Positions

Selected Publications

Academic Article

Year Title Altmetric
2019 Immune responsive resolvin D1 programs peritoneal macrophages and cardiac fibroblast phenotypes in diversified metabolic microenvironment.Journal of Cellular Physiology.  234:3910-3920. 2019
2018 Subacute treatment of carprofen facilitate splenocardiac resolution deficit in cardiac injury.Journal of Leukocyte Biology.  104:1173-1186. 2018
2018 Doxorubicin triggers splenic contraction and irreversible dysregulation of COX and LOX that alters the inflammation-resolution program in the myocardium.AJP - Heart and Circulatory Physiology.  315:H1091-H1100. 2018
2018 Unified nexus of macrophages and maresins in cardiac reparative mechanisms.Federation proceedings.  32:5227-5237. 2018
2018 The Mouse Heart Attack Research Tool 1.0 database.AJP - Heart and Circulatory Physiology.  315:H522-H530. 2018
2018 The failing of the obesity paradox in the failing heart.AJP - Heart and Circulatory Physiology2018
2018 Immune responsive resolvin D1 programs myocardial infarction-induced cardiorenal syndrome in heart failure.Federation proceedings.  32:3717-3729. 2018
2018 Paradigm shift - Metabolic transformation of docosahexaenoic and eicosapentaenoic acids to bioactives exemplify the promise of fatty acid drug discovery.Biotechnology Advances.  36:935-953. 2018
2018 Genetic deletion of 12/15 lipoxygenase promotes effective resolution of inflammation following myocardial infarction.Journal of Molecular and Cellular Cardiology.  118:70-80. 2018
2018 Splenic leukocytes define the resolution of inflammation in heart failure.Science Signaling.  11. 2018
2018 Comprehensive targeted and non-targeted lipidomics analyses in failing and non-failing heart.Fresenius' Journal of Analytical Chemistry.  410:1965-1976. 2018
2017 Glucose transporter 4-deficient hearts develop maladaptive hypertrophy in response to physiological or pathological stresses.AJP - Heart and Circulatory Physiology.  313:H1098-H1108. 2017
2017 Heart functional and structural compendium of cardiosplenic and cardiorenal networks in acute and chronic heart failure pathology.AJP - Heart and Circulatory Physiology.  314:H255-H267. 2017
2017 Excess ω-6 fatty acids influx in aging drives metabolic dysregulation, electrocardiographic alterations, and low-grade chronic inflammation.AJP - Heart and Circulatory Physiology.  314:H160-H169. 2017
2017 Obesity and Cardiometabolic Defects in Heart Failure Pathology.Comprehensive Physiology.  7:1463-1477. 2017
2017 Resolution Agonist 15-epi-Lipoxin A4 Programs Early Activation of Resolving Phase in Post-Myocardial Infarction Healing.Scientific Reports.  7:9999. 2017
2017 Interaction of 12/15-lipoxygenase with fatty acids alters the leukocyte kinetics leading to improved postmyocardial infarction healing.AJP - Heart and Circulatory Physiology.  313:H89-H102. 2017
2017 Metabolic and Biochemical Stressors in Diabetic Cardiomyopathy.Frontiers in Cardiovascular Medicine.  4:31. 2017
2016 Aging dysregulates D- and E-series resolvins to modulate cardiosplenic and cardiorenal network following myocardial infarction.Aging.  8:2611-2634. 2016
2016 Neutrophils: Friend, foe, or contextual ally in myocardial healing.Journal of Molecular and Cellular Cardiology.  97:44-46. 2016
2016 Abrogation of Nrf2 impairs antioxidant signaling and promotes atrial hypertrophy in response to high-intensity exercise stress.Journal of Translational Medicine.  14:86. 2016
2016 Myocardial Infarction Superimposed on Aging: MMP-9 Deletion Promotes M2 Macrophage Polarization.Journals of Gerontology, Series A.  71:475-483. 2016
2016 CD36 Is a Matrix Metalloproteinase-9 Substrate That Stimulates Neutrophil Apoptosis and Removal During Cardiac Remodeling.Circulation: Cardiovascular Genetics.  9:14-25. 2016
2015 Cardiomyocyte-specific Bmal1 deletion in mice triggers diastolic dysfunction, extracellular matrix response, and impaired resolution of inflammation.AJP - Heart and Circulatory Physiology.  309:H1827-H1836. 2015
2015 Big eater macrophages dominate inflammation resolution following myocardial infarction.Journal of Molecular and Cellular Cardiology.  87:225-227. 2015
2015 Building a better infarct: Modulation of collagen cross-linking to increase infarct stiffness and reduce left ventricular dilation post-myocardial infarction.Journal of Molecular and Cellular Cardiology.  85:229-239. 2015
2015 Resolvin D1 activates the inflammation resolving response at splenic and ventricular site following myocardial infarction leading to improved ventricular function.Journal of Molecular and Cellular Cardiology.  84:24-35. 2015
2015 Nox2 mediates skeletal muscle insulin resistance induced by a high fat diet.Journal of Biological Chemistry.  290:13427-13439. 2015
2015 Obesity superimposed on aging magnifies inflammation and delays the resolving response after myocardial infarction.AJP - Heart and Circulatory Physiology.  308:H269-H280. 2015
2014 Citrate synthase is a novel in vivo matrix metalloproteinase-9 substrate that regulates mitochondrial function in the postmyocardial infarction left ventricle.Antioxidants and Redox Signaling.  21:1974-1985. 2014
2014 Caveolin-1 deletion exacerbates cardiac interstitial fibrosis by promoting M2 macrophage activation in mice after myocardial infarction.Journal of Molecular and Cellular Cardiology.  76:84-93. 2014
2014 Streptococcus pneumoniae translocates into the myocardium and forms unique microlesions that disrupt cardiac function.PLoS Pathogens.  10:e1004383. 2014
2014 Cardiac extracellular proteome profiling and membrane topology analysis using glycoproteomics.PROTEOMICS - Clinical Applications.  8:595-602. 2014
2014 Aging and energetics' 'Top 40' future research opportunities 2010-2013.F1000Research.  3:219. 2014
2014 Inflammation revisited: inflammation versus resolution of inflammation following myocardial infarction.Basic Research in Cardiology.  109:444. 2014
2013 Reduced BDNF attenuates inflammation and angiogenesis to improve survival and cardiac function following myocardial infarction in mice.AJP - Heart and Circulatory Physiology.  305:H1830-H1842. 2013
2013 Obese and diabetic KKAy mice show increased mortality but improved cardiac function following myocardial infarction.Cardiovascular Pathology.  22:481-487. 2013
2013 Matrix metalloproteinase (MMP)-9: a proximal biomarker for cardiac remodeling and a distal biomarker for inflammation.Pharmacology and Therapeutics.  139:32-40. 2013
2013 Texas 3-step decellularization protocol: looking at the cardiac extracellular matrix.Journal of Biochemical and Biophysical Methods.  86:43-52. 2013
2013 Concentrated fish oil (Lovaza(R)) extends lifespan and attenuates kidney disease in lupus-prone short-lived (NZBxNZW)F1 mice.Proceedings of the Society for Experimental Biology and Medicine.  238:610-622. 2013
2013 Matrix metalloproteinase-28 deletion exacerbates cardiac dysfunction and rupture after myocardial infarction in mice by inhibiting M2 macrophage activation.Circulation Research.  112:675-688. 2013
2013 Cardiac wound healing post-myocardial infarction: A novel method to target extracellular matrix remodeling in the left ventricleMethods in Molecular Biology.  1037:313-324. 2013
2013 Cardiac wound healing post-myocardial infarction: a novel method to target extracellular matrix remodeling in the left ventricle.Methods in Molecular Biology.  1037:313-324. 2013
2012 Extracellular matrix and fibroblast communication following myocardial infarction.Journal of Cardiovascular Translational Research.  5:848-857. 2012
2012 Transgenic overexpression of matrix metalloproteinase-9 in macrophages attenuates the inflammatory response and improves left ventricular function post-myocardial infarction.Journal of Molecular and Cellular Cardiology.  53:599-608. 2012
2012 DHA derivatives of fish oil as dietary supplements: a nutrition-based drug discovery approach for therapies to prevent metabolic cardiotoxicity.Expert Opinion on Drug Discovery.  7:711-721. 2012
2012 Mathematical modeling and stability analysis of macrophage activation in left ventricular remodeling post-myocardial infarction.BMC Genomics.  13 Suppl 6:S21. 2012
2012 Roles of saturated vs. polyunsaturated fat in heart failure survival: not all fats are created equal.Cardiovascular Research.  93:4-5. 2012
2011 t10c12-CLA maintains higher bone mineral density during aging by modulating osteoclastogenesis and bone marrow adiposity.Journal of Cellular Physiology.  226:2406-2414. 2011
2011 Combination of conjugated linoleic acid with fish oil prevents age-associated bone marrow adiposity in C57Bl/6J mice.Journal of Nutritional Biochemistry.  22:459-469. 2011
2011 Fish oil decreases inflammation and reduces cardiac remodeling in rosiglitazone treated aging mice.Pharmacological Research.  63:300-307. 2011
2011 Obesity-mediated inflammatory microenvironment stimulates osteoclastogenesis and bone loss in mice.Experimental Gerontology.  46:43-52. 2011
2010 High fat diet-induced animal model of age-associated obesity and osteoporosis.Journal of Nutritional Biochemistry.  21:1162-1169. 2010
2010 Docosahexaenoic acid-enriched fish oil attenuates kidney disease and prolongs median and maximal life span of autoimmune lupus-prone mice.Journal of Immunology.  184:5280-5286. 2010
2010 Differential effects of conjugated linoleic acid isomers in insulin-resistant female C57Bl/6J mice.Journal of Nutritional Biochemistry.  21:332-337. 2010
2009 The fat-1 transgene in mice increases antioxidant potential, reduces pro-inflammatory cytokine levels, and enhances PPAR-gamma and SIRT-1 expression on a calorie restricted diet.Oxidative Medicine and Cellular Longevity.  2:307-316. 2009
2009 Effect of CLA isomers and their mixture on aging C57Bl/6J mice.Zeitschrift Ewrnahrungswissenschaft.  48:409-418. 2009
2009 Conjugated linoleic acid (CLA) prevents age-associated skeletal muscle loss.Biochemical and Biophysical Research Communications.  383:513-518. 2009
2006 Hypoglycemic activity of Cassia auriculata in neonatal streptozotocin-induced non-insulin dependent diabetes mellitus in ratsJournal of Natural Remedies.  6:14-18. 2006

Chapter

Year Title Altmetric
2013 Extracellular matrix biomarkers of adverse remodeling after myocardial infarction.  383-412. 2013

Education And Training

  • Doctor of Philosophy in Pharmacology, University of Mumbai
  • Full Name

  • Ganesh Halade
  • Blazerid

  • halade