Positions

Selected Publications

Academic Article

Year Title Altmetric
2016 Pillars Article: Identification of a Putative Second T-cell Receptor. Nature. 1986. 322: 145-149.Journal of Immunology.  196:3509-3513. 2016
2012 Engaging basic scientists in translational research: identifying opportunities, overcoming obstacles.Journal of Translational Medicine.  10:72. 2012
2010 Pathway modulators and inhibitors.Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.].  Appendix 6:6. 2010
2010 Analysis of proteins: IntroductionCurrent protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.]2010
2010 Current Protocols in Molecular Biology: PrefaceCurrent protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.]2010
2009 Pathway modulators and inhibitors.Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.].  Appendix 6:6. 2009
2008 Diagnosis of thrombotic thrombocytopenic purpura with normal ADAMTS13 activity and absence of its inhibitor (anti-ADAMTS13 antibodies).American Journal of Hematology.  83:256. 2008
2007 Performance of the Sebia CAPILLARYS 2 for detection and immunotyping of serum monoclonal paraproteins.American Journal of Clinical Pathology.  128:293-299. 2007
2007 Bio*Medical informatics and genomic medicine: Research and trainingComputers and Biomedical Research.  40:1-4. 2007
2007 Electrospray ionisation-cleavable tandem nucleic acid mass tag-peptide nucleic acid conjugates: synthesis and applications to quantitative genomic analysis using electrospray ionisation-MS/MS.Nucleic Acids Research.  35:e28. 2007
2006 Timing of plasma exchange and rituximab for the treatment of thrombotic thrombocytopenic purpura.American Journal of Clinical Pathology.  126:965. 2006
2006 Spectrophotometric and colorimetric determination of protein concentration.Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.].  Chapter 10:Unit-10.1A. 2006
2006 Solution radioimmunoassay of proteins and peptides.Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.].  Chapter 10:Unit-10.24. 2006
2002 Electroelution of proteins from stained gels.Current protocols in immunology / edited by John E. Coligan ... [et al.].  Chapter 8:Unit-8.8. 2002
2001 Column chromatography of antibodies and fragments.Current protocols in immunology / edited by John E. Coligan ... [et al.].  Appendix 3:Appendix-3I. 2001
1999 Continuous quality improvement for point-of-care testing using background monitoring of duplicate specimens.Archives of Pathology and Laboratory Medicine.  123:824-828. 1999
1999 Estimating costs and turnaround times: presenting a user-friendly tool for analyzing costs and performance.Clinical Laboratory Management Review.  13:179-187. 1999
1999 Cost analysis for decision support: the case of comparing centralized versus distributed methods for blood gas testing.Journal of Healthcare Management.  44:207-215. 1999
1999 Curbing overutilization: the silver lining to HCFA compliance.Medical Laboratory Observer.  31. 1999
1998 Evaluating stat testing options in an academic health center: Therapeutic turnaround time and staff satisfactionClinical Chemistry.  44:1597-1603. 1998
1998 Stark choices for AHCs.Academic Medicine.  73:839-841. 1998
1997 A N(alpha)-acetyltransferase selectively transfers an acetyl group to NH2-terminal methionine residues: purification and partial characterization.BBA - Biochimica et Biophysica Acta.  1338:244-252. 1997
1997 A N(α)-acetyltransferase selectively transfers an acetyl group to NH2-terminal methionine residues: Purification and partial characterizationBBA - Proteins and Proteomics.  1338:244-252. 1997
1997 Using patient satisfaction as an indicator of the quality of laboratory services. Applying social science methods to evaluate outcomes in laboratory medicine.Clinical Laboratory Management Review.  11:93-102. 1997
1997 Training of doctors in the UK.Lancet.  349:436. 1997
1996 Acetyl-CoA hydrolase involved in acetate utilization in Saccharomyces cerevisiae.BBA - Biochimica et Biophysica Acta.  1297:105-109. 1996
1996 Automating clinical practice guidelines: a corporate-academic partnership.Clinical Laboratory Management Review.  10:120-123. 1996
1993 Isolation of a membrane-associated cathepsin D-like enzyme from the model antigen presenting cell, A20, and its ability to generate antigenic fragments from a protein antigen in a cell-free system.Archives of Biochemistry and Biophysics.  305:298-306. 1993
1993 Mapping of the glycoprotein 330 (Gp330) gene to mouse chromosome 2.Genomics.  17:780-781. 1993
1993 Immunodominance: a single amino acid substitution within an antigenic site alters intramolecular selection of T cell determinants.Journal of Immunology.  151:1852-1858. 1993
1992 Silencing of immunodominant epitopes by contiguous sequences in complex synthetic peptides.Cellular Immunology.  143:284-297. 1992
1992 Immunodominance: intermolecular competition between MHC class II molecules by covalently linked T cell epitopes.Journal of Immunology.  148:3034-3041. 1992
1992 Molecular cloning, sequencing, deletion, and overexpression of a methionine aminopeptidase gene from Saccharomyces cerevisiae.Journal of Biological Chemistry.  267:8007-8011. 1992
1991 Comparison of class I- and II-restricted T cell recognition of the identical peptide.European Journal of Immunology.  21:2781-2789. 1991
1991 Optimization of the fragmentation in a frit-fast atom bombardment ion source for the sequencing of peptides at the picomole level.Analytical Chemistry.  63:1978-1983. 1991
1991 Primary structure determination of peptides and enzymatically digested proteins using capillary liquid chromatography/mass spectrometry and rapid linked-scan techniques.Analytical Chemistry.  63:1091-1097. 1991
1991 Immunodominance: intramolecular competition between T cell epitopes.Journal of Immunology.  146:2137-2144. 1991
1991 Single amino acid substitution alters T cell determinant selection during antigen processing of Staphylococcus aureus nuclease.Journal of Immunology.  146:438-443. 1991
1990 Purification and characterization of a methionine aminopeptidase from Saccharomyces cerevisiae.Journal of Biological Chemistry.  265:19892-19897. 1990
1990 Freshly isolated Thy-1+ dendritic epidermal cells express T cell receptor gamma delta-CD3.Journal of Dermatological Science.  1:459-464. 1990
1990 Model peptides reveal specificity of N alpha-acetyltransferase from Saccharomyces cerevisiae.Journal of Biological Chemistry.  265:11576-11580. 1990
1990 A glucose-repressible gene encodes acetyl-CoA hydrolase from Saccharomyces cerevisiae.Journal of Biological Chemistry.  265:7413-7418. 1990
1990 Identification of methionine Nalpha-acetyltransferase from Saccharomyces cerevisiae.Journal of Biological Chemistry.  265:3603-3606. 1990
1990 Immunological activity of covalently linked T-cell epitopes.Nature.  343:381-383. 1990
1989 N alpha acetylation is required for normal growth and mating of Saccharomyces cerevisiae.Journal of Bacteriology.  171:5795-5802. 1989
1989 N alpha acetylation is required for normal growth and mating of Saccharomyces cerevisiae.Journal of Bacteriology.  171:5795-5802. 1989
1989 N alpha-acetyltransferase deficiency alters protein synthesis in Saccharomyces cerevisiae.FEBS Letters.  256:139-142. 1989
1989 Purification and characterization of an acetyl-CoA hydrolase from Saccharomyces cerevisiae.European Journal of Biochemistry.  184:21-28. 1989
1989 Molecular cloning and sequencing of a cDNA encoding N alpha-acetyltransferase from Saccharomyces cerevisiae.Journal of Biological Chemistry.  264:12339-12343. 1989
1989 Identical peptides recognized by MHC class I- and II-restricted T cells.Journal of Experimental Medicine.  170:279-289. 1989
1989 Structural organization of the rat acyl-peptide hydrolase gene.Nucleic Acids Research.  17:4397-4400. 1989
1989 Autoimmune target in Heymann nephritis is a glycoprotein with homology to the LDL receptor.Science.  244:1163-1165. 1989
1989 Relative contribution of "determinant selection" and "holes in the T-cell repertoire" to T-cell responses.Proceedings of the National Academy of Sciences.  86:4649-4653. 1989
1989 Cloning and sequence analysis of a rat liver cDNA encoding acyl-peptide hydrolase.Journal of Biological Chemistry.  264:8892-8899. 1989
1989 Murine MHC polymorphism and T cell specificities.Science.  244:572-575. 1989
1989 Prediction of major histocompatibility complex binding regions of protein antigens by sequence pattern analysis.Proceedings of the National Academy of Sciences.  86:3296-3300. 1989
1989 Molecular cloning and sequencing of genomic DNA encoding aminopeptidase I from Saccharomyces cerevisiae.Journal of Biological Chemistry.  264:6979-6983. 1989
1989 High molecular mass forms of basic fibroblast growth factor are initiated by alternative CUG codons.Proceedings of the National Academy of Sciences.  86:1836-1840. 1989
1988 Rapid separation of DNA restriction fragments using capillary electrophoresis.J Chromatogr.  458:323-333. 1988
1988 Rapid separation and purification of oligonucleotides by high-performance capillary gel electrophoresis.Proceedings of the National Academy of Sciences.  85:9660-9663. 1988
1988 Identification of distinct C3b and C4b recognition sites in the human C3b/C4b receptor (CR1, CD35) by deletion mutagenesis.Journal of Experimental Medicine.  168:1699-1717. 1988
1988 Purification and characterization of an N alpha-acetyltransferase from Saccharomyces cerevisiae.Journal of Biological Chemistry.  263:14948-14955. 1988
1988 T cell receptor gene usage in the response to lambda repressor cI protein. An apparent bias in the usage of a V alpha gene element.Journal of Experimental Medicine.  168:1081-1097. 1988
1988 Sequence determination of the mumps virus HN gene.Virology.  164:318-325. 1988
1988 Organization of the genes encoding complement receptors type 1 and 2, decay-accelerating factor, and C4-binding protein in the RCA locus on human chromosome 1.Journal of Experimental Medicine.  167:1271-1280. 1988
1988 Characterization of the catalytic domain of bovine adrenal tyrosine hydroxylase.Biochemical and Biophysical Research Communications.  151:1446-1453. 1988
1988 Structure of the human B lymphocyte receptor for C3d and the Epstein-Barr virus and relatedness to other members of the family of C3/C4 binding proteins.Journal of Experimental Medicine.  167:1047-1066. 1988
1988 Eosinophil granule cationic proteins: major basic protein is distinct from the smaller subunit of eosinophil peroxidase.Journal of Leukocyte Biology.  43:1-4. 1988
1988 Eosinophilic chemotactic factors of anaphylaxis.Methods in Enzymology.  162:170-174. 1988
1987 T lymphocyte response to bacteriophage lambda repressor cI protein. Recognition of the same peptide presented by Ia molecules of different haplotypes.Journal of Immunology.  139:3973-3980. 1987
1987 A rat histone H4 gene closely associated with the testis-specific H1t gene.Experimental Cell Research.  173:534-545. 1987
1987 T cell activation by processed antigen is equally blocked by I-E and I-A-restricted immunodominant peptides.European Journal of Immunology.  17:1605-1609. 1987
1987 Acyl-peptide hydrolase from rat liver. Characterization of enzyme reaction.Journal of Biological Chemistry.  262:11435-11445. 1987
1987 Structural characteristics of an antigen required for its interaction with Ia and recognition by T cells.Nature.  328:395-399. 1987
1987 Reactive sulfhydryl groups of alpha 39, a guanine nucleotide-binding protein from brain. Location and function.Journal of Biological Chemistry.  262:4501-4507. 1987
1987 High-performance capillary electrophoretic separation of bases, nucleosides, and oligonucleotides: retention manipulation via micellar solutions and metal additives.Analytical Chemistry.  59:1021-1027. 1987
1987 Human C3b/C4b receptor (CR1). Demonstration of long homologous repeating domains that are composed of the short consensus repeats characteristics of C3/C4 binding proteins.Journal of Experimental Medicine.  165:1095-1112. 1987
1987 Immune recognition of proteins: conclusions, dilemmas and enigmas.BioEssays.  6:112-116. 1987
1987 Immunological self, nonself discrimination.Science.  235:865-870. 1987
1987 Complete amino acid sequences of the heavy and light chain variable regions from two A/J mouse antigen nonbinding monoclonal antibodies bearing the predominant p-azophenyl arsonate idiotype.Biochemistry.  26:604-612. 1987
1987 Site-directed mutagenesis of stahphylococcal nuclease: Role of tyrosine residues in substrate binding and catalysisNucleosides and Nucleotides.  6:331-334. 1987
1986 Interaction of peptide antigens and class II major histocompatibility complex antigens.Nature.  324:260-262. 1986
1986 Molecular cloning and characterization of cDNA encoding the GTP-binding protein alpha i and identification of a related protein, alpha h.Proceedings of the National Academy of Sciences.  83:7663-7667. 1986
1986 The T cell repertoire for recognition of a phylogenetically distant protein antigen. Peptide specificity and MHC restriction of staphylococcal nuclease-specific T cell clones.Journal of Experimental Medicine.  164:897-910. 1986
1986 Purification of the B lymphocyte receptor for the C3d fragment of complement and the Epstein-Barr virus by monoclonal antibody affinity chromatography, and assessment of its functional capacities.Journal of Immunological Methods.  92:79-87. 1986
1986 Identification of a partial cDNA clone for the C3d/Epstein-Barr virus receptor of human B lymphocytes: homology with the receptor for fragments C3b and C4b of the third and fourth components of complement.Proceedings of the National Academy of Sciences.  83:5639-5643. 1986
1986 Identification of a putative second T-cell receptor.Nature.  322:145-149. 1986
1986 Molecular cartography of globular proteins with application to antigenic sites.Biopolymers.  25:863-883. 1986
1986 Human tumor cells synthesize an endothelial cell growth factor that is structurally related to basic fibroblast growth factor.Proceedings of the National Academy of Sciences.  83:2448-2452. 1986
1986 Antigenic determinants in proteins coincide with surface regions accessible to large probes (antibody domains)Proceedings of the National Academy of Sciences.  83:226-230. 1986
1986 Identification of functional regions on the I-Ab molecule by site-directed mutagenesisProceedings of the National Academy of Sciences.  83:747-751. 1986
1985 Rat epidermal growth factor: complete amino acid sequence. Homology with the corresponding murine and human proteins; isolation of a form truncated at both ends with full in vitro biological activity.European Journal of Biochemistry.  153:629-637. 1985
1985 Expression of murine 21-hydroxylase in mouse adrenal glands and in transfected Y1 adrenocortical tumor cells.Proceedings of the National Academy of Sciences.  82:7860-7864. 1985
1985 Identification of a partial cDNA clone for the human receptor for complement fragments C3b/C4b.Proceedings of the National Academy of Sciences.  82:7711-7715. 1985
1985 Purification and amino-terminal protein sequence analysis of the mumps virus fusion protein.Virology.  144:373-383. 1985
1985 Molecular studies of the atrial natriuretic factor gene.Hypertension.  7:I31-I34. 1985
1985 Combinational diversity within variable regions bearing the predominant anti-p-azophenylarsonate idiotype of strain A mice.Journal of Immunology.  134:2740-2747. 1985
1985 Conformation of the eosinophil chemotactic tetrapeptides and analogues in dimethyl sulfoxide. 1H n.m.r. studies.International journal of peptide and protein research.  25:337-346. 1985
1985 Rapid purification of the human C3b/C4b receptor (CR1) by monoclonal antibody affinity chromatographyJournal of Immunological Methods.  82:303-313. 1985
1985 Turns in peptides and proteins.Advances in Protein Chemistry.  37:1-109. 1985
1984 Nucleotide sequences of the human and mouse atrial natriuretic factor genes.Science.  226:1206-1209. 1984
1984 Complete amino acid sequence of the heavy-chain variable region from an A/J mouse antigen-nonbinding monoclonal antibody bearing the predominant arsonate idiotype.Biochemistry.  23:4726-4732. 1984
1984 The structure of rat preproatrial natriuretic factor as defined by a complementary DNA clone.Science.  225:324-326. 1984
1983 Structural correlates of idiotypy in the arsonate system.Annals of the New York Academy of Sciences.  418:48-64. 1983
1982 Hollow visceral myopathy: a light- and electron-microscopic study.American Journal of Surgical Pathology.  6:269-275. 1982
1980 Polydispersity of rat mast cell heparin. Implications for proteoglycan assembly.Journal of Biological Chemistry.  255:11753-11758. 1980

Education And Training

  • Master of Science in Medical Office Management / Administration, Tulane University
  • Full Name

  • John Smith