Positions

Selected Publications

Academic Article

Year Title Altmetric
2022 Alpha Cell Thioredoxin-interacting Protein Deletion Improves Diabetes-associated Hyperglycemia and Hyperglucagonemia 2022
2021 Human Glucagon Expression Is under the Control of miR-320a 2021
2021 Human Glucagon Expression Is under the Control of miR-320a..  Endocrinology.  162. 2021
2020 Identification of an Anti-diabetic, Orally Available Small Molecule that Regulates TXNIP Expression and Glucagon Action.  Cell Metabolism.  32:353-365.e8. 2020
2016 Islet ChREBP-β is increased in diabetes and controls ChREBP-α and glucose-induced gene expression via a negative feedback loop.  Molecular Metabolism.  5:1208-1215. 2016
2016 MiR-204 targets PERK and regulates UPR signaling and β-cell apoptosis 2016
2014 MicroRNA-200 is induced by thioredoxin-interacting protein and regulates Zeb1 protein signaling and beta cell.  Journal of Biological Chemistry.  289:36275-36283. 2014
2014 Characterization of calmodulin-fas death domain interaction: An integrated experimental and computational study.  Biochemistry.  53:2680-2688. 2014
2014 Thioredoxin-interacting protein promotes islet amyloid polypeptide expression through miR-124a and FoxA2.  Journal of Biological Chemistry.  289:11807-11815. 2014
2014 Thioredoxin-interacting protein stimulates its own expression via a positive feedback loop 2014
2013 Thioredoxin-interacting protein regulates insulin transcription through microRNA-204.  Nature Medicine.  19:1141-1146. 2013
2013 FOXO1 competes with carbohydrate response element-binding protein (ChREBP) and inhibits thioredoxin-interacting protein (TXNIP) transcription in pancreatic beta cells.  Journal of Biological Chemistry.  288:23194-23202. 2013
2012 Calcium channel blockers act through nuclear factor Y to control transcription of key cardiac genes.  Molecular Pharmacology.  82:541-549. 2012
2012 Preventing β-cell loss and diabetes with calcium channel blockers.  Diabetes.  61:848-856. 2012
2012 Reduced CaM/FLIP binding by a single point mutation in c-FLIP L modulates Fas-mediated apoptosis and decreases tumorigenesis.  Laboratory Investigation.  92:82-90. 2012
2011 Calmodulin mediates Fas-induced FADD-independent survival signaling in pancreatic cancer cells via activation of Src-Extracellular Signal-regulated Kinase (ERK).  Journal of Biological Chemistry.  286:24776-24784. 2011
2011 Tamoxifen enhances therapeutic effects of gemcitabine on cholangiocarcinoma tumorigenesis.  Laboratory Investigation.  91:896-904. 2011
2009 Cloning and characterization of Prisilkin-39, a novel matrix protein serving a dual role in the prismatic layer formation from the oyster Pinctada fucata.  Journal of Biological Chemistry.  284:10841-10854. 2009
2007 N40, a novel nonacidic matrix protein from pearl oyster nacre, facilities nucleation of aragonite in vitro.  Biomacromolecules.  8:3597-3601. 2007
2007 Immunolocalization of an acid phosphatase from pearl oyster (Pinctada fucata) and its in vitro effects on calcium carbonate crystal formation 2007
2007 Different effects of Pb2+ and Cu2+ on immune and antioxidant enzyme activities in the mantle of Pinctada fucata.  Environmental Toxicology and Pharmacology.  24:122-128. 2007
2006 Metal accumulation and enzyme activities in gills and digestive gland of pearl oyster (Pinctada fucata) exposed to copper 2006
2006 Purification and partial characterization of two acid phosphatase forms from pearl oyster (Pinctada fucata) 2006

Education And Training

  • Doctor of Social or Behavioral Sciences in Biology / Biological Sciences, Tsinghua University 2007

    • Full Name

  • Gu Jing