Positions

Selected Publications

Academic Article

Year Title Altmetric
2019 Cardiomyocyte Homeodomain-Interacting Protein Kinase 2 Maintains Basal Cardiac Function via Extracellular Signal-Regulated Kinase SignalingCirculation.  140:1820-1833. 2019
2019 Cadherin-11 blockade reduces inflammation-driven fibrotic remodeling and improves outcomes after myocardial infarctionJCI insight.  4. 2019
2019 Cardiomyocyte-GSK-3α promotes mPTP opening and heart failure in mice with chronic pressure overloadJournal of Molecular and Cellular Cardiology.  130:65-75. 2019
2019 Ponatinib-induced cardiotoxicity: Delineating the signalling mechanisms and potential rescue strategiesCardiovascular Research.  115:966-977. 2019
2019 Cardiomyocyte SMAD4-Dependent TGF-β Signaling is Essential to Maintain Adult Heart HomeostasisJACC: Basic to Translational Science.  4:41-53. 2019
2019 Generation of Nppa-tagBFP reporter knock-in mouse line for studying cardiac chamber specificationDevelopmental Genetics2019
2019 IL-10–producing B cells are enriched in murine pericardial adipose tissues and ameliorate the outcome of acute myocardial infarctionProceedings of the National Academy of Sciences.  116:21673-21684. 2019
2019 Inhibition of GSK-3 to induce cardiomyocyte proliferation: a recipe for in situ cardiac regenerationCardiovascular Research.  115:20-30. 2019
2018 Cardiomyocyte-specific deletion of GSK-3β leads to cardiac dysfunction in a diet induced obesity modelInternational Journal of Cardiology.  259:145-152. 2018
2017 Chronic Neuregulin-1β Treatment Mitigates the Progression of Postmyocardial Infarction Heart Failure in the Setting of Type 1 Diabetes Mellitus by Suppressing Myocardial Apoptosis, Fibrosis, and Key Oxidant-Producing EnzymesJournal of Cardiac Failure.  23:887-899. 2017
2017 Entanglement of GSK-3β, β-catenin and TGF-β1 signaling network to regulate myocardial fibrosisJournal of Molecular and Cellular Cardiology.  110:109-120. 2017
2017 Mechanistic Insights of Empagliflozin-Mediated Cardiac Benefits: Nearing the Starting Line: Editorial to: “Empagliflozin Improves Left Ventricular Diastolic Dysfunction in a Genetic Model of Type 2 Diabetes” by N. Hammoudi et al.Cardiovascular Drugs and Therapy.  31:229-232. 2017
2017 Activation of the amino acid response pathway blunts the effects of cardiac stressJournal of the American Heart Association : Cardiovascular and Cerebrovascular Disease.  6. 2017
2016 Response by Zhou et al to Letter Regarding Article, Loss of Adult Cardiac Myocyte GSK-3 Leads to Mitotic Catastrophe Resulting in Fatal Dilated CardiomyopathyCirculation Research.  119:e29-e30. 2016
2016 Loss of adult cardiac myocyte GSK-3 leads to mitotic catastrophe resulting in fatal dilated cardiomyopathyCirculation Research.  118:1208-1222. 2016
2015 The GSK-3 family as therapeutic target for myocardial diseasesCirculation Research.  116:138-149. 2015
2014 Cardiomyocyte-specific deletion of Gsk3α mitigates post-myocardial infarction remodeling, contractile dysfunction, and heart failureJournal of the American College of Cardiology.  64:696-706. 2014
2014 Cardiac fibroblast glycogen synthase kinase-3β regulates ventricular remodeling and dysfunction in ischemic heartCirculation.  130:419-430. 2014
2014 Sorafenib cardiotoxicity increases mortality after myocardial infarctionCirculation Research.  114:1700-1712. 2014
2014 Prevention of liver cancer cachexia-induced cardiac wasting and heart failureEuropean Heart Journal.  35:932-941. 2014
2014 Troponin I-interacting protein kinase - A novel cardiac-specific kinase, emerging as a molecular target for the treatment of cardiac diseaseCirculation Journal.  78:1514-1519. 2014
2013 Anthrax lethal toxin induces acute diastolic dysfunction in rats through disruption of the phospholamban signaling networkInternational Journal of Cardiology.  168:3884-3895. 2013
2013 Caveolin and β1-integrin coordinate angiotensinogen expression in cardiac myocytesInternational Journal of Cardiology.  168:436-445. 2013
2013 GSK-3α is a central regulator of age-related pathologies in miceJournal of Clinical Investigation.  123:1821-1832. 2013
2013 Cancer genetics and the cardiotoxicity of the therapeuticsJournal of the American College of Cardiology.  61:267-274. 2013
2012 Glycogen synthase kinase-3α limits ischemic injury, cardiac rupture, post-myocardial infarction remodeling and deathCirculation.  125:65-75. 2012
2011 Rac1 and RhoA differentially regulate angiotensinogen gene expression in stretched cardiac fibroblastsCardiovascular Research.  90:88-96. 2011
2011 A novel cardioprotective p38-MAPK/mTOR pathwayExperimental Cell Research.  317:2938-2949. 2011
2010 GSK-3α directly regulates β-adrenergic signaling and the response of the heart to hemodynamic stress in miceJournal of Clinical Investigation.  120:2280-2291. 2010
2010 Glycogen synthase kinase-3β regulates post-myocardial infarction remodeling and stress-induced cardiomyocyte proliferation in vivoCirculation Research.  106:1635-1645. 2010
2009 Anthrax toxin: Pathologic effects on the cardiovascular systemFrontiers in Bioscience.  14:2335-2357. 2009
2009 Integrins and proximal signaling mechanisms in cardiovascular diseaseFrontiers in Bioscience.  14:2307-2334. 2009
2008 Stretch-induced regulation of angiotensinogen gene expression in cardiac myocytes and fibroblasts: Opposing roles of JNK1/2 and p38α MAP kinasesJournal of Molecular and Cellular Cardiology.  45:770-778. 2008
2007 Stretch-induced MAP kinase activation in cardiac myocytes: Differential regulation through β1-integrin and focal adhesion kinaseJournal of Molecular and Cellular Cardiology.  43:137-147. 2007
2007 Lethal and edema toxins of anthrax induce distinct hemodynamic dysfunctionFrontiers in Bioscience.  12:4670-4675. 2007
2007 Integrins: Novel therapeutic targets for cardiovascular diseasesCardiovascular and Hematological Agents in Medicinal Chemistry.  5:109-132. 2007
2000 Stress induced phosphate solubilization in bacteria isolated from alkaline soilsFEMS Microbiology Letters.  182:291-296. 2000

Chapter

Year Title Altmetric
2009 Molecular Signaling Mechanisms of Myocardial Stretch: Implications for Heart Disease 2009

Education And Training

  • Doctor of Philosophy in Microbiology, 2006
  • Full Name

  • Hind Lal
  • Blazerid

  • hindlal