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Erythrocyte and plasma oxidative stress appears to be compensated in patients with sickle cell disease during a period of relative health, despite the presence of known oxidative agents.
Plasma xanthine oxidase activity is related to increased sodium and left ventricular hypertrophy in resistant hypertension.
The proinflammatory effects of macrophage-derived NADPH oxidase function in autoimmune diabetes.
Increased TFAM binding to mtDNA damage hot spots is associated with mtDNA loss in aged rat heart.
Rust never sleeps: The continuing story of the Iron Bolt.
An overview of the emerging interface between cardiac metabolism, redox biology and the circadian clock.
Circadian regulation of renal function.
Introduction to special issue: Circadian regulation of metabolism, redox signaling and function in health and disease.
Nrf2 in keratinocytes modulates UVB-induced DNA damage and apoptosis in melanocytes through MAPK signaling.
Hyper-activation of pp60Src limits nitric oxide signaling by increasing asymmetric dimethylarginine levels during acute lung injury.
TRPV4 activation of endothelial nitric oxide synthase resists nonalcoholic fatty liver disease by blocking CYP2E1-mediated redox toxicity.
Redox biology and the interface between bioenergetics, autophagy and circadian control of metabolism.
Redox regulation of epidermal growth factor receptor signaling during the development of pulmonary hypertension..
Modification of platelet proteins by 4-hydroxynonenal: Potential Mechanisms for inhibition of aggregation and metabolism.
Hydrogen Sulfide Alters M. Tuberculosis Bioenergetics and Promotes Tuberculosis Disease.
Targeting the isoprenoid pathway to abrogate progression of pulmonary fibrosis.
Red blood cell washing, nitrite therapy, and antiheme therapies prevent stored red blood cell toxicity after trauma-hemorrhage.
Upregulation of autophagy decreases chlorine-induced mitochondrial injury and lung inflammation.
Epigenetic mechanisms regulate NADPH oxidase-4 expression in cellular senescence.
Thioredoxin rod-derived cone viability factor protects against photooxidative retinal damage.
Exposure to Cigarette Smoke Causes DNA Damage and Contributes to Drug Resistance in Mycobacterium Tuberculosis.
A mitochondria-targeted mass spectrometry probe to detect glyoxals: Implications for diabetes.
Endothelin-1 stimulates catalase activity through the PKCδ-mediated phosphorylation of serine 167..
Redox regulation of antioxidants, autophagy, and the response to stress: Implications for electrophile therapeutics.
Mechanistic Insights into the Role of Hydrogen Sulfide in Mycobacterial Disease and Persistence.
Cyclooxygenase-2 in newborn hyperoxic lung injury.
Erratum: Elevated levels of NO are localized to distal airways in asthma (Free Radical Biology and Medicine (2011) 50 (1679-1688)).
Dietary patterns are associated with plasma F2-isoprostanes in an observational cohort study of adults.
Antioxidant functions for the hemoglobin β93 cysteine residue in erythrocytes and in the vascular compartment in vivo.
Temporal patterns of tyrosine nitration in embryo heart development.
Cellular metabolic and autophagic pathways: Traffic control by redox signaling.
Inhibition of autophagy and glycolysis by nitric oxide during hypoxia-reoxygenation impairs cellular bioenergetics and promotes cell death in primary neurons.
Mitochondrial genetics and obesity: Evolutionary adaptation and contemporary disease susceptibility.
Utilization of fluorescent probes for the quantification and identification of subcellular proteomes and biological processes regulated by lipid peroxidation products.
Vascular peroxidase 1 catalyzes the formation of hypohalous acids: Characterization of its substrate specificity and enzymatic properties.
Administration of nitrite after chlorine gas exposure prevents lung injury: Effect of administration modality.
Transforming growth factor β suppresses glutamate-cysteine ligase gene expression and induces oxidative stress in a lung fibrosis model.
Dysregulated TLR3-dependent signaling and innate immune activation in superoxide-deficient macrophages from nonobese diabetic mice.
Corrigendum to "Ozone exposure is a risk factor for Alzheimer's disease" [Free Radical Biology and Medicine (2011) 51 (S68)).
Metabolic syndrome and mitochondrial dysfunction: Insights from preclinical studies with a mitochondrially targeted antioxidant.
Measuring reactive oxygen and nitrogen species with fluorescent probes: Challenges and limitations.
Simvastatin impairs ADP-stimulated respiration and increases mitochondrial oxidative stress in primary human skeletal myotubes.
Differentiation of SH-SY5Y cells to a neuronal phenotype changes cellular bioenergetics and the response to oxidative stress.
Novel insights into interactions between mitochondria and xanthine oxidase in acute cardiac volume overload.
Assessing bioenergetic function in response to oxidative stress by metabolic profiling.
Reactive Oxygen Species and the Macroalgal Wound Response.
Role of VPO1, a newly identified heme-containing peroxidase, in ox-LDL induced endothelial cell apoptosis.
Oxidases and peroxidases in cardiovascular and lung disease: New concepts in reactive oxygen species signaling.
Vascular peroxidase-1 is rapidly secreted, circulates in plasma, and supports dityrosine cross-linking reactions.
Current perspectives and challenges in understanding the role of nitrite as an integral player in nitric oxide biology and therapy.
Generation and characterization of a novel kidney-specific manganese superoxide dismutase knockout mouse.
Elevated levels of NO are localized to distal airways in asthma.
Dipyridamole reverses peripheral ischemia and induces angiogenesis in the Db/Db diabetic mouse hind-limb model by decreasing oxidative stress.
Role of mitochondrial-derived oxidants in renal tubular cell cold-storage injury.
Thioredoxin-interacting protein inhibits hypoxia-inducible factor transcriptional activity.
ICAM-1 cytoplasmic tail regulates endothelial glutathione synthesis through a NOX4/PI3-kinase-dependent pathway.
Dietary flavonoid quercetin stimulates vasorelaxation in aortic vessels.
Mitochondrial dysfunction may explain the cardiomyopathy of chronic iron overload.
Mitochondrial reserve capacity in endothelial cells: The impact of nitric oxide and reactive oxygen species.
Effects of T-state and R-state stabilization on Deoxyhemoglobin-nitrite Reactions and Stimulation of Nitric Oxide (NO) Signaling.
Oxidative stress and glutathione in TGF-β-mediated fibrogenesis.
Post–Cl2 Exposure Therapeutics Using Nitrite: Different Effects of IM vs. IP Administration.
Role of Hemoglobin Beta93Cys as an Antioxidant in the Vascular Compartment: Implications for Vascular Homeostasis During Endotoxemia.
The Effects of Red Blood Cell Storage Time on Nitric Oxide and Nitrite-dependent Signaling.
The Role of Reactive Oxygen Species in Antiherbivore Defense along the Western Antarctic Peninsula.
Fibroblasts from long-lived mutant mice show diminished ERK1/2 phosphorylation but exaggerated induction of immediate early genes.
Long-term neuroprotection from a potent redox-modulating metalloporphyrin in the rat.
Methods for the determination and quantification of the reactive thiol proteome.
Methods for imaging and detecting modification of proteins by reactive lipid species.
Ozone Induces Pulmonary Fibrosis via a TGF-beta Signaling Pathway.
Ethanol and tobacco smoke increase hepatic steatosis and hypoxia in the hypercholesterolemic apoE-/- mouse: Implications for a "multihit" hypothesis of fatty liver disease.
Fatty acid transduction of nitric oxide signaling: nitrolinoleic acid mediates protective effects through regulation of the ERK pathway.
Supression of hemin-mediated oxidation of low-density lipoprotein and subsequent endothelial reactions by hydrogen sulfide (H2S).
Antioxidant Role of Hemoglobin Beta93 Cysteine in the Red Blood Cell and the Vascular Compartment.
Hypoxic Nitrite Reduction to Nitric Oxide Varies by Cell Type.
Mouse Strains with Differential Cardiovascular Disease Susceptibilities Have Significantly Different Measures of Mitochondrial Function and Damage.
Sodium Nitrite Administration Mitigates Lung Injury After Chlorine Gas Exposure in Rats.
Identification and characterization of VPO1, a new animal heme-containing peroxidase.
Redox modulation inhibits CD8 T cell effector function.
Redox modulation inhibits CD8 T cell effector function
Mitochondrial dysfunction and oxidative stress in the pathogenesis of alcohol- and obesity-induced fatty liver diseases.
Activation of Endothelial Nitric Oxide Synthase and Heme Oxygenase 1 Expression in Vasculature by Nitro-Fatty Acids.
Direct Measurement of Bioenergetic Stress in Cardiomyocytes Exposed to Hydrogen Peroxide and Protection by O-Glcnac.
Effect of alcohol and tobacco smoke on mtDNA damage and atherogenesis.
Action of reactive oxygen species on colonic mucus secretions.
Manganese porphyrin reduces renal injury and mitochondrial damage during ischemia/reperfusion.
Regulation of endothelial glutathione by ICAM-1 governs VEGF-A-mediated eNOS activity and angiogenesis.
Deoxyhemoglobin possesses dual functions as NO scavenger and a nitrite dependent NO generator: Insights from oxygen controlled vessel bioassays.
ICAM-1 cytoplasmic tail regulates endothelial cell redox status through an NADPH oxidase pathway.
Nitrite transport in erythrocytes: Evidence for oxygen-dependent modulation of export.
Purinergic signaling and kinase activation for survival in pulmonary oxidative stress and disease.
γ-Glutamyl transpeptidase is induced by 4-hydroxynonenal via EpRE/Nrf2 signaling in rat epithelial type II cells.
Endothelial Akt activation by hyperoxia: Role in cell survival.
Moderate hypoxia induces xanthine oxidoreductase activity in arterial endothelial cells.
Upregulation of immunoproteasomes by nitric oxide: Potential antioxidative mechanism in endothelial cells.
A sensitive method for the quantitative measurement of protein thiol modification in response to oxidative stress.
Activation of a novel isoform of methionine adenosyl transferase 2A and increased S-adenosylmethionine turnover in lung epithelial cells exposed to hyperoxia.
Chlorination modulates anti-inflammatory effects of isoflavones via PPAR gamma: Insights into the structure-activity relationships.
Chronic administration of nitrite therapy protects blood flow in the murine hind limb ischemia induced angiogenesis model.
Is S-nitrosohemoglobin dependent valsodilatation under allosteric control? Insights from a hemoglobin beta C93A mouse model.
Nitrite uptake by erythrocytes: Insights into mechanism and regulation.
Redox modulation of innate immune-derived pro-inflammatory third signals prevents diabetogenesis.
Sildenafil enhances ischemia-induced angiogenesis independent of nitric oxide.
The cytoplasmic tail of ICAM-1 regulates endothelial glutathione synthesis.
Evidence of cardiovascular protection by moderate alcohol: Role of nitric oxide.
HNE increases HO-1 through activation of the ERK pathway in pulmonary epithelial cells.
Lung epithelial cells release ATP during ozone exposure: Signaling for cell survival.
Antioxidant up-regulation and increased nuclear DNA protection play key roles in adaptation to oxidative stress in epithelial cells.
Mitochondrial dysfunction in cardiovascular disease.
Nitric oxide-induced resistance to hydrogen peroxide stress is a glutamate cysteine ligase activity-dependent process.
Stimulation of HIF-1α, HIF-2α, and VEGF by prolyl 4-hydroxylase inhibition in human lung endothelial and epithelial cells.
Mechanisms of glutamate cysteine ligase (GCL) induction by 4-hydroxynonenal.
4-Hydroxynonenal increases γ-glutamyl transpeptidase gene expression through mitogen-activated protein kinase pathways.
Nitroxia: The pathological consequence of dysfunction in the nitric oxide-cytochrome c oxidase signaling pathway.
Mitochondrial proteomics in free radical research.
Dietary modulation of vascular N-glycosylation: Mechanistic implications for anti-inflammatory effects of polyphenols.
Mass spectrometric methods for the determination of flavonoids in biological samples.
Human glutamate cysteine ligase gene regulation through the electrophile response element.
The powerhouse takes control of the cell; The role of mitochondria in signal transduction.
Introduction to serial reviews on 4-hydroxy-2-nonenal as a signaling molecule.
Weight loss and race modulate nitric oxide metabolism in overweight women.
The biochemistry of nitric oxide, nitrite, and hemoglobin: Role in blood flow regulation.
The biochemistry of nitric oxide, nitrite, and hemoglobin: Role in blood flow regulation.
Physiologic, pathologic and therapeutic implications for hemoglobin interactions with nitric oxide.
Mechanistic analysis of the immunomodulatory effects of a catalytic antioxidant on antigen-presenting cells: Implication for their use in targeting oxidation-reduction reactions in innate immunity.
Mechanistic re-examination of the reaction between nitrite and hemoglobin.
Nitrite activation of sGC in blood.
Proteomic analysis of skeletal muscle mitochondria reveal decreases in complex I and IV of the electron transport chain.
Neutrophil myeloperoxidase chlorinates and nitrates soy isoflavones and enhances their antioxidant properties.
MAPK pathways mediate hyperoxia-induced oncotic cell death in lung epithelial cells.
Novel SIN-1 reactive intermediates modulate chloride secretion across murine airway cells.
The differential modification of mitochondrial proteins by nitroxyl and nitric oxide.
Inhibition of human surfactant protein A function by oxidation intermediates of nitrite.
Mitochondria, nitric oxide, and cardiovascular dysfunction.
Urate produced during hypoxia protects heart proteins from peroxynitrite-mediated protein nitration.
4-Hydroxynonenal induces glutamate cysteine ligase through JNK in HBE1 cells.
Spatial mapping of pulmonary and vascular nitrotyrosine reveals the pivotal role of myeloperoxidase as a catalyst for tyrosine nitration in inflammatory diseases.
Mitochondria: Regulators of signal transduction by reactive oxygen and nitrogen species.
Erratum: AP-1 activation through endogenous H 2 O 2 generation by alveolar macrophages (Free Radical Biology and Medicine (2002) 32 (1304-1313) PII: S0891584902008407).
AP-1 activation through endogenous H2O2 generation by alveolar macrophages.
Mitochondrial function in response to cardiac ischemia-reperfusion after oral treatment with quercetin.
Hypothesis: The mitochondrial NO· signaling pathway, and the transduction of nitrosative to oxidative cell signals: An alternative function for cytochrome c oxidase.
Associations of weight loss and race with plasma NO3-/NO2-and 3-nitrotyrosine.
Contribution of mitochondria to oxidative stress associated with alcoholic liver disease.
ICAM-1 modulates GCLC expression and GSH localization within endothelial cells.
Induction of glutamate-cysteine ligase by oxidized lipids is mediated through antioxidant responsive element (ARE).
Nitric oxide and cellular respiration at low oxygen tension: A study on bovine aortic endothelial cells..
Antioxidant mechanisms of isoflavones in lipid systems: Paradoxical effects of peroxyl radical scavenging.
Mitochondrial tyrosine nitration precedes chronic allograft nephropathy.
Formation of nanomolar concentrations of S-nitroso-albumin in human plasma by nitric oxide.
Photocytotoxicity of lipofuscin in human retinal pigment epithelial cells.
Acidic fibroblast growth factor (FGF-1) signaling inhibits peroxynitrite-induced cell death during pancreatic tumorigenesis.
A metalloporphyrin-based superoxide dismutase mimetic inhibits type I diabetes.
Anti-inflammatory effects of soy-isoflavones: Inhibition of leukocyte-endothelial interactions.
Biphasic effects of cyclopentenone prostaglandins on glutathione induction and apoptosis in endothelial cells: insights into the cell signaling pathways initiated by oxidized phospholipids.
Cytoprotection mediated by oxidized lipids in endothelial cells.
Effect of inhibition of mitochondrial protein synthesis on nitric oxide dependent apoptosis.
Glutathione nitroso-sulfoxide: a potential reaction product of glutathione and peroxynitrite.
Mitochondrial sensitivity to nitric oxide is dependent on respiratory state.
Non-heme iron enhances the induction of glutamate-cysteine ligase and heme oxygenase-1 by nitric oxide in human endothelial cells.
Regulation of endothelial cell redox status by ICAM-1: Identification of a novel pathway governing endothelial cell reactivity.
The Saccharomyces cerevisiae Sln1p-Ssk1p two-component system mediates response to oxidative stress and in an oxidant-specific fashion.
Cell signaling by reactive nitrogen and oxygen species in atherosclerosis.
Biochemical aspects of the reaction of hemoglobin and NO: Implications for Hb-based blood substitutes.
Therapeutic applications of reactive oxygen and nitrogen species in human disease.
Peroxynitrite irreversibly decreases diastolic and systolic function in cardiac muscle.
Ethanol stimulates the production of reactive oxygen species at mitochondrial complexes I and III.
Effects of pyrrolidine dithiocarbamate on endothelial cells: Protection against oxidative stress.
Positive correlation between mammalian life span and cellular resistance to stress.
A critical appraisal of hydrogen peroxide and superoxide as signaling molecules using the JNK/SAPK map kinase pathway.
Is endothelium relaxing factor nitric oxide or an S-nitrosothiol? Insights from scavenging by hemoglobin.
Shear stress simulates cJUN N-terminal kinase (JNK) by activation of PI-3-kinase (PI3K), Akt and endothelial NO synthase (eNOS)..
Blue light-induced singlet oxygen generation by retinal lipofuscin in non-polar media.
Endothelial injury from a circulating mediator following rat liver ischemia.
A novel cellular mechanism for the antioxidant effects of the NF kappa B inhibitor pyrrolidine dithiocarbamate..
S-nitrosation of hemoglobin: Effects on O-2 delivery and antioxidant properties.
Nitric oxide regulation of superoxide-dependent lung injury: Oxidant- protective actions of endogenously produced and exogenously administered nitric oxide.
Oxidation of human low-density lipoprotein by soybean 15-lipoxygenase in combination with copper (II) or met-myoglobin.
Xanthine oxidase activity in the circulation of rats following hemorrhagic shock.
A sensitive fluorometric assay for measuring xanthine dehydrogenase and oxidase in tissues.
Oxidant inhibition of epithelial active sodium transport.