Selected Publications

Academic Article

Year Title Altmetric
2019 Obesogenic diet in aging mice disrupts gut microbe composition and alters neutrophil:lymphocyte ratio, leading to inflamed milieu in acute heart failure 2019
2019 Immune responsive resolvin D1 programs peritoneal macrophages and cardiac fibroblast phenotypes in diversified metabolic microenvironment 2019
2019 Mitoquinone ameliorates pressure overload-induced cardiac fibrosis and left ventricular dysfunction in mice 2019
2019 Pretreatment of carprofen impaired initiation of inflammatory- and overlapping resolution response and promoted cardiorenal syndrome in heart failure 2019
2018 Subacute treatment of carprofen facilitate splenocardiac resolution deficit in cardiac injury 2018
2018 The failing of the obesity paradox in the failing heart 2018
2018 Cancer Therapy-Induced Cardiovascular Toxicity: Doxorubicin triggers splenic contraction and irreversible dysregulation of cox and lox that alters the inflammation-resolution program in the myocardium 2018
2018 Unified nexus of macrophages and maresins in cardiac reparative mechanisms 2018
2018 The mouse heart attack research tool 1.0 database 2018
2018 Immune responsive resolvin D1 programs myocardial infarction–induced cardiorenal syndrome in heart failure 2018
2018 Paradigm shift – Metabolic transformation of docosahexaenoic and eicosapentaenoic acids to bioactives exemplify the promise of fatty acid drug discovery 2018
2018 Genetic deletion of 12/15 lipoxygenase promotes effective resolution of inflammation following myocardial infarction 2018
2018 Splenic leukocytes define the resolution of inflammation in heart failure 2018
2018 Comprehensive targeted and non-targeted lipidomics analyses in failing and non-failing heart 2018
2018 Excess ω-6 fatty acids influx in aging drives metabolic dysregulation, electrocardiographic alterations, and low-grade chronic inflammation 2018
2018 Heart functional and structural compendium of cardiosplenic and cardiorenal networks in acute and chronic heart failure pathology 2018
2018 Nox2 activity is required in obesity-mediated alteration of bone remodeling 2018
2017 Glucose transporter 4-deficient hearts develop maladaptive hypertrophy in response to physiological or pathological stresses 2017
2017 Resolution Agonist 15-epi-Lipoxin A 4 Programs Early Activation of Resolving Phase in Post-Myocardial Infarction Healing 2017
2017 Obesity and Cardiometabolic Defects in Heart Failure Pathology. 2017
2017 Interaction of 12/15-lipoxygenase with fatty acids alters the leukocyte kinetics leading to improved postmyocardial infarction healing 2017
2017 Metabolic and Biochemical Stressors in Diabetic Cardiomyopathy. 2017
2016 Neutrophils: Friend, foe, or contextual ally in myocardial healing 2016
2016 Abrogation of Nrf2 impairs antioxidant signaling and promotes atrial hypertrophy in response to high-intensity exercise stress 2016
2016 Myocardial infarction superimposed on aging: MMP-9 deletion promotes M2 macrophage polarization 2016
2016 CD36 Is a Matrix Metalloproteinase-9 Substrate That Stimulates Neutrophil Apoptosis and Removal during Cardiac Remodeling 2016
2016 Aging dysregulates D- and E-series resolvins to modulate cardiosplenic and cardiorenal network following myocardial infarction 2016
2015 Big eater macrophages dominate inflammation resolution following myocardial infarction 2015
2015 Building a better infarct: Modulation of collagen cross-linking to increase infarct stiffness and reduce left ventricular dilation post-myocardial infarction 2015
2015 Resolvin D1 activates the inflammation resolving response at splenic and ventricular site following myocardial infarction leading to improved ventricular function 2015
2015 Nox2 mediates skeletal muscle insulin resistance induced by a high fat diet 2015
2015 Cardiomyocyte-specific Bmal1 deletion in mice triggers diastolic dysfunction, extracellular matrix response, and impaired resolution of inflammation 2015
2015 Obesity superimposed on aging magnifies inflammation and delays the resolving response after myocardial infarction 2015
2014 Citrate synthase is a novel in vivo matrix metalloproteinase-9 substrate that regulates mitochondrial function in the postmyocardial infarction left ventricle 2014
2014 Caveolin-1 deletion exacerbates cardiac interstitial fibrosis by promoting M2 macrophage activation in mice after myocardial infarction 2014
2014 Aging and energetics' 'Top 40' future research opportunities 2010-2013 2014
2014 Cardiac extracellular proteome profiling and membrane topology analysis using glycoproteomics 2014
2014 Inflammation revisited: inflammation versus resolution of inflammation following myocardial infarction 2014
2014 Streptococcus pneumoniae Translocates into the Myocardium and Forms Unique Microlesions That Disrupt Cardiac Function 2014
2013 Reduced BDNF attenuates inflammation and angiogenesis to improve survival and cardiac function following myocardial infarction in mice 2013
2013 Matrix metalloproteinase (MMP)-9: A proximal biomarker for cardiac remodeling and a distal biomarker for inflammation 2013
2013 Texas 3-Step decellularization protocol: Looking at the cardiac extracellular matrix 2013
2013 Concentrated fish oil (Lovaza®) extends lifespan and attenuates kidney disease in lupus-prone short-lived (NZBxNZW)F1 mice 2013
2013 Matrix metalloproteinase-28 deletion exacerbates cardiac dysfunction and rupture after myocardial infarction in mice by inhibiting M2 macrophage activation 2013
2013 Cardiac wound healing post-myocardial infarction: A novel method to target extracellular matrix remodeling in the left ventricle 2013
2013 Cardiac wound healing post-myocardial infarction: A novel method to target extracellular matrix remodeling in the left ventricle 2013
2013 Obese and diabetic KKAy mice show increased mortality but improved cardiac function following myocardial infarction 2013
2012 Extracellular matrix and fibroblast communication following myocardial infarction 2012
2012 Transgenic overexpression of matrix metalloproteinase-9 in macrophages attenuates the inflammatory response and improves left ventricular function post-myocardial infarction 2012
2012 DHA derivatives of fish oil as dietary supplements: A nutrition-based drug discovery approach for therapies to prevent metabolic cardiotoxicity 2012
2012 Mathematical modeling and stability analysis of macrophage activation in left ventricular remodeling post-myocardial infarction. 2012
2012 Roles of saturated vs. polyunsaturated fat in heart failure survival: Not all fats are created equal 2012
2011 t10c12-CLA maintains higher bone mineral density during aging by modulating osteoclastogenesis and bone marrow adiposity 2011
2011 Combination of conjugated linoleic acid with fish oil prevents age-associated bone marrow adiposity in C57Bl/6J mice 2011
2011 Fish oil decreases inflammation and reduces cardiac remodeling in rosiglitazone treated aging mice 2011
2011 Obesity-mediated inflammatory microenvironment stimulates osteoclastogenesis and bone loss in mice 2011
2010 High fat diet-induced animal model of age-associated obesity and osteoporosis 2010
2010 Docosahexaenoic acid-enriched fish oil attenuates kidney disease and prolongs median and maximal life span of autoimmune lupus-prone mice 2010
2010 Differential effects of conjugated linoleic acid isomers in insulin-resistant female C57Bl/6J mice 2010
2009 The fat-1 transgene in mice increases antioxidant potential, reduces pro-inflammatory cytokine levels, and enhances PPA Rγ and SIRT-1 expression on a calorie restricted diet 2009
2009 Conjugated linoleic acid (CLA) prevents age-associated skeletal muscle loss 2009
2009 Effect of CLA isomers and their mixture on aging C57Bl/6J mice 2009
2006 Hypoglycemic activity of Cassia auriculata in neonatal streptozotocin-induced non-insulin dependent diabetes mellitus in rats 2006


Year Title Altmetric
2013 Extracellular matrix biomarkers of adverse remodeling after myocardial infarction.  383-412. 2013

Full Name

  • Ganesh Halade