Positions

Selected Publications

Academic Article

Year Title Altmetric
2016 Gene-nutrient interaction markedly influences yeast chronological lifespanExperimental Gerontology.  86:113-123. 2016
2016 Ribosomal Stalk Protein Silencing Partially Corrects the ΔF508-CFTR Functional Expression DefectPLoS Biology.  14. 2016
2016 Long-range coupling between the extracellular gates and the intracellular ATP binding domains of multidrug resistance protein pumps and cystic fibrosis transmembrane conductance regulator channelsFederation proceedings.  30:1247-1262. 2016
2015 Yeast phenomics: An experimental approach for modeling gene interaction networks that buffer diseaseGenes.  6:24-45. 2015
2014 Aging and energetics' 'Top 40' future research opportunities 2010-2013F1000Research.  3. 2014
2014 Conserved allosteric hot spots in the transmembrane domains of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) channels and Multidrug Resistance Protein (MRP) pumpsJournal of Biological Chemistry.  289:19942-19957. 2014
2014 Phenomic assessment of genetic buffering by kinetic analysis of cell arraysMethods in Molecular Biology.  1205:187-208. 2014
2013 The SWI/SNF Chromatin Remodeling Complex Influences Transcription by RNA Polymerase I in Saccharomyces cerevisiaePLoS ONE.  8. 2013
2012 A yeast phenomic model for the gene interaction network modulating CFTR-ΔF508 protein biogenesisGenome Medicine.  4. 2012
2011 A screen to identify small molecule inhibitors of protein-protein interactions in mycobacteriaASSAY and Drug Development Technologies.  9:299-310. 2011
2010 Global analysis of phase locking in gene expression during cell cycle: The potential in network modelingBMC Systems Biology.  4. 2010
2010 Recursive expectation-maximization clustering: A method for identifying buffering mechanisms composed of phenomic modulesChaos.  20. 2010
2009 Genomewide analysis reveals novel pathways affecting endoplasmic eticulum homeostasis, protein modification and quality controlGenetics.  182:757-769. 2009
2009 Stringent mating-type-regulated auxotrophy increases the accuracy of systematic genetic interaction screens with Saccharomyces cerevisiae mutant arraysGenetics.  181:289-300. 2009
2008 Defining genetic interactionProceedings of the National Academy of Sciences.  105:3461-3466. 2008
2007 Buffering of deoxyribonucleotide pool homeostasis by threonine metabolismProceedings of the National Academy of Sciences.  104:11700-11705. 2007
2007 High throughput drug screening for human immunodeficiency virus type 1 reactivating compoundsASSAY and Drug Development Technologies.  5:181-189. 2007
2007 Accurate, precise modeling of cell proliferation kinetics from time-lapse imaging and automated image analysis of agar yeast culture arraysBMC Systems Biology.  1. 2007
2005 The case for strategic international alliances to harness nutritional genomics for public and personal healthBritish Journal of Nutrition.  94:623-632. 2005
2005 The case for strategic international alliances to harness nutritional genomics for public and personal healthBritish Journal of Nutrition.  94:623-632. 2005
2004 Systematic quantification of gene interactions by phenotypic array analysis.Genome Biology.  5. 2004
2001 Cell Biology: Principles for the buffering of genetic variationScience.  291:1001-1004. 2001
1996 Functional reconstitution in situ of 5-hydroxytryptamine(2c) (5HT(2c)) receptors with α(q) and inverse agonism of 5HT(2c) receptor antagonistsJournal of Biological Chemistry.  271:22591-22597. 1996
1994 Cystic fibrosis transmembrane conductance regulator mutations that disrupt nucleotide bindingJournal of Clinical Investigation.  94:228-236. 1994
1992 Affinity purification of insoluble recombinant fusion proteins containing glutathione‐S‐transferaseBiotechnology and Bioengineering.  39:828-832. 1992
1992 Hypothyroidism in adults with sickle cell anemiaAmerican Journal of Medicine.  92:567-570. 1992
1992 Hypothyroidism in adults with sickle cell anemiaAmerican Journal of Medicine.  92:567-570. 1992
1992 Intrinsic anion channel activity of the recombinant first nucleotide binding fold domain of the cystic fibrosis transmembrane regulator proteinProceedings of the National Academy of Sciences.  89:1539-1543. 1992
1992 Recombinant synthesis, purification, and nucleotide binding characteristics of the first nucleotide binding domain of the cystic fibrosis gene productJournal of Biological Chemistry.  267:6455-6458. 1992
1990 Regulation of Tissue Plasminogen Activator in Sickle Cell AnemiaAmerican Journal of Hematology.  35:167-170. 1990
1988 Totally implantable intravenous catheters in the management of sickle cell anemiaAmerican Journal of Hematology.  29:134-138. 1988
1988 Chronic granulocytic leukemia in a patient with sickle cell anemiaAmerican Journal of Medicine.  85:567-569. 1988
Nutritional Genomics: Discovering the Path to Personalized Nutrition

Chapter

Year Title Altmetric
2006 Genetic and Molecular Buffering of Phenotypes.  105-134. 2006

Education And Training

  • Doctor of Medicine, University of Alabama at Birmingham 1995
  • Bachelor of Science or Mathematics in Zoological Medicine Residency Program, Duke University 1989
  • Full Name

  • John Hartman