Positions

Overview

  • Dr. Wells’ research and clinical interest focuses on COPD, including COPD-associated pulmonary vascular disease. He is currently exploring the mechanism by which a tri-peptide extracellular matrix collagen fragment causes pulmonary hypertension in COPD through a translational research project that incorporates his interest in proteomics and imaging. Dr. Wells received his Internal Medicine and Pulmonary / Critical Care post-graduate training at the University of Alabama at Birmingham (UAB). He also served as Chief Medical Resident from 2008-2009. During his pulmonary fellowship, Dr. Wells was the first post-doctoral fellow at UAB selected to the T32 Training Grant in Lung Biology and Translational Medicine under the mentorship of Drs. Blalock and Dransfield in 2010.
  • Research Overview

  • Dr. Wells joined the Pulmonary Division in 2012 as an Assistant Professor. His research productivity has been recognized through publications, presentations at national meetings, and receipt of awards including the Sreedhar Nair Early Stage Investigator Award in COPD from the American Thoracic Society in 2015 and he was named one of the first Pittman Scholars at UAB in 2015. His research has been funded through intramural and extramural awards including a NIH/NHLBI K08 Mentored Scientist Career Development Award, a Cystic Fibrosis Research Development Grant, the Walter B. Frommeyer Jr. Fellowship in Investigational Medicine from UAB, the NIH/NHLBI Loan Repayment Program, as well as through clinical trials in COPD.
  • Investigator On

  • Private Grant  awarded by LUNG BIOTECHNOLOGY PBC 2020 - 2025
  • Private Grant  awarded by ARROWHEAD PHARMACEUTICALS INC. 2019 - 2024
  • A Novel Exosomal Inflammatory Pathway  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2017 - 2023
  • Combined Cardiopulmonary Failure in COPD: SPIROMICS II - HF  awarded by Columbia University 2019 - 2023
  • Private Grant  awarded by MEREO BIOPHARMA 4 LIMITED 2017 - 2022
  • AZD9688: A First in Class Disease Modifying Therapy to Treat Alpha-1 Antitrypsin Deficiency a Genetically Linked Orphan Disease  awarded by National Center for Advancing Translational Sciences/NIH/DHHS 2018 - 2022
  • Private Grant  awarded by PULMONX 2020 - 2022
  • Private Grant  awarded by LUNG BIOTECHNOLOGY PBC 2018 - 2022
  • SPIROMICS II: Biological Underpinnings of COPD Heterogeneity and Progression  awarded by University of California, San Francisco 2017 - 2022
  • Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS)  awarded by COPD FOUNDATION 2016 - 2022
  • Private Grant  awarded by PULMONX 2013 - 2022
  • Private Grant  awarded by GlaxoSmithKline 2018 - 2022
  • Private Grant  awarded by VERTEX PHARMACEUTICALS, INC. 2016 - 2021
  • Beta Blockers for the Prevention of Acute Exacerbations of COPD  awarded by DOD - ARMY MEDICAL RESEARCH ACQUISITION ACTIVITY 2015 - 2021
  • COPD Cachexia: Deciphering the Impact of Antioxidants, Iron and Mitochondrial Function Using 'Omics Approaches  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2020 - 2021
  • SPIROMICS GIC Support  awarded by University of North Carolina at Chapel Hill 2018 - 2021
  • Network Management Core (NEMO) for the Pulmonary Trials Cooperative (PTC) (RETHINC)  awarded by COPD FOUNDATION 2017 - 2021
  • Network Management Cote (NEMO) for the Pulmonary Trials Cooperative (PTC) (INSIGHT)  awarded by COPD FOUNDATION 2017 - 2021
  • Losartan Effects on Emphysema Progression (LEEP) COVID-19 Ancillary Study  awarded by American Lung Association 2020 - 2021
  • Network Management Core (NEMO) for the Pulmonary Trials Cooperative (PTC) LEEP (Losartan Effects on Emphysema Progression) Trial  awarded by American Lung Association 2017 - 2021
  • Private Grant  awarded by BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. ^ 2016 - 2021
  • Understanding the Origins of Early COPD  awarded by Weill (Joan and Sanford I.) Medical College of Cornell University 2020 - 2021
  • Fibroblast Growth Factor 23/Klotho Crosstalk and Airway Epithelial Senescence in COPD  awarded by National Institute on Aging/NIH/DHHS 2018 - 2020
  • Network Management Core (NEMO) for the Pulmonary Trials Cooperative (PTC) (RETHINC)  awarded by COPD FOUNDATION 2018 - 2019
  • Prostaglandin Inhibition for Emphysema  awarded by UNIVERSITY OF NEBRASKA 2015 - 2019
  • Research Development Program  awarded by Cystic Fibrosis Foundation ^ 2015 - 2019
  • Private Grant  awarded by PNEUMRX, INC. 2016 - 2019
  • Private Grant  awarded by PNEUMRX, INC. 2014 - 2019
  • Private Grant  awarded by GlaxoSmithKline 2017 - 2019
  • Private Grant  awarded by PEARL THERAPEUTICS 2018
  • Private Grant  awarded by PROTERIXBIO, INC. 2016 - 2018
  • Reliability of a Portable Device to Measure Respiratory and Step Rates  awarded by UNIVERSITY OF NEBRASKA, OMAHA 2017 - 2018
  • Private Grant  awarded by Gilead Sciences ^ 2015 - 2017
  • Network Management Core (NEMO) for the Pulmonary Trials Cooperative (PTC) RETHINC (Redefining Therapy in Early COPD)  awarded by University of Pittsburgh The 2017
  • Network Management Core (NEMO) for the Pulmonary Trials Cooperative (PTC) INSIGHT (Intervention Study in Overweight Patients with COPD)  awarded by University of Pittsburgh The 2016 - 2017
  • Private Grant  awarded by PNEUMRX, INC. 2016 - 2017
  • Private Grant  awarded by ASTRAZENECA PHARMACEUTICALS LP 2014 - 2017
  • Airways Clinical Research Center (ACRC)  awarded by American Lung Association 2016 - 2017
  • Private Grant  awarded by YUNGJIN PHARM. CO.,LTD. 2015 - 2017
  • Private Grant  awarded by NOVARTIS PHARMACEUTICALS CORPORATION 2015 - 2016
  • Private Grant  awarded by SPECTRAL MEDICAL, INC. 2010 - 2016
  • Age Related Differences in Parametrics Response Mapping in COPD (Martinez Supplement)  awarded by University of Michigan 2015 - 2016
  • (Spiromics) SubPopulations and InteRmediate Outcome Measures in COPD Study  awarded by WAKE FOREST UNIVERSITY 2012 - 2016
  • (Spiromics) SubPopulations and InteRmediate Outcome Measures in COPD Study - Administrative Core  awarded by WAKE FOREST UNIVERSITY 2012 - 2016
  • (Spiromics) SubPopulations and InteRmediate Outcome Measures in COPD Study - Bronchoscopy - Project 1  awarded by WAKE FOREST UNIVERSITY 2012 - 2016
  • (Spiromics) SubPopulations and InteRmediate Outcome Measures in COPD Study - Exacerbation - Project 2  awarded by WAKE FOREST UNIVERSITY 2012 - 2016
  • Private Grant  awarded by GlaxoSmithKline 2015 - 2016
  • Private Grant  awarded by GlaxoSmithKline 2014 - 2016
  • Symbicort in HRCT-Defined Airway Predominant COPD  awarded by NATIONAL JEWISH MEDICAL RESEARCH CENTER 2014 - 2016
  • Private Grant  awarded by NOVARTIS PHARMACEUTICALS CORPORATION 2015
  • Pharmacogenomics of Inhaled Corticosteroids to Reduce COPD Exacerbations  awarded by Brigham and Women's Hospital 2013 - 2015
  • UAB Research Development Program Component II - Overall Program  awarded by Cystic Fibrosis Foundation ^ 2015
  • Private Grant  awarded by GlaxoSmithKline 2011 - 2015
  • Kit Inhibition in Asthma (KIA)  awarded by Brigham and Women's Hospital 2012 - 2015
  • Private Grant  awarded by PEARL THERAPEUTICS 2013 - 2015
  • Private Grant  awarded by FOREST LABORATORIES, INC. 2012 - 2014
  • Private Grant  awarded by PEARL THERAPEUTICS 2014
  • Private Grant  awarded by BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. ^ 2013 - 2014
  • Private Grant  awarded by MedImmune 2012 - 2014
  • Private Grant  awarded by JANSSEN RESEARCH & DEVELOPMENT, LLC 2010 - 2014
  • Private Grant  awarded by AERIS THERAPEUTICS, INC. 2012 - 2013
  • Private Grant  awarded by Pfizer Pharmaceuticals 2012 - 2013
  • Private Grant  awarded by GlaxoSmithKline 2012 - 2013
  • Education And Training

  • Master of Science in Health Professions and Related Programs, University of Alabama at Birmingham 2018
  • Doctor of Medicine, The University of Texas Health Science Center at Houston 2005
  • UAB Hospital, Internship 2006
  • UAB Hospital, Residency 2008
  • UAB Hospital, Postdoctoral Fellowship 2012
  • Full Name

  • James Wells