Positions

Overview

  • Dr. Meador-Woodruff received his BS in Chemistry from the University of Richmond, and his MD from the Medical College of Virginia. He then moved to Ann Arbor, and completed a combined residency in psychiatry and a research fellowship at the University of Michigan. After completing his research training, he joined the faculty of the Department of Psychiatry and the Mental Health Research Institute at the University of Michigan, where he held administrative positions including Associate Chair for Research and Vice Chair. He left Michigan in April 2006 to become the Heman E. Drummond Professor and Chairman of the Department of Psychiatry of University of Alabama at Birmingham (UAB). He moved his lab largely intact to UAB.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2019 Abnormal ER quality control of neural GPI-anchored proteins via dysfunction in ER export processing in the frontal cortex of elderly subjects with schizophreniaTranslational Psychiatry.  9. 2019
    2019 Fractionation of subcellular compartments from human brain tissueMethods in Molecular Biology.  1941:201-223. 2019
    2019 Intracellular compartment-specific proteasome dysfunction in postmortem cortex in schizophrenia subjectsMolecular Psychiatry2019
    2019 Kinase network dysregulation in a human induced pluripotent stem cell model of DISC1 schizophreniaMolecular Omics.  15:173-188. 2019
    2018 Abnormal expression of ER quality control and ER associated degradation proteins in the dorsolateral prefrontal cortex in schizophreniaSchizophrenia Research.  197:484-491. 2018
    2017 Abnormalities of signal transduction networks in chronic schizophrenianpj Schizophrenia.  3. 2017
    2017 Actin polymerization is reduced in the anterior cingulate cortex of elderly patients with schizophreniaTranslational Psychiatry.  7. 2017
    2017 Pre-clinical Medical Students as the Primary Longitudinal Provider of Psychiatric Care in the Outpatient Setting: A Novel Training ModelAcademic Psychiatry.  41:538-541. 2017
    2017 Altered fucosyltransferase expression in the superior temporal gyrus of elderly patients with schizophreniaSchizophrenia Research.  182:66-73. 2017
    2017 Abnormalities of signal transduction networks in chronic schizophrenia.npj Schizophrenia.  3:30. 2017
    2016 Decreased protein S-palmitoylation in dorsolateral prefrontal cortex in schizophreniaSchizophrenia Research.  177:78-87. 2016
    2016 Cell-specific abnormalities of glutamate transporters in schizophrenia: Sick astrocytes and compensating relay neurons?Molecular Psychiatry.  21:823-830. 2016
    2016 Shaping plasticity: Alterations in glutamate transporter localization as a pathophysiological mechanism in severe mental illness.Molecular Psychiatry.  21:723. 2016
    2016 Changes in cortical N-methyl-d-aspartate receptors and post-synaptic density protein 95 in schizophrenia, mood disorders and suicideAustralian and New Zealand Journal of Psychiatry.  50:275-283. 2016
    2016 Protein Expression of Proteasome Subunits in Elderly Patients with SchizophreniaNeuropsychopharmacology.  41:896-905. 2016
    2016 Decreased expression of cortactin in the schizophrenia brainNeuroReport.  27:145-150. 2016
    2016 Cortical PGC-1?-dependent transcripts are reduced in postmortem tissue from patients with schizophreniaSchizophrenia Bulletin.  42:1009-1017. 2016
    2015 Abnormal subcellular localization of GABA A receptor subunits in schizophrenia brainTranslational Psychiatry.  5. 2015
    2015 Glutamate transporter splice variant expression in an enriched pyramidal cell population in schizophreniaTranslational Psychiatry.  5. 2015
    2015 Abnormal N-acetylglucosaminyltransferase expression in prefrontal cortex in schizophreniaSchizophrenia Research.  166:219-224. 2015
    2015 Corrigenda - Postmortem Brain: An Underutilized Substrate for Studying Severe Mental Illness (Neuropsychopharmacology Reviews (2014) 39, (65-87) DOI: 10.1038/npp.2013.239)Neuropsychopharmacology.  40:1307. 2015
    2014 Altered serine/threonine kinase activity in schizophreniaBrain Research.  1568:42-54. 2014
    2014 Evolutionarily conserved pattern of AMPA receptor subunit glycosylation in mammalian frontal cortexPLoS ONE.  9. 2014
    2014 N-glycosylation of GABAA receptor subunits is altered in schizophreniaNeuropsychopharmacology.  39:528-537. 2014
    2014 Abnormal partitioning of hexokinase 1 suggests disruption of a glutamate transport protein complex in schizophreniaSchizophrenia Research.  154:1-13. 2014
    2014 Alterations of the myristoylated, alanine-rich C kinase substrate (MARCKS) in prefrontal cortex in schizophreniaSchizophrenia Research.  154:36-41. 2014
    2014 Increased G protein-coupled receptor kinase (GRK) expression in the anterior cingulate cortex in schizophreniaSchizophrenia Research.  159:130-135. 2014
    2014 Postmortem brain: An underutilized substrate for studying severe mental illnessNeuropsychopharmacology.  39:65-87. 2014
    2013 Dysfunction of the ubiquitin proteasome and ubiquitin-like systems in schizophreniaNeuropsychopharmacology.  38:1910-1920. 2013
    2013 N-linked glycosylation of cortical N-methyl-D-aspartate and kainate receptor subunits in schizophreniaNeuroReport.  24:688-691. 2013
    2013 Erratum: Gene expression of glutamate metabolizing enzymes in the hippocampal formation in human temporal lobe epilepsy (Epilepsia (2013) 54 228-238)Epilepsia.  54:1140. 2013
    2013 Transmembrane AMPA receptor regulatory protein (TARP) dysregulation in anterior cingulate cortex in schizophreniaSchizophrenia Research.  147:32-38. 2013
    2013 Abnormal N-linked glycosylation of cortical AMPA receptor subunits in schizophreniaSchizophrenia Research.  146:177-183. 2013
    2013 Abnormal expression of glutamate transporters in temporal lobe areas in elderly patients with schizophreniaSchizophrenia Research.  144:1-8. 2013
    2013 Gene expression of glutamate metabolizing enzymes in the hippocampal formation in human temporal lobe epilepsyEpilepsia.  54:228-238. 2013
    2012 Upregulation of cornichon transcripts in the dorsolateral prefrontal cortex in schizophreniaNeuroReport.  23:1031-1034. 2012
    2012 Ampa receptor subunit expression in the endoplasmic reticulum in frontal cortex of elderly patients with schizophreniaPLoS ONE.  7. 2012
    2012 Recent advances in targeting the ionotropic glutamate receptors in treating schizophreniaCurrent Pharmaceutical Biotechnology.  13:1535-1542. 2012
    2012 Abnormalities of the Duo/Ras-related C3 botulinum toxin substrate 1/p21-activated kinase 1 pathway drive myosin light chain phosphorylation in frontal cortex in schizophreniaBiological Psychiatry.  71:906-914. 2012
    2012 Expression of equilibrative nucleoside transporter type 1 protein in elderly patients with schizophreniaNeuroReport.  23:224-227. 2012
    2012 Abnormal activity of the MAPK- and cAMP-associated signaling pathways in frontal cortical areas in postmortem brain in schizophreniaNeuropsychopharmacology.  37:896-905. 2012
    2012 Regional differences in expression of β-tubulin isoforms in schizophreniaSchizophrenia Research.  135:181-186. 2012
    2012 Glutamate receptor abnormalities in schizophrenia: Implications for innovative treatmentsBiomolecules && Therapeutics.  20:1-18. 2012
    2011 Glutamatergic gene expression is specifically reduced in thalamocortical projecting relay neurons in schizophreniaBiological Psychiatry.  70:646-654. 2011
    2011 Endosomal trafficking of AMPA receptors in frontal cortex of elderly patients with schizophreniaSchizophrenia Research.  130:260-265. 2011
    2011 Novel approaches to the study of postmortem brain in psychiatric illness: Old limitations and new challengesBiological Psychiatry.  69:127-133. 2011
    2011 Innovative approach to research training: Research colloquium for junior investigatorsAcademic Psychiatry.  35:11-14. 2011
    2010 Increased cortical expression of an RNA editing enzyme occurs in major depressive suicide victimsNeuroReport.  21:993-997. 2010
    2010 Evidence for abnormal forward trafficking of AMPA receptors in frontal cortex of elderly patients with schizophreniaNeuropsychopharmacology.  35:2110-2119. 2010
    2010 Expression of the NR2B-NMDA receptor subunit and its Tbr-1/CINAP regulatory proteins in postmortem brain suggest altered receptor processing in schizophreniaSynapse.  64:495-502. 2010
    2010 Expression of the NR2B-NMDA receptor trafficking complex in prefrontal cortex from a group of elderly patients with schizophreniaSchizophrenia Research.  119:198-209. 2010
    2010 Parvalbumin deficiency and GABAergic dysfunction in mice lacking PGC-1αJournal of Neuroscience.  30:7227-7235. 2010
    2010 Late emerging effects of prenatal and early postnatal nicotine exposure on the cholinergic system and anxiety-like behaviorNeurotoxicology and Teratology.  32:336-345. 2010
    2010 Abnormal glycosylation of EAAT1 and EAAT2 in prefrontal cortex of elderly patients with schizophreniaSchizophrenia Research.  117:92-98. 2010
    2009 Vesicular glutamate transporter mRNA expression in the medial temporal lobe in major depressive disorder, bipolar disorder, and schizophreniaBipolar Disorders.  11:711-725. 2009
    2009 Decreased expression of NMDA receptor-associated proteins in frontal cortex of elderly patients with schizophreniaNeuroReport.  20:1019-1022. 2009
    2009 Expression of four housekeeping proteins in elderly patients with schizophreniaJournal of Neural Transmission.  116:487-491. 2009
    2009 Identification of novel targets for PGC-1α and histone deacetylase inhibitors in neuroblastoma cellsBiochemical and Biophysical Research Communications.  379:578-582. 2009
    2009 Expression of transcripts for myelin related genes in postmortem brain from cocaine abusersNeurochemical Research.  34:46-54. 2009
    2008 Abnormal expression of glutamate transporter and transporter interacting molecules in prefrontal cortex in elderly patients with schizophreniaSchizophrenia Research.  104:108-120. 2008
    2008 Role of glutamate in schizophrenia: Integrating excitatory avenues of researchExpert Review of Neurotherapeutics.  8:1389-1406. 2008
    2008 Cortical expression of glial fibrillary acidic protein and glutamine synthetase is decreased in schizophreniaSchizophrenia Research.  103:71-82. 2008
    2008 Lamina-specific abnormalities of NMDA receptor-associated postsynaptic protein transcripts in the prefrontal cortex in schizophrenia and bipolar disorderNeuropsychopharmacology.  33:2175-2186. 2008
    2008 Contribution of cystine-glutamate antiporters to the psychotomimetic effects of phencyclidineNeuropsychopharmacology.  33:1760-1772. 2008
    2008 Altered Vesicular Glutamate Transporter Expression in the Anterior Cingulate Cortex in SchizophreniaBiological Psychiatry.  63:766-775. 2008
    2007 Abnormal glutamate receptor expression in the medial temporal lobe in schizophrenia and mood disordersNeuropsychopharmacology.  32:1888-1902. 2007
    2007 Expression of transcripts for myelination-related genes in the anterior cingulate cortex in schizophreniaSchizophrenia Research.  90:15-27. 2007
    2007 NMDA receptors and schizophreniaCurrent Opinion in Pharmacology.  7:48-55. 2007
    2007 Decreased NR1, NR2A, and SAP102 transcript expression in the hippocampus in bipolar disorderBrain Research.  1127:108-118. 2007
    2006 Lamina-specific abnormalities of AMPA receptor trafficking and signaling molecule transcripts in the prefrontal cortex in schizophreniaSynapse.  60:585-598. 2006
    2006 Dopamine receptor signaling molecules are altered in elderly schizophrenic cortexSynapse.  60:271-279. 2006
    2006 Plasma copper, iron, ceruloplasmin and ferroxidase activity in schizophreniaSchizophrenia Research.  86:167-171. 2006
    2006 Altered NMDA receptor expression in schizophreniaMolecular Psychiatry.  11:705. 2006
    2006 Changes in NMDA receptor subunits and interacting PSD proteins in dorsolateral prefrontal and anterior cingulate cortex indicate abnormal regional expression in schizophreniaMolecular Psychiatry.  11:737-747. 2006
    2006 Up-regulation of NMDA receptor subunit and post-synaptic density protein expression in the thalamus of elderly patients with schizophreniaJournal of Neurochemistry.  98:1114-1125. 2006
    2006 Serine racemase protein expression in cortex and hippocampus in schizophreniaNeuroReport.  17:1181-1185. 2006
    2006 Expression of excitatory amino acid transporter interacting protein transcripts in the thalamus in schizophreniaSynapse.  59:394-402. 2006
    2006 Glutamatergic mechanisms in schizophrenia: Current conceptsCurrent Psychosis and Therapeutics Reports.  4:27-34. 2006
    2006 Reply to Balcar and Nanitsos. Reply: Autoradiography of [ 3H]aspartate and glutamate transport in schizophrenia [2]Neuropsychopharmacology.  31:687-688. 2006
    2005 Abnormal striatal expression of transcripts encoding NMDA interacting PSD proteins in schizophrenia, bipolar disorder and major depressionSchizophrenia Research.  78:87-93. 2005
    2005 Dopaminergic abnormalities in select thalamic nuclei in schizophrenia: Involvement of the intracellular signal integrating proteins calcyon and spinophilinAmerican Journal of Psychiatry.  162:1859-1871. 2005
    2005 Metabotropic glutamate receptor protein expression in the prefrontal cortex and striatum in schizophreniaSynapse.  57:123-131. 2005
    2005 Cortical glutamatergic markers in schizophreniaNeuropsychopharmacology.  30:1521-1531. 2005
    2005 Dopaminergic regulation of orexin neuronsEuropean Journal of Neuroscience.  21:2993-3001. 2005
    2005 Increased expression of glutaminase and glutamine synthetase mRNA in the thalamus in schizophreniaSchizophrenia Research.  75:27-34. 2005
    2005 Neurochemical markers for schizophrenia, bipolar disorder, and major depression in postmortem brainsBiological Psychiatry.  57:252-260. 2005
    2005 Distribution of the NMDA receptor NR3A subunit in the adult pig-tail macaque brainJournal of Chemical Neuroanatomy.  29:157-172. 2005
    2004 NR3A NMDA receptor subunit mRNA expression in schizophrenia, depression and bipolar disorderSchizophrenia Research.  71:361-370. 2004
    2004 Thalamic dysfunction in schizophrenia: Neurochemical, neuropathological, and in vivo imaging abnormalitiesSchizophrenia Research.  69:237-253. 2004
    2004 Abnormalities of the NMDA receptor and associated intracellular molecules in the thalamus in schizophrenia and bipolar disorderNeuropsychopharmacology.  29:1353-1362. 2004
    2004 Molecular abnormalities of the hippocampus in severe psychiatric illness: Postmortem findings from the Stanley Neuropathology ConsortiumMolecular Psychiatry.  9:609-620. 2004
    2004 Molecular abnormalities of the hippocampus in severe psychiatric illness: Postmortem findings from the Stanley Neuropathology ConsortiumMolecular Psychiatry.  9:544. 2004
    2004 Neurocognitive measures of prefrontal cortical dysfunction in schizophreniaSchizophrenia Research.  68:65-73. 2004
    2004 Effects of 6-Cyano-7-nitroquinoxaline-2,3-dione on Nicotinic Receptor Subunit Transcript Expression in the Rat BrainSynapse.  52:62-72. 2004
    2004 Expression of the ionotropic glutamate receptor subunits and NMDA receptor-associated intracellular proteins in the substantia nigra in schizophreniaBrain Research.  121:60-69. 2004
    2004 Gender-Specific Gene Expression in Post-Mortem Human Brain: Localization to Sex ChromosomesNeuropsychopharmacology.  29:373-384. 2004
    2004 Expression of Transcripts Encoding AMPA Receptor Subunits and Associated Postsynaptic Proteins in the Macaque BrainJournal of Comparative Neurology.  468:530-554. 2004
    2004 Calcyon Transcript Expression in Macaque BrainJournal of Comparative Neurology.  468:264-276. 2004
    2004 Neurofilament subunit protein abnormalities in the thalamus in schizophreniaThalamus and Related Systems.  2:265-272. 2004
    2003 Differential effects of antipsychotics on haloperidol-induced vacuous chewing movements and subcortical gene expression in the ratEuropean Journal of Pharmacology.  477:101-112. 2003
    2003 Altered transcript expression of NMDA receptor-associated postsynaptic proteins in the thalamus of subjects with schizophreniaAmerican Journal of Psychiatry.  160:1100-1109. 2003
    2003 DNA microarray analysis of functionally discrete human brain regions reveals divergent transcriptional profilesNeurobiology of Disease.  14:240-250. 2003
    2002 Ontogeny of ionotropic glutamate receptor subunit expression in the rat hippocampusDevelopmental Brain Research.  139:227-236. 2002
    2002 Striatal Excitatory Amino Acid Transporter Transcript Expression in Schizophrenia, Bipolar Disorder, and Major Depressive DisorderNeuropsychopharmacology.  26:368-375. 2002
    2002 Nucleus-specific expression of NMDA receptor-associated postsynaptic density proteins in primate thalamusThalamus and Related Systems.  1:303-316. 2002
    2001 Gene expression in schizophrenia [9]American Journal of Psychiatry.  158:1740-1741. 2001
    2001 Expression of excitatory amino acid transporter transcripts in the thalamus of subjects with schizophreniaAmerican Journal of Psychiatry.  158:1393-1399. 2001
    2001 Vesicular glutamate transporter transcript expression in the thalamus in schizophreniaNeuroReport.  12:2885-2887. 2001
    2001 Striatal ionotropic glutamate receptor expression in schizophrenia, bipolar disorder, and major depressive disorderBrain Research Bulletin.  55:631-640. 2001
    2001 Ontogeny of ionotropic glutamate receptor expression in human fetal brainDevelopmental Brain Research.  127:123-133. 2001
    2001 Abnormal kainate receptor expression in prefrontal cortex in schizophreniaNeuropsychopharmacology.  24:545-552. 2001
    2000 Ionotropic glutamate receptor modulation preferentially affects NMDA receptor expression in rat hippocampusSynapse.  38:294-304. 2000
    2000 Ionotropic glutamate receptor binding and subunit mRNA expression in thalamic nuclei in schizophreniaAmerican Journal of Psychiatry.  157:1811-1823. 2000
    2000 New initiative: Neuropsychopharmacology online rapid publicationNeuropsychopharmacology.  23:221-222. 2000
    2000 Nucleus-specific expression of ionotropic glutamate receptor subunit mRNAs and binding sites in primate thalamusBrain Research.  79:1-17. 2000
    2000 Metabotropic glutamate receptor mRNA expression in the schizophrenic thalamusBiological Psychiatry.  47:22-28. 2000
    1999 Ionotropic glutamate receptor modulation of 5-HT6 and 5-HT7 mRNA expression in rat brainNeuropsychopharmacology.  21:341-351. 1999
    1999 Nicotine withdrawal and psychiatric symptoms in cigarette smokers with schizophreniaNeuropsychopharmacology.  21:195-202. 1999
    1999 Effects of clozapine and haloperidol on 5-HT6 receptor mRNA levels in rat brainSchizophrenia Research.  38:7-12. 1999
    1999 On the distribution patterns of D1, D2, tyrosine hydroxylase and dopamine transporter immunoreactivities in the ventral striatum of the ratNeuroscience.  89:473-489. 1999
    1999 Acute feasibility and safety of a smoking reduction strategy for smokers with schizophreniaNicotine and Tobacco Research.  1:53-57. 1999
    1998 AMPA receptor binding and subunit mRNA expression in prefrontal cortex and striatum of elderly schizophrenicsNeuropsychopharmacology.  19:278-286. 1998
    1998 Differential prevalence of cigarette smoking in patients with schizophrenic vs mood disordersSchizophrenia Research.  33:113-118. 1998
    1998 The role of life events in onset and recurrent episodes of schizophrenia and schizoaffective disorderJournal of Psychiatric Research.  32:283-288. 1998
    1998 Tardive dyskinesia, clozapine, and treatment responseProgress in Neuro-Psychopharmacology and Biological Psychiatry.  22:567-573. 1998
    1998 Nicotine dependence in schizophrenia: Clinical phenomena and laboratory findingsAmerican Journal of Psychiatry.  155:1490-1501. 1998
    1997 Clozapine-reserpine combination for refractory psychosisSchizophrenia Research.  25:259-260. 1997
    1997 Antipsychotic regulation of hippocampal dopamine receptor messenger RNA expressionBiological Psychiatry.  42:155-164. 1997
    1997 Clozapine and haloperidol differentially affect AMPA and kainate receptor subunit mRNA levels in rat cortex and striatumBrain Research.  47:331-338. 1997
    1997 Linking the family of D2 receptors to neuronal circuits in human brain: Insights into schizophreniaNeuropsychopharmacology.  16:375-384. 1997
    1997 Dopamine receptor transcript expression in striatum and prefrontal and occipital cortex: Focal abnormalities in orbitofrontal cortex in schizophreniaArchives of General Psychiatry.  54:1089-1095. 1997
    1997 EditorialJournal of Psychiatric Research.  31:157-158. 1997
    1997 Serotonin transporter mRNA in schizophrenia (multiple letters) [1]Molecular Psychiatry.  2:446-447. 1997
    1996 Lack of dopamine receptor agonists effect on striatal dopamine transporter binding sitesBrain Research.  742:313-316. 1996
    1996 Differential regulation of hippocampal AMPA and kainate receptor subunit expression by haloperidol and clozapineMolecular Psychiatry.  1:41-53. 1996
    1996 Smoking, smoking withdrawal and schizophrenia: Case reports and a review of the literatureSchizophrenia Research.  22:133-141. 1996
    1996 Differential effects of clozapine and haloperidol on dopamine receptor mRNA expression in rat striatum and cortexBrain Research.  41:241-249. 1996
    1996 Dopamine receptor gene expression in hippocampus is differentially regulated by the NMDA receptor antagonist MK-801European Journal of Pharmacology.  306:257-264. 1996
    1996 Differential regulation, by MK-801, of dopamine receptor gene expression in rat nigrostriatal and mesocorticolimbic systemsBrain Research.  708:38-44. 1996
    1996 Dopamine receptor mRNA expression in human striatum and neocortexNeuropsychopharmacology.  15:17-29. 1996
    1996 Frequency of neuropathology in a brain bank from a long-term, domiciliary populationJournal of Psychiatric Research.  30:45-49. 1996
    1995 Effects of cocaine on D3 and D4 receptor expression in the human striatumBiological Psychiatry.  38:263-266. 1995
    1995 The Human Dopamine D5 Receptor Gene: Cloning and Characterization of the 5′-Flanking and Promoter RegionBiochemistry.  34:5960-5970. 1995
    1995 Neocortical Abnormalities in SchizophreniaArchives of General Psychiatry.  52:819-820. 1995
    1994 Differential expression of autoreceptors in the ascending dopamine systems of the human brainProceedings of the National Academy of Sciences.  91:8297-8301. 1994
    1994 Ventricular enlargement, neuropsychological status, and premorbid function in schizophreniaBiological Psychiatry.  35:517-524. 1994
    1994 Dopamine receptor gene expression in the human medial temporal lobeNeuropsychopharmacology.  10:239-248. 1994
    1994 Human brain receptors, V: Binding and messageAmerican Journal of Psychiatry.  151:804. 1994
    1994 Prodynorphin-derived peptide expression in primate cortex and striatumNeuropeptides.  27:277-284. 1994
    1994 Update on dopamine receptorsAnnals of Clinical Psychiatry.  6:79-90. 1994
    1993 Effects of cocaine on dopamine receptor gene expression: A study in the postmortem human brainBiological Psychiatry.  34:348-355. 1993
    1993 Characterization of pro-opiomelanocortin processing in heterologous neuronal cells that express PC2 mRNANeuropeptides.  24:253-262. 1993
    1993 Expression of prodynorphin-derived peptides and mRNA in guinea-pig cortexNeuropeptides.  25:131-138. 1993
    1992 Distribution of D5 dopamine receptor mRNA in rat brainNeuroscience Letters.  145:209-212. 1992
    1992 Site-directed mutagenesis of the human dopamine D2 receptorEuropean Journal of Pharmacology.  227:205-214. 1992
    1992 A comparison of D1 receptor binding and mRNA in rat brain using receptor autoradiographic and in situ hybridization techniquesNeuroscience.  46:959-971. 1992
    1991 Comparison of the distributions of D1 and D2 dopamine receptor mRNAs in the rat brainNeuropsychopharmacology.  5:231-242. 1991
    1991 Expression of the dopamine D2 receptor gene in brainBiological Psychiatry.  30:985-1007. 1991
    1991 Dexamethasone suppression test in schizophrenia: Relationship to symptomatology, ventricular enlargement, and outcomeBiological Psychiatry.  29:953-964. 1991
    1991 Basal ganglia mineralization in schizophreniaBiological Psychiatry.  29:296-297. 1991
    1991 A comparison of D1 receptor binding and mRNA in rat brain using receptor autoradiographic and in situ hybridization techniquesNeuroscience.  45:359-371. 1991
    1991 Distribution of D2 dopamine receptor mRNA in the primate brainProgress in Neuro-Psychopharmacology and Biological Psychiatry.  15:885-893. 1991
    1991 Opiate Receptors: Opioid Agonist‐Antagonist EffectsPharmacotherapy: The Journal of Human Pharmacology and Drug Therapy.  11:164-167. 1991
    1990 Localization of dopamine D2 receptor mRNA and D1 and D2 receptor binding in the rat brain and pituitary: An in situ hybridization-receptor autoradiographic analysisJournal of Neuroscience.  10:2587-2600. 1990
    1990 Multiplicity of depressive episodes: Phenomenological and neuroendocrine correlatesBiological Psychiatry.  27:1156-1164. 1990
    1990 Differential effects of haloperidol on the rat pituitary: Decreased biosynthesis, processing and release of anterior lobe pro-opiomelanocortinNeuroendocrinology.  51:294-303. 1990
    1990 Psychiatric side effects of tricyclic antidepressantsHospital & community psychiatry.  41:84-86. 1990
    1990 Severity of depression and hypothalamic‐pituitary‐adrenal axis dysregulation: identification of contributing factorsActa Psychiatrica Scandinavica.  81:364-371. 1990
    1990 The effects of nigrostriatal 6-hydroxydopamine lesions on dopamine D2 receptor mRNA and opioid systems.Progress in clinical and biological research.  328:227-230. 1990
    1989 γ-melanotropin and β-endorphin after dexamethasoneBiological Psychiatry.  25:975-976. 1989
    1989 Positive and negative symptoms in schizophrenia and the dexamethasone suppression testBiological Psychiatry.  25:788-792. 1989
    1989 Distribution of D2 dopamine receptor mRNA in rat brainProceedings of the National Academy of Sciences.  86:7625-7628. 1989
    1988 Behavioral and cognitive toxicity related to elevated plasma tricyclic antidepressant levelsJournal of Clinical Psychopharmacology.  8:28-32. 1988
    1988 Dexamethasone suppression test status and severity of depressionBiological Psychiatry.  24:693-696. 1988
    1988 Doxepin-induced cardiac dysrhythmiaJournal of Clinical Psychopharmacology.  8:144-145. 1988
    1988 Effects of psychotropic medications on hypothalamic-pituitary-adrenal regulationEndocrinology and Metabolism Clinics of North America.  17:225-234. 1988
    1988 Effects of psychotropic medications on hypothalamic-pituitary-adrenal regulationEndocrinology and Metabolism Clinics of North America.  17:225-234. 1988
    1988 Plasma postdexamethasone cortisol levels in schizoaffective disorderPsychiatry Research.  26:35-42. 1988
    1988 Regional processing of the N- and C-terminal domains of proopiomelanocortin in monkey pituitary and brainNeuropeptides.  11:111-118. 1988
    1987 Gamma-melanotropin response to ovine corticotropin releasing factor in normal humansNeuropeptides.  9:269-282. 1987
    1987 Multiple depressive episodes and plasma postdexamethasone cortisol levelsBiological Psychiatry.  22:583-592. 1987
    1987 Postdexamethasone plasma cortisol and β-endorphin levels in depression: Relationship to severity of illnessBiological Psychiatry.  22:1137-1150. 1987
    1986 Gamma-3-MSH and beta-endorphin in monkey pituitary.NIDA research monograph.  75:307-310. 1986
    1986 Profound behavioral toxicity due to tricyclic antidepressantsJournal of Nervous and Mental Disease.  174:628-630. 1986
    1985 Differential proliferative responses of cultured Schwann cells to axolemma and myelin-enriched fractions. II. Morphological studiesJournal of Neurocytology.  14:619-635. 1985
    1984 Differential proliferative responses of cultured Schwann cells to axolemma- and myelin-enriched fractions. I. Biochemical studiesJournal of Cell Biology.  99:2309-2313. 1984
    1984 Cyclic AMP and calcium as potential mediators of stimulation of cultured Schwann cell proliferation by axolemma-enriched and myelin-enriched membrane fractionsBiochemical and Biophysical Research Communications.  122:373-380. 1984

    Book

    Year Title Altmetric
    2004 Schizophrenia as a disorder of neuroplasticity.  Ed. 59.  2004

    Chapter

    Year Title Altmetric
    2014 Evidence of glutamatergic dysfunction in the pathophysiology of schizophrenia.  265-294. 2014
    2008 A role for glutamate receptors, transporters, and interacting proteins in cortical dysfunction in schizophrenia.  113-147. 2008

    Research Overview

  • Dr. Meador-Woodruff's research has been continuously funded by NIH since 1989. His laboratory’s primary research interest is on understanding how different parts of the brain communicate with other parts via a variety of chemical signals, and how this communication is disrupted in schizophrenia. His current focus is on studying the expression of genes associated with glutamatergic neurotransmission within individual cells in the nervous system.
  • Teaching Overview

  • Dr. Meador-Woodruff has a longstanding interest in teaching and mentorship, and nearly 100 trainees have rotated through his lab. He was director of the University of Michigan’s Psychiatry Residency Research Track, and was the PI of one of the earliest NIMH R25 grants to fund such research exposure during residency training. He is the Editor-in-Chief of the journal Neuropsychopharmacology.
  • Education And Training

  • Doctor of Medicine in Psychiatry Residency Program, Virginia Commonwealth University 1984
  • Bachelor of Science or Mathematics in Chemistry, University of Richmond 1980
  • University of Michigan Hospitals & Health Centers, Internship 1985
  • University of Michigan Hospitals & Health Centers, Residency 1989
  • University of Michigan Hospitals & Health Centers, Postdoctoral Fellowship 1989
  • Full Name

  • James Meador-Woodruff