimulated Generation of H2O2 and Plays an Integral Role in Insulin Signal Transduction.  24:1844-1854. 2004

Nicotinamide Clearance by Pnc1 Directly Regulates Sir2-Mediated Silencing and Longevity.  24:1301-1312. 2004

DeltaNp73beta is active in transactivation and growth suppression..  24:487-501. 2004

ΔNp73β Is Active in Transactivation and Growth Suppression.  24:487-501. 2004

Activated Notch2 Potentiates CD8 Lineage Maturation and Promotes the Selective Development of B1 B Cells.  23:8637-8650. 2003

EBNA-1, a bifunctional transcriptional activator.  23:6901-6908. 2003

Erratum: Delineation of a novel pathway that regulates CD154 (CD40 ligand) expression (Molecular and Cellular Biology (2003) 23:2 (510-525)).  23:6338. 2003

Support for a meiotic recombination initiation complex: Interactions among Rec102p, Rec104p, and Spo11p.  23:5928-5938. 2003

Regulation of the bone-specific osteocalcin gene by p300 requires Runx2/Cbfa1 and the vitamin D3 receptor but not p300 intrinsic histone acetyltransferase activity.  23:3339-3351. 2003

CFTR Mediates RANTES Expression In Airway Epithelia Via Participation In A Macromolecular Signaling Complex At the Membrane Surface.  23:549-606. 2003

Delineation of a novel pathway that regulates CD154 (CD40 ligand) expression.  23:510-525. 2003

Plasma membrane CFTR regulates RANTES expression via its C-terminal PDZ-interacting motif.  23:594-606. 2003

Identification of mZnf8, a mouse Krüppel-like transcriptional repressor, as a novel nuclear interaction partner of Smad1.  22:7633-7644. 2002

Chaperone proteins abrogate inhibition of the human papillomavirus (HPV) E1 replicative helicase by the HPV E2 protein.  22:6592-6604. 2002

Hematopoietic stem cell expansion and distinct myeloid developmental abnormalities in a murine model of the AML1-ETO translocation.  22:5506-5517. 2002

Tumor necrosis factor-related apoptosis-inducing ligand induces caspase-dependent interleukin-8 expression and apoptosis in human astroglioma cells.  22:724-736. 2002

Promotion of cell cycle progression by basic helix-loop-helix E2A.  21:6346-6357. 2001

Overproduction of PDR3 suppresses mitochondrial import defects associated with a TOM70 null mutation by increasing the expression of TOM72 in saccharomyces cerevisiae.  21:7576-7586. 2001

Use of chromatin immunoprecipitation to clone novel E2F target promoters.  21:6820-6832. 2001

Mutational analysis of the Cy motif from p21 reveals sequence degeneracy and specificity for different cyclin-dependent kinases.  21:4868-4874. 2001

Requirement of CDC45 for postimplantation mouse development.  21:4598-4603. 2001

Runt homology domain transcription factors (Runx, Cbfa, and AML) mediate repression of the bone sialoprotein promoter: Evidence for promoter context-dependent activity of Cbfa proteins.  21:2891-2905. 2001

Recruitment of an RNA polymerase II complex is mediated by the constitutive activation domain in CREB, independently of CREB phosphorylation.  21:1001-1010. 2001

Cloning and functional characterization of the early-lymphocyte-specific Pb99 gene.  20:4405-4410. 2000

STRAP and Smad7 synergize in the inhibition of transforming growth factor β signaling.  20:3157-3167. 2000

Rapid deadenylation and Poly(A)-dependent translational repression mediated by the Caenorhabditis elegans tra-2 3' untranslated region in Xenopus embryos.  20:2129-2137. 2000

The Rous sarcoma virus Env glycoprotein contains a highly conserved motif homologous to tyrosine-based endocytosis signals and displays an unusual internalization phenotype.  20:249-260. 2000

Identification of a gene that reverses the immortal phenotype of a subset of cells and is a member of a novel family of transcription factor- like genes.  19:1479-1485. 1999

Multiple Cbfa/AML sites in the rat osteocalcin promoter are required for basal and vitamin D-responsive transcription and contribute to chromatin organization.  19:7491-7500. 1999

Targeted disruption of Smad3 reveals an essential role in transforming growth factor β-mediated signal transduction.  19:2495-2504. 1999

Human CDC6/Cdc18 associates with Orc1 and cyclin-cdk and is selectively eliminated from the nucleus at the onset of S phase.  18:2758-2767. 1998

Recruitment and phosphorylation of SH2-containing inositol phosphatase and Shc to the B-cell Fcγ immunoreceptor tyrosine-based inhibition motif peptide motif.  17:4305-4311. 1997

The amino terminus of the F1-ATPase β-subunit precursor functions as an intramolecular chaperone to facilitate mitochondrial protein import.  17:7169-7177. 1997

p21(CIP1) and Cdc25A: Competition between an inhibitor and an activator of cyclin-dependent kinases.  17:4338-4345. 1997

3pK, a new mitogen-activated protein kinase-activated protein kinase located in the small cell lung cancer tumor suppressor gene region.  16:868-876. 1996

Cyclin-binding motifs are essential for the function of p21(CIP1).  16:4673-4682. 1996

Two distinct regions in the 3' untranslated region of tumor necrosis factor alpha mRNA form complexes with macrophage proteins.  16:5579-5590. 1996

p53 inhibits RNA polymerase III-directed transcription in a promoter- dependent manner.  16:7084-7088. 1996

A novel cis-acting element required for lipopolysaccharide-induced transcription of the murine interleukin-1β gene.  15:112-119. 1995

Association of p107 with Sp1: Genetically separable regions of p107 are involved in regulation of E2F- and Sp1-dependent transcription.  15:5444-5452. 1995

Rpa4, a homolog of the 34-kilodalton subunit of the replication protein A complex.  15:3119-3128. 1995

p53 stimulates transcription from the human transforming growth factor α promoter: A potential growth-stimulatory role for p53.  15:4694-4701. 1995

A critical role for chromatin in mounting a synergistic transcriptional response to GAL4-VP16.  14:5175-5181. 1994

Effect of CD28 signal transduction on c-Rel in human peripheral blood T cells.  14:7933-7942. 1994

Hel-N1: an autoimmune RNA-binding protein with specificity for 3' uridylate-rich untranslated regions of growth factor mRNAs.  13:3494-3504. 1993

Hel-N1: an autoimmune RNA-binding protein with specificity for 3' uridylate-rich untranslated regions of growth factor mRNAs..  13:3494-3504. 1993

NAB2: a yeast nuclear polyadenylated RNA-binding protein essential for cell viability..  13:2730-2741. 1993

A common element involved in transcriptional regulation of two DNA alkylation repair genes (MAG and MGT1) of Saccharomyces cerevisiae.  13:7213-7221. 1993

Discrimination among potential activators of the β-globin CACCC element by correlation of binding and transcriptional properties.  13:44-56. 1993

Identification and characterization of a β-globin promoter-binding factor from murine erythroleukemia cells.  13:4311-4322. 1993

Interleukin-5 (IL-5) and IL-6 define two molecularly distinct pathways of B-cell differentiation.  13:3929-3936. 1993

Properties of initiator-associated transcription mediated by GAL4-VP16.  13:7469-7475. 1993

5-Azacytidine treatment of HA-A melanoma cells induces Sp1 activity and concomitant transforming growth factor α expression.  12:3998-4006. 1992

BLyF, a novel cell-type- and stage-specific regulator of the B-lymphocyte gene mb-1.  12:1126-1133. 1992

CD8+ T-cell clones deficient in the expression of the CD45 protein tyrosine phosphatase have impaired responses to T-cell receptor stimuli..  11:4415-4422. 1991

CD8⁺ T-cell clones deficient in the expression of the CD45 protein tyrosine phosphatase have impaired responses to T-cell receptor stimuli.  11:4415-4422. 1991

Nonhomologous recombination at sites within the mouse J(H)-C(δ) locus accompanies Cμ deletion and switch to immunoglobulin D secretion.  11:5660-5670. 1991

Overexpression of transforming growth factor-β in transgenic mice carrying the human T-cell lymphotropic virus type I tax gene.  11:5222-5228. 1991

Phorbol esters selectively and reversibly inhibit a subset of myofibrillar genes responsible for the ongoing differentiation program of chick skeletal myotubes.  11:4473-4482. 1991

Significance of C-terminal cysteine modifications to the biological activity of the Saccharomyces cerevisiae a-factor mating pheromone.  11:3603-3612. 1991

A directly repeated sequence in the β-globin promoter regulates transcription in murine erythroleukemia cells.  10:972-981. 1990

Structure and variability of human chromosome ends.  10:518-527. 1990

Transforming growth factor α in arterioles: Cell surface processing of its precursor by elastases.  10:4596-4602. 1990

Regulation of type I (epidermal) transglutaminase mRNA levels during squamous differentiation: down regulation by retinoids.  9:4846-4851. 1989

Sequence and structural requirements of a mitochondrial protein import signal defined by saturation cassette mutagenesis.  9:1014-1025. 1989

DNA sequences involved in transcriptional regulation of the mouse β-globin promoter in murine erythroleukemia cells.  8:3122-3128. 1988

Modulation of microfilament protein composition by transfected cytoskeletal actin genes.  8:1790-1794. 1988

Structure, chromosome location, and expression of the human γ-actin gene: Differential evolution, location, and expression of the cytoskeletal β- and γ-actin genes.  8:1775-1789. 1988

The C proteins of heterogeneous nuclear ribonucleoprotein complexes interact with RNA sequences downstream of polyadenylation cleavage sites.  8:4477-4483. 1988

Synthesis of U1 RNA in isolated mouse cell nuclei: initiation and 3'-end formation.  7:4290-4296. 1987

Molecular cloning of gene sequences regulated during squamous differentiation of tracheal epithelial cells and controlled by retinoic acid.  7:4017-4023. 1987

The yeast F1-ATPase beta subunit precursor contains functionally redundant mitochondrial protein import information..  7:4038-4047. 1987

Differential response to retinoic acid of Syrian hamster embryo fibroblasts expressing v-src or v-Ha-ras oncogenes..  6:3341-3348. 1986