Positions

Selected Publications

Academic Article

Year Title Altmetric
2019 Genome-Wide Profiling of Cervical RNA-Binding Proteins Identifies Human Papillomavirus Regulation of RNASEH2A Expression by Viral E7 and E2F1mBio.  10. 2019
2018 Vorinostat, a pan-HDAC inhibitor, abrogates productive HPV-18 DNA amplificationProceedings of the National Academy of Sciences.  115:E11138-E11147. 2018
2017 Role of remodeling and spacing factor 1 in histone H2A ubiquitination-mediated gene silencingProceedings of the National Academy of Sciences.  114:E7949-E7958. 2017
2017 Efficient, ultra-high-Affinity chromatography in a one-step purification of complex proteinsProceedings of the National Academy of Sciences.  114:E5138-E5147. 2017
2016 The histone H2A deubiquitinase Usp16 regulates hematopoiesis and hematopoietic stem cell functionProceedings of the National Academy of Sciences.  113:E51-E60. 2016
2015 Cross-talk between PRMT1-mediated methylation and ubiquitylation on RBM15 controls RNA splicingeLife.  4. 2015
2015 In vitro and in vivo assays for studying histone ubiquitination and deubiquitination 2015
2015 Snail2/slug cooperates with polycomb repressive complex 2 (Prc2) to regulate neural crest developmentDevelopment.  142:722-731. 2015
2014 The histone H2A deubiquitinase USP16 interacts with HERC2 and fine-tunes cellular response to DNA damageJournal of Biological Chemistry.  289:32883-32894. 2014
2014 HDAC6 deacetylates and ubiquitinates MSH2 to maintain proper levels of MutSαMolecular Cell.  55:31-46. 2014
2014 The histone H2A deubiquitinase Usp16 regulates embryonic stem cell gene expression and lineage commitmentNature Communications.  5. 2014
2014 Sp7 and Runx2 molecular complex synergistically regulate expression of target genesConnective Tissue Research.  55:83-87. 2014
2013 USP49 deubiquitinates histone H2B and regulates cotranscriptional pre-mRNA splicingGenes and Development.  27:1581-1595. 2013
2013 Ubp-M serine 552 phosphorylation by cyclin-dependent kinase 1 regulates cell cycle progressionCell Cycle.  12:3219-3227. 2013
2011 Purification of histone ubiquitin ligases from HeLa cellsMethods.  54:315-325. 2011
2011 Regulation of histone H2A and H2B deubiquitination and xenopus development by USP12 and USP46Journal of Biological Chemistry.  286:7190-7201. 2011
2011 PRC2 complexes with JARID2, MTF2, and esPRC2p48 in ES cells to modulate ES cell pluripotency and somatic cell reprogramingSTEM CELLS.  29:229-240. 2011
2010 Polycomb repressive complex 2 in embryonic stem cells: An overviewProtein and Cell.  1:1056-1062. 2010
2009 Regulation of Set9-Mediated H4K20 Methylation by a PWWP Domain ProteinMolecular Cell.  33:428-437. 2009
2009 In vitro and in vivo assays for studying histone ubiquitination and deubiquitination.Methods in Molecular Biology.  523:295-309. 2009
2008 Role of hPHF1 in H3K27 methylation and Hox gene silencingMolecular and Cellular Biology.  28:1862-1872. 2008
2008 PRDM6 is enriched in vascular precursors during development and inhibits endothelial cell proliferation, survival, and differentiationJournal of Molecular and Cellular Cardiology.  44:47-58. 2008
2007 Regulation of cell cycle progression and gene expression by H2A deubiquitinationNature.  449:1068-1072. 2007
2006 Role of Bmi1 in H2A ubiquitylation and Hox gene silencingJournal of Biological Chemistry.  281:22537-22544. 2006
2006 "Cullin 4 makes its mark on chromatin".Cell Division.  1:14. 2006
2006 Histone H3 and H4 Ubiquitylation by the CUL4-DDB-ROC1 Ubiquitin Ligase Facilitates Cellular Response to DNA DamageMolecular Cell.  22:383-394. 2006
2004 Role of histone H2A ubiquitination in Polycomb silencingNature.  431:873-878. 2004
2003 mAM Facilitates Conversion by ESET of Dimethyl to Trimethyl Lysine 9 of Histone H3 to Cause Transcriptional RepressionMolecular Cell.  12:475-487. 2003
2003 Role of Histone H3 Lysine 27 Methylation in X InactivationScience.  300:131-135. 2003
2002 Role of Histone H3 Lysine 27 Methylation in Polycomb-Group SilencingScience.  298:1039-1043. 2002
2002 Purification and Functional Characterization of SET8, a Nucleosomal Histone H4-Lysine 20-Specific MethyltransferaseCurrent Biology.  12:1086-1099. 2002
2002 Molecular cloning of ESET, a novel histone H3-specific methyltransferase that interacts with ERG transcription factorOncogene.  21:148-152. 2002
2001 Purification and Functional Characterization of a Histone H3-Lysine 4-Specific MethyltransferaseMolecular Cell.  8:1207-1217. 2001
2001 Methylation of Histone H4 at Arginine 3 Facilitating Transcriptional Activation by Nuclear Hormone ReceptorScience.  293:853-857. 2001
2001 Mi2, an auto-antigen for dermatomyositis, is an ATP-dependent nucleosome remodeling factorNucleic Acids Research.  29:2517-2521. 2001
1997 In vitro experimental systems for HPV: Epithelial raft cultures for investigations of viral reproduction and pathogenesis and for genetic analyses of viral proteins and regulatory sequencesClinics in Dermatology.  15:217-227. 1997
1996 Transition of human papillomavirus type 16 and 18 transfected human foreskin keratinocytes towards immortality: Activation of telomerase and allele losses at 3p, 10p, 11q and/or 18qOncogene.  13:1249-1257. 1996
1994 Structure and expression of the human gene for the α subunit of prolyl 4- hydroxylase. The two alternatively spliced types of mRNA correspond to two homologous exons the sequences of which are expressed in a variety of tissuesJournal of Biological Chemistry.  269:27847-27854. 1994
1992 Viral E1 and E2 proteins support replication of homologous and heterologous papillomaviral originsProceedings of the National Academy of Sciences.  89:5799-5803. 1992
1992 Control of human papillomavirus type 11 origin of replication by the E2 family of transcription regulatory proteinsJournal of Virology.  66:5224-5231. 1992
1992 Epithelial-specific gene expression during differentiation of stratified primary human keratinocyte cultures.Cell Growth and Differentiation.  3:471-483. 1992
1992 Intermolecular triplex formation distorts the DNA duplex in the regulatory region of human papillomavirus type-11Journal of Biological Chemistry.  267:5488-5494. 1992
1992 Structure of the human 70 K type IV collagenase gene and assignment of the gene to the q21 region of chromosome 16.Matrix (Stuttgart, Germany). Supplement.  1:84. 1992
1991 Complete structure of the human gene for 92-kDa type IV collagenase. Divergent regulation of expression for the 92- and 72-kilodalton enzyme genes in HT-1080 cellsJournal of Biological Chemistry.  266:16485-16490. 1991
1991 Structure of the human laminin B2 chain gene reveals extensive divergence from the laminin B1 chain geneJournal of Biological Chemistry.  266:221-228. 1991
1991 Characterization of the 3′ half of the human type IV collagen α5 gene that is affected in the Alport syndromeGenomics.  9:1-9. 1991
1990 Structure and expression of type IV collagenase genesCell differentiation and development : the official journal of the International Society of Developmental Biologists.  32:307-312. 1990
1990 Structure of the human laminin B1 chain geneJournal of Biological Chemistry.  265:15611-15616. 1990
1990 Structure of the human type IV collagenase geneJournal of Biological Chemistry.  265:11077-11082. 1990
1990 Characterization of cDNA and Genomic Clones for the α Subunit of Human Prolyl 4‐HydroxylaseAnnals of the New York Academy of Sciences.  580:473-476. 1990
1990 Identification of mutations in the COL4A5 collagen gene in Alport syndromeScience.  248:1224-1227. 1990
1988 Characterization of the human gene for a polypeptide that acts both as the β subunit of prolyl 4-hydroxylase and as protein disulfide isomeraseJournal of Biological Chemistry.  263:16218-16224. 1988
1987 Genetic relationship among human papillomaviruses associated with benign and malignant tumours of patients with epidermodysplasia verruciformisJournal of General Virology.  68:3091-3103. 1987
1986 The gene for the alpha 1(IV) chain of human type IV procollagen: the exon structures do not coincide with the two structural subdomains in the globular carboxy-terminus of the protein.EMBO Journal.  5:2821-2823. 1986
1986 Large introns in the 3' end of the gene for the proα1(IV) chain of human basement membrane collagenProceedings of the National Academy of Sciences.  83:1568-1572. 1986
1985 Characterization of 64-, 123- and 182-base-pair exons in the mouse α2(IV) collagen geneNature.  317:177-179. 1985

Chapter

Year Title Altmetric
2013 Ubiquitin Specific Peptidase 16.  2090-2094. 2013

Education And Training

  • Doctorate Level Degree in Plant Sciences, China Agricultural University 1997
  • Full Name

  • Hengbin Wang