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Maintaining Myocardial Glucose Utilization in Diabetic Cardiomyopathy Accelerates Mitochondrial Dysfunction.
Serotonin regulates adult β-cell mass by stimulating perinatal β-cell proliferation.
Genetic determinants of glycated hemoglobin in type 1 diabetes.
Hepatic glucagon receptor signaling enhances insulin-stimulated glucose disposal in rodents.
Glucagon receptor signaling regulates energy metabolism via hepatic farnesoid X receptor and fibroblast growth factor 21.
Restructuring of the gut microbiome by intermittent fasting prevents retinopathy and prolongs survival in db/db mice.
Genome-wide association study of serum fructosamine and glycated albumin in adults without diagnosed diabetes: Results from the atherosclerosis risk in communities study.
miR-204 controls glucagon-like peptide 1 receptor expression and agonist function.
Hepatic but not extrahepatic insulin clearance is lower in African American than in European American women.
A low-frequency inactivating AKT2 variant enriched in the finnish population is associated with fasting insulin levels and type 2 diabetes risk.
Genetics of type 2 diabetes in U.S. Hispanic/Latino individuals: Results from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).
Gestational diabetes mellitus from inactivation of prolactin receptor and MafB in islet β-cells.
Skeletal muscle TRIB3 mediates glucose toxicity in diabetes and high-fat diet-induced insulin resistance.
Loss of NOX-derived superoxide exacerbates diabetogenic CD4 T-cell effector responses in type 1 diabetes.
Augmented STAT5 signaling bypasses multiple impediments to lactogen-mediated proliferation in human β-cells.
β-cell microRNAs: Small but powerful.
Unsticking the broken diabetic heart: O-GlcNAcylation and calcium sensitivity.
Growth hormone inhibits hepatic de novo lipogenesis in adult mice.
Response to Comment on Sofi et al. pH of drinking water influences the composition of gut microbiome and type 1 diabetes incidence. Diabetes 2014;63:632-644.
Loss of NADPH oxidase-derived superoxide skews macrophage phenotypes to delay type 1 diabetes.
Inhibition of Ca2+-independent phospholipase A2β (iPLA2β) ameliorates islet infiltration and incidence of diabetes in NOD mice.
A31: Rare and Common Exome Variants Are Associated with Fasting Glucose and Insulin Levels-The CHARGE-S Exome Chip and Sequencing Study.
BMI, RQ, diabetes, and sex affect the relationships between amino acids and clamp measures of insulin action in humans.
Epigenome-wide association study of fasting measures of glucose, insulin, and homa-ir in the genetics of lipid lowering drugs and diet network study.
GLP-1R responsiveness predicts individual gastric bypass efficacy on glucose tolerance in rats.
Bilirubin: A potential biomarker and therapeutic target for diabetic nephropathy.
Both acyl and des-acyl ghrelin regulate adiposity and glucose metabolism via central nervous system ghrelin receptors.
Downregulation of carnitine acyl-carnitine translocase by miRNAs 132 and 212 amplifies glucose-stimulated insulin secretion.
Effect of guanylate cyclase-C activity on energy and glucose homeostasis.
Islet-1 is essential for pancreatic β-cell function.
KSRP ablation enhances brown fat gene program in white adipose tissue through reduced miR-150 expression.
TRIB3 mediates glucose-induced insulin resistance via a mechanism that requires the hexosamine biosynthetic pathway.
GLP-1R agonism enhances adjustable gastric banding in diet-induced obese rats.
A431: Epigenetics of Fasting Insulin and Glucose Concentrations.
Fibroblast growth factor 21 mediates specific glucagon actions.
Islet a-, b-, and d-Cell development is controlled by the ldb1 coregulator, acting primarily with the islet-1 transcription factor.
Per2 mutation recapitulates the vascular phenotype of diabetes in the retina and bone marrow.
Clinical islet xenotransplantation: How close are we?.
Caloric restriction chronically impairs metabolic programming in mice.
Fat-specific DsbA-L overexpression promotes adiponectin multimerization and protects mice from diet-induced obesity and insulin resistance.
Preventing β-cell loss and diabetes with calcium channel blockers.
IL-21 is an antitolerogenic cytokine of the late-phase alloimmune response.
Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes.
Superoxide production by macrophages and T cells is critical for the induction of autoreactivity and type 1 diabetes.
Nuclear orphan receptor TAK1/TR4-deficient mice are protected against obesity-linked inflammation, hepatic steatosis, and insulin resistance.
Redox modulation protects islets from transplant-related injury.
Admixture Mapping of Type 2 Diabetes and Lipoprotein Subclasses in Gullah-Speaking African Americans in Project SuGAR.
Changes in Insulin Sensitivity in Overweight/Obese Patients Treated with Low-Dose, Controlled-Release Phentermine/Topiramate(PHEN/TPM).
Diabetes and Oral Health among Rural, Ethnically Diverse Older Adults.
Effects of Resistance Exercise and Aging on NR4A Protein Levels in Skeletal Muscle.
Enhanced Rat Islet Function and Survival In Vitro Using a Biomimetic Self-Assembled Nanomatrix Gel.
Improvements in Dyslipidemia and Other Cardiometabolic Disease Risk Factors with Low-Dose, Controlled-Release Phentermine/Topiramate (PHEN/TPM).
Initial Combination Therapy with Metformin plus Colesevelam Safely Achieves Glycemic and Lipid Goals with Less Diarrhea in Early Type 2 Diabetes Mellitus.
Lipid Metabolism Modulated by Macrophage Adiponectin Expression In Vivo.
Macrophage and T Cell ROS Production Is Critical for T1D Pathogenesis.
Metabolic Effects of Adipocyte-Specific NR4A3 Over-Expression in Mice.
Osteocalcin Effects on Cytokine Secretion by Adipose Tissue and Glucose Uptake in L6 Muscle Cells: Linking the Skeleton with Insulin Resistance and Inflammation.
The Safety and Tolerability of Metformin plus Colesevelam in Drug-Naive Patients with Early Type 2 Diabetes Mellitus.
Macrophage adiponectin expression improves insulin sensitivity and protects against inflammation and atherosclerosis.
Duration of lactation and incidence of the metabolic syndrome in women of reproductive age according to gestational diabetes mellitus status: A 20-year prospective study in CARDIA (Coronary Artery Risk Development in Young Adults).
Lack of TXNIP protects against mitochondria-mediated apoptosis but not against fatty acid-induced ER stress-mediated β-cell death.
HDL as a biomarker, potential therapeutic target, and therapy.
Adipose tissue exosome-like vesicles mediate activation of macrophage-induced insulin resistance.
FoxO1 links insulin resistance to proinflammatory cytokine IL-1β production in macrophages.
Islet-1 is required for the maturation, proliferation, and survival of the endocrine pancreas.
Apolipoprotein-Defined Lipoproteins in the DCCT/EDIC Cohort: Associations with Diabetic Nephropathy in Type 1 Diabetes.
Genes and Biochemical Pathways in Human Skeletal Muscle Affecting Resting Energy Expenditure and Fuel Partitioning.
Inhibition of Superoxide Synthesis Prevents T Cell Autoreactivity.
One-Year Treatment with VI-0521 in Type 2 Diabetes Demonstrates Continued Glycemic Improvement and Weight Loss.
Redox Modulation Ablates Adaptive Immune Effector Response by Inhibiting IL-12-IL-12R Signaling.
Genome-wide linkage scan in gullah-speaking african american families with type 2 diabetes: The sea islands genetic African American Registry (Project SuGAR).
Carbon monoxide and nitric oxide mediate cytoskeletal reorganization in microvascular cells via vasodilator-stimulated phosphoprotein phosphorylation: Evidence for blunted responsiveness in diabetes.
Effect of VI-0521 (phentermine and topiramate) in type 2 diabetes.
Genome-wide linkage scan in Gullah-speaking African American families with Type 2 diabetes: The Sea Islands Genetic African American Registry (Project SuGAR).
Metabolic syndrome traits and endothelial dysfunction: Role of ethnicity.
Osteocalcin is not just for bones: Effects on adipocytes and role in human metabolism.
Overexpression of adiponectin reduces lipid accumulation in human THP-1 macrophage foam cells.
Reactive oxygen species generation is necessary for diabetogenic T cell effector function.
Redox modulation impairs allograft rejection.
Redox modulation regulates T cell activation and effector function through a tumor necrosis factor alpha converting enzyme (TACE) dependent mechanism.
The HOMA index estimation of insulin resistance is affected by ethnicity.
Thioredoxin-interacting protein A critical link between glucose toxicity and β-cell apoptosis.
A 20-year prospective study of childbearing and incidence of diabetes in young women, controlling for glycemia before conception: The coronary artery risk development in young adults (CARDIA) study.
Body size and shape changes and the risk of diabetes in the diabetes prevention program.
Critical role of superoxide (O2-) production in the pathogenesis of autoimmune diabetes (T1D).
Ethnic differences in adiponectin multimer distribution and relationships with metabolic syndrome traits.
Fat depots and adipokines in morbidly obese individuals.
Functional study of Trb 3 related to diabetic skeletal muscle.
Pioglitazone therapy restores the coupling of electron transport to ATP synthesis in skeletal muscle of obese zucker rats.
Reactive oxygen species generation is necessary for autoimmune T cell effector function.
Genotype-by-sex interaction on fasting insulin concentration: The HyperGEN study.
Modulatory role of DR4- to DQ8-restricted CD4 T-cell responses and type 1 diabetes susceptibility.
Polymorphism in the transcription factor 7-Like 2 (TCF7L2) gene is associated with reduced insulin secretion in nondiabetic women.
Suppressed insulin signaling and increased apoptosis in Cd38-null islets.
A diabetes management program using diabetes-specific meal replacements and snack bars improves weight loss, metabolic parameters, and quality of life (QOL).
A role for C/EBP-delta in mitochondrial dysfunction and insulin resistance in skeletal muscle.
Blockade of the inflammatory third signal in conjunction with antigenic immunization as a potentially novel immunosuppression strategy.
CETP gene variation has pronounced independent effect on HDL levels and HDL particle size in type 1 diabetes.
Effects of short-term very low calorie diet (VLCD) on secretion of adipocytokines in human adipose tissue.
Redox modulation inhibits diabetogenic T cell activation and T1D.
Resistin autoregulates inflammatory cytokine production and induces insulin resistance in adipocytes.
The role of ER-stress in the antigenic response of the BDC-2.5 T cell.
Quantitative trait loci on chromosome 8q24 for pancreatic β-cell function and 7q11 for insulin sensitivity in obese nondiabetic white and black families: Evidence from genome-wide linkage scans in the NHLBI Hypertension Genetic Epidemiology Network (HyperGEN) study.
Adiponectin multimeric complexes and the metabolic syndrome trait cluster.
Adiponectin is lower among African Americans and is independently related to insulin sensitivity in children and adolescents.
Nonhuman primate models for diabetic ocular neovascularization using AAV2-mediated overexpression of vascular endothelial growth factor.
Adiponectin multimeric complexes and the metabolic syndrome trait cluster.
Administration of pioglitazone to LDL receptor-deficient mice inhibits progression of intimal lesions and expression of matrix metalloproteinases and adhesion molecules.
Catalytic antioxidant disruption of innate-mediated pro-inflammatory cytokine and reactive oxygen species third signal delays spontaneous autoimmune diabetes in the NOD mouse.
Dysregulation of mitochondria-related genes in skeletal muscle from insulin resistant humans is associated with suppression of transcription factors involved in mitochondrial biogenesis.
Lipid metabolism mediated by adipocyte lipid binding protein (ALBP/aP2) gene expression in human THP-1 macrophages.
Proteomics analysis of skeletal muscle mitochondria in type 2 diabetes reveals altered concentrations and oxidation of respiratory chain proteins.
Linkage analysis of diabetes status among hypertensive families: The hypertension genetc epidemiology network study.
Activated protein C preserves functional islet mass after intraportal transplantation: A novel link between endothelial cell activation, thrombosis, inflammation, and islet cell death.
Impaired Cardiac Efficiency and Increased Fatty Acid Oxidation in Insulin-Resistant ob/ob Mouse Hearts.
Regulation of resistin expression and circulating levels in obesity, diabetes, and fasting.
Associations of adiponectin with retinopathy in the DCCT/EDIC cohort: Influence of insulin resistance.
Disruption of pro-inflammatory cytokine and reactive oxygen species dependent third signal leads to antigen-specific hyporesponsiveness that is STAT-4 dependent.
Effects of atypical antipsychotic drugs on insulin action in adipocytes.
Genetic ablation of macrophage/neutrophil NADPH oxidase activity inhibits T1D development in NOD mice.
Overexpression of adiponectin but not resistin enhances adipocyte differentiation and insulin sensitivity.
Quelling oxidative stress during human islet isolation correlates with reduced NF-kappa B-dependent pro-inflammatory mediators: Implications for the development of footprint assays for transplant success.
Hexosamine Pathway Is Responsible for Inhibition by Diabetes of Phenylephrine-Induced Inotropy.
Beta-cell calcium-independent group VIA phospholipase A(2) (iPLA(2)beta): tracking iPLA(2)beta movements in response to stimulation with insulin secretagogues in INS-1 cells..
53 Suppl 1:S186-S189.
Islet Complex Lipids: Involvement in the Actions of Group VIA Calcium-Independent Phospholipase A2 in β-Cells.
Caspase-1 Is Not Required for Type 1 Diabetes in the NOD Mouse.
Activation of Vascular Endothelial Growth Factor Receptor-1 Sustains Angiogenesis and Bcl-2 Expression Via the Phosphatidylinositol 3-Kinase Pathway in Endothelial Cells.
Brain Death Significantly Reduces Isolated Pancreatic Islet Yields and Functionality In Vitro and In Vivo after Transplantation in Rats.
Linkage Analysis of a Composite Factor for the Multiple Metabolic Syndrome: The National Heart, Lung, and Blood Institute Family Heart Study.
Expression of constitutively active cGMP-dependent protein kinase prevents glucose stimulation of thrombospondin 1 expression and TGF-β activity.
Alterations in skeletal muscle caveolins 1 and 3 in human insulin resistance and obesity.
Relationship between insulin senstivity and intramyocellular lipid during short term very low calorie diet in obese type 2 diabetics.
Plasma prekallikrein: A risk marker for hypertension and nephropathy in type 1 diabetes.
Using genetic admixture to explain racial differences in insulin-related phenotypes.
Adeno-associated virus-mediated IL-10 gene therapy inhibits diabetes recurrence in syngeneic islet cell transplantation of NOD mice.
Effects of insulin resistance and type 2 diabetes on lipoprotein subclass particle size and concentration determined by nuclear magnetic resonance.
Troglitazone antagonizes metabolic effects of glucocorticoids in humans: Effects on glucose tolerance, insulin sensitivity, suppression of free fatty acids, and leptin.
Flotillin-1 expression in skeletal muscle is altered in insulin resistant humans.
Hepatic lipase gene polymorphism is a major determinant of HDL level and HDL size in men with type 1 diabetes in the DCCT/EDIC.
Therapeutic induction of diabetes resistance and antigen-specific hyporesponsiveness using a superoxide dismutase mimic (AEOL 10113).
Type 2 diabetes leads to progressive impairment of cardiac contractility.
A genome-wide scan for loci linked to plasma levels of glucose and HbA1c in a community-based sample of Caucasian pedigrees: The Framingham Offspring Study.
Longitudinal Study on Pubertal Insulin Resistance.
Effects of Insulin Resistance and type 2 diabetes on the nuclear magnetic resonance lipoprotein subclass profile.
Effects of race on the NMR lipoprotein profile and insulin resistance syndrome: Lipids and blood pressure are not influenced by insulin resistance in African Americans.
Postprandial glucose and insulin responses to dextrin-containing medical nutritional bars in persons with type 2 diabetes mellitus.
SNARE proteins (Syntaxin4, VAMP2, munc18) and skeletal muscle insulin resistance in rats and humans.
Erratum: Visceral fat, insulin sensitivity and upids in prepulbertal childre. (Diabetes 48: 1515-1521, 1999).
Visceral fat, insulin sensitivity, and lipids in prepubertal children. (vol 48, pg 1515, 1999).
Efficient ex vivo transduction of pancreatic islet cells with recombinant adeno-associated virus vectors.
Loss of the antiangiogenic pigment epithelium-derived factor in patients with angiogenic eye disease.
Successful reversal of streptozotocin-induced diabetes with stable allogeneic islet function in a preclinical model of type 1 diabetes.
Upregulation of glucose metabolism during intimal lesion formation is coupled to the inhibition of vascular smooth muscle cell apoptosis: Role of GSK3β.
Nuclear magnetic resonance (NMR)-determined lipoprotein subclass profile in the DCCT/EDIC cohort: Associations with retinopathy and nephropathy.
Nuclear magnetic resonance (NMR)-determined lipoprotein subclass profile in the DCCT/EDIC cohort: Effects of gender, HbAlc, and DCCT randomization group..
Nuclear magnetic resonance (NMR)-determined lipoprotein subclass profile: Effects of hyperglycemia, lipoprotein glycation, and comparison with standard lipid profile.
Paraoxonase genotype (192 Gln-Arg) and serum paraoxonase-arylesterase activity: Relationship with Type 1 diabetes and nephropathy.
Troglitazone is an effective therapeutic agent in patients with steroid-induced diabetes.
Cloning of a T-type Ca2+ channel isoform in insulin-secreting cells.
Visceral fat, insulin sensitivity, and lipids in prepubertal children.
Hyperfibrinogenemia is associated with nephropathy in type 1 diabetes.
Low birth weight is associated with reduced expression of GLUT4 and carnitine palmitoyltransferase-1 in adult skeletal muscle.
Plasminogen activator inhibitor-1 is increased in type 1 diabetes patients with hypertension.
Toward rational diagnostic criteria for the insulin resistance syndrome.
Troglitazone prevents glucocorticoid-induced insulin resistance in humans.
Apolipoprotein CIII polymorphism confers altered chemical composition of triglyceride-rich lipoprotein in type 1 diabetes.
Insulin resistance and defective glucose-insulin coupling in ketosis-prone type 2 diabetes of African-American youth.
The role of uncoupling proteins in metabolic fuel partitioning and human obesity.
Structure and organization of the human uncoupling protein 2 gene and identification of a common biallelic variant in Caucasian and African- American subjects.
Brief twice-weekly episodes of hypoglycemia reduce detection of clinical hypoglycemia in 1 diabetes mellitus.
Expression of mRNAs encoding uncoupling proteins in human skeletal muscle. Effects of obesity and diabetes.
Impact of nocturnal hypoglycemia on hypoglycemic cognitive dysfunction in type 1 diabetes.
Decreased insulin-stimulated Z-deoxyglucose uptake and impaired GLUT4 translocation in skeletal muscle of transgenic mice overexpressing glutamine: Fructose-6-phosphate amidotransferase..
Ketosis-prone NIDDM in African-American children..
NIDDM and obesity are associated with Protein Kinase C abnormalities in human skeletal muscle.
Insulin sensitivity and acute insulin response in african-americans, non-Hispanic whites, and Hispanics with NIDDM the insulin resistance atherosclerosis study.
Muscle rad expression and human metabolism: Potential role of the novel ras-related GTPase in energy expenditure and body composition.
Correlation of leptin and body fat in obese, lean, and lipodystrophic humans..
Dual energy X-ray absorptiometry (DXA) assessment of fat mass and distribution and its association with the insulin resistance syndrome (IRS)..
Fat and muscle tissue express a common abnormality in translocation/trafficking of GLUT4/vp165 containing vesicles in NIDDM..
The metabolic significance of leptin in humans..
Epidermal growth factor induces glucose storage in transgenic 3T3-L1 adipocytes overexpressing epidermal growth factor receptors.
Increased insulin resistance and insulin secretion in nondiabetic African-Americans and Hispanics compared with non-Hispanic whites: The Insulin Resistance Atherosclerosis Study.
ABNORMALITIES IN GLUT-4 TRANSLOCATION AND TRAFFICKING IN SKELETAL-MUSCLE CAUSE INSULIN-RESISTANCE IN HUMANS.
GLUCOSAMINE (GLMN) INDUCES INSULIN-RESISTANCE (IR) IN-VIVO BY AFFECTING GLUT 4 TRANSLOCATION IN SKELETAL-MUSCLE - IMPLICATIONS FOR GLUCOSE TOXICITY.
RAD EXPRESSION IN SKELETAL-MUSCLE OF TYPE-II DIABETICS.
MUSCLE GLUT 4 EXPRESSION IS A FAMILIAL TRAIT AND DETERMINES INSULIN SENSITIVITY IN HUMANS INDEPENDENT OF OBESITY.
THE GOLGI-APPARATUS IS NOT REQUIRED FOR INSULIN STIMULATION OF GLUCOSE-TRANSPORT AND GLUT-4 TRANSLOCATION IN RAT ADIPOCYTES.
Biological actions of insulin are differentially regulated by glucose and insulin in primary cultured adipocytes: Chronic ability to increase glycogen synthase activity.
Saturated fatty acid-induced insulin resistance in rat adipocytes.
Multiple defects in the adipocyte glucose transport system cause cellular insulin resistance in gestational diabetes. Heterogeneity in the number and a novel abnormality in subcellular localization of GLUT4 glucose transporters.
MECHANISMS UNDERLYING PERIPHERAL-NERVE GLUCOSE-UPTAKE SUPPRESSION IN DIABETES.
Amplification of insulin secretion by lipid messengers.
Multiple defects in the adipocyte glucose transport system cause cellular insulin resistance in gestational diabetes: Heterogeneity in the number and a novel abnormality in subcellular localization of GLUT4 glucose transporters.
Gene expression of GLUT4 in skeletal muscle from insulin-resistant patients with obesity, IGT, GDM, and NIDDM.
Glucose and insulin chronically regulate insulin action via different mechanisms in BC3H1 myocytes: Effects on glucose transporter gene expression.
Production of marked prolongation of islet xenograft survival (rat to mouse) by local release of mouse and rat antilymphocyte sera at transplant site.
Renal adaptation to dietary phosphate restriction in rats: Interactions with insulin and calcitriol.
Day-long integrated serum insulin and C-peptide profiles in patients with NIDDM. Correlation with urinary C-peptide excretion.
Interferon-mediated induction of Ia antigen expression on isolated murine whole islets and dispersed islet cells.
The effect of cyclosporin-A, low-temperature culture, and anti-Ia antibodies on prevention of rejection of rat islet allografts.
Glycation of skin collagen in type I diabetes mellitus. Correlation with long-term complications.
Insulin induces progressive insulin resistance in cultured rat adipocytes: Sequential effects at receptor and multiple postreceptor sites.
Factors related to learning and behavior in diabetics
The effect of insulin treatment on insulin secretion and insulin action in type II diabetes mellitus.
Comparison of monitoring blood vs. urine glucose in obese type II diabetics
Evidence for genetic admixture as a determinant in the occurrence of insulin-dependent diabetes mellitus in U.S. blacks.
Concordance and discrepancy in perceptions of diabetic adolescents' social behaviors: mother, father, child
HLA-A, -B, and -DR associations in type I diabetes mellitus with onset after age forty.
Stimulation of microvascular cyclic-AMP phosphodiesterase activity by insulin, spermine and concanavalin.
Perceived needs of diabetes patient educators
Metabolic effects of glucose insulin potassium (GIK) infusion during acute myocardial infarction (AMI).
Insulin secretion in protein-calorie malnutrition. I. Quantitative abnormalities and response to treatment..
Biochemistry of extrapancreatic tumor hypoglycemia..
Hyperglycemic, hyperosmolar, nonketoacidotic diabetes. A complication of steroid and immunosupressive therapy..