Positions

Selected Publications

Academic Article

Year Title Altmetric
2017 Bimodal regulation of Dishevelled function by Vangl2 during morphogenesisHuman Molecular Genetics.  26:2053-2061. 2017
2016 Sema6D acts downstream of bone morphogenetic protein signalling to promote atrioventricular cushion development in miceCardiovascular Research.  112:532-542. 2016
2016 Spatial regulation of cell cohesion by Wnt5a during second heart field progenitor deploymentDevelopmental Biology.  412:18-31. 2016
2015 Mapping the dynamic expression of Wnt11 and the lineage contribution of Wnt11-expressing cells during early mouse developmentDevelopmental Biology.  398:177-192. 2015
2015 Loss of Wnt5a disrupts second heart field cell deployment and may contribute to OFT malformations in DiGeorge syndromeHuman Molecular Genetics.  24:1704-1716. 2015
2012 Disheveled mediated planar cell polarity signaling is required in the second heart field lineage for outflow tract morphogenesisDevelopmental Biology.  370:135-144. 2012
2012 Wnt signaling in mammalian development: Lessons from mouse geneticsCold Spring Harbor perspectives in biology.  4:6. 2012
2011 Disruption of PCP signaling causes limb morphogenesis and skeletal defects and may underlie Robinow syndrome and brachydactyly type BHuman Molecular Genetics.  20:271-285. 2011
2010 Planar polarization of node cells determines the rotational axis of node ciliaNature Cell Biology.  12:170-176. 2010
2008 Murine Dishevelled 3 Functions in Redundant Pathways with Dishevelled 1 and 2 in Normal Cardiac Outflow Tract, Cochlea, and Neural Tube DevelopmentPLoS Genetics.  4:e1000259-e1000259. 2008
2007 Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functionsDevelopment.  135:367-375. 2007
2006 Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulationDevelopment.  133:1767-1778. 2006
2005 Regulation of polarized extension and planar cell polarity in the cochlea by the vertebrate PCP pathwayNature Genetics.  37:980-985. 2005
2004 The canonical Wnt pathway in early mammalian embryogenesis and stem cell maintenance/differentiationCurrent Opinion in Genetics and Development.  14:533-539. 2004
2002 Dishevelled 2 is essential for cardiac outflow tract development, somite segmentation and neural tube closureDevelopment.  129:5827-5838. 2002
2002 Identification of a Wnt/Dvl/β-Catenin → Pitx2 Pathway Mediating Cell-Type-Specific Proliferation during DevelopmentCell.  111:673-685. 2002
2002 The mouse PcG gene eed is required for Hox gene repression and extraembryonic developmentMammalian Genome.  13:493-503. 2002
2002 Regulation of AChR clustering by Dishevelled interacting with MuSK and PAK1.Neuron.  35:489-505. 2002
2001 Imprinted X inactivation maintained by a mouse Polycomb group geneNature Genetics.  28:371-375. 2001
2000 Mouse homolog of the Drosophila Pc-G gene esc exerts a dominant negative effect in DrosophilaDevelopmental Genetics.  26:67-67. 2000

Education And Training

  • Doctor of Philosophy in Genetics, Case Western Reserve University 2001
  • Bachelor of Science or Mathematics in Cell Biology and Anatomy, 1992
  • Full Name

  • Jianbo Wang