Positions

Selected Publications

Academic Article

Year Title Altmetric
2018 Deletion of the glucagon receptor gene before and after experimental diabetes reveals differential protection from hyperglycemia.Molecular Metabolism.  17:28-38. 2018
2018 Hepatic Glucagon Receptor Signaling Enhances Insulin-Stimulated Glucose Disposal in Rodents.Diabetes.  67:2157-2166. 2018
2018 Glucagon Receptor Signaling Regulates Energy Metabolism via Hepatic Farnesoid X Receptor and Fibroblast Growth Factor 21.Diabetes.  67:1773-1782. 2018
2018 Antiretroviral therapy potentiates high-fat diet induced obesity and glucose intolerance.Molecular Metabolism.  12:48-61. 2018
2018 Dietary Manipulations That Induce Ketosis Activate the HPA Axis in Male Rats and Mice: A Potential Role for Fibroblast Growth Factor-21.Endocrinology.  159:400-413. 2018
2017 Duodenal endoluminal barrier sleeve alters gut microbiota of ZDF rats.International Journal of Obesity.  41:381-389. 2017
2016 LDB1 Regulates Energy Homeostasis During Diet-Induced Obesity.Endocrinology.  158:1289-1297. 2016
2016 Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease.Cell.  167:843-857.e14. 2016
2016 Fibroblast activation protein (FAP) as a novel metabolic target.Molecular Metabolism.  5:1015-1024. 2016
2016 Fibroblast growth factor 21 is required for beneficial effects of exercise during chronic high-fat feeding.Journal of applied physiology: respiratory, environmental and exercise physiology.  121:687-698. 2016
2015 FGF21 is not required for glucose homeostasis, ketosis or tumour suppression associated with ketogenic diets in mice.Diabetologia.  58:2414-2423. 2015
2015 A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents.Nature Medicine.  21:27-36. 2015
2015 GhrelinMolecular Metabolism.  4:437-460. 2015
2014 Duodenal nutrient exclusion improves metabolic syndrome and stimulates villus hyperplasia.Gut.  63:1238-1246. 2014
2014 Chromium enhances insulin responsiveness via AMPK.Journal of Nutritional Biochemistry.  25:565-572. 2014
2014 GLP-1R responsiveness predicts individual gastric bypass efficacy on glucose tolerance in rats.Diabetes.  63:505-513. 2014
2014 Both acyl and des-acyl ghrelin regulate adiposity and glucose metabolism via central nervous system ghrelin receptorsDiabetes.  63:122-131. 2014
2013 High-density lipoprotein maintains skeletal muscle function by modulating cellular respiration in mice.Circulation.  128:2364-2371. 2013
2013 Unimolecular dual incretins maximize metabolic benefits in rodents, monkeys, and humans.Science Translational Medicine.  5:209ra151. 2013
2013 GLP-1R agonism enhances adjustable gastric banding in diet-induced obese rats.Diabetes.  62:3261-3267. 2013
2013 Fibroblast growth factor 21 mediates specific glucagon actions.Diabetes.  62:1453-1463. 2013
2013 The orphan receptor Gpr83 regulates systemic energy metabolism via ghrelin-dependent and ghrelin-independent mechanisms.Nature Communications.  4:1968. 2013
2013 p62 links β-adrenergic input to mitochondrial function and thermogenesis.Journal of Clinical Investigation.  123:469-478. 2013
2012 Targeted estrogen delivery reverses the metabolic syndrome.Nature Medicine.  18:1847-1856. 2012
2012 Caloric restriction chronically impairs metabolic programming in mice.Diabetes.  61:2734-2742. 2012
2012 Acylation type determines ghrelin's effects on energy homeostasis in rodents.Endocrinology.  153:4687-4695. 2012
2012 Sirtuin 1 and sirtuin 3: physiological modulators of metabolism.Physiological Reviews.  92:1479-1514. 2012
2012 Restoration of leptin responsiveness in diet-induced obese mice using an optimized leptin analog in combination with exendin-4 or FGF21.Journal of Peptide Science.  18:383-393. 2012
2012 AMPK enhances insulin-stimulated GLUT4 regulation via lowering membrane cholesterol.Endocrinology.  153:2130-2141. 2012
2012 Fat-induced membrane cholesterol accrual provokes cortical filamentous actin destabilisation and glucose transport dysfunction in skeletal muscle.Diabetologia.  55:457-467. 2012
2012 Carbohydrate content of post-operative diet influences the effect of vertical sleeve gastrectomy on body weight reduction in obese rats.Obesity Surgery.  22:140-151. 2012
2012 MC4R dimerization in the paraventricular nucleus and GHSR/MC3R heterodimerization in the arcuate nucleus: is there relevance for body weight regulation?Neuroendocrinology.  95:277-288. 2012
2012 The GOAT-ghrelin system is not essential for hypoglycemia prevention during prolonged calorie restriction.PLoS ONE.  7:e32100. 2012
2011 Ghrelin receptor deficiency does not affect diet-induced atherosclerosis in low-density lipoprotein receptor-null miceFrontiers in Endocrinology.  2. 2011
2011 Evidence coupling increased hexosamine biosynthesis pathway activity to membrane cholesterol toxicity and cortical filamentous actin derangement contributing to cellular insulin resistance.Endocrinology.  152:3373-3384. 2011
2011 Neural regulation of cholesterol metabolismCurrent Opinion in Lipidology.  22:283-287. 2011
2011 A role for astrocytes in the central control of metabolism.Neuroendocrinology.  93:143-149. 2011
2010 The metabolic actions of glucagon revisited.Nature Reviews Endocrinology.  6:689-697. 2010
2010 Glucagon regulation of energy metabolism.Physiology and Behavior.  100:545-548. 2010
2010 CNS leptin action modulates immune response and survival in sepsis.Journal of Neuroscience.  30:6036-6047. 2010
2010 Erratum: Hexosamine biosynthesis pathway flux contributes to insulin resistance via altering membrane phosphatidylinositol 4,5-bisphosphate and cortical filamentous actin (Endocrinology (2009) 150, (1636-1645) DOI: 10.1210/en.2008-1102)Endocrinology.  151:2967. 2010
2009 Hexosamine biosynthesis pathway flux contributes to insulin resistance via altering membrane phosphatidylinositol 4,5-bisphosphate and cortical filamentous actin.Endocrinology.  150:1636-1645. 2009
2006 Development of congenic rat strains for alcohol consumption derived from the alcohol-preferring and nonpreferring rats.Behavior Genetics.  36:285-290. 2006
2005 Effect of polymorphism on expression of the neuropeptide Y gene in inbred alcohol-preferring and -nonpreferring rats.Neuroscience.  131:871-876. 2005
2004 Glutathione S-transferase 8-8 expression is lower in alcohol-preferring than in alcohol-nonpreferring rats.Alcoholism: Clinical and Experimental Research.  28:1622-1628. 2004
2003 Analyses of quantitative trait loci contributing to alcohol preference in HAD1/LAD1 and HAD2/LAD2 rats.Alcoholism: Clinical and Experimental Research.  27:1710-1717. 2003

Full Name

  • Kirk Habegger
  • Blazerid

  • habegger